-
1
-
-
0001555950
-
Complex pyridine nucleotide-dependent transformations
-
In; Dolphin, D. Poulson, R. Avramovic, O. John Wiley & Sons: New York, Vol, pp and references therein.
-
Frey, P. A. Complex pyridine nucleotide-dependent transformations. In Pyridine Nucleotide Coenzymes: Chemical, Biochemical, and Medical Aspects; Dolphin, D., Poulson, R., Avramovic, O., Eds.; John Wiley & Sons: New York, 1987; Vol 2B, pp 461-511 and references therein.
-
(1987)
Pyridine Nucleotide Coenzymes: Chemical, Biochemical, and Medical Aspects
, vol.2
, pp. 461-511
-
-
Frey, P.A.1
-
2
-
-
0242498430
-
Structure and function of enzymes of the Leloir pathway for galactose metabolism
-
Holden, H. M.; Rayment, I.; Thoden, J. B. Structure and function of enzymes of the Leloir pathway for galactose metabolism J. Biol. Chem. 2003, 278, 43885-43888
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 43885-43888
-
-
Holden, H.M.1
Rayment, I.2
Thoden, J.B.3
-
3
-
-
0026736606
-
The molecular structure of UDP-galactose 4-epimerase from Escherichia coli determined at 2.5 Å resolution
-
Bauer, A. J.; Rayment, I.; Frey, P. A.; Holden, H. M. The molecular structure of UDP-galactose 4-epimerase from Escherichia coli determined at 2.5 Å resolution Proteins 1992, 12, 372-381
-
(1992)
Proteins
, vol.12
, pp. 372-381
-
-
Bauer, A.J.1
Rayment, I.2
Frey, P.A.3
Holden, H.M.4
-
4
-
-
0029849211
-
X-ray structure of UDP-galactose 4-epimerase complexed with UDP-phenol
-
Thoden, J. B.; Frey, P. A.; Holden High-resolution, H. M. X-ray structure of UDP-galactose 4-epimerase complexed with UDP-phenol Protein Sci. 1996, 5, 2149-2161
-
(1996)
Protein Sci.
, vol.5
, pp. 2149-2161
-
-
Thoden, J.B.1
Frey, P.A.2
Holden High-Resolution, H.M.3
-
5
-
-
0029921058
-
Molecular structure of he NADH/UDP-glucose abortive complex of UDP-galactose 4-epimerase from Escherichia coli: Implications for the catalytic mechanism
-
Thoden, J. B.; Frey, P. A.; Holden, H. M. Molecular structure of he NADH/UDP-glucose abortive complex of UDP-galactose 4-epimerase from Escherichia coli: Implications for the catalytic mechanism Biochemistry 1996, 35, 5137-5144
-
(1996)
Biochemistry
, vol.35
, pp. 5137-5144
-
-
Thoden, J.B.1
Frey, P.A.2
Holden, H.M.3
-
6
-
-
0029877040
-
Crystal structures of the oxidized and reduced forms of UDP-galactose 4-epimerase isolated from Escherichia coli
-
Thoden, J. B.; Frey, P. A.; Holden, H. M. Crystal structures of the oxidized and reduced forms of UDP-galactose 4-epimerase isolated from Escherichia coli Biochemistry 1996, 35, 2557-2566
-
(1996)
Biochemistry
, vol.35
, pp. 2557-2566
-
-
Thoden, J.B.1
Frey, P.A.2
Holden, H.M.3
-
7
-
-
0029032964
-
MolView: A program for analyzing and displaying atomic structures on the Macintosh personal computer
-
Smith, T. J. MolView: A program for analyzing and displaying atomic structures on the Macintosh personal computer J. Mol. Graphics 1995, 13, 122-125
-
(1995)
J. Mol. Graphics
, vol.13
, pp. 122-125
-
-
Smith, T.J.1
-
8
-
-
0034673977
-
Crystallographic evidence for Tyr157 functioning as the active site base in human UDP-galactose 4-epimerase
-
Thoden, J. B.; Wohlers, T. M.; Fridovich-Keil, J. L.; Holden, H. M. Crystallographic evidence for Tyr157 functioning as the active site base in human UDP-galactose 4-epimerase Biochemistry 2000, 39, 5691-5701
-
(2000)
Biochemistry
, vol.39
, pp. 5691-5701
-
-
Thoden, J.B.1
Wohlers, T.M.2
Fridovich-Keil, J.L.3
Holden, H.M.4
-
9
-
-
0029904287
-
+ content and a charge-transfer band associated with the substrate-induced conformational transition
-
+ content and a charge-transfer band associated with the substrate-induced conformational transition Biochemistry 1996, 35, 7615-7620
-
(1996)
Biochemistry
, vol.35
, pp. 7615-7620
-
-
Liu, Y.1
Vanhooke, J.L.2
Frey, P.A.3
-
10
-
-
7144221518
-
Dehydration in nucleotide-linked deoxysugar synthesis
-
In, 3rd ed. Boyer, P. D. Academic Press: New York, Vol.
