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Volumn 15, Issue 4, 2013, Pages 503-507

Effects of Korean ginseng berry extract (GB0710) on penile erection: Evidence from in vitro and in vivo studies

Author keywords

corpus cavernosum; erectile dysfunction (ED); ginseng berry; nitric oxide (NO); smooth muscle

Indexed keywords

GB 0710; GINSENG EXTRACT; NITRIC OXIDE; UNCLASSIFIED DRUG;

EID: 84880119006     PISSN: 1008682X     EISSN: 17457262     Source Type: Journal    
DOI: 10.1038/aja.2013.49     Document Type: Article
Times cited : (30)

References (25)
  • 1
    • 0028036149 scopus 로고
    • Impotence and its medical and psychosocial correlates: Results o. The Massachusetts Male Aging Study
    • Feldman HA, Goldstein I, Hatzichristou DG, Krane RJ, McKinlay JB. Impotence and its medical and psychosocial correlates: results o. The Massachusetts Male Aging Study. J Urol 1994; 151: 54-61.
    • (1994) J Urol , vol.151 , pp. 54-61
    • Feldman, H.A.1    Goldstein, I.2    Hatzichristou, D.G.3    Krane, R.J.4    McKinlay, J.B.5
  • 2
    • 20444461230 scopus 로고    scopus 로고
    • Oxidative stress in arteriogenic erectile dysfunction: Prophylactic role of antioxidants
    • Azadzoi KM, Schulman RN, Aviram M, Siroky MB. Oxidative stress in arteriogenic erectile dysfunction: prophylactic role of antioxidants. J Urol 2005; 174: 386-93.
    • (2005) J Urol , vol.174 , pp. 386-393
    • Azadzoi, K.M.1    Schulman, R.N.2    Aviram, M.3    Siroky, M.B.4
  • 3
    • 33845332378 scopus 로고    scopus 로고
    • Pathophysiology and treatment of diabetic erectile dysfunction
    • Moore CR, Wang R. Pathophysiology and treatment of diabetic erectile dysfunction. Asian J Androl 2006; 8: 675-84.
    • (2006) Asian J Androl , vol.8 , pp. 675-684
    • Moore, C.R.1    Wang, R.2
  • 4
    • 0033838564 scopus 로고    scopus 로고
    • Ginsenoside-induced relaxation of human bronchial smooth muscle via release of nitric oxide
    • Tamaoki J, Nakata J, Kawatani K, Tagaya E, Nagai A. Ginsenoside-induced relaxation of human bronchial smooth muscle via release of nitric oxide. Br J Pharmacol 2000; 130: 1859-64.
    • (2000) Br J Pharmacol , vol.130 , pp. 1859-1864
    • Tamaoki, J.1    Nakata, J.2    Kawatani, K.3    Tagaya, E.4    Nagai, A.5
  • 5
    • 0031932102 scopus 로고    scopus 로고
    • Effect of Korean red ginseng o. The rabbit corpus cavernosal smooth muscle
    • Choi YD, Xin ZC, Choi HK. Effect of Korean red ginseng o. The rabbit corpus cavernosal smooth muscle. Int J Impot Res 1998; 10: 37-43.
    • (1998) Int J Impot Res , vol.10 , pp. 37-43
    • Choi, Y.D.1    Xin, Z.C.2    Choi, H.K.3
  • 6
    • 61849085172 scopus 로고    scopus 로고
    • Efficacy and safety of red ginseng extract powder in patients with erectile dysfunction: Multicenter randomized double-blind placebo-controlled study
    • Ham WS, Kim WT, Lee JS, Ju HJ, Kang SJ et al. [Efficacy and Safety of Red Ginseng Extract Powder in Patients with Erectile Dysfunction: Multicenter, Randomized, Double-Blind, Placebo-Controlled Study]. Korean J Urol 2009; 50: 159-64.
    • (2009) Korean J Urol , vol.50 , pp. 159-164
    • Ham, W.S.1    Kim, W.T.2    Lee, J.S.3    Ju, H.J.4    Kang, S.J.5
  • 7
    • 80052761278 scopus 로고    scopus 로고
    • Effects of ginsenoside on largeconductance K(Ca) channels in human corporal smooth muscle cells
    • Sung HH, Chae MR, So I, Jeon JH, Park JK et al. Effects of ginsenoside on largeconductance K(Ca) channels in human corporal smooth muscle cells. Int J Impot Res 2011; 23: 193-9.
    • (2011) Int J Impot Res , vol.23 , pp. 193-199
    • Sung, H.H.1    Chae, M.R.2    So, I.3    Jeon, J.H.4    Park, J.K.5
  • 8
    • 0344549853 scopus 로고    scopus 로고
