Decrease of CD56+T cells and natural killer cells in cirrhotic livers with hepatitis C may be involved in their susceptibility to hepatocellular carcinoma

Hepatology

Volumn 32, Issue 5, 2000, Pages 962-969

  Kawarabayashi, Nobuaki ^a   Seki, Shuhji ^a   Hatsuse, Kazuo ^a   Ohkawa, Takashi ^a   Koike, Yuji ^a   Aihara, Tsukasa ^a   Habu, Yoshiko ^a   Nakagawa, Ryusuke ^a   Ami, Katsunori ^a   Hiraide, Hoshio ^a   Mochizuki, Hidetaka ^a  

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD56 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 2;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; CYTOTOXICITY; FLOW CYTOMETRY; HEPATITIS C; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL CARCINOMA; LIVER CELL CULTURE; LIVER CIRRHOSIS; MONONUCLEAR CELL; NATURAL KILLER CELL; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

EID: 0033759170     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2000.19362     Document Type: Article

References (46)

1. Hepatitis C
2. Isolation, phenotyping, and functional analysis of lymphocytes from human liver
3. T-lymphocyte response to hepatitis C virus in different clinical courses of infection
4. +T cells specific for the protein NS4 of hepatitis C virus in patients with chronic hepatitis C
5. Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes recognize epitopes in the core and envelope proteins of HCV
6. HLA B44-restricted cytotoxic T lymphocytes recognizing an epitope on hepatitis C virus nucleocapsid protein
7. Immunoregulatory cytokines in chronic hepatitis C virus infection: Pre- and posttreatment with interferon alfa
8. Progressive liver injury in chronic hepatitis C infection correlates with increased intrahepatic expression of Thl-associated cytokines
9. + cells in the liver of mice
10. + αβ T cells with intermediate TCR induced in the liver of mice by IL-12
11. + αβ T cells as a major effector in inhibition of tumor metastasis
12. Mouse liver T cells: Their change with aging and in comparison with peripheral T cells
13. Cytotoxic γδ or αβ T cells with an NK cell marker, CD56, induced from human peripheral blood lymphocytes by the combination of IL-12 and IL-2
14. +T cells on experimental hematogenous tumor metastasis in the liver and lung
15. +T cells in IL-12-mediated rejection of tumors
16. +T cells in T helper 1 immune responses
17. +T cells and their IFN-γ production in the generalized Shwartzman reaction
18. Hormonal control of α-fetoprotein secretion in human hepatoma cell lines proliferating in chemically defined medium
19. Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes
20. A potential role for interleukin-15 in the regulation of human natural killer cell survival
21. Long-incubation post-transfusion hepatitis without serological evidence of exposure to hepatitis-B virus
22. Transfusion-associated hepatitis not due to viral hepatitis type A or B
23. Posttransfusion non-A, non-B hepatitis in chimpanzees. Physicochemical evidence that the tubule-forming agent is a small, enveloped virus
24. Cloning of a cDNA associated with acute and chronic hepatitis C infection generated from patients serum RNA
25. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
26. +T cells
27. Supportive cellular elements for hepatic T cell differentiation: T cells expressing intermediate levels of the T cell receptor are cytotoxic against syngeneic hepatoma, and are lost after hepatocyte damage
28. A comparison of proliferative response to IL-7 and expression of IL-7 receptors in intermediate TCR cells of the liver, spleen, and thymus
29. + stem cells and thymocyte precursors in the livers of adult mice
30. Presence of hematopoietic stem cells in the adult liver
31. RAG1, RAG2 and pre-T cell receptor alpha chain expression by adult human hepatic T cells: Evidence for extrathymic T cell maturation
32. In vitro evidence for the presence of hematopoietic stem cells in the adult human liver
33. + CTLs in vivo
34. Exacerbated viral hepatitis in IFN-γ receptor-deficient mice is not suppressed by IL-12
35. Extrathymic differentiation of a T cell bearing invariant V alpha 14J alpha 281 TCR
36. -8- T cells in mice and humans
37. CD1d-restricted and TCR-mediated activation of v-alpha14 NKT cells by glycosylceramides
38. CD1d-mediated recognition of an alpha-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution
39. CD1d-restricted recognition of synthetic glycolipid antigens by human natural killer T cells
40. Innate and adaptive lymphoid cells in the human liver
41. + αβ T cells with potent cytotoxicity in the liver of mice via production of IL-12 from Kupffer cells
42. +T cells by bacterial super-antigen primed Kupffer cells
43. Interleukin 12: A proinflammatory cytokine with immunomodulatory functions that bridge innate resistance and antigen-specific adaptive immunity
44. YAC-1 MHC class I variants reveal an association between decreased NK sensitivity and increased H-2 expression after interferon treatment or in vivo passage
45. NK susceptibility varies inversely with target cell class I HLA antigen expression
46. Analysis of mechanisms by which NK cells acquire increased cytotoxicity against class I MHC-eliminated targets