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Volumn 15, Issue 4, 2013, Pages 455-460

Breast cancer resistance protein (Bcrp) an. The testis - An unexpected turn of events

Author keywords

actin filaments; breast cancer resistant protein; ectoplasmic specialisation; effux drug transporter; germ cells; Sertoli cells; spermatids; spermatogenesis; spermiogenesis; testis

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN;

EID: 84880089590     PISSN: 1008682X     EISSN: 17457262     Source Type: Journal    
DOI: 10.1038/aja.2013.24     Document Type: Review
Times cited : (17)

References (63)
  • 1
    • 13044249156 scopus 로고    scopus 로고
    • A multidrug resistance transporter from human MCF-7 breast cancer cells
    • Doyle LA, Yang W, Abruzzo LV, Krogmann T, Gao Y et al. A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc Natl Acad Sci USA 1998; 95: 15665-70.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15665-15670
    • Doyle, L.A.1    Yang, W.2    Abruzzo, L.V.3    Krogmann, T.4    Gao, Y.5
  • 2
    • 0033518874 scopus 로고    scopus 로고
    • Atypical multidrug resistance: Breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines
    • Ross DD, Yang W, Abruzzo LV, Dalton WS, Schneider E et al. Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines. J Natl Cacer Inst 1999; 91: 429-33.
    • (1999) J Natl Cacer Inst , vol.91 , pp. 429-433
    • Ross, D.D.1    Yang, W.2    Abruzzo, L.V.3    Dalton, W.S.4    Schneider, E.5
  • 3
    • 84858002750 scopus 로고    scopus 로고
    • Role of breast cancer resistance protein (BCRPi ABCG2) in cancer drug resistance
    • Natarajan K, Xie Y, Baer MR, Ross DD. Role of breast cancer resistance protein (BCRPi ABCG2) in cancer drug resistance. Biochem Pharmacol 2012; 83: 1084-103.
    • (2012) Biochem Pharmacol , vol.83 , pp. 1084-1103
    • Natarajan, K.1    Xie, Y.2    Baer, M.R.3    Ross, D.D.4
  • 4
    • 84857974889 scopus 로고    scopus 로고
    • Breast cancer resistance protein (BCRPiABCG2): Its role in multidrug resistance and regulation of its gene expression
    • Nakanishi T, Ross DD. Breast cancer resistance protein (BCRPiABCG2): its role in multidrug resistance and regulation of its gene expression. Chin J Cancer 2012; 31: 73-99
    • (2012) Chin J Cancer , vol.31 , pp. 73-99
    • Nakanishi, T.1    Ross, D.D.2
  • 5
    • 79960771381 scopus 로고    scopus 로고
    • Transporter-mediated drug-drug interactions
    • Muller F, Fromm MF. Transporter-mediated drug-drug interactions. Pharmacogenomics 2011; 12: 1017-37.
    • (2011) Pharmacogenomics , vol.12 , pp. 1017-1037
    • Muller, F.1    Fromm, M.F.2
  • 6
    • 33645830172 scopus 로고
    • A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
    • Juliano RL, Ling V. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim Biophys Acta 1976; 455: 152-62.
    • (1976) Biochim Biophys Acta , vol.455 , pp. 152-162
    • Juliano, R.L.1    Ling, V.2
  • 7
    • 0018566696 scopus 로고
    • Purification of P-glycoprotein from plasma membrane vesicles of Chinese hamster ovary cell mutants with reduced colchicine permeability
    • Riordan JR, Ling V. Purification of P-glycoprotein from plasma membrane vesicles of Chinese hamster ovary cell mutants with reduced colchicine permeability. J BiolChem 1979; 254: 12701-5.
    • (1979) J BiolChem , vol.254 , pp. 12701-12705
