Antimicrobial activity of nanoemulsion in combination with cetylpyridinium chloride in multidrug-resistant acinetobacter baumannii

Antimicrobial Agents and Chemotherapy

Volumn 57, Issue 8, 2013, Pages 3568-3575

  Hwang, Yoon Y ^a   Ramalingam, Karthikeyan ^b   Bienek, Diane R ^a   Lee, Valerie ^b   You, Tao ^c   Alvarez, Rene ^a  

^a Naval Medical Research Unit San Antonio   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c US ARMY INSTITUTE OF SURGICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; CETYLPYRIDINIUM SALT; DETERGENT; OIL; SODIUM CHLORIDE; SOYBEAN OIL; TRITON X 100;

ACINETOBACTER BAUMANNII; AFGHANISTAN; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIUM ISOLATION; BIOFILM; CELL PROLIFERATION; COLONY FORMING UNIT; IRAQ; MULTIDRUG RESISTANCE; NANOEMULSION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY;

ACINETOBACTER BAUMANNII; ANTI-BACTERIAL AGENTS; BACTERIAL LOAD; BIOFILMS; CETYLPYRIDINIUM; DRUG RESISTANCE, MULTIPLE, BACTERIAL; DRUG STABILITY; DRUG SYNERGISM; EMULSIONS; ETHANOL; MICROBIAL SENSITIVITY TESTS; MICROBIAL VIABILITY; NANOTECHNOLOGY; OCTOXYNOL; PARTICLE SIZE; SODIUM CHLORIDE; SOYBEAN OIL;

EID: 84880262179     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.02109-12     Document Type: Article

References (35)

