메뉴 건너뛰기




Volumn 386, Issue 8, 2013, Pages 747-755

Vitexin protects against cardiac hypertrophy via inhibiting calcineurin and CaMKII signaling pathways

Author keywords

Calcineurin; CaMKII; Cardiac hypertrophy; NFAT; Vitexin

Indexed keywords

CALCINEURIN; CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; ISOPRENALINE; VITEXIN; APIGENIN; CALCINEURIN INHIBITOR; CARDIOTONIC AGENT;

EID: 84880263683     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-013-0873-0     Document Type: Article
Times cited : (42)

References (46)
  • 1
    • 15244345086 scopus 로고    scopus 로고
    • Calmodulin kinase signaling in heart: An intriguing candidate target for therapy of myocardial dysfunction and arrhythmias
    • 15781121 10.1016/j.pharmthera.2004.11.002 1:CAS:528:DC%2BD2MXisFGlsLo%3D
    • Anderson ME (2005) Calmodulin kinase signaling in heart: an intriguing candidate target for therapy of myocardial dysfunction and arrhythmias. Pharmacol Ther 106:39-55
    • (2005) Pharmacol Ther , vol.106 , pp. 39-55
    • Anderson, M.E.1
  • 2
    • 79960044552 scopus 로고    scopus 로고
    • CaMKII in myocardial hypertrophy and heart failure
    • 21276796 10.1016/j.yjmcc.2011.01.012 1:CAS:528:DC%2BC3MXhtFymt7rN
    • Anderson ME, Brown JH, Bers DM (2011a) CaMKII in myocardial hypertrophy and heart failure. J Mol Cell Cardiol 51:468-473
    • (2011) J Mol Cell Cardiol , vol.51 , pp. 468-473
    • Anderson, M.E.1    Brown, J.H.2    Bers, D.M.3
  • 3
    • 79960044552 scopus 로고    scopus 로고
    • CaMKII in myocardial hypertrophy and heart failure
    • 21276796 10.1016/j.yjmcc.2011.01.012 1:CAS:528:DC%2BC3MXhtFymt7rN
    • Anderson ME, Brown JH, Bers DM (2011b) CaMKII in myocardial hypertrophy and heart failure. J Mol Cell Cardiol 51:468-473
    • (2011) J Mol Cell Cardiol , vol.51 , pp. 468-473
    • Anderson, M.E.1    Brown, J.H.2    Bers, D.M.3
  • 4
    • 84880268432 scopus 로고    scopus 로고
    • Cardiac hypertrophy and calcium signaling
    • 15775536 1:STN:280:DC%2BD2M7kt1eisw%3D%3D
    • Asakawa M, Komuro I (2001) Cardiac hypertrophy and calcium signaling. Clin Calcium 11:424-428
    • (2001) Clin Calcium , vol.11 , pp. 424-428
    • Asakawa, M.1    Komuro, I.2
  • 6
    • 78650121847 scopus 로고    scopus 로고
    • Molecular distinction between physiological and pathological cardiac hypertrophy: Experimental findings and therapeutic strategies
    • 20438756 10.1016/j.pharmthera.2010.04.005 1:CAS:528:DC%2BC3cXhtFGjtrrL
    • Bernardo BC, Weeks KL, Pretorius L, McMullen JR (2010) Molecular distinction between physiological and pathological cardiac hypertrophy: experimental findings and therapeutic strategies. Pharmacol Ther 128:191-227
    • (2010) Pharmacol Ther , vol.128 , pp. 191-227
    • Bernardo, B.C.1    Weeks, K.L.2    Pretorius, L.3    McMullen, J.R.4
  • 8
    • 33745236125 scopus 로고    scopus 로고
    • NADPH oxidasederived reactive oxygen species in cardiac pathophysiology
    • 16321803 10.1098/rstb.2005.1772 1:CAS:528:DC%2BD28Xps1aktA%3D%3D
    • Cave A, Grieve D, Johar S, Zhang M, Shah AM (2005) NADPH oxidasederived reactive oxygen species in cardiac pathophysiology. Philos Trans R Soc Lond, B, Biol Sci 360:2327-2334
    • (2005) Philos Trans R Soc Lond, B, Biol Sci , vol.360 , pp. 2327-2334
