Repression of miR-143 Mediates Cr (VI)-Induced Tumor Angiogenesis via IGF-IR/IRS1/ERK/IL-8 Pathway

Toxicological Sciences

Volumn 134, Issue 1, 2013, Pages 26-38

  He, Jun ^a   Qian, Xu ^b   Carpenter, Richard ^a   Xu, Qing ^b   Wang, Lin ^b   Qi, Yanting ^a   Wang, Zi Xuan ^a   Liu, Ling Zhi ^a   Jiang, Bing Hua ^a,b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Chromium (VI); IGF IR IRS1; Lung cancer; MiR 143; Tumor angiogenesis

Indexed keywords

CHROMIUM; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN RECEPTOR SUBSTRATE 1; INTERLEUKIN 8; MICRORNA 143; MITOGEN ACTIVATED PROTEIN KINASE; SOMATOMEDIN C RECEPTOR; CARCINOGEN; CHROMIUM HEXAVALENT ION; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, MOUSE; MICRORNA; MIRN143 MICRORNA, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; EPITHELIUM CELL; GENE EXPRESSION; GENE REPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LONG TERM EXPOSURE; MALE; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; TUMOR MODEL; TUMOR VASCULARIZATION; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CELL LINE; CELL TRANSFORMATION; DOWN REGULATION; DRUG EFFECTS; GENETICS; IMMUNOLOGY; LUNG TUMOR; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); NUDE MOUSE; PATHOLOGY;

ANIMALS; CARCINOGENS, ENVIRONMENTAL; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; CHROMIUM; DOWN-REGULATION; EPITHELIAL CELLS; HUMANS; INSULIN RECEPTOR SUBSTRATE PROTEINS; INTERLEUKIN-8; LUNG NEOPLASMS; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; MICE, NUDE; MICRORNAS; NEOVASCULARIZATION, PATHOLOGIC; RECEPTOR, IGF TYPE 1; UP-REGULATION;

EID: 84880306518     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft101     Document Type: Article

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