Fangchinoline induced G1/S arrest by modulating expression of p27, PCNA, and cyclin D in human prostate carcinoma cancer PC3 cells and tumor xenograft

Bioscience, Biotechnology and Biochemistry

Volumn 74, Issue 3, 2010, Pages 488-493

  Wang, Chang Dong ^a   Huang, Jian Guo ^a   Gao, Xuan ^a   Li, Yi ^a   Zhou, Shi Yi ^a   Yan, Xu ^a   Zou, An ^a   Chang, Jun Li ^a   Wang, Yue Sheng ^a   Yang, Guang Xiao ^a   He, Guang Yuan ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Apoptosis; Fangchinoline; Human prostate cancer cell lines (PC3); Prostate cancer; Tumor xenograft

Indexed keywords

ANTI-APOPTOTIC PROTEIN; ANTI-PROLIFERATIVE; ANTIBIOTIC ACTIVITY; ANTIPROLIFERATIVE EFFECT; APOPTOSIS; APOPTOTIC; APOPTOTIC PROTEINS; CASPASE-3; CELL-CYCLE PROGRESSION; DOWN-REGULATION; EXPOSURE-TIME; FANGCHINOLINE; HUMAN PROSTATE; HUMAN PROSTATE CANCER CELLS; IN-VIVO; NUDE MICE; PHASE ARREST; PROLIFERATING CELL NUCLEAR ANTIGENS; PROSTATE CANCER CELLS; PROSTATE CANCERS; SIGNALING PATHWAYS; TIME-DEPENDENT; TUMOR VOLUMES; TUMOR XENOGRAFTS; UP-REGULATION; WESTERN BLOTS;

BIOLOGICAL MATERIALS; BLOOD PRESSURE; CELL CULTURE; CELL DEATH; CELL PROLIFERATION; PROTEINS; TUMORS;

GROWTH KINETICS;

ANTINEOPLASTIC AGENT; BENZYLISOQUINOLINE DERIVATIVE; CASPASE 3; CYCLIN D; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLINE; FANGQUINOLINE; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL; APOPTOSIS; ARTICLE; CARCINOMA; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; HUMAN; MALE; METABOLISM; MOUSE; NUDE MOUSE; PROSTATE TUMOR; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BENZYLISOQUINOLINES; CARCINOMA; CASPASE 3; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN D; CYCLIN-DEPENDENT KINASE INHIBITOR P27; G2 PHASE; HUMANS; MALE; MICE; MICE, NUDE; PROLIFERATING CELL NUCLEAR ANTIGEN; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-BCL-2; S PHASE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS MUSCULUS;

EID: 77950103181     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.90490     Document Type: Article

References (28)

1. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, and Thun MJ, CA Cancer J. Clin., 58, 71-96 (2008)
2. Petrylak DP, Tangen CM, Hussain MHA, Lara PN, Jones JA, Taplin ME, Burch PA, Berry D, Moinpour C, Kohli M, Benson MC, Small EJ, Raghavan D, and Crawford ED, N. Engl. J. Med., 351, 1513-1520 (2004).
3. Fang L-H, Zhang Y-H, and Ku B-S, Phytomedicine, 12, 183-188 (2005).
4. Kim H-S, Zhang Y-H, Oh K-W, and Ahn H-Y, J. Ethno-pharmacol., 58, 117-123 (1997).
5. Kuroda H, Nakazawa S, Katagiri K, Shiratori O, and Kozuka M, Chem. Pharm. Bull., 24, 2413-2420 (1976).
6. Hagiwara M, Satomi A-A, and Nagao T, Eur. J. Pharmacol., 466, 63-71 (2003).
7. Wang G, Lemos J, and Ladecola C, Trends Pharmacol. Sci., 25, 120-123 (2004).
8. Oh S-H and Lee B-H, Biochem. Pharmacol., 66, 725-731 (2003).
9. Meng L-H, Zhang H, Hayward L, Takemura H, Shao R-G, and Pommier Y, Cancer Res., 64, 9086-9092 (2004).
10. Lee JH, Kang GH, Kim KC, Kim KM, Park DI, Choi BT, Kang HS, Lee YT, and Choi YH, Int. J. Oncol., 21, 1239-1244 (2002).
11. Wei J, Liu B, Wang L, Qian X, Ding Y, and Yu L, Cancer Chemother. Pharmacol., 60, 703-711 (2007).
12. Kish JA, Bukkapatnam R, and Palazzo F, Cancer Control, 8, 487-495 (2001).
13. Tan Y, Sun X, Xu M, Tan X, Sasson A, Rashidi B, Han Q, Tan X, Wang X, An Z, Rashidi B, Han Q, Tan X, Wang X, An Z, Sun F-X, and Hoffman RM, Clin. Cancer Res., 5, 2157-2163 (1999).
14. Yun J-M, Kweon M-H, Kwon H, Hwang J-K, and Mukhtar H, Carcinogenesis, 27, 1454-1464 (2006).
15. Jiang JH, Sugimoto Y, Liu SL, Chang HL, Park KY, Kulp SK, and Lin YC, Anticancer Res., 24, 91-100 (2004).
16. Quinn DI, Henshall SM, and Sutherland RL, Eur. J. Cancer, 41, 858-887 (2005).
17. Pavletich NP, J. Mol. Biol., 287, 821-828 (1999).
18. Grana X and Reddy P, Oncogene, 11, 211-219 (1995).
19. Molinari M, Cell Prolif., 33, 261-274 (2000).
20. Kastan MB, Canman CE, and Leonard CJ, Cancer Metastasis Rev., 14, 3-15 (1995).
21. Kastan MB and Bartek J, Nature, 432, 316-323 (2004).
22. Pines J, Biochem. J., 308, 697-711 (1995).
23. Resnitzky D, Gossen M, Bujard H, and Reed S, Mol. Cell. Biol., 14, 1669-1679 (1994).
24. Bartkova J, Lukas J, Strauss M, and Bartek J, Oncogene, 17, 1027-1037 (1998).
25. Takahashi T and Caviness VS, J. Neurocytol., 22, 1096-1102 (1993).
26. Shroff EH, Snyder C, and Chandel NS, Cell Cycle, 6, 807-809 (2007).
27. Reed JC, Semin. Hematol., 34, 9-19 (1997).
28. Hickman JA, Cancer Metastasis Rev., 11, 121-139 (1992).