-
Glaser, L.; Zarkowsky, H. Dehydration in nucleotide-linked deoxysugar synthesis. In The Enzymes, 3rd ed.; Boyer, P. D., Ed.; Academic Press: New York, 1971; Vol. 5, pp 465-479.
-
(1971)
The Enzymes
, vol.5
, pp. 465-479
-
-
Glaser, L.1
Zarkowsky, H.2
-
11
-
-
0033539608
-
Crystal structure of SQD1, an enzyme involved in the biosynthesis of the plant sulfolipid headgroup donor UDP-sulfoquinovose
-
Mulichack, A. M.; Theisen, M. J.; Essigman, B.; Benning, C.; Garavito, R. M. Crystal structure of SQD1, an enzyme involved in the biosynthesis of the plant sulfolipid headgroup donor UDP-sulfoquinovose Proc. Natl. Acad. Sci. U.S.A. 1999, 96, 13097-13102
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 13097-13102
-
-
Mulichack, A.M.1
Theisen, M.J.2
Essigman, B.3
Benning, C.4
Garavito, R.M.5
-
12
-
-
0034658405
-
The crystal structure of ADP-L-glycero-D-mannoheptose 6-epimerase: Catalysis with a twist
-
Deacon, A. M.; Ni, Y. S.; Coleman, W. G., Jr.; Ealick, S. E. The crystal structure of ADP-L-glycero-D-mannoheptose 6-epimerase: Catalysis with a twist Structure 2000, 8, 453-462
-
(2000)
Structure
, vol.8
, pp. 453-462
-
-
Deacon, A.M.1
Ni, Y.S.2
Coleman Jr., W.G.3
Ealick, S.E.4
-
13
-
-
0039333155
-
New insights into the mechanism of CDP- d -tyvelose 2-epimerase: An enzyme catalyzing epimerization at an unactivated stereocenter
-
Hallis, T. M.; Zhao, Z.; Liu, H.-w. New insights into the mechanism of CDP- d -tyvelose 2-epimerase: An enzyme catalyzing epimerization at an unactivated stereocenter J. Am. Chem. Soc. 2000, 122, 10493-10503
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 10493-10503
-
-
Hallis, T.M.1
Zhao, Z.2
Liu, H.-W.3
-
14
-
-
0034737458
-
Deoxyhypusine synthase generates and uses bound NADH in a transient hydride transfer mechanism
-
Wolff, E. C.; Wolff, J.; Park, M. H. Deoxyhypusine synthase generates and uses bound NADH in a transient hydride transfer mechanism J. Biol. Chem. 2000, 275, 9170-9177
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 9170-9177
-
-
Wolff, E.C.1
Wolff, J.2
Park, M.H.3
-
15
-
-
0032518247
-
Crystal structure of the NAD complex of human deoxyhypusine synthase: An enzyme with a ball-and-chain mechanism for blocking the active site
-
Liao, D.-I.; Wolff, E. C.; Park, M. H.; Davies, D. R. Crystal structure of the NAD complex of human deoxyhypusine synthase: An enzyme with a ball-and-chain mechanism for blocking the active site Structure 1998, 6, 23-32
