Survival analysis of endometrial cancer patients with positive lymph nodes

International Journal of Gynecological Cancer

Volumn 23, Issue 5, 2013, Pages 861-868

  Brown, Aaron P ^a   Gaffney, David K ^b   Dodson, Mark K ^c,d   Soisson, A Pat ^c,d   Belnap, Thomas W ^e   Alleman, Kerry ^e   Sause, William T ^d,e  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b Radiation Oncology ^*  (United States)

^c UNIVERSITY OF UTAH   (United States)

^d INTERMOUNTAIN MEDICAL CENTER   (United States)

^e Radiation Oncology   (United States)

Author keywords

Adjuvant therapy; Endometrial cancer; Radiation therapy

Indexed keywords

CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER GRADING; CANCER PROGNOSIS; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CLINICAL ARTICLE; CONFERENCE PAPER; DIAGNOSTIC TEST ACCURACY STUDY; ENDOMETRIUM CANCER; FEMALE; HISTOPATHOLOGY; HUMAN; KAPLAN MEIER METHOD; LYMPH NODE METASTASIS; MEDICAL RECORD REVIEW; OVERALL SURVIVAL; PRIORITY JOURNAL; RETROSPECTIVE STUDY;

ADULT; AGED; AGED, 80 AND OVER; COMBINED MODALITY THERAPY; ENDOMETRIAL NEOPLASMS; FEMALE; FOLLOW-UP STUDIES; HUMANS; LYMPH NODES; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM GRADING; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PROGNOSIS; RETROSPECTIVE STUDIES; SURVIVAL RATE;

EID: 84880406410     PISSN: 1048891X     EISSN: 15251438     Source Type: Journal    
DOI: 10.1097/IGC.0b013e3182915c3e     Document Type: Conference Paper

References (28)

