Proteomic-based identification of multiple pathways underlying n-butylidenephthalide-induced apoptosis in LNCaP human prostate cancer cells

Food and Chemical Toxicology

Volumn 59, Issue , 2013, Pages 281-288

  Pang, Cheng Yoong ^a,b   Chiu, Sheng Chun ^a,f   Harn, Horng Jyh ^c   Zhai, Wei Jun ^a   Lin, Shinn Zong ^d   Yang, Hsueh Hui ^a,e  

^a BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^b TZU CHI UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY BEIGANG HOSPITAL   (Taiwan)

^e TZU CHI COLLEGE OF TECHNOLOGY   (Taiwan)

^f Buddhist Compassion Relief Tzu Chi Foundation   (Taiwan)

Author keywords

Apoptosis; Butylidenephthalide; Cell cycle; LNCaP human prostate cancer; Proteomics

Indexed keywords

ALPHA ENOLASE; APOPTOSIS INDUCING FACTOR; ASPARTATE AMINOTRANSFERASE; CALRETICULIN; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLINE; CYTOCHROME C; ELONGATION FACTOR 1ALPHA; ELONGATION FACTOR 2; FAS LIGAND; FRUCTOSE BISPHOSPHATE ALDOLASE; HEAT SHOCK PROTEIN 90; INITIATION FACTOR 4A; LIPOCORTIN 5; MACROPHAGE MIGRATION INHIBITION FACTOR; N BUTYLIDENEPHTHALIDE; NUCLEOLIN; NUCLEOSIDE DIPHOSPHATE KINASE A; PHOSPHOGLYCERATE KINASE; PHTHALIDE DERIVATIVE; PROHIBITIN; PROTEIN 14 3 3; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RNA BINDING PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; IMAGE ANALYSIS; LIQUID CHROMATOGRAPHY; PROSTATE CANCER; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; TWO DIMENSIONAL GEL ELECTROPHORESIS; UPREGULATION; WESTERN BLOTTING;

2DE; 3-(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE; 3-(4,5-DIMETHYL THIZOL-2-YL)-2,5-DIPHENYL TETRAZOLIUM BROMIDE; ABC; ACETONITRILE; ACN; AMMONIUM BICARBONATE; APOPTOSIS; B-CELL LYMPHOMA 2; BAD; BCL2; BCL2 ANTAGONIST OF CELL DEATH; BP; BUTYLIDENEPHTHALIDE; CCND1; CDC25A; CDK; CELL CYCLE; CELL DIVISION CYCLE 25 HOMOLOG A; CHAPS; CYCLIN D1; CYCLIN DEPENDENT KINASE; DIMETHYL SULFOXIDE; DITHIOLERYTHRITOL; DMSO; DTE; EDTA; ENDOPLASMIC RETICULUM; ER; ETHYLENEDIAMINETETRAACETIC ACID; IEF; IMMOBILIZED PH GRADIENT; IPG; ISOELECTRIC FOCUSING; LC/MS/MS; LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY; LNCAP HUMAN PROSTATE CANCER; MTT; N-BUTYLIDENEPHTHALIDE; NL; NON-LINEAR; PAGE; PANTHER; PBS; PHOSPHATE-BUFFERED SALINE; PI; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROPIDIUM IODIDE; PROTEIN ANALYSIS THROUGH EVOLUTIONARY RELATIONSHIPS; PROTEOMICS; ROSWELL PARK MEMORIAL INSTITUTE; RPMI; SDS; SEARCH TOOL FOR THE RETRIEVAL OF INTERACTING GENES/PROTEINS; SODIUM DODECYL SULFATE; STRING; TBST; TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE (TDT)-MEDIATED DUTP NICK END LABELING, OTHER PROTEINS WHICH ARE NOT MENTIONED ABOVE ARE DENOTED AS THEIR GENE SYMBOLS AS LISTED IN TABLE 2; TRIS-BUFFERED SALINE TWEEN-20; TUNEL; TWO-DIMENSIONAL GEL ELECTROPHORESIS;

ADENOCARCINOMA; ANTIGENS, CD95; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL SURVIVAL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENDOPLASMIC RETICULUM STRESS; G0 PHASE; HUMANS; MALE; MITOCHONDRIA; MODELS, BIOLOGICAL; NEOPLASM PROTEINS; PEPTIDE MAPPING; PHTHALIC ANHYDRIDES; PROSTATIC NEOPLASMS; SIGNAL TRANSDUCTION;

EID: 84880099343     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.05.045     Document Type: Article

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