    • Cave, A.1    Grieve, D.2    Johar, S.3    Zhang, M.4    Shah, A.M.5
  • 10
    • 44049105970 scopus 로고    scopus 로고
    • Mechanisms of vitexin preconditioning effects on cultured neonatal rat cardiomyocytes with anoxia and reoxygenation
    • 18457368 10.1142/S0192415X08005849 1:CAS:528:DC%2BD1cXltl2hsLY%3D
    • Dong LY, Chen ZW, Guo Y, Cheng XP, Shao X (2008) Mechanisms of vitexin preconditioning effects on cultured neonatal rat cardiomyocytes with anoxia and reoxygenation. Am J Chin Med 36:385-397
    • (2008) Am J Chin Med , vol.36 , pp. 385-397
    • Dong, L.Y.1    Chen, Z.W.2    Guo, Y.3    Cheng, X.P.4    Shao, X.5
  • 11
    • 80054857698 scopus 로고    scopus 로고
    • Vitexin protects against myocardial ischemia/reperfusion injury in Langendorff-perfused rat hearts by attenuating inflammatory response and apoptosis
    • 22001368 10.1016/j.fct.2011.09.040 1:CAS:528:DC%2BC3MXhsFSjt7nP
    • Dong L, Fan Y, Shao X, Chen Z (2011) Vitexin protects against myocardial ischemia/reperfusion injury in Langendorff-perfused rat hearts by attenuating inflammatory response and apoptosis. Food Chem Toxicol 49:3211-3216
    • (2011) Food Chem Toxicol , vol.49 , pp. 3211-3216
    • Dong, L.1    Fan, Y.2    Shao, X.3    Chen, Z.4
  • 12
    • 79958168664 scopus 로고    scopus 로고
    • Casein kinase-2alpha1 induces hypertrophic response by phosphorylation of histone deacetylase 2 S394 and its activation in the heart
    • 21576649 10.1161/CIRCULATIONAHA.110.003665 1:CAS:528:DC%2BC3MXntVersbs%3D
    • Eom GH, Cho YK, Ko JH, Shin S, Choe N, Kim Y, Joung H, Kim HS, Nam KI, Kee HJ, Kook H (2011) Casein kinase-2alpha1 induces hypertrophic response by phosphorylation of histone deacetylase 2 S394 and its activation in the heart. Circulation 123:2392-2403
    • (2011) Circulation , vol.123 , pp. 2392-2403
    • Eom, G.H.1    Cho, Y.K.2    Ko, J.H.3    Shin, S.4    Choe, N.5    Kim, Y.6    Joung, H.7    Kim, H.S.8    Nam, K.I.9    Kee, H.J.10    Kook, H.11
  • 13
    • 0029941259 scopus 로고    scopus 로고
    • Action of the calcium channel blocker lacidipine on cardiac hypertrophy and endothelin-1 gene expression in stroke-prone hypertensive rats
    • 8762091 10.1111/j.1476-5381.1996.tb15451.x 1:CAS:528:DyaK28Xjs1Gitro%3D
    • Feron O, Salomone S, Godfraind T (1996) Action of the calcium channel blocker lacidipine on cardiac hypertrophy and endothelin-1 gene expression in stroke-prone hypertensive rats. Br J Pharmacol 118:659-664
    • (1996) Br J Pharmacol , vol.118 , pp. 659-664
    • Feron, O.1    Salomone, S.2    Godfraind, T.3
  • 15
    • 34249035782 scopus 로고    scopus 로고
    • Cardiac hypertrophy: Mechanisms and therapeutic opportunities
    • 17511580 10.1089/ars.2007.1474 1:CAS:528:DC%2BD2sXlsVOqs7c%3D
    • Gupta S, Das B, Sen S (2007) Cardiac hypertrophy: mechanisms and therapeutic opportunities. Antioxid Redox Signal 9:623-652
    • (2007) Antioxid Redox Signal , vol.9 , pp. 623-652
    • Gupta, S.1    Das, B.2    Sen, S.3
  • 16
    • 68849091992 scopus 로고    scopus 로고
    • Quercetin prevents cardiac hypertrophy induced by pressure overload in rats
    • 19578281 10.1292/jvms.71.737 1:CAS:528:DC%2BD1MXovFOgsrk%3D