1. Altekruse S, Kosary C, KrapchoM, et al. SEER Cancer Statistics Review, 1975-2007; Based on November 2009 SEER Data Submission. Bethesda, MD: National Cancer Institute; 2010.
2. Susumu N, Sagae S, Udagawa Y, et al. Randomized phase III trial of pelvic radiotherapy versus cisplatin-based combined chemotherapy in patients with intermediate-and high-risk endometrial cancer: A Japanese Gynecologic Oncology Group study. Gynecol Oncol. 2008;108:226-233.
3. Randall ME, Filiaci VL, Muss H, et al. Randomized phase III trial of whole-abdominal irradiation versus doxorubicin and cisplatin chemotherapy in advanced endometrial carcinoma: A Gynecologic Oncology Group Study. J Clin Oncol. 2006;24:36-44.
4. Koh WJ, Tran AB, Douglas JG, et al. Radiation therapy in endometrial cancer. Best Pract Res Clin Obstet Gynaecol. 2001;15:417-432.
5. Hogberg T. Adjuvant chemotherapy in endometrial carcinoma: Overview of randomised trials. Clin Oncol (R Coll Radiol). 2008;20:463-469.
6. National Comprehensive Cancer Network Clinical Practice Guidelines: Uterine Neoplasms. 2010. Available at: Www.nccn.org.
7. Polterauer S, Khalil S, Zivanovic O, et al. Prognostic value of lymph node ratio and clinicopathologic parameters in patients diagnosed with stage IIIC endometrial cancer. Obstet Gynecol. 2012;119:1210-1218.
8. Schmid S, Hsu IC, Hu JM, et al. Adjuvant radiation therapy in stage III node-positive uterine cancer. Gynecol Oncol. 2009; 115:239-243.
9. Bristow RE, Zahurak ML, Alexander CJ, et al. FIGO stage IIIC endometrial carcinoma: Resection of macroscopic nodal disease and other determinants of survival. Int J Gynecol Cancer. 2003;13:664-672.
10. Hoekstra AV, Kim RJ, Small W Jr, et al. FIGO stage IIIC endometrial carcinoma: Prognostic factors and outcomes. Gynecol Oncol. 2009;114:273-278.
11. Mundt AJ, Murphy KT, Rotmensch J, et al. Surgery and postoperative radiation therapy in FIGO stage IIIC endometrial carcinoma. Int J Radiat Oncol Biol Phys. 2001;50: 1154-1160.
12. Rossi PJ, Jani AB, Horowitz IR, et al. Adjuvant brachytherapy removes survival disadvantage of local disease extension in stage IIIC endometrial cancer: A SEER registry analysis. Int J Radiat Oncol Biol Phys. 2008;70:134-138.
13. Klopp AH, Jhingran A, Ramondetta L, et al. Node-positive adenocarcinoma of the endometrium: Outcome and patterns of recurrence with and without external beam irradiation. Gynecol Oncol. 2009;115:6-11.
14. McMeekin DS, Lashbrook D, Gold M, et al. Analysis of FIGO stage IIIC endometrial cancer patients. Gynecol Oncol. 2001;81:273-278.
15. Watari H, Todo Y, Takeda M, et al. Lymph-vascular space invasion and number of positive para-aortic node groups predict survival in node-positive patients with endometrial cancer. Gynecol Oncol. 2005;96:651-657.
16. Touboul E, Belkacemi Y, Buffat L, et al. Adenocarcinoma of the endometrium treated with combined irradiation and surgery: Study of 437 patients. Int J Radiat Oncol Biol Phys. 2001;50:81-97.
17. Chang SJ, Kong TW, Kim WY, et al. Lymph-vascular space invasion as a significant risk factor for isolated para-aortic lymph node metastasis in endometrial cancer: A study of 203 consecutive patients. Ann Surg Oncol. 2011;18:58-64.
18. Guntupalli SR, Zighelboim I, Kizer NT, et al. Lymphovascular space invasion is an independent risk factor for nodal disease and poor outcomes in endometrioid endometrial cancer. Gynecol Oncol. 2012;124:31-35.
19. Simpkins F, Papadia A, Kunos C, et al. Patterns of recurrence in stage I endometrioid endometrial adenocarcinoma with lymphovascular space invasion. Int J Gynecol Cancer. 2013;23:98-104.
20. Keys HM, Roberts JA, Brunetto VL, et al. A phase III trial of surgery with or without adjunctive external pelvic radiation therapy in intermediate risk endometrial adenocarcinoma: A Gynecologic Oncology Group study. Gynecol Oncol. 2004; 92:744-751.
21. Creutzberg CL, van Putten WL, Koper PC, et al. Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: Multicentre randomised trial. PORTEC Study Group. Post operative radiation therapy in endometrial carcinoma. Lancet. 2000;355:1404-1411.
22. Blake P, Swart AM, Orton J, et al. Adjuvant external beam radiotherapy in the treatment of endometrial cancer (MRC ASTEC and NCIC CTG EN.5 randomised trials): Pooled trial results, systematic review, and meta-analysis. Lancet. 2009; 373:137-146.
23. Johnson N, Cornes P. Survival and recurrent disease after postoperative radiotherapy for early endometrial cancer: Systematic reviewandmeta-analysis. BJOG. 2007;114:1313-1320.
24. Lee CM, Szabo A, Shrieve DC, et al. Frequency and effect of adjuvant radiation therapy among women with stage I endometrial adenocarcinoma. JAMA. 2006;295:389-397.
25. Kuoppala T, Maenpaa J, Tomas E, et al. Surgically staged high-risk endometrial cancer: Randomized study of adjuvant radiotherapy alone vs. sequential chemo-radiotherapy. Gynecol Oncol. 2008;110:190-195.
26. Maggi R, Lissoni A, Spina F, et al. Adjuvant chemotherapy vs radiotherapy in high-risk endometrial carcinoma: Results of a randomised trial. Br J Cancer. 2006;95:266-271.
27. Hogberg T, Signorelli M, de Oliveira CF, et al. Sequential adjuvant chemotherapy and radiotherapy in endometrial cancerYresults from two randomised studies. Eur J Cancer. 2010;46:2422-2431.
28. Johnson N, Bryant A, Miles T, et al. Adjuvant chemotherapy for endometrial cancer after hysterectomy. Cochrane Database Syst Rev. 2011;CD003175.