Overexpression of calmodulin induces cardiac hypertrophy by a calcineurin-dependent pathway

Biochemical and Biophysical Research Communications

Volumn 338, Issue 2, 2005, Pages 1299-1305

  Obata, Koji ^a   Nagata, Kohzo ^b   Iwase, Mitsunori ^b   Odashima, Mari ^a   Nagasaka, Tetsuro ^c   Izawa, Hideo ^c   Murohara, Toyoaki ^c   Yamada, Yoshiji ^d   Yokota, Mitsuhiro ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d MIE UNIVERSITY   (Japan)

Author keywords

Calcineurin; Calmodulin; Cardiac hypertrophy; FK506; Transgenic mouse

Indexed keywords

ATRIAL NATRIURETIC FACTOR; CALCINEURIN; CALCINEURIN INHIBITOR; CALMODULIN; MYOSIN HEAVY CHAIN; MYOSIN HEAVY CHAIN BETA; TACROLIMUS; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CELL SIZE; CONTROLLED STUDY; GENE EXPRESSION; HEART; HEART CELL CULTURE; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HEART WEIGHT; INHIBITION KINETICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PERINATAL PERIOD; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TRANSGENIC MOUSE; UPREGULATION; WILD TYPE;

ANIMALS; CALCINEURIN; CALMODULIN; CARDIOMEGALY; CELLS, CULTURED; MICE; MICE, TRANSGENIC; MYOCYTES, CARDIAC; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; UP-REGULATION;

ANIMALIA; MUS MUSCULUS;

EID: 27744588009     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.10.083     Document Type: Article

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