Detection of CYP2E1, a genetic biomarker of susceptibility to benzene metabolism toxicity in immortal human lymphocytes derived from the Han Chinese population

Biomedical and Environmental Sciences

Volumn 24, Issue 3, 2011, Pages 300-309

  Zhang, Juan ^a   Yin, Lihong ^a   Liang, Geyu ^a   Liu, Ran ^a   Fan, Kaihong ^a   Pu, Yuepu ^a  

^a SOUTHEAST UNIVERSITY   (China)

Author keywords

Benzene; Cytochrome P450 2E1; Genetic biomarker; Human immortalized B lymphocytes; Phenol; Single nucleotide polymorphism

Indexed keywords

BENZENE; CYTOCHROME P450 2E1; PHENOL;

ADOLESCENT; ADULT; ARTICLE; ASIAN; CELL LINE; CELL PROLIFERATION; DRUG EFFECT; GENETICS; HUMAN; LYMPHOCYTE; METABOLISM; MIDDLE AGED;

ADOLESCENT; ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; BENZENE; CELL LINE; CELL PROLIFERATION; CYTOCHROME P-450 CYP2E1; HUMANS; LYMPHOCYTES; MIDDLE AGED; PHENOL; YOUNG ADULT;

EID: 79960823312     PISSN: 08953988     EISSN: None     Source Type: Journal    
DOI: 10.3967/0895-3988.2011.03.014     Document Type: Article

References (39)

