메뉴 건너뛰기




Volumn 91, Issue 5, 2013, Pages 445-452

Profile of intraocular tumour necrosis factor-α and interleukin-6 in diabetic subjects with different degrees of diabetic retinopathy

Author keywords

aqueous humour; diabetic retinopathy; inflammation; interleukin 6; tumour necrosis factor ; vitreous

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; PROTEIN KINASE C; TUMOR NECROSIS FACTOR ALPHA;

EID: 84880303028     PISSN: 1755375X     EISSN: 17553768     Source Type: Journal    
DOI: 10.1111/j.1755-3768.2012.02430.x     Document Type: Article
Times cited : (56)

References (44)
  • 2
    • 56049091016 scopus 로고    scopus 로고
    • Assessment of selected adhesion molecule and proinflammatory cytokine levels in the vitreous body of patients with type 2 diabetes - Role of the inflammatory-immune process in the pathogenesis of proliferative diabetic retinopathy
    • Adamiec-Mroczek J, &, Oficjalska-Mlynczak J, (2008): Assessment of selected adhesion molecule and proinflammatory cytokine levels in the vitreous body of patients with type 2 diabetes-role of the inflammatory-immune process in the pathogenesis of proliferative diabetic retinopathy. Graefes Arch Clin Exp Ophthalmol 246: 1665-1670.
    • (2008) Graefes Arch Clin Exp Ophthalmol , vol.246 , pp. 1665-1670
    • Adamiec-Mroczek, J.1    Oficjalska-Mlynczak, J.2
  • 3
    • 75449101393 scopus 로고    scopus 로고
    • Roles of endothelin-1 and selected proinflammatory cytokines in the pathogenesis of proliferative diabetic retinopathy: Analysis of vitreous samples
    • Adamiec-Mroczek J, Oficjalska-Mlynczak J, &, Misiuk-Hojlo M, (2010): Roles of endothelin-1 and selected proinflammatory cytokines in the pathogenesis of proliferative diabetic retinopathy: analysis of vitreous samples. cytokine 49: 269-274.
    • (2010) Cytokine , vol.49 , pp. 269-274
    • Adamiec-Mroczek, J.1    Oficjalska-Mlynczak, J.2    Misiuk-Hojlo, M.3
  • 4
    • 42449135678 scopus 로고    scopus 로고
    • Immunological mechanisms in the pathogenesis of diabetic retinopathy
    • Adamis AP, &, Berman AJ, (2008): Immunological mechanisms in the pathogenesis of diabetic retinopathy. Semin Immunopathol 30: 65-84.
    • (2008) Semin Immunopathol , vol.30 , pp. 65-84
    • Adamis, A.P.1    Berman, A.J.2
  • 5
    • 0027942607 scopus 로고
    • Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders
    • Aiello LP, Avery RL, Arrigg PG, et al., (1994): Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med 331: 1480-1487.
    • (1994) N Engl J Med , vol.331 , pp. 1480-1487
    • Aiello, L.P.1    Avery, R.L.2    Arrigg, P.G.3
  • 6
    • 77955402723 scopus 로고    scopus 로고
    • Adipocytokines in atherothrombosis: Focus on platelets and vascular smooth muscle cells
    • Anfossi G, Russo I, Doronzo G, Pomero A, &, Trovati M, (2010): Adipocytokines in atherothrombosis: focus on platelets and vascular smooth muscle cells. Mediators Inflamm 2010: 174341.
    • (2010) Mediators Inflamm , vol.2010 , pp. 174341
    • Anfossi, G.1    Russo, I.2    Doronzo, G.3    Pomero, A.4    Trovati, M.5
  • 7
    • 78049280268 scopus 로고    scopus 로고
    • TNF-alpha signals through PKCzeta/NF-kappaB to alter the tight junction complex and increase retinal endothelial cell permeability
    • Aveleira CA, Lin CM, Abcouwer SF, Ambrosio AF, &, Antonetti DA, (2010): TNF-alpha signals through PKCzeta/NF-kappaB to alter the tight junction complex and increase retinal endothelial cell permeability. Diabetes 59: 2872-2882.
