메뉴 건너뛰기




Volumn 72, Issue , 2013, Pages 29-34

Neutralizing activity and protective immunity to ricin toxin conferred by B subunit (RTB)-specific Fab fragments

Author keywords

Biodefense; Mouse; Neutralizing antibodies; Toxin

Indexed keywords

IMMUNOGLOBULIN FC FRAGMENT; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 24B11; MONOCLONAL ANTIBODY SYLH3; RICIN; UNCLASSIFIED DRUG;

EID: 84880097159     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2013.04.005     Document Type: Article
Times cited : (14)

References (34)
  • 2
    • 0030900254 scopus 로고    scopus 로고
    • Pharmacokinetics of heterologous and homologous immunoglobulin G, F(ab')2 and Fab after intravenous administration in the rat
    • Bazin-Redureau M.I., Renard C.B., Scherrmann J.M. Pharmacokinetics of heterologous and homologous immunoglobulin G, F(ab')2 and Fab after intravenous administration in the rat. J. Pharm. Pharmacol. 1997, 49:277-281.
    • (1997) J. Pharm. Pharmacol. , vol.49 , pp. 277-281
    • Bazin-Redureau, M.I.1    Renard, C.B.2    Scherrmann, J.M.3
  • 3
    • 42949111170 scopus 로고    scopus 로고
    • Anamnestic protective immunity to Bacillus anthracis is antibody mediated but independent of complement and Fc receptors
    • Harvill E.T., Osorio M., Loving C.L., Lee G.M., Kelly V.K., Merkel T.J. Anamnestic protective immunity to Bacillus anthracis is antibody mediated but independent of complement and Fc receptors. Infect. Immun. 2008, 76:2177-2182.
    • (2008) Infect. Immun. , vol.76 , pp. 2177-2182
    • Harvill, E.T.1    Osorio, M.2    Loving, C.L.3    Lee, G.M.4    Kelly, V.K.5    Merkel, T.J.6
  • 5
    • 33747204361 scopus 로고    scopus 로고
    • Botulinum type A toxin neutralisation by specific IgG and its fragments: a comparison of mouse systemic toxicity and local flaccid paralysis assays
    • Jones R.G., Alsop T.A., Hull R., Tierney R., Rigsby P., Holley J., Sesardic D. Botulinum type A toxin neutralisation by specific IgG and its fragments: a comparison of mouse systemic toxicity and local flaccid paralysis assays. Toxicon 2006, 48:246-254.
    • (2006) Toxicon , vol.48 , pp. 246-254
    • Jones, R.G.1    Alsop, T.A.2    Hull, R.3    Tierney, R.4    Rigsby, P.5    Holley, J.6    Sesardic, D.7
  • 8
    • 2442626550 scopus 로고    scopus 로고
    • Immunological characteristics associated with the protective efficacy of antibodies to ricin
    • Maddaloni M., Cooke C., Wilkinson R., Stout A.V., Eng L., Pincus S.H. Immunological characteristics associated with the protective efficacy of antibodies to ricin. J. Immunol. 2004, 172:6221-6228.
    • (2004) J. Immunol. , vol.172 , pp. 6221-6228
    • Maddaloni, M.1    Cooke, C.2    Wilkinson, R.3    Stout, A.V.4    Eng, L.5    Pincus, S.H.6
  • 10
    • 33646905060 scopus 로고    scopus 로고
    • Characterization of a novel high-affinity monoclonal immunoglobulin G antibody against the ricin B subunit
    • McGuinness C.R., Mantis N.J. Characterization of a novel high-affinity monoclonal immunoglobulin G antibody against the ricin B subunit. Infect. Immun. 2006, 74:3463-3470.
    • (2006) Infect. Immun. , vol.74 , pp. 3463-3470
    • McGuinness, C.R.1    Mantis, N.J.2
  • 13
    • 73449123743 scopus 로고    scopus 로고
    • A monoclonal immunoglobulin G antibody directed against an immunodominant linear epitope on the ricin A chain confers systemic and mucosal immunity to ricin
