Anxiety, pCO2 and cerebral blood flow

International Journal of Psychophysiology

Volumn 89, Issue 1, 2013, Pages 72-77

  Van den Bergh, Omer ^a   Zaman, Jonas ^a   Bresseleers, Johan ^a   Verhamme, Peter ^b   Van Diest, Ilse ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

Anxiety; Cerebral blood flow; CO2; Middle cerebral artery; Shock; Transcranial Doppler ultrasonography

Indexed keywords

CARBON DIOXIDE;

ADULT; ANXIETY; ARTICLE; BLOOD CARBON DIOXIDE TENSION; BRAIN BLOOD FLOW; BREATHING; CONTROLLED STUDY; DOPPLER ECHOGRAPHY; END TIDAL CARBON DIOXIDE TENSION; FEMALE; HUMAN; HUMAN EXPERIMENT; HYPERVENTILATION; HYPOCAPNIA; MALE; MIDDLE CEREBRAL ARTERY; NORMAL HUMAN; VASOCONSTRICTION; VASODILATATION; ADOLESCENT; BLOOD; BRAIN CIRCULATION; BREATHING MECHANICS; CBF; CBFV; CEREBRAL BLOOD FLOW VELOCITY; CO(2); ELECTROSTIMULATION; FEAR; FETCO(2); FRACTIONAL END-TIDAL CONCENTRATION OF CO(2); HYPERCAPNIA; MCA; METABOLISM; PARTIAL ARTERIAL CO(2) PRESSURE; PATHOPHYSIOLOGY; PCO(2); PHYSIOLOGY; PSYCHOLOGICAL ASPECT; REGRESSION ANALYSIS; SHOCK; STATISTICAL ANALYSIS; TCD; TRANSCRANIAL DOPPLER ULTRASONOGRAPHY; YOUNG ADULT; PSYCHOLOGY;

ANXIETY; CBF; CBFV; CEREBRAL BLOOD FLOW; CEREBRAL BLOOD FLOW VELOCITY; CO(2); FETCO(2); FRACTIONAL END-TIDAL CONCENTRATION OF CO(2); MCA; MIDDLE CEREBRAL ARTERY; PARTIAL ARTERIAL CO(2) PRESSURE; PCO(2); SHOCK; TCD; TRANSCRANIAL DOPPLER ULTRASONOGRAPHY;

ADOLESCENT; ADULT; ANXIETY; CARBON DIOXIDE; CEREBROVASCULAR CIRCULATION; DATA INTERPRETATION, STATISTICAL; ELECTRIC STIMULATION; FEAR; FEMALE; HUMANS; HYPERCAPNIA; HYPOCAPNIA; MALE; MIDDLE CEREBRAL ARTERY; REGRESSION ANALYSIS; RESPIRATORY MECHANICS; ULTRASONOGRAPHY, DOPPLER, TRANSCRANIAL; YOUNG ADULT;

EID: 84880356017     PISSN: 01678760     EISSN: 18727697     Source Type: Journal    
DOI: 10.1016/j.ijpsycho.2013.05.011     Document Type: Article

References (55)

