The cannabinoid receptor type 1 is essential for mesenchymal stem cell survival and differentiation: Implications for bone health

Stem Cells International

Volumn , Issue , 2013, Pages

  Gowran, Aoife ^a   McKayed, Katey ^a   Campbell, Veronica A ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; CANNABINOID 1 RECEPTOR; CASPASE 3; DEXAMETHASONE; DRONABINOL; ENDOCANNABINOID; GLYCEROL 2 PHOSPHATE; HYDROXYAPATITE; MESSENGER RNA; RIMONABANT;

ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; BONE METABOLISM; BONE REGENERATION; CELL DIFFERENTIATION; CELL STRESS; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; MESENCHYMAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; TISSUE ENGINEERING;

EID: 84880276352     PISSN: None     EISSN: 16879678     Source Type: Journal    
DOI: 10.1155/2013/796715     Document Type: Article

References (38)

1. Pittenger M. F., Mesenchymal stem cells from adult bone marrow. Methods in Molecular Biology 2008 449 27 44 2-s2.0-44649126719 10.1007/978-1-60327-169- 1-2
2. Caplan A. I., Adult mesenchymal stem cells for tissue engineering versus regenerative medicine. Journal of Cellular Physiology 2007 213 2 341 347 2-s2.0-34848863384 10.1002/jcp.21200 (Pubitemid 47509711)
3. Mauney J. R., Volloch V., Kaplan D. L., Role of adult mesenchymal stem cells in bone tissue-engineering applications: current status and future prospects. Tissue Engineering 2005 11 5-6 787 802 2-s2.0-20444454865 10.1089/ten.2005.11.787 (Pubitemid 40960782)
4. Farrell E., O'Brien F. J., Doyle P., Fischer J., Yannas I., Harley B. A., O'Connell B., Prendergast P. J., Campbell V. A., A collagen-glycosaminoglycan scaffold supports adult rat mesenchymal stem cell differentiation along osteogenic and chondrogenic routes. Tissue Engineering 2006 12 3 459 468 2-s2.0-33646375175 (Pubitemid 43673451)
5. Kanichai M., Ferguson D., Prendergast P. J., Campbell V. A., Hypoxia promotes chondrogenesis in rat mesenchymal stem cells: a role for AKT and hypoxia-inducible factor (HIF)-1 α Journal of Cellular Physiology 2008 216 3 708 715 2-s2.0-48749086529 10.1002/jcp.21446
6. McMahon L. A., Prendergast P. J., Campbell V. A., A comparison of the involvement of p38, ERK1/2 and PI3K in growth factor-induced chondrogenic differentiation of mesenchymal stem cells. Biochemical and Biophysical Research Communications 2008 368 4 990 995 2-s2.0-40049101000 10.1016/j.bbrc.2008.01.160
7. Kumar R. N., Chambers W. A., Pertwee R. G., Pharmacological actions and therapeutic uses of cannabis and cannabinoids. Anaesthesia 2001 56 11 1059 1068 2-s2.0-0034766553 10.1046/j.1365-2044.2001.02269.x (Pubitemid 33039932)
8. Salazar M., Carracedo A., Salanueva Í. J., Hernández-Tiedra S., Lorente M., Egia A., Vázquez P., Blázquez C., Torres S., García S., Nowak J., Fimia G. M., Piacentini M., Cecconi F., Pandolfi P. P., González-Feria L., Iovanna J. L., Guzmán M., Boya P., Velasco G., Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. Journal of Clinical Investigation 2009 119 5 1359 1372 2-s2.0-66449115318 10.1172/JCI37948
9. Gowran A., Campbell V. A., A role for p53 in the regulation of lysosomal permeability by delta 9-tetrahydrocannabinol in rat cortical neurones: implications for neurodegeneration. Journal of Neurochemistry 2008 105 1513 1524 (Pubitemid 351590812)
10. Greenhough A., Patsos H. A., Williams A. C., Paraskeva C., The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells. International Journal of Cancer 2007 121 2172 2180 (Pubitemid 47585595)
11. Caffarel M. M., Sarrio D., Palacios J., Guzman M., Sanchez C., Delta9-tetrahydrocannabinol inhibits cell cycle progression in human breast cancer cells through Cdc2 regulation. Cancer Research 2006 66 6615 6621 (Pubitemid 44085617)