1. PF Infante, RA Rinsky, JK Wagoner et al. Leukemia in benzene workers Lancet 2 1977 76 78
2. MR Lovern, ME Maris, PM Schlosser Use of a mathematical model of rodent in vitro benzene metabolism to predict human in vitro metabolism data Carcinogenesis 20 1999 1511 1520 (Pubitemid 29385438)
3. AK Bauer, B Faiola, DJ Abernethy et al. Genetic susceptibility to benzene-induced toxicity: Role of NADPH: Quinone oxidoreductase-1 Cancer Res 63 2003 929 935 (Pubitemid 36278421)
4. J Zhang, FY Zhu, YP Pu et al. Analysis of multiple single nucleotide polymorphisms (SNP) of myeloperoxidase (MPO) to screen for genetic markers associated with acute leukemia in Chinese Han population Toxicol Environ Health A 70 2007 901 907 (Pubitemid 46699719)
5. JZ Liu, LY Hao, TY Wen et al. Indoor decoration and sick building syndrome J Environ Health 19 2002 23 25 (In Chinese).
6. GF Kalf Recent advances in the metabolism and toxicity of benzene Crit Rev Toxico 18 1987 141 159
7. IG Kessova, AI Cederbaum The effect of CYP2E1-dependent oxidant stress on activity of proteasomes in HepG2 cells J Pharmacol Exp Ther 315 2005 304 312 (Pubitemid 41380525)
8. P Sheets, G Carlson Kinetic factors involved in the metabolism of benzene in mouse lung and liver Toxicol Environ Health A 67 2004 421 430 (Pubitemid 38233930)
9. JL Valentine, SS Lee, MJ Seaton et al. Reduction of benzene metabolism and toxicity in mice that lack CYP2E1 expression Toxicol Appl Pharmacol 141 1996 205 213 (Pubitemid 26414367)
10. M Tsuchihashi-Makaya, M Serizawa, K Yanai et al. Gene-environmental interaction regarding alcohol-metabolizing enzymes in the Japanese general population Hypertens Res 32 2009 207 213
11. HP Rihs, G Triebig, P Werner et al. Association between genetic polymorphisms in styrene-metabolizing enzymes and biomarkers in styrene-exposed workers J Toxicol Environ Health 71 2008 866 873 (Pubitemid 352000709)
12. BN Chorley, X Wang, MR Campbell et al. Discovery and verification of functional single nucleotide polymorphisms in regulatory genomic regions: Current and developing technologies Mutat Res 659 2008 147 157
13. D Dougherty, S Garte, A Barchowsky et al. NQO1, MPO, CYP2E1, GSTT1, and GSTM1 polymorphisms and biological effects of benzene exposure-A literature review Toxicol Lett 182 2008 7 17
14. L LeMarchand, GR Wilkinson, LR Wilkens Genetic and dietary predictors of CYP2E1 activity: a phenotyping study in Hawaii Japanese using chlorzoxazone Cancer Epidemiol Biomarkers Prev 8 1999 495 500 (Pubitemid 29270332)
15. H Ju, B Lim, M Kim et al. SERPINE1 intron polymorphisms affecting gene expression are associated with diffuse-type gastric cancer susceptibility Cancer 116 2010 4248 4255
16. JW Watters, A Kraja, MA Meucci et al. Genome-wide discovery of loci influencing chemotherapy cytotoxicity Proc Natl Acad Sci U S A 101 2004 11809 11814 (Pubitemid 39095376)
17. MM Amoli, D Carthy, H Platt EBV Immortalization of human B lymphocytes separated from small volumes of cryo-preserved whole blood Int J Epidemiol 37 2008 41 45
18. VG Cheung, LK Conlin, TM Weber et al. Natural variation in human gene expression assessed in lymphoblastoid cells Nat Rev Genet 33 2003 422 425 (Pubitemid 36278862)
19. G Ulusoy, O Adali, TB Tumer et al. Significance of genetic polymorphisms at multiple loci of CYP2E1 in the risk of development of childhood acute lymphoblastic leukemia Oncology 72 2007 125 131 (Pubitemid 350249140)
20. M Krajinovic, H Sinnett, C Richer et al. Role of NQO1, MPO and CYP2E1 genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia Int J Cancer 97 2002 230 236 (Pubitemid 34019960)
21. G Ulusoy, E Arin, O Adali Genotype and allele frequencies of polymorphic CYP2E1 in the Turkish population Arch Toxicol 81 2007 711 718 (Pubitemid 47512602)
22. K Pahan, BT Smith, AK Singh et al. Cytochrome P-450 2E1 in rat liver peroxisomes: downregulation by ischemia/reperfusion-induced oxidative stress Free Radic Biol Med 23 1997 963 971 (Pubitemid 27451282)
23. M Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Ana Biochem 72 1976 248 254
24. K Konca, A Lankoff, A Banasik et al. A cross-platform public domain PC image-analysis program for the comet assay Mutat Res 534 2003 15 20 (Pubitemid 36015835)
25. MF Ellahuene, LP Perez-Alzola, M Farfan-Urzua et al. Preliminary evaluation of DNA damage related with the smoking habit measured by the comet assay in whole blood cells Cancer Epidemiol Biomarkers Prev 13 2004 1223 1229 (Pubitemid 38917912)
26. CA James, G Xin, SL Doty et al. Degradation of low molecular weight volatile organic compounds by plants genetically modified with mammalian cytochrome P450 2E1 Environ Sci Technol 42 2008 289 293
27. BI Ghanayem, U Hoffler Investigation of xenobiotics metabolism, genotoxicity, and carcinogenicity using Cyp2e1(-/-) mice Curr Drug Metab 8 2007 728 749 (Pubitemid 47578121)
28. D Anderson, TW Yu, DB McGregor Comet assay responses as indicator of carcinogen exposure Mutagenesis 13 1998 549 555
29. S Hayashi, J Watanabe, K Kawajiri Genetic polymorphisms in the 5′-flanking region change transcriptional regulation of the human cytochrome P450IIE1 gene J Biochem 110 1991 559 565
30. LL Marchand, GR Wilkinson, LR Wilkens Genetic and dietary predictors of CYP2E1 activity: A phenotyping study in Hawaii Japanese using chlorzoxazone Cancer Epidemiol Biomarkers Prev 8 1998 495 500 (Pubitemid 29270332)
31. C Weisel, R Yu, A Roy et al. Biomarkers of environmental benzene exposure. Environ Health Perspect 104 1996 1141 1146 (Pubitemid 27046139)
32. S Fustinoni, D Consonni, L Campo et al. Monitoring low benzene exposure: comparative evaluation of urinary biomarkers influence of cigarette smoking and genetic polymorphisms Cancer Epidemiol Biomarkers Prev 14 2005 2237 2244 (Pubitemid 41603273)
33. S Chanvaivit, P Navasumrit, P Hunsonti et al. Exposure assessment of benzene in Thai workers, DNA-repair capacity and influence of genetic polymorphisms Mutat Res 626 2007 79 87 (Pubitemid 44895600)
34. SY Kim, JK Choi, YH Cho et al. Chromosomal aberrations in workers exposed to low levels of benzene: association with genetic polymorphisms Pharmacogenetics 14 2004 453 463
35. Y Chen, GL Li, ZY Ji et al. Genetic polymorphisms of NQO1, GSTT1. GSTM1 and susceptibility to chronic BP Chin J Ind Hyg Occup 23 2005 1 5
36. Y Zhang, KJ Hughes, SH Zahm et al. Genetic variations in xenobiotic metabolic pathway genes, personal hair dye use, and risk of non-Hodgkin lymphoma Am J Epidemiol 170 2009 1222 1230
37. DG McCarver, R Byun, RN Hines et al. A genetic polymorphism in the regulatory sequences of human CYP2E1: association with increased chlorzoxazone hydroxylation in the presence of obesity and ethanol intake Toxicol Appl Pharmacol 152 1998 276 281 (Pubitemid 28498696)
38. NJ Schork, JP Gardner, L Zhang et al. Genomic association/linkage of sodium lithium counter transport in CEPH pedigrees Hypertension 40 2002 619 628 (Pubitemid 35278596)
39. KY Jen, VG Cheung Identification of novel p53 target genes in ionizing radiation response Cancer Res 65 2005 7666 7673 (Pubitemid 41297240)