Structure-function studies of claudin extracellular domains by cysteine-scanning mutagenesis

Journal of Biological Chemistry

Volumn 284, Issue 42, 2009, Pages 29205-29217

  Angelow, Susanne ^a   Yu, Alan S L ^a,b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID RESIDUES; BENZENESULFONIC ACID; CLAUDIN; CYSTEINE-SCANNING; CYSTEINE-SCANNING MUTAGENESIS; DIFFERENT SIZES; DISULFIDE BONDING; EXTRACELLULAR DOMAINS; EXTRACELLULAR LOOPS; INORGANIC IONS; ION PERMEATION; ION SELECTIVITY; MADIN-DARBY CANINE KIDNEYS; METHANETHIOSULFONATE; MULTIMERIC; ORGANIC MERCURY; PROTEIN SURFACE; PROTEIN-PROTEIN INTERFACE; RATE OF REACTION; SIZE SELECTIVITY; SMALL MOLECULES; STRUCTURAL BASIS; STRUCTURE-FUNCTION STUDIES; TIGHT JUNCTIONS; TRANSFECTED CELLS; WILD TYPES;

AMINES; AMINO ACIDS; BIOPHYSICS; MERCURY (METAL); OLIGOMERS; ORGANIC ACIDS;

IONS;

AMINO ACID; ASPARTIC ACID; CHLOROMERCURIBENZENESULFONIC ACID; CLAUDIN 2; CYSTEINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DISULFIDE BOND; GENE MUTATION; GENETIC TRANSFECTION; ION TRANSPORT; MUTAGENESIS; NONHUMAN; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; WILD TYPE;

ANIMALS; BIOTINYLATION; CALCIUM; CELL LINE; CYSTEINE; DOGS; ELECTROPHYSIOLOGY; MEMBRANE PROTEINS; MUTAGENESIS; MUTATION; PERMEABILITY; PROTEIN STRUCTURE, TERTIARY; STATIC ELECTRICITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 70350399482     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.043752     Document Type: Article

References (34)

1. Furuse, M., Fujita, K., Hiiragi, T., Fujimoto, K., and Tsukita, S. (1998) J. Cell Biol. 141, 1539-1550
2. Tsukita, S., and Furuse, M. (2000) J. Cell Biol. 149, 13-16
3. Van Itallie, C. M., and Anderson, J. M. (2006) Annu. Rev. Physiol. 68, 403-429
4. Van Itallie, C. M., Holmes, J., Bridges, A., Gookin, J. L., Coccaro, M. R., Proctor, W., Colegio, O. R., and Anderson, J. M. (2008) J. Cell Sci. 121, 298-305
5. Yu, A. S., Cheng, M. H., Angelow, S., Gunzel, D., Kanzawa, S. A., Schneeberger, E. E., Fromm, M., and Coalson, R. D. (2009) J. Gen. Physiol. 133, 111-127
6. Colegio, O. R., Van Itallie, C. M., McCrea, H. J., Rahner, C., and Anderson, J. M. (2002) Am. J. Physiol. Cell Physiol. 283, C142-C147
7. Van Itallie, C. M., Rogan, S., Yu, A., Vidal, L. S., Holmes, J., and Anderson, J. M. (2006) Am. J. Physiol. Renal Physiol. 291, F1288-F1299
8. Alexandre, M. D., Jeansonne, B. G., Renegar, R. H., Tatum, R., and Chen, Y. H. (2007) Biochem. Biophys. Res. Commun. 357, 87-91
9. Blasig, I. E., Winkler, L., Lassowski, B., Mueller, S. L., Zuleger, N., Krause, E., Krause, G., Gast, K., Kolbe, M., and Piontek, J. (2006) Cell Mol. Life Sci. 63, 505-514
10. Daugherty, B. L., Ward, C., Smith, T., Ritzenthaler, J. D., and Koval, M. (2007) J. Biol. Chem. 282, 30005-30013
11. Piontek, J., Winkler, L., Wolburg, H., Müller, S. L., Zuleger, N., Piehl, C., Wiesner, B., Krause, G., and Blasig, I. E. (2008) FASEB J. 22, 146-158
12. Enck, A. H., Berger, U. V., and Yu, A. S. (2001) Am. J. Physiol. Renal Physiol. 281, F966-F974
13. Furuse, M., Furuse, K., Sasaki, H., and Tsukita, S. (2001) J. Cell Biol. 153, 263-272
14. Amasheh, S., Meiri, N., Gitter, A. H., Schoneberg, T., Mankertz, J., Schulzke, J. D., and Fromm, M. (2002) J. Cell Sci. 115, 4969-4976
15. Akabas, M. H., Stauffer, D. A., Xu, M., and Karlin, A. (1992) Science 258, 307-310
16. Karlin, A., and Akabas, M. H. (1998) Methods Enzymol. 293, 123-145
17. Yu, A. S., Enck, A. H., Lencer, W. I., and Schneeberger, E. E. (2003) J. Biol. Chem. 278, 17350-17359
18. Angelow, S., El-Husseini, R., Kanzawa, S. A., and Yu, A. S. (2007) Am. J. Physiol. Renal. Physiol. 293, F166-77
19. Angelow, S., Kim, K. J., and Yu, A. S. (2006) J. Physiol. 571, 15-26
20. Kimizuka, H., and Koketsu, K. (1964) J. Theor. Biol. 6, 290-305
21. Stauffer, D. A., and Karlin, A. (1994) Biochemistry 33, 6840-6849
22. Konrad, M., Schaller, A., Seelow, D., Pandey, A. V., Waldegger, S., Lesslauer, A., Vitzthum, H., Suzuki, Y., Luk, J. M., Becker, C., Schlingmann, K. P., Schmid, M., Rodriguez-Soriano, J., Ariceta, G., Cano, F., Enriquez, R., Juppner, H., Bakkaloglu, S. A., Hediger, M. A., Gallati, S., Neuhauss, S. C., Nurnberg, P., and Weber, S. (2006) Am. J. Hum. Genet. 79, 949-957
23. Eisenman, G., and Horn, R. (1983) J. Membr. Biol. 76, 197-225
24. Diamond, J. M., and Wright, E. M. (1969) Annu. Rev. Physiol. 31, 581-646
25. Moreno, J. H., and Diamond, J. M. (1975) J. Membr. Biol. 21, 197-259
26. Green, W. N., and Andersen, O. S. (1991) Annu. Rev. Physiol. 53, 341-359
27. Hou, J., Paul, D. L., and Goodenough, D. A. (2005) J. Cell Sci. 118, 5109-5118
28. Nagamori, S., Nishiyama, K., and Tokuda, H. (2000) J. Biochem. 128, 129-137
29. Guo, W., Shi, L., and Javitch, J. A. (2003) J. Biol. Chem. 278, 4385-4388
30. Coyne, C. B., Gambling, T. M., Boucher, R. C., Carson, J. L., and Johnson, L. G. (2003) Am. J. Physiol. Lung Cell Mol. Physiol. 285, L1166-L1178
31. Mitic, L. L., Unger, V. M., and Anderson, J. M. (2003) Protein Sci. 12, 218-227
32. Careaga, C. L., and Falke, J. J. (1992) J. Mol. Biol. 226, 1219-1235
33. Xu, M., and Akabas, M. H. (1996) J. Gen. Physiol. 107, 195-205
34. Zhou, X. W., Pfahnl, A., Werner, R., Hudder, A., Llanes, A., Luebke, A., and Dahl, G. (1997) Biophys. J. 72, 1946-1953