    • Han JJ, Hao J, Kim CH, Hong JS, Ahn HY, Lee YS (2009) Quercetin prevents cardiac hypertrophy induced by pressure overload in rats. J Vet Med Sci 71:737-743
    • (2009) J Vet Med Sci , vol.71 , pp. 737-743
    • Han, J.J.1    Hao, J.2    Kim, C.H.3    Hong, J.S.4    Ahn, H.Y.5    Lee, Y.S.6
  • 18
    • 33748323383 scopus 로고    scopus 로고
    • Regulation of cardiac hypertrophy by intracellular signalling pathways
    • 16936699 10.1038/nrm1983 1:CAS:528:DC%2BD28Xot1Cqu78%3D
    • Heineke J, Molkentin JD (2006) Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol 7:589-600
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 589-600
    • Heineke, J.1    Molkentin, J.D.2
  • 19
    • 1542317022 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein phosphatase calcineurin mediates the expression of iNOS through IKK and NF-kappaB activity in LPS-stimulated mouse peritoneal macrophages and RAW 264.7 cells
    • 14741691 10.1016/j.bbrc.2003.12.153 1:CAS:528:DC%2BD2cXltF2jsg%3D%3D
    • 2+/calmodulin-dependent protein phosphatase calcineurin mediates the expression of iNOS through IKK and NF-kappaB activity in LPS-stimulated mouse peritoneal macrophages and RAW 264.7 cells. Biochem Biophys Res Commun 314:695-703
    • (2004) Biochem Biophys Res Commun , vol.314 , pp. 695-703
    • Kim, Y.1    Moon, J.S.2    Lee, K.S.3    Park, S.Y.4    Cheong, J.5    Kang, H.S.6    Lee, H.Y.7    Kim, H.D.8
  • 20
    • 21844478316 scopus 로고    scopus 로고
    • The isolation and antioxidative effects of vitexin from Acer palmatum
    • 15789751 10.1007/BF02977715 1:CAS:528:DC%2BD2MXisFGgs7s%3D
    • Kim JH, Lee BC, Kim JH, Sim GS, Lee DH, Lee KE, Yun YP, Pyo HB (2005) The isolation and antioxidative effects of vitexin from Acer palmatum. Arch Pharm Res 28(2):195-202
    • (2005) Arch Pharm Res. , vol.28 , Issue.2 , pp. 195-202
    • Kim, J.H.1    Lee, B.C.2    Kim, J.H.3    Sim, G.S.4    Lee, D.H.5    Lee, K.E.6    Yun, Y.P.7    Pyo, H.B.8
  • 22
    • 0034705070 scopus 로고    scopus 로고
    • Calcineurin expression, activation, and function in cardiac pressure-overload hypertrophy
    • 10821822 10.1161/01.CIR.101.20.2431 1:CAS:528:DC%2BD3cXktVGgtbw%3D
    • Lim HW, De Windt LJ, Steinberg L, Taigen T, Witt SA, Kimball TR, Molkentin JD (2000) Calcineurin expression, activation, and function in cardiac pressure-overload hypertrophy. Circulation 101:2431-2437
    • (2000) Circulation , vol.101 , pp. 2431-2437
    • Lim, H.W.1    De Windt, L.J.2    Steinberg, L.3    Taigen, T.4    Witt, S.A.5    Kimball, T.R.6    Molkentin, J.D.7
  • 25
    • 57849118885 scopus 로고    scopus 로고
    • Influence of the extraction mode on the yield of hyperoside, vitexin and vitexin-2″-O-rhamnoside from Crataegus monogyna Jacq. (hawthorn)
    • 18618435 10.1002/pca.1081 1:CAS:528:DC%2BD1cXhsVaitb7F
    • Martino E, Collina S, Rossi D, Bazzoni D, Gaggeri R, Bracco F, Azzolina O (2008) Influence of the extraction mode on the yield of hyperoside, vitexin and vitexin-2″-O-rhamnoside from Crataegus monogyna Jacq. (hawthorn). Phytochem Anal 19:534-540
    • (2008) Phytochem Anal , vol.19 , pp. 534-540
    • Martino, E.1    Collina, S.2    Rossi, D.3    Bazzoni, D.4    Gaggeri, R.5    Bracco, F.6    Azzolina, O.7