-
(1998)
Structure
, vol.6
, pp. 23-32
-
-
Liao, D.-I.1
Wolff, E.C.2
Park, M.H.3
Davies, D.R.4
-
16
-
-
0030969906
-
Structural analysis of UDP-sugar binding to UDP-galactose 4-epimerase from Escherichia coli
-
Thoden, J. B.; Hegeman, A. D.; Wesenberg, G.; Chapeau, M. C.; Frey, P. A.; Holden, H. M. Structural analysis of UDP-sugar binding to UDP-galactose 4-epimerase from Escherichia coli Biochemistry 1997, 36, 6294-6304
-
(1997)
Biochemistry
, vol.36
, pp. 6294-6304
-
-
Thoden, J.B.1
Hegeman, A.D.2
Wesenberg, G.3
Chapeau, M.C.4
Frey, P.A.5
Holden, H.M.6
-
17
-
-
0032544212
-
Dramatic differences in binding of UDP-galactose and UDP-glucose to UDP-galactose 4-epimerase from Escherichia coli
-
Thoden, J. B.; Holden, H. M. Dramatic differences in binding of UDP-galactose and UDP-glucose to UDP-galactose 4-epimerase from Escherichia coli Biochemistry 1998, 37, 11469-11477
-
(1998)
Biochemistry
, vol.37
, pp. 11469-11477
-
-
Thoden, J.B.1
Holden, H.M.2
-
18
-
-
0029065611
-
Short-chain dehydrogenases/reductases
-
In; Weiner, H. Holmes, R. S. Wermuth, B. Plenum Press: New York
-
Persson, B.; Krook, M.; Jörnvall, H. Short-chain dehydrogenases/reductases. In Enzymology and Molecular Biology of Carbonyl Metabolism 5; Weiner, H.; Holmes, R. S.; Wermuth, B., Eds.; Plenum Press: New York, 1995; pp 383-395.
-
(1995)
Enzymology and Molecular Biology of Carbonyl Metabolism 5
, pp. 383-395
-
-
Persson, B.1
Krook, M.2
Jörnvall, H.3
-
19
-
-
0026521505
-
Expansion of the mammalian 3-beta-hydroxysteroid dehydrogenase/plannd dihydroflavonol reductase superfamily to include a bacterial cholesterol dehydrognease, a bacterial UDP-galactose-4-epimerase, and open reading frames in vaccinia virus and fish lymphocystis disease virus
-
Baker, M. E.; Blasco, R. Expansion of the mammalian 3-beta-hydroxysteroid dehydrogenase/plannd dihydroflavonol reductase superfamily to include a bacterial cholesterol dehydrognease, a bacterial UDP-galactose-4-epimerase, and open reading frames in vaccinia virus and fish lymphocystis disease virus FEBS Lett. 1992, 301, 89-93
-
(1992)
FEBS Lett.
, vol.301
, pp. 89-93
-
-
Baker, M.E.1
Blasco, R.2
-
20
-
-
0028402721
-
Three sisters, different names
-
Holm, L.; Sander, C.; Murzin, A. Three sisters, different names Nat. Struct. Biol. 1994, 1, 146-147
-
(1994)
Nat. Struct. Biol.