    • Neal L.M., O'Hara J., Brey R.N., Mantis N.J. A monoclonal immunoglobulin G antibody directed against an immunodominant linear epitope on the ricin A chain confers systemic and mucosal immunity to ricin. Infect. Immun. 2010, 78:552-561.
    • (2010) Infect. Immun. , vol.78 , pp. 552-561
    • Neal, L.M.1    O'Hara, J.2    Brey, R.N.3    Mantis, N.J.4
  • 16
  • 17
    • 84856567770 scopus 로고    scopus 로고
    • Plant-based expression of a partially humanized neutralizing monoclonal IgG directed against an immunodominant epitope on the ricin toxin A subunit
    • O'Hara J.M., Whaley K., Pauly M., Zeitlin L., Mantis N.J. Plant-based expression of a partially humanized neutralizing monoclonal IgG directed against an immunodominant epitope on the ricin toxin A subunit. Vaccine 2012, 30:1239-1243.
    • (2012) Vaccine , vol.30 , pp. 1239-1243
    • O'Hara, J.M.1    Whaley, K.2    Pauly, M.3    Zeitlin, L.4    Mantis, N.J.5
  • 18
    • 84857812737 scopus 로고    scopus 로고
    • Immunity to ricin: fundamental insights into toxin-antibody interactions
    • O'Hara J.M., Yermakova A., Mantis N.J. Immunity to ricin: fundamental insights into toxin-antibody interactions. Curr. Top. Microbiol. Immunol. 2012, 357:209-241.
    • (2012) Curr. Top. Microbiol. Immunol. , vol.357 , pp. 209-241
    • O'Hara, J.M.1    Yermakova, A.2    Mantis, N.J.3
  • 19
    • 0036956623 scopus 로고    scopus 로고
    • Identification of hypoglycemia in mice as a surrogate marker of ricin toxicosis
    • Pincus S.H., Eng L., Cooke C.L., Maddaloni M. Identification of hypoglycemia in mice as a surrogate marker of ricin toxicosis. Comp. Med. 2002, 52:530-533.
    • (2002) Comp. Med. , vol.52 , pp. 530-533
    • Pincus, S.H.1    Eng, L.2    Cooke, C.L.3    Maddaloni, M.4
  • 20
    • 54949121317 scopus 로고    scopus 로고
    • Post-exposure targeting of specific epitopes on ricin toxin abrogates toxin-induced hypoglycemia, hepatic injury, and lethality in a mouse model
    • Roche J.K., Stone M.K., Gross L.K., Lindner M., Seaner R., Pincus S.H., Obrig T.G. Post-exposure targeting of specific epitopes on ricin toxin abrogates toxin-induced hypoglycemia, hepatic injury, and lethality in a mouse model. Lab. Invest. 2008, 88:1178-1191.
    • (2008) Lab. Invest. , vol.88 , pp. 1178-1191
    • Roche, J.K.1    Stone, M.K.2    Gross, L.K.3    Lindner, M.4    Seaner, R.5    Pincus, S.H.6    Obrig, T.G.7
  • 21
    • 0023091105 scopus 로고
    • Structure and evolution of ricin B chain
    • Rutenber E., Ready M., Robertus J.D. Structure and evolution of ricin B chain. Nature 1987, 326:624-626.
    • (1987) Nature , vol.326 , pp. 624-626
    • Rutenber, E.1    Ready, M.2    Robertus, J.D.3
  • 22
    • 0025939115 scopus 로고
    • Structure of ricin B-chain at 2.5 A resolution
    • Rutenber E., Robertus J.D. Structure of ricin B-chain at 2.5 A resolution. Proteins 1991, 10:260-269.
    • (1991) Proteins , vol.10 , pp. 260-269
    • Rutenber, E.1    Robertus, J.D.2
  • 23
    • 0017074398 scopus 로고
    • Kinetics of binding of the toxic lectins abrin and ricin to surface receptors of human cells
    • Sandvig K., Olsnes S., Pihl A. Kinetics of binding of the toxic lectins abrin and ricin to surface receptors of human cells. J. Biol. Chem. 1976, 251:3977-3984.
    • (1976) J. Biol. Chem. , vol.251 , pp. 3977-3984
    • Sandvig, K.1    Olsnes, S.2    Pihl, A.3
  • 24
    • 76749160798 scopus 로고    scopus 로고
    • Efficient serum clearance of botulinum neurotoxin achieved using a pool of small antitoxin binding agents