    • (2010) Diabetes , vol.59 , pp. 2872-2882
    • Aveleira, C.A.1    Lin, C.M.2    Abcouwer, S.F.3    Ambrosio, A.F.4    Antonetti, D.A.5
  • 8
    • 33746760142 scopus 로고    scopus 로고
    • Clinical validation of a link between TNF-alpha and the glycosylation enzyme core 2 GlcNAc-T and the relationship of this link to diabetic retinopathy
    • Ben-Mahmud BM, Chan WH, Abdulahad RM, Datti A, Orlacchio A, Kohner EM, &, Chibber R, (2006): Clinical validation of a link between TNF-alpha and the glycosylation enzyme core 2 GlcNAc-T and the relationship of this link to diabetic retinopathy. Diabetologia 49: 2185-2191.
    • (2006) Diabetologia , vol.49 , pp. 2185-2191
    • Ben-Mahmud, B.M.1    Chan, W.H.2    Abdulahad, R.M.3    Datti, A.4    Orlacchio, A.5    Kohner, E.M.6    Chibber, R.7
  • 9
    • 38449111027 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF) biology and cell death
    • Bertazza L, &, Mocellin S, (2008): Tumor necrosis factor (TNF) biology and cell death. Front Biosci 13: 2736-2743.
    • (2008) Front Biosci , vol.13 , pp. 2736-2743
    • Bertazza, L.1    Mocellin, S.2
  • 10
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • Brownlee M, (2001): Biochemistry and molecular cell biology of diabetic complications. Nature 414: 813-820.
    • (2001) Nature , vol.414 , pp. 813-820
    • Brownlee, M.1
  • 11
    • 28244500965 scopus 로고    scopus 로고
    • Interleukin (IL)-6, interleukin (IL)-8 levels and cellular composition of the vitreous humor in proliferative diabetic retinopathy, proliferative vitreoretinopathy, and traumatic proliferative vitreoretinopathy
    • Canataroglu H, Varinli I, Ozcan AA, Canataroglu A, Doran F, &, Varinli S, (2005): Interleukin (IL)-6, interleukin (IL)-8 levels and cellular composition of the vitreous humor in proliferative diabetic retinopathy, proliferative vitreoretinopathy, and traumatic proliferative vitreoretinopathy. Ocul Immunol Inflamm 13: 375-381.
    • (2005) Ocul Immunol Inflamm , vol.13 , pp. 375-381
    • Canataroglu, H.1    Varinli, I.2    Ozcan, A.A.3    Canataroglu, A.4    Doran, F.5    Varinli, S.6
  • 14
  • 15
    • 0035984887 scopus 로고    scopus 로고
    • Comparison of serum NO, TNF-alpha, IL-1beta, sIL-2R, IL-6 and IL-8 levels with grades of retinopathy in patients with diabetes mellitus
    • Doganay S, Evereklioglu C, Er H, Turkoz Y, Sevinc A, Mehmet N, &, Savli H, (2002): Comparison of serum NO, TNF-alpha, IL-1beta, sIL-2R, IL-6 and IL-8 levels with grades of retinopathy in patients with diabetes mellitus. Eye 16: 163-170.
    • (2002) Eye , vol.16 , pp. 163-170
    • Doganay, S.1    Evereklioglu, C.2    Er, H.3    Turkoz, Y.4    Sevinc, A.5    Mehmet, N.6    Savli, H.7
  • 16
    • 77951703383 scopus 로고    scopus 로고
    • Diabetic macular oedema: Physical, physiological and molecular factors contribute to this pathological process
    • Ehrlich R, Harris A, Ciulla TA, Kheradiya N, Winston DM, &, Wirostko B, (2010): Diabetic macular oedema: physical, physiological and molecular factors contribute to this pathological process. Acta Ophthalmol 88: 279-291.
    • (2010) Acta Ophthalmol , vol.88 , pp. 279-291
    • Ehrlich, R.1    Harris, A.2    Ciulla, T.A.3    Kheradiya, N.4    Winston, D.M.5    Wirostko, B.6
  • 17
    • 0025845943 scopus 로고
    • Grading diabetic retinopathy from stereoscopic color fundus photographs - An extension of the modified Airlie House classification. ETDRS report number 10. Early Treatment Diabetic Retinopathy Study Research Group
    • ETDRS group
    • ETDRS group (1991): Grading diabetic retinopathy from stereoscopic color fundus photographs-an extension of the modified Airlie House classification. ETDRS report number 10. Early Treatment Diabetic Retinopathy Study Research Group. Ophthalmology 98: 786-806.
