The effect of synthetic c-reactive protein on the in vitro immune response of human pbmcs stimulated with bacterial reagents

Inflammation

Volumn 36, Issue 4, 2013, Pages 781-792

  Sato, Atsushi ^a   Nakashima, Hiroyuki ^a   Kinoshita, Manabu ^a   Nakashima, Masahiro ^a   Ogawa, Yoshiko ^a   Shono, Satoshi ^a   Ikarashi, Masami ^a   Seki, Shuhji ^a  

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

Author keywords

C reactive protein; high mobility group box 1; human PBMCs; inflammation; tumor necrosis factor

Indexed keywords

BACTERIAL DNA; C REACTIVE PROTEIN; CD56 ANTIGEN; CPG OLIGODEOXYNUCLEOTIDE; GAMMA INTERFERON; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PENICILLIN DERIVATIVE; PICIBANIL; PROTEIN P40; PROTEIN P70; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL MOTILITY; CYTOKINE PRODUCTION; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME REGULATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOMODULATION; IN VITRO STUDY; MACROPHAGE; NATURAL KILLER CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; SEPTIC SHOCK; STREPTOCOCCUS PYOGENES;

ANIMALS; C-REACTIVE PROTEIN; DNA, BACTERIAL; HMGB1 PROTEIN; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-12; KILLER CELLS, NATURAL; KUPFFER CELLS; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; PERFORIN; RECOMBINANT PROTEINS; SHOCK, SEPTIC; SHWARTZMAN PHENOMENON; STREPTOCOCCUS PYOGENES; TUMOR NECROSIS FACTOR-ALPHA;

BACTERIA (MICROORGANISMS); MUS; STREPTOCOCCUS PYOGENES;

EID: 84880295179     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-013-9604-4     Document Type: Article

References (35)