    • Ginseng pharmacology: Multiple constituents and multiple actions
    • Attele AS, Wu JA, Yuan CS. Ginseng pharmacology: multiple constituents and multiple actions. Biochem Pharmacol 1999; 58: 1685-93.
    • (1999) Biochem Pharmacol , vol.58 , pp. 1685-1693
    • Attele, A.S.1    Wu, J.A.2    Yuan, C.S.3
  • 9
    • 70349573509 scopus 로고    scopus 로고
    • Ginsenoside content of berries and roots of three typical Korean ginseng (Panax ginseng) cultivars
    • Kim YK, Yoo DS, Xu H, Park NI, Kim HH et al. Ginsenoside content of berries and roots of three typical Korean ginseng (Panax ginseng) cultivars. Nat Prod Commun 2009; 4: 903-6.
    • (2009) Nat Prod Commun , vol.4 , pp. 903-906
    • Kim, Y.K.1    Yoo, D.S.2    Xu, H.3    Park, N.I.4    Kim, H.H.5
  • 10
    • 84873413767 scopus 로고    scopus 로고
    • Anti-hyperglycemic effect of fermented ginseng in type 2 diabetes mellitus mouse model
    • Jeon WJ, Oh JS, Park MS, Ji GE. Anti-hyperglycemic effect of fermented ginseng in type 2 diabetes mellitus mouse model. Phytother Res 2013; 27: 166-72.
    • (2013) Phytother Res , vol.27 , pp. 166-172
    • Jeon, W.J.1    Oh, J.S.2    Park, M.S.3    Ji, G.E.4
  • 11
    • 0041336976 scopus 로고    scopus 로고
    • Anti-hyperglycemic effects of ginseng: Comparison between root and berry
    • Dey L, Xie JT, Wang A, Wu J, Maleckar SA et al. Anti-hyperglycemic effects of ginseng: comparison between root and berry. Phytomedicine 2003; 10: 600-5.
    • (2003) Phytomedicine , vol.10 , pp. 600-605
    • Dey, L.1    Xie, J.T.2    Wang, A.3    Wu, J.4    Maleckar, S.A.5
  • 12
    • 33847711835 scopus 로고    scopus 로고
    • Mesenchymal stem cells alone or ex vivo gene modified with endothelial nitric oxide synthase reverse ageassociated erectile dysfunction
    • Bivalacqua TJ, Deng W, Kendirci M, Usta MF, Robinson C et al. Mesenchymal stem cells alone or ex vivo gene modified with endothelial nitric oxide synthase reverse ageassociated erectile dysfunction. Am J Physiol Heart Circ Physiol 2007; 292: H1278- 90.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Bivalacqua, T.J.1    Deng, W.2    Kendirci, M.3    Usta, M.F.4    Robinson, C.5
  • 13
    • 80052474687 scopus 로고    scopus 로고
    • Relaxant effect and possible mechanism of 17-nor-subincanadine e in rabbit corpora cavernosa
    • Benvindo OD, Nascimento NR, Santos CF, Fonteles MC, Silveira ER et al. Relaxant effect and possible mechanism of 17-nor-subincanadine E in rabbit corpora cavernosa. Asian J Androl 2011; 13: 747-53.
    • (2011) Asian J Androl , vol.13 , pp. 747-753
    • Benvindo, O.D.1    Nascimento, N.R.2    Santos, C.F.3    Fonteles, M.C.4    Silveira, E.R.5
  • 14
    • 80052501025 scopus 로고    scopus 로고
    • Effects of Ginkgo biloba extracts with mirodenafil o. The relaxation of corpus cavernosal smooth muscle an. The potassium channel activity of corporal smooth muscle cells
    • Kim JJ, Han DH, Lim SH, Kim TH, ChaeMRet al. Effects of Ginkgo biloba extracts with mirodenafil o. The relaxation of corpus cavernosal smooth muscle an. The potassium channel activity of corporal smooth muscle cells. Asian J Androl 2011; 13: 742-6.
    • (2011) Asian J Androl , vol.13 , pp. 742-746
    • Kim, J.J.1    Han, D.H.2    Lim, S.H.3    Kim, T.H.4    Chae, M.R.5
  • 15
    • 0242418211 scopus 로고    scopus 로고
    • A comparative study of Ferula hermonis root extracts and sildenafil on copulatory behaviour of male rats
    • Hadidi KA, Aburjai T, Battah AK. A comparative study of Ferula hermonis root extracts and sildenafil on copulatory behaviour of male rats. Fitoterapia 2003; 74: 242-6.
    • (2003) Fitoterapia , vol.74 , pp. 242-246
    • Hadidi, K.A.1    Aburjai, T.2    Battah, A.K.3
  • 16