, vol.1
, pp. 146-147
-
-
Holm, L.1
Sander, C.2
Murzin, A.3
-
21
-
-
0030832007
-
Mechanistic roles of tyrosine 149 and serine 124 in UDP-galactose 4-epimerase from Escherichia coli
-
Liu, Y.; Thoden, J. B.; Kim, J.; Berger, E.; Gulick, A. M.; Ruzicka, F. J.; Holden, H. M.; Frey, P. A. Mechanistic roles of tyrosine 149 and serine 124 in UDP-galactose 4-epimerase from Escherichia coli Biochemistry 1997, 36, 10675-10684
-
(1997)
Biochemistry
, vol.36
, pp. 10675-10684
-
-
Liu, Y.1
Thoden, J.B.2
Kim, J.3
Berger, E.4
Gulick, A.M.5
Ruzicka, F.J.6
Holden, H.M.7
Frey, P.A.8
-
22
-
-
0030803238
-
Molecular structures of the S124A, S124T, and S124V site-directed mutants of UDP-galactose 4-epimerase from Escherichia coli
-
Thoden, J. B.; Gulick, A. M.; Holden, H. M. Molecular structures of the S124A, S124T, and S124V site-directed mutants of UDP-galactose 4-epimerase from Escherichia coli Biochemistry 1997, 36, 10685-10695
-
(1997)
Biochemistry
, vol.36
, pp. 10685-10695
-
-
Thoden, J.B.1
Gulick, A.M.2
Holden, H.M.3
-
24
-
-
0018595736
-
Uridine diphosphate galactose 4-epimerase. Alkylation of enzyme-bound diphosphopyridine nucleotide by p -(bromoacetamido) phenyl uridyl pyrophosphate, an active-site-directed irreversible inhibitor
-
Wong, Y.-H.; Frey, P. A. Uridine diphosphate galactose 4-epimerase. Alkylation of enzyme-bound diphosphopyridine nucleotide by p -(bromoacetamido) phenyl uridyl pyrophosphate, an active-site-directed irreversible inhibitor Biochemistry 1979, 18, 5337-5341
-
(1979)
Biochemistry
, vol.18
, pp. 5337-5341
-
-
Wong, Y.-H.1
Frey, P.A.2
-
25
-
-
0025219507
-
The reaction of uridine diphosphate galactose 4-epimerase with a suicide inactivator
-
Flentke, G. R.; Frey, P. A. The reaction of uridine diphosphate galactose 4-epimerase with a suicide inactivator Biochemistry 1990, 29, 2430-2436
-
(1990)
Biochemistry
, vol.29
, pp. 2430-2436
-
-
Flentke, G.R.1
Frey, P.A.2
-
26
-
-
0035811065
-
Acid-base catalysis by UDP-galactose 4-epimerase: Correlations of kinetically measured acid dissociation constants with thermodynamic values for tyrosine 149
-
Berger, E.; Arabshahi, A.; Wei, Y.; Schilling, J. F.; Frey, P. A. Acid-base catalysis by UDP-galactose 4-epimerase: Correlations of kinetically measured acid dissociation constants with thermodynamic values for tyrosine 149 Biochemistry 2001, 40, 6699-6705
-
(2001)
Biochemistry
, vol.40
, pp. 6699-6705
-
-
Berger, E.1
Arabshahi, A.2
Wei, Y.3
Schilling, J.F.4
Frey, P.A.5
-
27
-
-
0019524346
-
PH variation of isotope effects in enzyme-catalyzed reactions. 1. Isotope- and pH-dependent steps the same
-
Cook, P.; Cleland, W. W. pH variation of isotope effects in enzyme-catalyzed reactions. 1. Isotope- and pH-dependent steps the same Biochemistry 1981, 20, 1797-1805
-
(1981)
Biochemistry
, vol.20
, pp. 1797-1805
-
-
Cook, P.1
Cleland, W.W.2
-
28
-
-
0019472074
-
PH variation of isotope effects in enzyme catalyzed reactions. 2. Isotope-dependent step not pH-dependent. Kinetic mechanism of alcohol dehydrogenase
-
Cook, P.; Cleland, W. W. pH variation of isotope effects in enzyme catalyzed reactions. 2. Isotope-dependent step not pH-dependent. Kinetic mechanism of alcohol dehydrogenase Biochemistry 1981, 20, 1806-1816