  • 29
    • 52949108394 scopus 로고    scopus 로고
    • Molecular mechanisms underlying the transition of cardiac hypertrophy to heart failure
    • 18772527 10.1253/circj.CJ-08-0481
    • Oka T, Komuro I (2008) Molecular mechanisms underlying the transition of cardiac hypertrophy to heart failure. Circ J 72(A):A13-16
    • (2008) Circ J , vol.72 , pp. 13-16
    • Oka, T.1    Komuro, I.2
  • 31
    • 77649342305 scopus 로고    scopus 로고
    • Molecular targets and regulators of cardiac hypertrophy
    • 19969085 10.1016/j.phrs.2009.11.012 1:CAS:528:DC%2BC3cXjt1Wjt7k%3D
    • Rohini A, Agrawal N, Koyani CN, Singh R (2010) Molecular targets and regulators of cardiac hypertrophy. Pharmacol Res 61:269-280
    • (2010) Pharmacol Res , vol.61 , pp. 269-280
    • Rohini, A.1    Agrawal, N.2    Koyani, C.N.3    Singh, R.4
  • 33
    • 0345258510 scopus 로고    scopus 로고
    • Regulation of hypertrophic and apoptotic signaling pathways by reactive oxygen species in cardiac myocytes. Antioxid
    • 10.1089/152308603770380034 1:CAS:528:DC%2BD3sXosFWqsL8%3D
    • Sabri A, Hughie HH, Lucchesi PA (2003) Regulation of hypertrophic and apoptotic signaling pathways by reactive oxygen species in cardiac myocytes. Antioxid. Redox Signal 5:731-740
    • (2003) Redox Signal , vol.5 , pp. 731-740
    • Sabri, A.1    Hughie, H.H.2    Lucchesi, P.A.3
  • 34
    • 10744223962 scopus 로고    scopus 로고
    • Roles of calcineurin and calcium/calmodulin-dependent protein kinase II in pressure overload-induced cardiac hypertrophy
    • 12967638 10.1016/S0022-2828(03)00234-7 1:CAS:528:DC%2BD3sXmvVOrsbY%3D
    • Saito T, Fukuzawa J, Osaki J, Sakuragi H, Yao N, Haneda T, Fujino T, Wakamiya N, Kikuchi K, Hasebe N (2003) Roles of calcineurin and calcium/calmodulin-dependent protein kinase II in pressure overload-induced cardiac hypertrophy. J Mol Cell Cardiol 35:1153-1160
    • (2003) J Mol Cell Cardiol , vol.35 , pp. 1153-1160
    • Saito, T.1    Fukuzawa, J.2    Osaki, J.3    Sakuragi, H.4    Yao, N.5    Haneda, T.6    Fujino, T.7    Wakamiya, N.8    Kikuchi, K.9    Hasebe, N.10
  • 35
    • 33751184396 scopus 로고    scopus 로고
    • Mechanisms of cardiac hypertrophy
    • 17386851 10.1016/j.hfc.2005.03.006
    • Selvetella G, Lembo G (2005) Mechanisms of cardiac hypertrophy. Heart Fail Clin 1:263-273
    • (2005) Heart Fail Clin , vol.1 , pp. 263-273
    • Selvetella, G.1    Lembo, G.2
  • 36
    • 84873056069 scopus 로고    scopus 로고
    • Bone morphogenetic protein-4 mediates cardiac hypertrophy, apoptosis, and fibrosis in experimentally pathological cardiac hypertrophy
    • 23248151 10.1161/HYPERTENSIONAHA.111.00562
    • Sun B, Huo R, Sheng Y, Li Y, Xie X, Chen C, Liu H-B, Li N, Li C-B, Guo W-T, Zhu J-X, Yang B-F, Dong D-L (2012) Bone morphogenetic protein-4 mediates cardiac hypertrophy, apoptosis, and fibrosis in experimentally pathological cardiac hypertrophy. Hypertension 61(2):352-60
    • (2012) Hypertension , vol.61 , Issue.2 , pp. 352-360
    • Sun, B.1    Huo, R.2    Sheng, Y.3    Li, Y.4    Xie, X.5    Chen, C.6    Liu, H.-B.7    Li, N.8    Li, C.-B.9    Guo, W.-T.10    Zhu, J.-X.11    Yang, B.-F.12    Dong, D.-L.13
  • 38
    • 84864448450 scopus 로고    scopus 로고