    • 84879958938 scopus 로고    scopus 로고
    • Panax ginseng in randomised controlled trials: A systematic review
    • e-pub ahead of print 12 September 2012 doi: 10.1002iptr.4832
    • Shergis JL, Zhang AL, Zhou W, Xue CC. Panax ginseng in randomised controlled trials: a systematic review. Phytother Res; e-pub ahead of print 12 September 2012; doi: 10.1002iptr.4832.
    • Phytother Res
    • Shergis, J.L.1    Zhang, A.L.2    Zhou, W.3    Xue, C.C.4
  • 17
    • 81355127576 scopus 로고    scopus 로고
    • Rise of herbal and traditional medicine in erectile dysfunction management
    • Ho CC, Tan HM. Rise of herbal and traditional medicine in erectile dysfunction management. Curr Urol Rep 2011; 12: 470-8.
    • (2011) Curr Urol Rep , vol.12 , pp. 470-478
    • Ho, C.C.1    Tan, H.M.2
  • 18
  • 19
    • 0036266324 scopus 로고    scopus 로고
    • Antidiabetic effects of Panax ginseng berry extract an. The identification of an effective component
    • Attele AS, Zhou YP, Xie JT, Wu JA, Zhang L et al. Antidiabetic effects of Panax ginseng berry extract an. The identification of an effective component. Diabetes 2002; 51: 1851-8.
    • (2002) Diabetes , vol.51 , pp. 1851-1858
    • Attele, A.S.1    Zhou, Y.P.2    Xie, J.T.3    Wu, J.A.4    Zhang, L.5
  • 20
    • 0345411414 scopus 로고    scopus 로고
    • In vitro and in vivo experimental effect of Korean red ginseng on erection
    • Choi YD, Rha KH, Choi HK. In vitro and in vivo experimental effect of Korean red ginseng on erection. J Urol 1999; 162: 1508-11.
    • (1999) J Urol , vol.162 , pp. 1508-1511
    • Choi, Y.D.1    Rha, K.H.2    Choi, H.K.3
  • 21
    • 0031767771 scopus 로고    scopus 로고
    • The relaxation effects of ginseng saponin in rabbit corporal smooth muscle is it a nitric oxide donor?
    • Kim HJ, Woo DS, Lee G, Kim JJ. The relaxation effects of ginseng saponin in rabbit corporal smooth muscle: is it a nitric oxide donor? Br J Urol 1998; 82: 744-8.
    • (1998) Br J Urol , vol.82 , pp. 744-748
    • Kim, H.J.1    Woo, D.S.2    Lee, G.3    Kim, J.J.4
  • 22
    • 0029055392 scopus 로고
    • Ginsenosides-induced nitric oxide-mediated relaxation o. The rabbit corpus cavernosum
    • Chen X, Lee TJ. Ginsenosides-induced nitric oxide-mediated relaxation o. The rabbit corpus cavernosum. Br J Pharmacol 1995; 115: 15-8.
    • (1995) Br J Pharmacol , vol.115 , pp. 15-18
    • Chen, X.1    Lee, T.J.2
  • 23
    • 0030757369 scopus 로고    scopus 로고
    • Panax ginseng pharmacology: A nitric oxide link?
    • Gillis CN. Panax ginseng pharmacology: a nitric oxide link? Biochem Pharmacol 1997; 54: 1-8.
    • (1997) Biochem Pharmacol , vol.54 , pp. 1-8
    • Gillis, C.N.1
  • 24
    • 15244340258 scopus 로고    scopus 로고
    • Free radical-scavenging activity of Korean red ginseng for erectile dysfunction in non-insulin-dependent diabetes mellitus rats
    • Ryu JK, Lee T, Kim DJ, Park IS, Yoon SM et al. Free radical-scavenging activity of Korean red ginseng for erectile dysfunction in non-insulin-dependent diabetes mellitus rats. Urology 2005; 65: 611-5.
    • (2005) Urology , vol.65 , pp. 611-615
    • Ryu, J.K.1    Lee, T.2    Kim, D.J.3    Park, I.S.4    Yoon, S.M.5
  • 25
    • 84877251436 scopus 로고    scopus 로고
    • Improvement of erectile function by Korean red ginseng (Panax ginseng) in a male rat model of metabolic syndrome
    • Kim SD, Kim YJ, Huh JS, Kim SW, Sohn DW. Improvement of erectile function by Korean red ginseng (Panax ginseng) in a male rat model of metabolic syndrome. Asian J Androl 2013; 15: 395-9.
    • (2013) Asian J Androl , vol.15 , pp. 395-399
    • Kim, S.D.1    Kim, Y.J.2    Huh, J.S.3    Kim, S.W.4    Sohn, D.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.