    • Sepulveda J., Mukherjee J., Tzipori S., Simpson L.L., Shoemaker C.B. Efficient serum clearance of botulinum neurotoxin achieved using a pool of small antitoxin binding agents. Infect. Immun. 2010, 78:756-763.
    • (2010) Infect. Immun. , vol.78 , pp. 756-763
    • Sepulveda, J.1    Mukherjee, J.2    Tzipori, S.3    Simpson, L.L.4    Shoemaker, C.B.5
  • 25
    • 84857880542 scopus 로고    scopus 로고
    • How ricin and Shiga toxin reach the cytosol of target cells: retrotranslocation from the endoplasmic reticulum
    • Spooner R.A., Lord J.M. How ricin and Shiga toxin reach the cytosol of target cells: retrotranslocation from the endoplasmic reticulum. Curr. Top. Microbiol. Immunol. 2012, 357:19-40.
    • (2012) Curr. Top. Microbiol. Immunol. , vol.357 , pp. 19-40
    • Spooner, R.A.1    Lord, J.M.2
  • 27
    • 0028997997 scopus 로고
    • Pharmacokinetic aspects of digoxin-specific Fab therapy in the management of digitalis toxicity
    • Ujhelyi M.R., Robert S. Pharmacokinetic aspects of digoxin-specific Fab therapy in the management of digitalis toxicity. Clin. Pharmacokinet. 1995, 28:483-493.
    • (1995) Clin. Pharmacokinet. , vol.28 , pp. 483-493
    • Ujhelyi, M.R.1    Robert, S.2
  • 28
    • 84864055517 scopus 로고    scopus 로고
    • Resolution of two overlapping neutralizing B cell epitopes within a solvent exposed, immunodominant alpha-helix in ricin toxin's enzymatic subunit
    • Vance D.J., Mantis N.J. Resolution of two overlapping neutralizing B cell epitopes within a solvent exposed, immunodominant alpha-helix in ricin toxin's enzymatic subunit. Toxicon 2012, 60:874-877.
    • (2012) Toxicon , vol.60 , pp. 874-877
    • Vance, D.J.1    Mantis, N.J.2
  • 29
    • 70349655887 scopus 로고    scopus 로고
    • Analysis of the Fc gamma receptor-dependent component of neutralization measured by anthrax toxin neutralization assays
    • Verma A., Ngundi M.M., Meade B.D., De Pascalis R., Elkins K.L., Burns D.L. Analysis of the Fc gamma receptor-dependent component of neutralization measured by anthrax toxin neutralization assays. Clin. Vaccine Immunol. 2009, 16:1405-1412.
    • (2009) Clin. Vaccine Immunol. , vol.16 , pp. 1405-1412
    • Verma, A.1    Ngundi, M.M.2    Meade, B.D.3    De Pascalis, R.4    Elkins, K.L.5    Burns, D.L.6
  • 32
    • 80053636763 scopus 로고    scopus 로고
    • Protective immunity to ricin toxin conferred by antibodies against the toxin's binding subunit (RTB)
    • Yermakova A., Mantis N.J. Protective immunity to ricin toxin conferred by antibodies against the toxin's binding subunit (RTB). Vaccine 2011, 29:7925-7935.
    • (2011) Vaccine , vol.29 , pp. 7925-7935
    • Yermakova, A.1    Mantis, N.J.2
  • 33
    • 84866286563 scopus 로고    scopus 로고
    • Sub-domains of ricin's B subunit as targets of toxin neutralizing and non-neutralizing monoclonal antibodies
    • Yermakova A., Vance D.J., Mantis N.J. Sub-domains of ricin's B subunit as targets of toxin neutralizing and non-neutralizing monoclonal antibodies. PLoS One 2012, 7:e44317.
    • (2012) PLoS One , vol.7
    • Yermakova, A.1    Vance, D.J.2    Mantis, N.J.3
  • 34
    • 0018078474 scopus 로고
    • Binding of galactose and lactoseto ricin. Equilibrium studies
    • Zentz C., Frenoy J.P., Bourrillon R. Binding of galactose and lactoseto ricin. Equilibrium studies. Biochim. Biophys. Acta 1978, 536:18-26.
    • (1978) Biochim. Biophys. Acta , vol.536 , pp. 18-26
    • Zentz, C.1    Frenoy, J.P.2    Bourrillon, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.