    • (1991) Ophthalmology , vol.98 , pp. 786-806
  • 19
    • 0036147042 scopus 로고    scopus 로고
    • Increased levels of vascular endothelial growth factor and interleukin-6 in the aqueous humor of diabetics with macular edema
    • Funatsu H, Yamashita H, Noma H, Mimura T, Yamashita T, &, Hori S, (2002): Increased levels of vascular endothelial growth factor and interleukin-6 in the aqueous humor of diabetics with macular edema. Am J Ophthalmol 133: 70-77.
    • (2002) Am J Ophthalmol , vol.133 , pp. 70-77
    • Funatsu, H.1    Yamashita, H.2    Noma, H.3    Mimura, T.4    Yamashita, T.5    Hori, S.6
  • 20
    • 57949110908 scopus 로고    scopus 로고
    • Association of vitreous inflammatory factors with diabetic macular edema
    • Funatsu H, Noma H, Mimura T, Eguchi S, &, Hori S, (2009): Association of vitreous inflammatory factors with diabetic macular edema. Ophthalmology 116: 73-79.
    • (2009) Ophthalmology , vol.116 , pp. 73-79
    • Funatsu, H.1    Noma, H.2    Mimura, T.3    Eguchi, S.4    Hori, S.5
  • 21
    • 33750621975 scopus 로고    scopus 로고
    • Simultaneous quantification of 17 immune mediators in aqueous humour from patients with corneal rejection
    • Funding M, Hansen TK, Gjedsted J, &, Ehlers N, (2006): Simultaneous quantification of 17 immune mediators in aqueous humour from patients with corneal rejection. Acta Ophthalmol Scand 84: 759-765.
    • (2006) Acta Ophthalmol Scand , vol.84 , pp. 759-765
    • Funding, M.1    Hansen, T.K.2    Gjedsted, J.3    Ehlers, N.4
  • 22
    • 69949093803 scopus 로고    scopus 로고
    • Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications
    • Goldberg RB, (2009): Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications. J Clin Endocrinol Metab 94: 3171-3182.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 3171-3182
    • Goldberg, R.B.1
  • 23
    • 79958268827 scopus 로고    scopus 로고
    • Randomized trial evaluating short-term effects of intravitreal ranibizumab or triamcinolone acetonide on macular edema after focal/grid laser for diabetic macular edema in eyes also receiving panretinal photocoagulation
    • Googe J, Brucker AJ, Bressler NM, Qin H, Aiello LP, Antoszyk A, Beck RW, Bressler SB, Ferris FL III, Glassman AR, Marcus D, &, Stockdale CR, (2011): Randomized trial evaluating short-term effects of intravitreal ranibizumab or triamcinolone acetonide on macular edema after focal/grid laser for diabetic macular edema in eyes also receiving panretinal photocoagulation. Retina 31: 1009-1027.
    • (2011) Retina , vol.31 , pp. 1009-1027
    • Googe, J.1    Brucker, A.J.2    Bressler, N.M.3    Qin, H.4    Aiello, L.P.5    Antoszyk, A.6    Beck, R.W.7    Bressler, S.B.8    Ferris Iii, F.L.9    Glassman, A.R.10    Marcus, D.11    Stockdale, C.R.12
  • 24
    • 42549108719 scopus 로고    scopus 로고
    • TNF-alpha is an independent serum marker for proliferative retinopathy in type 1 diabetic patients
    • Gustavsson C, Agardh E, Bengtsson B, &, Agardh CD, (2008): TNF-alpha is an independent serum marker for proliferative retinopathy in type 1 diabetic patients. J Diabetes Complications 22: 309-316.
    • (2008) J Diabetes Complications , vol.22 , pp. 309-316
    • Gustavsson, C.1    Agardh, E.2    Bengtsson, B.3    Agardh, C.D.4
  • 25
    • 34547485312 scopus 로고    scopus 로고
    • The endothelium and vascular inflammation in diabetes
    • Hartge MM, Unger T, &, Kintscher U, (2007): The endothelium and vascular inflammation in diabetes. Diab Vasc Dis Res 4: 84-88.
