Acetylation of retinoblastoma like protein2 (Rb2/p130) in tumor tissues

Asian Pacific Journal of Cancer Prevention

Volumn 14, Issue 4, 2013, Pages 2255-2258

  Khan, Z N ^a   Sabir, M ^a   Kayani, M A ^a   Saeed, M ^a  

^a Department of Electrical Computer Engineering   (Pakistan)

Author keywords

Acetylation; Cell cycle; Pocket proteins; Protein modification; Rb2 p130

Indexed keywords

EID: 84880286001     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2013.14.3.2255     Document Type: Article

References (19)

1. Baldi A, Esposito V, De Luca A, et al (1996b). Differential expression of the retinoblastoma gene family members pRb/ p105, p107, and pRb2/p130 in lung cancer. Clin Cancer Res, 2, 1239-45.
2. Bosco EE, Knudsen ES (2007). RB in breast cancer: at the crossroads of tumor genesis and treatment. Cell Cycle, 6, 667-71.
3. Classon M, Dyson D (2001). P107 and p130: versatile proteins with interesting pockets. Exp Cell Res, 264, 135-47.
4. Classon M, Harlow E (2002). The retinoblastoma tumor suppressor in development and cancer. Nat Rev Cancer, 2, 910-7.
5. Claudio PP, Howard CM, Baldi A, et al (1994). p130/pRb2 has growth suppressive properties similar to yet distinctive from those of retinoblastoma family members pRb and p107. Cancer Res, 54, 5556-60.
6. Claudio PP, Tonini T, Giordano A (2002). The retinoblastoma family: twins or distant cousins?. Genome Biol, 3, 1-9.
7. Cobrinik D (2005). Pocket proteins and cell cycle control. Oncogene, 24, 2796-809.
8. Giacinti C, Giordano A (2006). Rb and cell cycle progression. Oncogene, 25, 5220-7.
9. Knudsen ES, Knudsen KE (2008). Tailoring to RB: tumor suppressor status and therapeutics response. Nat Rev Cancer, 8, 714-24.
10. Korenjak M, Brehm A (2005). E2F-Rb complexes regulating transcription of genes important for differentiation and development. Curr Opin Genet Dev, 15, 520-7.
11. Lacy S, Whyte P (1997). Identification of a p130 domain mediating interactions with cyclin A/cdk 2 and cyclin E/ cdk 2 complexes. Oncogene, 14, 2395-406.
12. Longworth MS, Dyson NJ (2010).pRb, a local chromatin organizer with global possibilities. Chromosoma, 119, 1-11.
13. Nguyen DX, Baglia LA, Huang SM, Baker CM, McCance DJ (2004). Acetylation Regulates the Differentiation- Specific Functions of the retinoblastoma protein. EMBO, 23, 1609- 18.
14. Paggi MG, Giordano A (2001). Who is the boss in the retinoblastoma family? The point of view of Rb2/p130, the little brother. Cancer Res, 61, 4651-4.
15. Rocha-Sanchez SMS, Beisel KW (2007). Pocket proteins and cell cycle regulation in inner ear development. Int J Dev Biol, 51, 585-95.
16. Saeed M, Schwarze F, Loidl A, et al (2012).In vitro phosphorylation and acetylation of the murine pocket protein Rb2/p130. PLoS ONE, 7, 46174.
17. Schwarze F, Meraner J, Lechner M, et al (2010). Cell cycledependent acetylation of Rb2/p130 in NIH3T3 cells. Oncogene, 29, 5755-60.
18. Smith EJ, Leone G, DeGregori J, et al (1996). The accumulation of an E2F-p130 transcriptional repressor distinguishes a Go cell state from G1 cell state. Mol Cell Biol, 16, 6965-76.
19. Toppari J, Suominenf JS, Yan W (2003). The role of retinoblastoma protein family in the control of germ cell proliferation, differentiation and survival. APMIS, 111, 245-51