12. Howlett A. C., Barth F., Bonner T. I., Cabral G., Casellas P., Devane W. A., Felder C. C., Herkenham M., Mackie K., Martin B. R., Mechoulam R., Pertwee R. G., International union of pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacological Reviews 2002 54 161 202 (Pubitemid 34575709)
13. Idris A. I., van't Hof R. J., Greig I. R., Ridge S. A., Baker D., Ross R. A., Ralston S. H., Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors. Nature Medicine 2005 11 774 779 (Pubitemid 41021210)
14. Idris A. I., Sophocleous A., Landao-Bassonga E., Canals M., Milligan G., Baker D., van't Hof R. J., Ralston S. H., Cannabinoid receptor type 1 protects against age- related osteoporosis by regulating osteoblast and adipocyte differentiation in marrow stromal cells. Cell Metabolism 2009 10 2 139 147 2-s2.0-67849129193 10.1016/j.cmet.2009.07.006
15. Ofek O., Karsak M., Leclerc N., Fogel M., Frenkel B., Wright K., Tam J., Attar-Namdar M., Kram V., Shohami E., Mechoulam R., Zimmer A., Bab I., Peripheral cannabinoid receptor, CB2, regulates bone mass. Proceedings of the National Academy of Sciences of the United States of America 2006 103 3 696 701 2-s2.0-31444437185 10.1073/pnas.0504187103 (Pubitemid 43153088)
16. Scutt A., Williamson E. M., Cannabinoids stimulate fibroblastic colony formation by bone marrow cells indirectly via CB2 receptors. Calcified Tissue International 2007 80 1 50 59 2-s2.0-33846223892 10.1007/s00223-006-0171-7 (Pubitemid 46098877)
17. Idris A. I., Sophocleous A., Landao-Bassonga E., Van't Hof R. J., Ralston S. H., Regulation of bone mass, osteoclast function, and ovariectomy-induced bone loss by the type 2 cannabinoid receptor. Endocrinology 2008 149 11 5619 5626 2-s2.0-54349124546 10.1210/en.2008-0150
18. Pittenger M. F., Mackay A. M., Beck S. C., Jaiswal R. K., Douglas R., Mosca J. D., Moorman M. A., Simonetti D. W., Craig S., Marshak D. R., Multilineage potential of adult human mesenchymal stem cells. Science 1999 284 5411 143 147 2-s2.0-0033515827 10.1126/science.284.5411.143 (Pubitemid 29282067)
19. Kraus K. H., Kirker-Head C., Mesenchymal stem cells and bone regeneration. Veterinary Surgery 2006 35 3 232 242 2-s2.0-33645518250 10.1111/j.1532-950X.2006.00142.x
20. Bruder S. P., Fox B. S., Tissue engineering of bone: cell based strategies. Clinical Orthopaedics and Related Research 1999 367 S68 S83 2-s2.0-0032758946 (Pubitemid 29501488)
21. Meijer G. J., De Bruijn J. D., Koole R., Van Blitterswijk C. A., Cell-based bone tissue engineering. PLoS Medicine 2007 4 2 260 264 2-s2.0-33847654340 10.1371/journal.pmed.0040009 (Pubitemid 46354438)
22. Slater B. J., Kwan M. D., Gupta D. M., Panetta N. J., Longaker M. T., Mesenchymal cells for skeletal tissue engineering. Expert Opinion on Biological Therapy 2008 8 7 885 893 2-s2.0-47549116418 10.1517/14712598.8.7.885 (Pubitemid 352007001)
23. Idris A. I., Ralston S. H., Cannabinoids and bone: friend or foe? Calcified Tissue International 2010 87 4 285 297 2-s2.0-77957693795 10.1007/s00223-010-9378-8
24. Whyte L. S., Ryberg E., Sims N. A., Ridge S. A., Mackie K., Greasley P. J., Ross R. A., Rogers M. J., The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo. Proceedings of the National Academy of Sciences of the United States of America 2009 106 38 16511 16516 2-s2.0-70349510641 10.1073/pnas.0902743106
25. Carter D. R., Beaupré G. S., Giori N. J., Helms J. A., Mechanobiology of skeletal regeneration. Clinical Orthopaedics and Related Research 1998 355 S41 S55 2-s2.0-0031788127
26. Van Der Stelt M., Di Marzo V., Cannabinoid receptors and their role in neuroprotection. NeuroMolecular Medicine 2005 7 1-2 37 50 2-s2.0-24644450190 (Pubitemid 41278188)