    • Choline inhibits angiotensin II-induced cardiac hypertrophy by intracellular calcium signal and p38 MAPK pathway
    • 22569796 10.1007/s00210-012-0740-4 1:CAS:528:DC%2BC38XhtVemu73P
    • Wang S, Han HM, Pan ZW, Hang PZ, Sun LH, Jiang YN, Song HX, Du ZM, Liu Y (2012) Choline inhibits angiotensin II-induced cardiac hypertrophy by intracellular calcium signal and p38 MAPK pathway. Naunyn Schmiedebergs Arch Pharmacol 385:823-831
    • (2012) Naunyn Schmiedebergs Arch Pharmacol , vol.385 , pp. 823-831
    • Wang, S.1    Han, H.M.2    Pan, Z.W.3    Hang, P.Z.4    Sun, L.H.5    Jiang, Y.N.6    Song, H.X.7    Du, Z.M.8    Liu, Y.9
  • 40
    • 4444382387 scopus 로고    scopus 로고
    • Calcium-calcineurin signaling in the regulation of cardiac hypertrophy
    • 15336966 10.1016/j.bbrc.2004.07.121 1:CAS:528:DC%2BD2cXntFequrw%3D
    • Wilkins BJ, Molkentin JD (2004) Calcium-calcineurin signaling in the regulation of cardiac hypertrophy. Biochem Biophys Res Commun 322:1178-1191
    • (2004) Biochem Biophys Res Commun , vol.322 , pp. 1178-1191
    • Wilkins, B.J.1    Molkentin, J.D.2
  • 41
    • 0036837672 scopus 로고    scopus 로고
    • Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth
    • 12370307 10.1128/MCB.22.21.7603-7613.2002 1:CAS:528:DC%2BD38XotVKhsbg%3D
    • Wilkins BJ, De Windt LJ, Bueno OF, Braz JC, Glascock BJ, Kimball TF, Molkentin JD (2002) Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth. Mol Cell Biol 22(21):7603-7613
    • (2002) Mol Cell Biol , vol.22 , Issue.21 , pp. 7603-7613
    • Wilkins, B.J.1    De Windt, L.J.2    Bueno, O.F.3    Braz, J.C.4    Glascock, B.J.5    Kimball, T.F.6    Molkentin, J.D.7
  • 42
    • 0347320747 scopus 로고    scopus 로고
    • Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy
    • 14656927 10.1161/01.RES.0000109415.17511.18 1:CAS:528:DC%2BD2cXhtFSr
    • Wilkins BJ, Dai YS, Bueno OF, Parsons SA, Xu J, Plank DM, Jones F, Kimball TR, Molkentin JD (2004) Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy. Circ Res 94:110-118
    • (2004) Circ Res , vol.94 , pp. 110-118
    • Wilkins, B.J.1    Dai, Y.S.2    Bueno, O.F.3    Parsons, S.A.4    Xu, J.5    Plank, D.M.6    Jones, F.7    Kimball, T.R.8    Molkentin, J.D.9
  • 43
    • 84860309531 scopus 로고    scopus 로고
    • Effect of EGb and quercetin on culture neonatal rat cardiomyocytes hypertrophy and mechanism
    • 21179752 1:CAS:528:DC%2BD1cXivFensL8%3D
    • Wu Y, Gu YM (2007) Effect of EGb and quercetin on culture neonatal rat cardiomyocytes hypertrophy and mechanism. Zhongguo Ying Yong Sheng Li Xue Za Zhi 23:138-142
    • (2007) Zhongguo Ying Yong Sheng Li Xue Za Zhi , vol.23 , pp. 138-142
    • Wu, Y.1    Gu, Y.M.2
  • 44
    • 84880721583 scopus 로고    scopus 로고
    • The novel p53-dependent metastatic and apoptotic pathway induced by vitexin in human oral cancer OC2 cells
    • 10.1002/ptr.4841
    • Yang SH, Liao PH, Pan YF, Chen SL, Chou SS, Chou MY (2012) The novel p53-dependent metastatic and apoptotic pathway induced by vitexin in human oral cancer OC2 cells. Phytother Res doi: 10.1002/ptr.4841
    • (2012) Phytother Res
    • Yang, S.H.1    Liao, P.H.2    Pan, Y.F.3    Chen, S.L.4    Chou, S.S.5    Chou, M.Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.