1. Abelson J.L., Weg J.G., Nesse R.M., Curtis G.C. Persistent respiratory irregularity in patients with panic disorder. Biological Psychiatry 2001, 49(7):588-595.
2. Alkin T., Tural U., Onur E., Oztürk V., Monkul E.S., Kutluk K. Basilar artery blood flow velocity changes in patients with panic disorder following 35% carbon dioxide challenge. Progress in Neuro-Psychopharmacology and Biological Psychiatry 2007, 31(1):115-122.
3. Aronson T.A., Logue C.M. Phenomenology of panic attacks: a descriptive study of panic disorder patients' self-reports. The Journal of Clinical Psychiatry 1988, 49(1):8-13.
4. Ball S., Shekhar A. Basilar artery response to hyperventilation in panic disorder. The American Journal of Psychiatry 1997, 154(11):1603-1604.
5. Bishop C.C.R., Powell S., Rutt D., Browse N.L. Transcranial Doppler measurement of middle cerebral-artery blood-flow velocity - a validation study. Stroke 1986, 17(5):913-915.
6. Bresseleers J., Van Diest I., De Peuter S., Verhamme P., Van den Bergh O. Feeling lightheaded: the role of cerebral blood flow. Psychosomatic Medicine 2010, 72:672-680.
7. Cannistraro P., Rauch S. Neural circuitry of anxiety: evidence from structural and functional neuroimaging studies. Psychopharmacology Bulletin 2003, 37(4):8-25.
8. Cerisoli M., Amore M., Campanile S., Scardovi F., Borromei A., Alvisi C. Evaluating CBF velocity changes with transcranial Doppler ultrasound. The American Journal of Psychiatry 1996, 153:447.
9. Cohen J. Statistical Power Analysis for the Behavioral Sciences 1988, Erlbaum, Hillsdale, New Jersey. Second ed.
10. 2 on cerebral arterial diameter in man. Journal of Clinical Anesthesia 1998, 10(8):646-651.
11. Duschek S., Schandry R. Functional transcranial Doppler sonography as a tool in psychophysiological research. Psychophysiology 2003, 40(3):436-454.
12. Duschek S., Hellmann N., Merzoug K., Reyes del Paso G.A., Werner N.S. Cerebral blood flow dynamics during pain processing investigated by functional transcranial Doppler sonography. Pain Medicine 2012, 13:419-426.
13. Cerebral Blood Flow and Metabolism 2002, Lippincott Williams and Wilkins, Philadelphia. Second ed. L. Edvinsson, D.N. Krause (Eds.).
14. 2. Acta Physiologica Scandinavica 1987, 129(2):157.
15. Engel K., Bandelow B., Gruber O., Wedekind D. Neuroimaging in anxiety disorders. Journal of Neural Transmission 2009, 116(6):703-716.
16. Estevez A.Y., Phillis J.W. Hypercapnia-induced increases in cerebral blood flow: roles of adenosine, nitric oxide and cortical arousal. Brain Research 1997, 758(1-2):1-8.
17. Gecici O., Acar M., Haktanir A., Emul M., Demirel R., Yucel A., et al. Evaluation of cerebral blood flow volume using color duplex sonography in patients with untreated panic disorder. Psychiatry and Clinical Neurosciences 2005, 59(6):676-682.
18. Giardino N.D., Friedman S.D., Dager S.R. Anxiety, respiration, and cerebral blood flow: implications for functional brain imaging. Comprehensive Psychiatry 2007, 48(2):103-112.
19. Giller C.A., Bowman G., Dyer H., Mootz L., Krippner W., Loftus C.M., et al. Cerebral artery diameters during changes in blood-pressure and carbon-dioxide during craniometry. Neurosurgery 1993, 32(5):737-742.
20. Grubb B.P., Gerard G., Roush K., Temesy-Armos P., Montford P., Elliott L., Hahn H., Brewster P. Cerebral vasoconstriction during head-upright tilt-induced vasovagal syncope: a paradoxic and unexpected response. Circulation 1991, 84:1157-1164.
21. Gur R.C., Gur R.E., Skolnick B.E., Resnick S.M., Silver F.L., Chawluk J., et al. Effects of task-difficulty on regional cerebral blood-flow - relationships with anxiety and performance. Psychophysiology 1988, 25(4):392-399.
22. Hoehnsaric R., McLeod D.R. The peripheral sympathetic nervous-system - it's role in normal and pathologic anxiety. Psychiatric Clinics of North America 1988, 11(2):375-386.
23. Hoge E.A., Tamrakar S.M., Christian K.M., Mahara N., Nepal M.K., Pollack M.H., et al. Cross-cultural differences in somatic presentation in patients with generalized anxiety disorder. The Journal of Nervous and Mental Disease 2006, 194(12):962-966.
24. Ingvar D.H., Lassen N.A. Regulation of cerebral blood flow. Brain Metabolism and Cerebral Disorders 1976, 181-206. Spectrum Publications, Inc., New York. H.E. Himwich (Ed.).
25. Jordan J., Shannon J.R., Diedrich A., Black B., Costa F., Robertson D., et al. Interaction of carbon dioxide and sympathetic nervous system activity in the regulation of cerebral perfusion in humans. Hypertension 2000, 36(3):383-388.
26. Kelley R.E., Chang J.Y., Scheinman N.J., Levin B.E., Duncan R.C., Lee S.C. Transcranial Doppler assessment of cerebral flow velocity during cognitive tasks. Stroke 1992, 23(1):9-14.
27. Kety S.S., Schmidt C.F. The effects of active and passive hyperventilation on cerebral blood flow, cerebral oxygen consumption, cardiac output, and blood pressure of normal young men. The Journal of Clinical Investigation 1946, 25(1):107.