-
(1981)
Biochemistry
, vol.20
, pp. 1806-1816
-
-
Cook, P.1
Cleland, W.W.2
-
29
-
-
0023864607
-
Uridine diphosphate galactose 4-epimerase. pH-dependence of the reduction of NAD+ by a substrate analog
-
Arabshahi, A.; Flentke, G. R.; Frey, P. A. Uridine diphosphate galactose 4-epimerase. pH-dependence of the reduction of NAD+ by a substrate analog J. Biol. Chem. 1988, 263, 2638-2643
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 2638-2643
-
-
Arabshahi, A.1
Flentke, G.R.2
Frey, P.A.3
-
30
-
-
0027740162
-
Identification of lysine 153 as a functionally important residue in UDP-galactose 4-epimerase from Escherichia coli
-
Swanson, B. A.; Frey, P. A. Identification of lysine 153 as a functionally important residue in UDP-galactose 4-epimerase from Escherichia coli Biochemistry 1993, 32, 13231-13236
-
(1993)
Biochemistry
, vol.32
, pp. 13231-13236
-
-
Swanson, B.A.1
Frey, P.A.2
-
34
-
-
0035908888
-
+ and active site residues of UDP-galactose 4-epimerase: Implications for the activation induced by uridine nucleotides
-
+ and active site residues of UDP-galactose 4-epimerase: Implications for the activation induced by uridine nucleotides Biochemistry 2001, 40, 11279-11287
-
(2001)
Biochemistry
, vol.40
, pp. 11279-11287
-
-
Wei, Y.1
Lin, J.2
Frey, P.A.3
-
35
-
-
0000607555
-
Correlation of electronic effects in N -alkylnicotinamides with NMR chemical shifts and hydride transfer reactivity
-
Burke, J. R.; Frey, P. A. Correlation of electronic effects in N -alkylnicotinamides with NMR chemical shifts and hydride transfer reactivity J. Org. Chem. 1996, 61, 530-533
-
(1996)
J. Org. Chem.
, vol.61
, pp. 530-533
-
-
Burke, J.R.1
Frey, P.A.2
-
37
-
-
0021035009
-
Co-purification and characterization of UDP-glucose 4-epimerase and UDP-N-acetylglucosamine 4-epimerase from porcine submaxillary glands
-
Piller, F.; Hanlon, M. H.; Hill, R. L. Co-purification and characterization of UDP-glucose 4-epimerase and UDP-N-acetylglucosamine 4-epimerase from porcine submaxillary glands J. Biol. Chem. 1983, 258, 10774-10778
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 10774-10778
-
-
Piller, F.1
Hanlon, M.H.2
Hill, R.L.3
-
38
-
-
0035805630
-
Human UDP-galactose 4-epimerase. Accommodation of UDP-N- acetylgalactosamine within the active site
-
Thoden, J. B.; Wohlers, T. M.; Fridovich-Keil, J. L.; Holden, H. M. Human UDP-galactose 4-epimerase. Accommodation of UDP-N-acetylgalactosamine within the active site J. Biol. Chem. 2001, 276, 15131-15136
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 15131-15136
-
-
Thoden, J.B.1
Wohlers, T.M.2
Fridovich-Keil, J.L.3
Holden, H.M.4
-
39
-
-
0037178867
-
Structural analysis of the Y229C mutant of Escherichia coli UDP-galactose 4-epimerase. Teaching an old dog new tricks
-
Thoden, J. B.; Henderson, J. M.; Fridovich-Keil, J. L.; Holden, H. M. Structural analysis of the Y229C mutant of Escherichia coli UDP-galactose 4-epimerase. Teaching an old dog new tricks J. Biol. Chem. 2002, 277, 27528-27534
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 27528-27534
-
-
Thoden, J.B.1