    • (2007) Diab Vasc Dis Res , vol.4 , pp. 84-88
    • Hartge, M.M.1    Unger, T.2    Kintscher, U.3
  • 26
    • 24744435772 scopus 로고    scopus 로고
    • Directing transition from innate to acquired immunity: Defining a role for IL-6
    • Jones SA, (2005): Directing transition from innate to acquired immunity: defining a role for IL-6. J Immunol 175: 3463-3468.
    • (2005) J Immunol , vol.175 , pp. 3463-3468
    • Jones, S.A.1
  • 27
    • 41149099068 scopus 로고    scopus 로고
    • Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy
    • Kern TS, (2007): Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy. Exp Diabetes Res 2007: 95103.
    • (2007) Exp Diabetes Res , vol.2007 , pp. 95103
    • Kern, T.S.1
  • 28
    • 61349156849 scopus 로고    scopus 로고
    • Interleukin-6 and insulin resistance
    • Kim JH, Bachmann RA, &, Chen J, (2009): Interleukin-6 and insulin resistance. Vitam Horm 80: 613-633.
    • (2009) Vitam Horm , vol.80 , pp. 613-633
    • Kim, J.H.1    Bachmann, R.A.2    Chen, J.3
  • 29
    • 77954096689 scopus 로고    scopus 로고
    • IL-6: Regulator of Treg/Th17 balance
    • Kimura A, &, Kishimoto T, (2010): IL-6: regulator of Treg/Th17 balance. Eur J Immunol 40: 1830-1835.
    • (2010) Eur J Immunol , vol.40 , pp. 1830-1835
    • Kimura, A.1    Kishimoto, T.2
  • 30
    • 79251606719 scopus 로고    scopus 로고
    • Safety and efficacy of ranibizumab in diabetic macular edema (RESOLVE Study): A 12-month, randomized, controlled, double-masked, multicenter phase II study
    • Massin P, Bandello F, Garweg JG, et al., (2010): Safety and efficacy of ranibizumab in diabetic macular edema (RESOLVE Study): a 12-month, randomized, controlled, double-masked, multicenter phase II study. Diabetes Care 33: 2399-2405.
    • (2010) Diabetes Care , vol.33 , pp. 2399-2405
    • Massin, P.1    Bandello, F.2    Garweg, J.G.3
  • 31
    • 79953311138 scopus 로고    scopus 로고
    • The restore study: Ranibizumab monotherapy or combined with laser versus laser monotherapy for diabetic macular edema
    • Mitchell P, Bandello F, Schmidt-Erfurth U, et al., (2011): The restore study: ranibizumab monotherapy or combined with laser versus laser monotherapy for diabetic macular edema. Ophthalmology 118: 615-625.
    • (2011) Ophthalmology , vol.118 , pp. 615-625
    • Mitchell, P.1    Bandello, F.2    Schmidt-Erfurth, U.3
  • 32
    • 33846314712 scopus 로고    scopus 로고
    • Elevated intravitreal interleukin-6 levels in patients with proliferative diabetic retinopathy
    • Mocan MC, Kadayifcilar S, &, Eldem B, (2006): Elevated intravitreal interleukin-6 levels in patients with proliferative diabetic retinopathy. Can J Ophthalmol 41: 747-752.
    • (2006) Can J Ophthalmol , vol.41 , pp. 747-752
    • Mocan, M.C.1    Kadayifcilar, S.2    Eldem, B.3
  • 33
    • 47749107263 scopus 로고    scopus 로고
    • Proinflammatory cytokines and angiogenic and anti-angiogenic factors in vitreous of patients with proliferative diabetic retinopathy and eales' disease
    • Murugeswari P, Shukla D, Rajendran A, Kim R, Namperumalsamy P, &, Muthukkaruppan V, (2008): Proinflammatory cytokines and angiogenic and anti-angiogenic factors in vitreous of patients with proliferative diabetic retinopathy and eales' disease. Retina 28: 817-824.