28. Kim J., Gorman J. The psychobiology of anxiety. Clinical Neuroscience Research 2005, 4(5-6):335-347.
29. 2 and Diamox test - decreased reliability by changes of the vessel diameter. Cerebrovascular Diseases 1995, 5(6):397-402.
30. Levine B.D., Giller C.A., Lane L.D., Buckey J.C., Blomqvist C.G. Cerebral versus systemic hemodynamics during graded orthostatic stress in humans. Circulation 1994, 90:298-306.
31. Lindegaard K.F., Lundar T., Wiberg J., Sjoberg D., Aaslid R., Nornes H. Variations in middle cerebral-artery blood-flow investigated with noninvasive transcranial blood velocity-measurements. Stroke 1987, 18(6):1025-1030.
32. Masaoka Y., Homma I. The effect of anticipatory anxiety on breathing and metabolism in humans. Respiration Physiology 2001, 128(2):171-177.
33. Mathew R.J., Wilson W.H. Anxiety and cerebral blood-flow. The American Journal of Psychiatry 1990, 147(7):838-849.
34. Mathew R.J., Wilson W.H., Nicassio P.M. Cerebral ischemic symptoms in anxiety disorders. The American Journal of Psychiatry 1987, 144(2):265.
35. Mathew R.J., Wilson W.H., Humphreys D., Lowe J.V., Wiethe K.E. Cerebral vasodilation and vasoconstriction associated with acute anxiety. Biological Psychiatry 1997, 41(7):782-795.
36. Owega A., Sabri O., Klingelhofer J., Albers M. Cerebral blood flow velocity in untreated panic disorder patients: a transcranial Doppler ultrasonography study. Biological Psychiatry 2001, 50(4):299-304.
37. Panerai R.B., Carey B.J., Potter J.F. Short-term variability of cerebral blood flow velocity responses to arterial blood pressure transients. Ultrasound in Medicine & Biology 2003, 29:31-38.
38. 2 in humans. Journal of Applied Physiology 1996, 81(3):1084-1095.
39. Sandor P. Nervous control of the cerebrovascular system: doubts and facts. Neurochemistry International 1999, 35(3):237-259.
40. Santalucia P., Feldmann E. The basic transcranial Doppler examination: technique and anatomy. Transcranial Doppler Ultrasonography 1993, Butterworth Heinemann, Boston. V.L. Babikian, L.R. Wechsler (Eds.).
41. Schmidt P., Krings T., Willmes K., Roessler F., Reul J., Thron A. Determination of cognitive hemispheric lateralization by "functional" transcranial Doppler cross-validated by functional MRI. Stroke 1999, 30(5):939-945.
42. Spielberger C.D., Gorsuch R.C., Lushene R.E. Manual for the State Trait Anxiety Inventory 1970, Consulting Psychologists Press, Palo Alto, CA.
43. Spruyt A., Clarysse J., Vansteenwegen D., Baeyens F. Affect 4.0: a free software package for implementing psychological and psychophysiological experiments. Experimental Psychology 2010, 57(1):36-45.
44. Staab J.P., Ruckenstein M.J. Which comes first? Psychogenic dizziness versus otogenic anxiety. Laryngoscope 2003, 113(10):1714-1718.
45. Stroobant N., Vingerhoets G. Transcranial Doppler ultrasonography monitoring of cerebral hemodynamics during performance of cognitive tasks: a review. Neuropsychology Review 2000, 10(4):213-231.
46. Van Breukelen G.J.P., Van Dijk K.R.A. Use of covariates in randomized controlled trials. Journal of the International Neuropsychological Society 2007, 13:903-904.
47. Van der Ploeg H.M., Defares P.B., Spielberger C.D. Handleiding bij de zelf-beoordelings vragenlijst ZBV: Een nederlandstalige bewerking Van de Spielberger State-Trait Anxiety Inventory, STAI-DY 1980, Swets and Zeitlinger B.V., Lisse, The Netherlands.
48. Van Diest I., Winters W., Devriese S., Vercamst E., Han J.N., Van de Woestijne K.P., et al. Hyperventilation beyond fight/flight: respiratory responses during emotional imagery. Psychophysiology 2001, 38(6):961-968.
49. Van Diest I., De Peuter S., Devriese S., Wellens E., Van de Woestijne K.P., Van den Bergh O. Imagined risk of suffocation as a trigger for hyperventilation. Psychosomatic Medicine 2005, 67:813-819.
50. van Lieshout J.J., Secher N.H. Point: counterpoint: sympathetic activity does/does not influence cerebral blood flow. Journal of Applied Physiology 2008, 105(4):1364-1366.
51. Vlemincx E., Abelson J.L., Lehrer P.M., Davenport P.W., Van Diest I., Van den Bergh O. Respiratory variability and sighing: a psychophysiological reset model. Biological Psychology 2013, 93:24-32.
52. White H., Venkatesh B. Applications of transcranial Doppler in the ICU: a review. Intensive Care Medicine 2006, 32(7):981-994.
53. Wise R.G., Ide K., Poulin M.J., Tracey I. Resting fluctuations in arterial carbon dioxide induce significant low frequency variations in BOLD signal. NeuroImage 2004, 21:1652-1664.
54. Wollburg E., Meuret A.E., Conrad A., Roth W.T., Kim S. Psychophysiological reactions to two levels of voluntary hyperventilation in panic disorder. Journal of Anxiety Disorders 2008, 22(5):886-898.
55. Zohar J., Insel T.R., Berman K.F., Foa E.B., Hill J.L., Weinberger D.R. Anxiety and cerebral blood-flow during behavioral challenge: dissociation of central from peripheral and subjective measures. Archives of General Psychiatry 1989, 46(6):505-510.