1. Peleg AY, Seifert H, Paterson DL. 2008. Acinetobacter baumannii: emergence of a successful pathogen. Clin. Microbiol. Rev. 21:538-582.
2. Joly-Guillou ML. 2005. Clinical impact and pathogenicity of Acinetobacter. Clin. Microbiol. Infect. 11:868-873.
3. Sheppard FR, Keiser P, Craft DW, Gage F, Robson M, Brown TS, Petersen K, Sincock Kasper SM, Hawksworth J, Tadaki D, Davis TA, Stojadinovic A, Elster E. 2010. The majority of US combat casualty soft-tissue wounds are not infected or colonized upon arrival or during treatment at a continental US military medical facility. Am. J. Surg. 200: 489-495.
4. Neonakis IK, Spandidos DA, Petinaki E. 2011. Confronting multidrugresistant Acinetobacter baumannii: a review. Int. J. Antimicrob. Agents 37:102-109.
5. Navon-Venezia S, Ben-Ami R, Carmeli Y. 2005. Update on Pseudomonas aeruginosa and Acinetobacter baumannii infections in the healthcare setting. Curr. Opin. Infect. Dis. 18:306-313.
6. Fournier PE, Richet H. 2006. The epidemiology and control of Acinetobacter baumannii in health care facilities. Clin. Infect. Dis. 42:692-699.
7. Gaddy JA, Tomaras AP, Actis LA. 2009. The Acinetobacter baumannii 19606 OmpA protein plays a role in biofilm formation on abiotic surfaces and in the interaction of this pathogen with eukaryotic cells. Infect. Immun. 77:3150-3160.
8. Hamouda T, Myc A, Donovan B, Shih AY, Reuter JD, Baker JR, Jr. 2001. A novel surfactant nanoemulsion with a unique non-irritant topical antimicrobial activity against bacteria, enveloped viruses and fungi. Microbiol. Res. 156:1-7.
9. Hamouda T, Baker JR, Jr. 2000. Antimicrobial mechanism of action of surfactant lipid preparations in enteric Gram-negative bacilli. J. Appl. Microbiol. 89:397-403.
10. Hemmila MR, Mattar A, Taddonio MA, Arbabi S, Hamouda T, Ward PA, Wang SC, Baker JR, Jr. 2010. Topical nanoemulsion therapy reduces bacterial wound infection and inflammation after burn injury. Surgery 148:499-509.
11. Ioannou CJ, Hanlon GW, Denyer SP. 2007. Action of disinfectant quaternary ammonium compounds against Staphylococcus aureus. Antimicrob. Agents Chemother. 51:296-306.
12. Maurer N, Wong KF, Stark H, Louie L, McIntosh D, Wong T, Scherrer P, Semple SC, Cullis PR. 2001. Spontaneous entrapment of polynucleotides upon electrostatic interaction with ethanol-destabilized cationic liposomes. Biophys. J. 80:2310-2326.
13. Milillo SR, Martin E, Muthaiyan A, Ricke SC. 2011. Immediate reduction of Salmonella enterica serotype Typhimurium viability via membrane destabilization following exposure to multiple-hurdle treatments with heated, acidified organic acid salt solutions. Appl. Environ. Microbiol. 77:3765-3772.
14. Stuart TL, Mulvey M, Simor AE, Tien HC, Battad A, Taylor G, Vayalumkal JV, Weir C, Ofner M, Gravel D, Paton S. 2007. Acinetobacter baumannii in casualties returning from Afghanistan. Can. J. Infect. Control. 22:152-154.
15. Baker JR, Jr, Hamouda T, Shih A, Myc A. January 2003. U.S. patent no. 6506803.
16. Araujo JC, Teran FC, Oliveira RA, Nour EA, Montenegro MA, Campos JR, Vazoller RF. 2003. Comparison of hexamethyldisilazane and critical point drying treatments for SEM analysis of anaerobic biofilms and granular sludge. J. Electron. Microsc. (Tokyo) 52:429-433.
17. Ramage G, Saville SP, Wickes BL, Lopez-Ribot JL. 2002. Inhibition of Candida albicans biofilm formation by farnesol, a quorum-sensing molecule. Appl. Environ. Microbiol. 68:5459-5463.
18. U. S. Department of Defense. 2000. Department of Defense test method standard for environmental engineering considerations and laboratory tests. Document MIL-STD-810F. U.S. Department of Defense, Washington, D. C.
19. Bienek DR, Biagini RE, Charlton DG, Smith JP, Sammons DL, Robertson SA. 2008. Rapid point-of-care test to detect broad ranges of protective antigen-specific immunoglobulinGconcentrations in recipients of the U.S.-licensed anthrax vaccine. Clin. Vaccine Immunol. 15:644-649.
20. Mah TF, O'Toole GA. 2001. Mechanisms of biofilm resistance to antimicrobial agents. Trends Microbiol. 9:34-39.
21. Hujer KM, Hujer AM, Hulten EA, Bajaksouzian S, Adams JM, Donskey CJ, Ecker DJ, Massire Eshoo CMW, Sampath R, Thomson JM, Rather PN, Craft DW, Fishbain JT, Ewell AJ, Jacobs MR, Paterson DL, Bonomo RA. 2006. Analysis of antibiotic resistance genes in multidrugresistant Acinetobacter sp. isolates from military and civilian patients treated at the Walter Reed Army Medical Center. Antimicrob. Agents Chemother. 50:4114-4123.
22. Towner KJ. 2009. Acinetobacter: an old friend, but a new enemy. J. Hosp. Infect. 73:355-363.
23. Gaddy JA, Actis LA. 2009. Regulation of Acinetobacter baumannii biofilm formation. Future Microbiol. 4:273-278.
24. Mihu MR, Sandkovsky U, Han G, Friedman JM, Nosanchuk JD, Martinez LR. 2010. The use of nitric oxide releasing nanoparticles as a treatment against Acinetobacter baumannii in wound infections. Virulence 1:62-67.
25. Dai T, Tegos GP, Lu Z, Huang L, Zhiyentayev T, Franklin MJ, Baer DG, Hamblin MR. 2009. Photodynamic therapy for Acinetobacter baumannii burn infections in mice. Antimicrob. Agents Chemother. 53:3929-3934.
26. DeLeon K, Balldin F, Watters C, Hamood A, Griswold J, Sreedharan S, Rumbaugh KP. 2009. Gallium maltolate treatment eradicates Pseudomonas aeruginosa infection in thermally injured mice. Antimicrob. Agents Chemother. 53:1331-1337.
27. Myc A, Vanhecke T, Landers JJ, Hamouda T, Baker JR, Jr. 2002. The fungicidal activity of novel nanoemulsion (X8W60PC) against clinically important yeast and filamentous fungi. Mycopathologia 155:195-201.
28. Donovan BW, Reuter JD, Cao Z, Myc A, Johnson KJ, Baker JR, Jr. 2000. Prevention of murine influenza A virus pneumonitis by surfactant nanoemulsions. Antivir. Chem. Chemother. 11:41-49.
29. Denyer SP, Stewart GSAB. 1998. Mechanisms of action of disinfectants. Int. Biodeter. Biodegr. 41:261-268.
30. Olsson J, Glantz PO. 1977. Effect of pH and counter ions on the zetapotential of oral streptococci. Arch. Oral Biol. 22:461-466.
31. Lim K, Mustapha A. 2007. Inhibition of Escherichia coli O157:H7, Listeria monocytogenes and Staphylococcus aureus on sliced roast beef by cetylpyridinium chloride and acidified sodium chlorite. Food Microbiol. 24:89-94.
32. Musk DJ, Jr, Hergenrother PJ. 2006. Chemical countermeasures for the control of bacterial biofilms: effective compounds and promising targets. Curr. Med. Chem. 13:2163-2177.
33. Rogers SA, Huigens RW, III, Cavanagh J, Melander C. 2010. Synergistic effects between conventional antibiotics and 2-aminoimidazole-derived antibiofilm agents. Antimicrob. Agents Chemother. 54:2112-2118.
34. Karthikeyan R, Amaechi BT, Rawls HR, Lee VA. 2011. Antimicrobial activity of nanoemulsion on cariogenic Streptococcus mutans. Arch. Oral Biol. 56:437-445.
35. Teixeira PC, Leite GM, Domingues RJ, Silva J, Gibbs PA, Ferreira JP. 2007. Antimicrobial effects of a microemulsion and a nanoemulsion on enteric and other pathogens and biofilms. Int. J. Food Microbiol. 118:15-19.