    • (2008) Retina , vol.28 , pp. 817-824
    • Murugeswari, P.1    Shukla, D.2    Rajendran, A.3    Kim, R.4    Namperumalsamy, P.5    Muthukkaruppan, V.6
  • 34
    • 12444264449 scopus 로고    scopus 로고
    • Increased concentration of pentosidine, an advanced glycation end product, and interleukin-6 in the vitreous of patients with proliferative diabetic retinopathy
    • Nakamura N, Hasegawa G, Obayashi H, et al., (2003): Increased concentration of pentosidine, an advanced glycation end product, and interleukin-6 in the vitreous of patients with proliferative diabetic retinopathy. Diabetes Res Clin Pract 61: 93-101.
    • (2003) Diabetes Res Clin Pract , vol.61 , pp. 93-101
    • Nakamura, N.1    Hasegawa, G.2    Obayashi, H.3
  • 35
    • 77956980190 scopus 로고    scopus 로고
    • Infliximab for diabetic macular edema refractory to laser photocoagulation: A randomized, double-blind, placebo-controlled, crossover, 32-week study
    • Sfikakis PP, Grigoropoulos V, Emfietzoglou I, et al., (2010): Infliximab for diabetic macular edema refractory to laser photocoagulation: a randomized, double-blind, placebo-controlled, crossover, 32-week study. Diabetes Care 33: 1523-1528.
    • (2010) Diabetes Care , vol.33 , pp. 1523-1528
    • Sfikakis, P.P.1    Grigoropoulos, V.2    Emfietzoglou, I.3
  • 36
    • 58449115169 scopus 로고    scopus 로고
    • Multiplex immunoassay analysis of biomarkers in clinically accessible quantities of human aqueous humor
    • Sharma RK, Rogojina AT, &, Chalam KV, (2009): Multiplex immunoassay analysis of biomarkers in clinically accessible quantities of human aqueous humor. Mol Vis 15: 60-69.
    • (2009) Mol Vis , vol.15 , pp. 60-69
    • Sharma, R.K.1    Rogojina, A.T.2    Chalam, K.V.3
  • 37
    • 0033646758 scopus 로고    scopus 로고
    • Clinical factors related to the aqueous levels of vascular endothelial growth factor and hepatocyte growth factor in proliferative diabetic retinopathy
    • Shinoda K, Ishida S, Kawashima S, et al., (2000): Clinical factors related to the aqueous levels of vascular endothelial growth factor and hepatocyte growth factor in proliferative diabetic retinopathy. Curr Eye Res 21: 655-661.
    • (2000) Curr Eye Res , vol.21 , pp. 655-661
    • Shinoda, K.1    Ishida, S.2    Kawashima, S.3
  • 38
    • 79960072567 scopus 로고    scopus 로고
    • Expression profiles of cytokines and chemokines in vitreous fluid in diabetic retinopathy and central retinal vein occlusion
    • Suzuki Y, Nakazawa M, Suzuki K, Yamazaki H, &, Miyagawa Y, (2011): Expression profiles of cytokines and chemokines in vitreous fluid in diabetic retinopathy and central retinal vein occlusion. Jpn J Ophthalmol 55: 256-263.
    • (2011) Jpn J Ophthalmol , vol.55 , pp. 256-263
    • Suzuki, Y.1    Nakazawa, M.2    Suzuki, K.3    Yamazaki, H.4    Miyagawa, Y.5
  • 39
    • 79960190061 scopus 로고    scopus 로고
    • Inflammation in diabetic retinopathy
    • Tang J, &, Kern TS, (2011): Inflammation in diabetic retinopathy. Prog Retin Eye Res 30: 343-358.
    • (2011) Prog Retin Eye Res , vol.30 , pp. 343-358
    • Tang, J.1    Kern, T.S.2
  • 42
    • 77949537099 scopus 로고    scopus 로고
    • Comprehensive analysis of inflammatory immune mediators in vitreoretinal diseases
    • Yoshimura T, Sonoda KH, Sugahara M, et al., (2009): Comprehensive analysis of inflammatory immune mediators in vitreoretinal diseases. PLoS One 4: e8158.
    • (2009) PLoS One , vol.4
    • Yoshimura, T.1    Sonoda, K.H.2    Sugahara, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.