A novel surfactant nanoemulsion with a unique non-irritant topical antimicrobial activity against bacteria, enveloped viruses and fungi

Microbiological Research

Volumn 156, Issue 1, 2001, Pages 1-7

  Hamouda, Tarek ^a   Myc, Andrzej ^a   Donovan, Brian ^a   Shih, Amy Y ^a   Reuter, Jon D ^a,b   Baker Jr , James R ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b YALE UNIVERSITY   (United States)

Author keywords

Bactericidal; Emulsion; Fungistatic; Nanoemulsion; Virucidal

Indexed keywords

ANTIVIRUS AGENT; BACILLUS CEREUS; BACILLUS SUBTILIS; BACTERICIDAL ACTIVITY; BIOCIDE; CANDIDA ALBICANS; HAEMOPHILUS INFLUENZAE; HERPES SIMPLEX VIRUS 1; INFLUENZA VIRUS A; MICROBIOLOGY; MICROEMULSION; NEISSERIA GONORRHOEAE; STREPTOCOCCUS PNEUMONIAE; SURFACTANT; VACCINIA; VIBRIO CHOLERAE;

EID: 0035001751     PISSN: 09445013     EISSN: None     Source Type: Journal    
DOI: 10.1078/0944-5013-00069     Document Type: Article

References (31)

1. Baker Jr., J. R., Wright, D. C., Hayes, M. M., Hamouda, T., Brisker, J. (2000): Method for inactivating bacteria including bacterial spores. U. S. Patent # 6,015,832.
2. Bundgaard-Nielsen, K., Nielsen, P. V. (1996): Fungicidal effect of 15 disinfectants against 25 fungal contaminants commonly found in bread and cheese manufacturing. J. Food Prot. 59, 268-275.
3. Cassone, A. (1986): Cell wall of pathogenic yeasts and implications for antimycotic therapy. Drugs Exp. Clin. Res. 12, 635-643.
4. Chatlynne, L. G., Brisker, J., Wright, D. C. (1996): A lipid emulsion with effective virucidal activity against HIV-1 and other common viruses. In: Program and Abstracts of the 3rd Conference on Retroviruses and Opportunistic Infections, Foundation for Retrovirology and Human Health, Washington, D. C.
5. Devlin, H. R. (1998): Bacteria for the nineties. Ostomy Wound Manage. 44, 32-40.
6. Donovan, B. W., Reuter, J. D., Cao, Z., Myc, A., Kent, J., Baker Jr., J. R. (2000): Prevention of murine influenza A virus pneumonitis by surfactant nano-emulsions. Antivir. Chem. Chemother. 11, 41-49.
7. Eady, E. A., Cove, J. H. (1990): Topical antibiotic therapy: current status and future prospects. Drugs Exp. Clin. Res. 16, 423-433.
8. File Jr., T. M. (1990): Overview of resistance in the 1990s. Chest 115, 3 S-8 S.
9. Florence, A.T. (1993): Nonionic surfactant vesicles: Preperation and characterization. In: Liposome Technology, (Ed. Gregoriadis, G.). CRC Press, Boca Raton, Florida, 157-176.
10. Gonzales, R., Sande, M. (1995): What will it take to stop physicians from prescribing antibiotics in acute bronchitis? [see comments]. Lancet 345, 665-666.
11. Graybill, J. R., Bocanegra, R., Luther, M. (1995): Antifungal combination therapy with granulocyte colony-stimulating factor and fluconazole in experimental disseminated candidiasis. Eur. J. Clin. Microbiol. Infect. Dis. 14, 700-703.
12. Gregoriadis, G., Florence, A. T. (1993): Liposomes in drug delivery. Clinical, diagnostic and ophthalmic potential. Drugs 45, 15-28.
13. Hamouda, T., Baker Jr., J. R. (2000): Antimicrobial mechanism of action of surfactant lipid preparations in enteric Gram-negative bacilli. J. Appl. Microbiol. 89, 397-403.
14. Hamouda, T., Hayes, M. M., Cao, Z., Tonda, R., Johnson, K., Wright, D. C., Brisker, J., Baker Jr., J. R. (1999): A novel surfactant nanoemulsion with broad-spectrum sporicidal activity against Bacillus species. J. Inf. Dis. 180, 1939-1949.
15. Harkaway, K. S., McGinley, K. J., Foglia, A. N., Lee, W. L., Fried, F., Shalita, A. R., Leyden, J. J. (1992): Antibiotic resistance patterns in coagulase-negative staphylococci after treatment with topical erythromycin, benzoyl peroxide, and combination therapy. Br. J. Dermatol. 126, 586-590.
16. Heir, E., Sundheim, G., Holck, A. L. (1999): Identification and characterization of quaternary ammonium compound resistant staphylococci from the food industry. Int. J. Food. Microbiol. 48, 211-219.
17. Hendrichson, D. A., Krenz, M. M. (1991): Reagents and stains. In: Manual of Clinical Microbiology, (Eds: Balows, A., Hausler Jr., W. J., Herrmann, K. L., Isenberg, H. D., Shadomy, H. J.), American Society for Microbiology, Washington D. C. 1296.
18. Hennessy, D. R. (1994): The disposition of antiparasitic drugs in relation to the development of resistance by parasites of livestock. Acta. Trop. 56, 125-141.
19. Hiom, S. J., Furr, J. R., Russell, A. D., Hann, A. C. (1996): The possible role of yeast cell walls in modifying cellular response to chlorhexidine diacetate, Cytobios. 86, 123-135.
20. Lim, K., Chae, C. B. (1989): A simple assay for DNA transfection by incubation of the cells in culture dishes with substrates for beta-galactosidase. Biotechniques 7, 576-579.
21. Lineaweaver, W., Howard, R., Soucy, D., McMorris, S., Freeman, J., Crain, C., Robertson, J., Rumley, T. (1985): Topical antimicrobial toxicity. Arch. Surg. 120, 267-270.
22. McDonnell, G., Russell, A.D. (1999): Antiseptics and disinfectants: activity, action, and resistance. Clin. Microbiol. Rev. 12, 147-179.
23. Morse, S. S. (1995): Factors in the emergence of infectious diseases. Emerg. Infect. Dis. 1, 7-15.
24. Okeke, I. N., Lamikanra, A., Edelman, R. (1999): Socioeconomic and behavioral factors leading to acquired bacterial resistance to antibiotics in developing countries. Emerg. Infect. Dis. 5, 18-27.
25. Rao, G. G. (1998): Risk factors for the spread of antibiotic-resistant bacteria. Drugs 55, 323-330.
26. Riley, L. W. (1993): Drug-resistant tuberculosis. Clin. Infect. Dis. 17 Suppl. 2, S442-S446.
27. Russell, A.D., Day, M. J. (1993): Antibacterial activity of chlorhexidine. J. Hosp. Infect. 25, 229-238.
28. Rutala, W. A., Weber, D. J. (1997): Uses of inorganic hypochlorite (bleach) in health-care facilities. Clin. Microbiol. Rev. 10, 597-610.
29. Tenover, F. C., Hughes, J. M. (1996): The challenges of emerging infectious diseases. Development and spread of multiply-resistant bacterial pathogens. J. A. M. A. 275, 300-304.
30. Vaara, M. (1993): Outer membrane permeability barrier to azithchromycin, clarithromycin, and roxithromycin in gram-negative enteric bacteria. Antimicrob. Agents Chemother. 37, 354-356.
31. Wasan, K. M., Lopez-Berestein, G. (1995): The past, present, and future uses of liposomes in treating infectious diseases. Immunopharmacol. Immunotoxical. 17, 1-15.