1. Volanakis, J.E. 2001. Human C-reactive protein: expression, structure, and function. Molecular Immunology 38: 189-197.
2. Du Clos, T.W. 2000. Function of C-reactive protein. Annals of Medicine 32: 274-278.
3. Barna, B.P.; M.J. Thomassen, M. Maier, S.V. Medendorp, R.R. Tubbs, T. Chiang, P. Zhou, B. Yen-Lieberman, S. Singh-Burgess, and S.D. Deodhar. 1994. Combination therapy with a synthetic peptide of C-reactive protein and interleukin 2: augmented survival and eradication of pulmonary metastases. Cancer Immunology, Immunotherapy 38: 38-42.
4. Zhong, W.; Q. Zen, J. Tebo, K. Schlottmann, M. Coggeshall, and R.F. Mortensen. 1998. Effect of human C-reactive protein on chemokine and chemotactic factor-induced neutrophil chemotaxis and signaling. Journal of Immunology 161: 2533-2540.
5. Inatsu, A.; M. Kinoshita, H. Nakashima, J. Shimizu, D. Saitoh, S. Tamai, and S. Seki. 2009. Novel mechanism of C-reactive protein for enhancing mouse liver innate immunity. Hepatology 49: 2044-2054.
6. Motegi, A.; M. Kinoshita, K. Sato, N. Shinomiya, S. Ono, S. Nonoyama, H. Hiraide, and S. Seki. 2006. An in vitro Shwartzman reaction-like response is augmented age-dependently in human peripheral blood mononuclear cells. Journal of Leukocyte Biology 79: 463-472.
7. Kawabata, T.; M. Kinoshita, A. Inatsu, Y. Habu, H. Nakashima, N. Shinomiya, and S. Seki. 2008. Functional alterations of liver innate immunity of mice with aging in response to CpG-oligodeoxynucleotide. Hepatology 48: 1586-1597.
8. Seki, S.; Y. Habu, T. Kawamura, K. Takeda, H. Dobashi, T. Ohkawa, and H. Hiraide. 2000. The liver as a crucial organ in the first line of host defense: the roles of Kupffer cells, natural killer (NK) cells and NK1.1 Ag+ T cells in T helper 1 immune responses. Immunology Reviews 174: 35-46.
9. Seki, S.; H. Nakashima, and M. Kinoshita. 2012. The liver as a pivotal innate immune organ. Immuno-Gastroenterology 1: 76-89.
10. Lopez-Verges, S.; J.M. Milush, S. Pandey, V.A. York, J. Arakawa-Hoyt, H. Pircher, P.J. Norris, D.F. Nixon, and L.L. Lanier. 2010. CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset. Blood 116: 3865-3874.
11. Kawarabayashi, N.; S. Seki, K. Hatsuse, T. Ohkawa, Y. Koike, T. Aihara, Y. Habu, R. Nakagawa, K. Ami, H. Hiraide, and H. Mochizuki. 2000. Decrease of CD56(+)T cells and natural killer cells in cirrhotic livers with hepatitis C may be involved in their susceptibility to hepatocellular carcinoma. Hepatology 32: 962-969.
12. Seki, S.; H. Nakashima, M. Nakashima, and M. Kinoshita. 2011. Antitumor immunity produced by the liver Kupffer cells, NK cells, NKT cells, and CD8 CD122 T cells. Clinical & Developmental Immunology: 868345.
13. Ozmen, L.; M. Pericin, J. Hakimi, R.A. Chizzonite, M. Wysocka, G. Trinchieri, M. Gately, and G. Garotta. 1994. Interleukin 12, interferon gamma, and tumor necrosis factor alpha are the key cytokines of the generalized Shwartzman reaction. The Journal of Experimental Medicine 180: 907-915.
14. Sato, K.; M. Kinoshita, A. Motegi, Y. Habu, E. Takayama, S. Nonoyama, H. Hiraide, and S. Seki. 2005. Critical role of the liver CD8+ CD122+ T cells in the generalized Shwartzman reaction of mice. European Journal of Immunology 35: 593-602.
15. Shono, S.; Y. Habu, M. Nakashima, A. Sato, H. Nakashima, H. Miyazaki, M. Kinoshita, G. Tsumatori, N. Shinomiya, and S. Seki. 2011. The immunologic outcome of enhanced function of mouse liver lymphocytes and kupffer cells by high-fat and high-cholesterol diet. Shock 36: 484-493.
16. Kokkola, R.; A. Andersson, G. Mullins, T. Ostberg, C.J. Treutiger, B. Arnold, P. Nawroth, U. Andersson, R.A. Harris, and H.E. Harris. 2005. RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages. Scandinavian Journal of Immunology 61: 1-9.
17. Wang, H.; O. Bloom, M. Zhang, J.M. Vishnubhakat, M. Ombrellino, J. Che, A. Frazier, H. Yang, S. Ivanova, L. Borovikova, K.R. Manogue, E. Faist, E. Abraham, J. Andersson, U. Andersson, P.E. Molina, N.N. Abumrad, A. Sama, and K.J. Tracey. 1999. HMG-1 as a late mediator of endotoxin lethality in mice. Science 285: 248-251.