27. Lamontagne D., Lépicier P., Lagneux C., Bouchard J. F., The endogenous cardiac cannabinoid system: a new protective mechanism against myocardial ischemia. Archives des Maladies du Coeur et des Vaisseaux 2006 99 3 242 246 2-s2.0-33646181593 (Pubitemid 46211438)
28. Cudaback E., Marrs W., Moeller T., Stella N., The expression level of CB1 and CB2 receptors determines their efficacy at inducing apoptosis in astrocytomas. PLoS ONE 2010 5 1 2-s2.0-77952532122 10.1371/journal.pone.0008702 e8702
29. Gowran A., McKayed K., Kanichai M., White C., Hammadi N., Campbell V., Tissue engineering of cartilage; can cannabinoids help? Pharmaceuticals 2010 3 9 2970 2985 2-s2.0-77957265395 10.3390/ph3092970
30. Lozano-Ondoua A. N., Wright C., Vardanyan A., King T., Largent-Milnes T. M., Nelson M., Jimenez-Andrade J. M., Mantyh P. W., Vanderah T. W., A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss. Life Sciences 2010 86 17-18 646 653 2-s2.0-77951238358 10.1016/j.lfs.2010.02.014
31. Randall M. D., Kendall D. A., Bennett A. J., O'Sullivan S. E., Rimonabant in obese patients with type 2 diabetes. The Lancet 2007 369 9561, article 555 2-s2.0-33846939252 10.1016/S0140-6736(07)60265-7 (Pubitemid 46241434)
32. Nogueira-Filho G. D. R., Cadide T., Rosa B. T., Neiva T. G., Tunes R., Peruzzo D., Nociti F. H. Jr., César-Neto J. B., Cannabis sativa smoke inhalation decreases bone filling around titanium implants: a histomorphometric study in rats. Implant Dentistry 2008 17 4 461 470 2-s2.0-58149345834 10.1097/ID.0b013e31818c5a2a
33. Napimoga M. H., Benatti B. B., Lima F. O., Alves P. M., Campos A. C., Pena-dos-Santos D. R., Severino F. P., Cunha F. Q., Guimarães F. S., Cannabidiol decreases bone resorption by inhibiting RANK/RANKL expression and pro-inflammatory cytokines during experimental periodontitis in rats. International Immunopharmacology 2009 9 2 216 222 2-s2.0-58249144544 10.1016/j.intimp.2008.11.010
34. Athanasiou A., Clarke A. B., Turner A. E., Kumaran N. M., Vakilpour S., Smith P. A., Bagiokou D., Bradshaw T. D., Westwell A. D., Fang L., Lobo D. N., Constantinescu C. S., Calabrese V., Loesch A., Alexander S. P. H., Clothier R. H., Kendall D. A., Bates T. E., Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and Biophysical Research Communications 2007 364 1 131 137 2-s2.0-35348942818 10.1016/j.bbrc.2007.09.107 (Pubitemid 47610668)
35. Pietilä M., Lehtonen S., Närhi M., Hassinen I. E., Leskelä H.-V., Aranko K., Nordström K., Vepsäläinen A., Lehenkari P., Mitochondrial function determines the viability and osteogenic potency of human mesenchymal stem cells. Tissue Engineering C 2010 16 3 435 445 2-s2.0-77952901279 10.1089/ten.tec.2009.0247
36. Fini M., Giavaresi G., Salamanna F., Veronesi F., Martini L., De Mattei M., Tschon M., Harmful lifestyles on orthopedic implantation surgery: a descriptive review on alcohol and tobacco use. Journal of Bone and Mineral Metabolism 2011 29 6 633 644 2-s2.0-83055194470 10.1007/s00774-011-0309-1
37. Hahn J.-Y., Cho H.-J., Kang H.-J., Kim T.-S., Kim M.-H., Chung J.-H., Bae J.-W., Oh B.-H., Park Y.-B., Kim H.-S., Pre-treatment of mesenchymal stem cells with a combination of growth factors enhances gap junction formation, cytoprotective effect on cardiomyocytes, and therapeutic efficacy for myocardial infarction. Journal of the American College of Cardiology 2008 51 9 933 943 2-s2.0-39549105786 10.1016/j.jacc.2007.11.040 (Pubitemid 351282455)
38. Waterman R. S., Tomchuck S. L., Henkle S. L., Betancourt A. M., A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an immunosuppressive MSC2 phenotype. PLoS ONE 2010 5 4 2-s2.0-77956420421 10.1371/journal.pone.0010088 e10088