Henderson, J.M.2
Fridovich-Keil, J.L.3
Holden, H.M.4
-
40
-
-
2542500431
-
Crystal structure of WbpP, a genuine UDP-N-acetylglucosamine 4-epimerase from Pseudomonas aerugnosa: Substrate specificity in UDP-hexose 4-epimerases
-
Ishiyama, N.; Creuzenet, C.; Lam, J. S.; Berghuis, A. M. Crystal structure of WbpP, a genuine UDP-N-acetylglucosamine 4-epimerase from Pseudomonas aerugnosa: Substrate specificity in UDP-hexose 4-epimerases J. Biol. Chem. 2004, 279, 22635-22642
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 22635-22642
-
-
Ishiyama, N.1
Creuzenet, C.2
Lam, J.S.3
Berghuis, A.M.4
-
41
-
-
3543045527
-
Determinants of function and substrate specificity in human UDP-galactose 4-epimerase
-
Schulz, J. M.; Watson, A. L.; Sanders, R.; Ross, K. L.; Thoden, J. B.; Holden, H. M.; Fridovich-Keil, J. L. Determinants of function and substrate specificity in human UDP-galactose 4-epimerase J. Biol. Chem. 2004, 279, 32796-32803
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 32796-32803
-
-
Schulz, J.M.1
Watson, A.L.2
Sanders, R.3
Ross, K.L.4
Thoden, J.B.5
Holden, H.M.6
Fridovich-Keil, J.L.7
-
42
-
-
33751250543
-
Biochemical characterization of UDP-GlcNAc/Glc 4-epimerase from Escherichia coli 086:B7
-
Guo, H.; Li, L.; Wang, P. G. Biochemical characterization of UDP-GlcNAc/Glc 4-epimerase from Escherichia coli 086:B7 Biochemistry 2006, 45, 13760-13768
-
(2006)
Biochemistry
, vol.45
, pp. 13760-13768
-
-
Guo, H.1
Li, L.2
Wang, P.G.3
-
43
-
-
0017314896
-
UDP galactose 4-epimerase catalyzed oxygen dependent reduction of a free radical substrate analogue by two electron reducing agents
-
Wong, S. S.; Frey, P. A. UDP galactose 4-epimerase catalyzed oxygen dependent reduction of a free radical substrate analogue by two electron reducing agents J. Am. Chem. Soc. 1976, 98, 7886-7887
-
(1976)
J. Am. Chem. Soc.
, vol.98
, pp. 7886-7887
-
-
Wong, S.S.1
Frey, P.A.2
-
44
-
-
0001188544
-
Stable free radicals. I. Isolation and distillation of 1-ethyl-4-carbomethoxypyridinyl
-
Kosower, E. M.; Poziomek, E. J. Stable free radicals. I. Isolation and distillation of 1-ethyl-4-carbomethoxypyridinyl J. Am. Chem. Soc. 1964, 86, 5515-5523
-
(1964)
J. Am. Chem. Soc.
, vol.86
, pp. 5515-5523
-
-
Kosower, E.M.1
Poziomek, E.J.2
-
46
-
-
0003708891
-
The pyridinium-dihydropyridine system. Part 2. Substituent effects on the oxidation of 1,4-dihydropyridines by flavins
-
Stewart, R.; Norria, S. J. The pyridinium-dihydropyridine system. Part 2. Substituent effects on the oxidation of 1,4-dihydropyridines by flavins J. Chem. Soc., Perkin Trans. 2 (1972-1999) 1978, 246-249
-
(1978)
J. Chem. Soc., Perkin Trans. 2 (1972-1999)
, pp. 246-249
-
-
Stewart, R.1
Norria, S.J.2
-
47
-
-
0020174052
-
- transfer in reduction by dihydronicotinamide reaction of oxidized flavin and flavin radical with N-benzyl-1,4- dihydronicotinamide
-
- transfer in reduction by dihydronicotinamide reaction of oxidized flavin and flavin radical with N-benzyl-1,4-dihydronicotinamide Proc. Natl. Acad. Sci. U.S.A. 1982, 79, 4604-4608
-
(1982)
Proc. Natl. Acad. Sci. U.S.A.
, vol.79
, pp. 4604
-
-
Powell, M.F.1
Wong, W.H.2
Bruice, T.C.3
|