Asymmetric synthesis and molecular docking study of enantiomerically pure pyrrolidine derivatives with potential antithrombin activity

Tetrahedron Asymmetry

Volumn 24, Issue 13-14, 2013, Pages 838-843

  Ayan, Seylan ^a   Dogan, Özdemir ^a   Ivantcova, Polina M ^b   Datsuk, Nikita G ^b   Shulga, Dmitry A ^b   Chupakhin, Vladimir I ^b   Zabolotnev, Dmitry V ^b   Kudryavtsev, Konstantin V ^b,c  

^a MIDDLE EAST TECHNICAL UNIVERSITY   (Turkey)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

^c INSTITUTE OF PHYSIOLOGICALLY ACTIVE COMPOUNDS   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

4 (TERT BUTYL) 2 METHYL 5 ( 4 BROMOPHENYL) 1 ( 2 (( 4 CHLOROPHENYL)THIO)ACETYL)PYRROLIDINE 2,4 DICARBOXYLIC ACID; 4 (TERT BUTYL) 2 METHYL 5 ( 4 BROMOPHENYL)PYRROLIDINE 2,4 DICARBOXYLIC ACID; FAM LIGAND; LIGAND; PYRROLIDINE DERIVATIVE; THROMBIN INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; ASYMMETRIC SYNTHESIS; BLOOD CLOT LYSIS; CATALYSIS; CHIRALITY; DRUG CONFORMATION; DRUG POTENCY; ENANTIOMER; MOLECULAR DOCKING; PRIORITY JOURNAL;

EID: 84880273093     PISSN: 09574166     EISSN: 1362511X     Source Type: Journal    
DOI: 10.1016/j.tetasy.2013.05.023     Document Type: Article

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