18. Yanai, H.; T. Ban, Z. Wang, M.K. Choi, T. Kawamura, H. Negishi, M. Nakasato, Y. Lu, S. Hangai, R. Koshiba, D. Savitsky, L. Ronfani, S. Akira, M.E. Bianchi, K. Honda, T. Tamura, T. Kodama, and T. Taniguchi. 2009. HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses. Nature 462: 99-103.
19. Medzhitov, R.; and C.A. Janeway Jr. 1997. Innate immunity: the virtues of a nonclonal system of recognition. Cell 91: 295-298.
20. Buttenschoen, K.; D.C. Buttenschoen, D. Berger, C. Vasilescu, S. Schafheutle, B. Goeltenboth, M. Seidelmann, and H.G. Beger. 2001. Endotoxemia and acute-phase proteins in major abdominal surgery. American Journal of Surgery 181: 36-43.
21. Tschaikowsky, K.; M. Hedwig-Geissing, J. Schmidt, and G.G. Braun. 2011. Lipopolysaccharide-binding protein for monitoring of postoperative sepsis: complemental to C-reactive protein or redundant? PLoS One 6: e23615.
22. Mold, C.; W. Rodriguez, B. Rodic-Polic, and T.W. Du Clos. 2002. C-reactive protein mediates protection from lipopolysaccharide through interactions with Fc gamma R. Journal of Immunology 169: 7019-7025.
23. Bodman-Smith, K.B.; R.E. Gregory, P.T. Harrison, and J.G. Raynes. 2004. FcgammaRIIa expression with FcgammaRI results in C-reactive protein- and IgG-mediated phagocytosis. Journal of Leukocyte Biology 75: 1029-1035.
24. Baum, L.L.; K.K. James, R.R. Glaviano, and H. Gewurz. 1983. Possible role for C-reactive protein in the human natural killer cell response. The Journal of Experimental Medicine 157: 301-311.
25. Tateishi, Y.; S. Oda, M. Nakamura, K. Watanabe, T. Kuwaki, T. Moriguchi, and H. Hirasawa. 2007. Depressed heart rate variability is associated with high IL-6 blood level and decline in the blood pressure in septic patients. Shock 28: 549-553.
26. Gabay, C.; and I. Kushner. 1999. Acute-phase proteins and other systemic responses to inflammation. The New England Journal of Medicine 340: 448-454.
27. Hiraki, S.; S. Ono, M. Kinoshita, H. Tsujimoto, S. Seki, and H. Mochizuki. 2007. Interleukin-18 restores immune suppression in patients with nonseptic surgery, but not with sepsis. American Journal of Surgery 193: 676-680.
28. Kinoshita, M.; T. Uchida, A. Sato, M. Nakashima, H. Nakashima, S. Shono, Y. Habu, H. Miyazaki, S. Hiroi, and S. Seki. 2010. Characterization of two F4/80-positive Kupffer cell subsets by their function and phenotype in mice. Journal of Hepatology 53: 903-910.
29. Szalai, A.J.; D.E. Briles, and J.E. Volanakis. 1995. Human C-reactive protein is protective against fatal Streptococcus pneumoniae infection in transgenic mice. Journal of Immunology 155: 2557-2563.
30. Xia, D.; and D. Samols. 1997. Transgenic mice expressing rabbit C-reactive protein are resistant to endotoxemia. Proceedings of the National Academy of Sciences of the United States of America 94: 2575-2580.
31. Szalai, A.J.; J.L. VanCott, J.R. McGhee, J.E. Volanakis, and W.H. Benjamin Jr. 2000. Human C-reactive protein is protective against fatal Salmonella enterica serovar typhimurium infection in transgenic mice. Infection and Immunity 68: 5652-5656.
32. Coussens, L.M.; and Z. Werb. 2002. Inflammation and cancer. Nature 420: 860-867.
33. Allin, K.H.; and B.G. Nordestgaard. 2011. Elevated C-reactive protein in the diagnosis, prognosis, and cause of cancer. Critical Reviews in Clinical Laboratory Sciences 48: 155-170.
34. Woo, Y.; W.J. Hyung, K. Obama, H.I. Kim, K.H. Pak, T. Son, and S.H. Noh. 2012. Elevated high-sensitivity C-reactive protein, a marker of advanced stage gastric cancer and postgastrectomy disease recurrence. Journal of Surgical Oncology 105: 405-409.
35. Zacho, J.; A. Tybjaerg-Hansen, J.S. Jensen, P. Grande, H. Sillesen, and B.G. Nordestgaard. 2008. Genetically elevated C-reactive protein and ischemic vascular disease. The New England Journal of Medicine 359: 1897-1908.