    • Riordan, J.R.1    Ling, V.2
  • 9
    • 83455163789 scopus 로고    scopus 로고
    • The blood-testis barrier and its implication inmale contraception
    • Cheng CY, Mruk DD. The blood-testis barrier and its implication inmale contraception. Pharmacol Rev 2012; 64: 16-64.
    • (2012) Pharmacol Rev , vol.64 , pp. 16-64
    • Cheng, C.Y.1    Mruk, D.D.2
  • 10
    • 72749106653 scopus 로고    scopus 로고
    • The complexities of antiretroviral drug-drug interactions: Role of ABC and SLC transporters
    • Kis O, Robillard K, Chan GN, Bendayan R. The complexities of antiretroviral drug-drug interactions: role of ABC and SLC transporters. Trends Pharmacol Sci 2010; 31: 22-35.
    • (2010) Trends Pharmacol Sci , vol.31 , pp. 22-35
    • Kis, O.1    Robillard, K.2    Chan, G.N.3    Bendayan, R.4
  • 11
    • 84934441079 scopus 로고    scopus 로고
    • Drug transporters at brain barriers: Expression and regulation by neurological disorders
    • Ashraf T, Kis O, Banerjee N, Bendayan R. Drug transporters at brain barriers: expression and regulation by neurological disorders. Adv Exp Med Biol 2012; 763: 20-69.
    • (2012) Adv Exp Med Biol , vol.763 , pp. 20-69
    • Ashraf, T.1    Kis, O.2    Banerjee, N.3    Bendayan, R.4
  • 12
    • 80053538365 scopus 로고    scopus 로고
    • Breast cancer resistance protein and Pglycoprotein in brain cancer: Two gatekeepers team up
    • Agarwal S, Hartz AM, Elmquist WF, Bauer B. Breast cancer resistance protein and Pglycoprotein in brain cancer: two gatekeepers team up. Curr Pharm Des 2011; 17: 2793-802.
    • (2011) Curr Pharm des , vol.17 , pp. 2793-2802
    • Agarwal, S.1    Hartz, A.M.2    Elmquist, W.F.3    Bauer, B.4
  • 13
    • 79955824328 scopus 로고    scopus 로고
    • Adjudin, a potential male contraceptive, exerts its effects locally i. The seminifeorus epithelium of mammalian testes
    • Mok KW, Mruk DD, Lie PP, Lui WY, Cheng CY. Adjudin, a potential male contraceptive, exerts its effects locally i. The seminifeorus epithelium of mammalian testes. Reproduction 2011; 141: 571-80.
    • (2011) Reproduction , vol.141 , pp. 571-580
    • Mok, K.W.1    Mruk, D.D.2    Lie, P.P.3    Lui, W.Y.4    Cheng, C.Y.5
  • 14
    • 46949109724 scopus 로고    scopus 로고
    • Anchoring junctions as drug targets: Role in contraceptive development
    • Mruk DD, Silvestrini B, Cheng CY. Anchoring junctions as drug targets: role in contraceptive development. Pharmacol Rev 2008; 60: 146-80.
    • (2008) Pharmacol Rev , vol.60 , pp. 146-180
    • Mruk, D.D.1    Silvestrini, B.2    Cheng, C.Y.3
  • 15
    • 84866753215 scopus 로고    scopus 로고
    • Adjudin disrupts spermatogenesis vi. The action of some unlikely partners: Eps8, Arp2i3 complex, drebrin E, PAR6 and 14-3-3
    • Cheng CY, Lie PP, Wong EW, Mruk DD, Silvestrini B. Adjudin disrupts spermatogenesis vi. The action of some unlikely partners: Eps8, Arp2i3 complex, drebrin E, PAR6 and 14-3-3. Spermatogenesis 2011; 1: 291-7.
    • (2011) Spermatogenesis , vol.1 , pp. 291-297
    • Cheng, C.Y.1    Lie, P.P.2    Wong, E.W.3    Mruk, D.D.4    Silvestrini, B.5
  • 16
    • 23844478817 scopus 로고    scopus 로고
    • AF-2364 [1-(2, 4-dichlorobenzyl)-1H-indazole-3-carbohydrazide] is a potential male contraceptive: A review of recent data
    • Cheng CY, Mruk DD, Silvestrini B, Bonanomi M, Wong CH et al. AF-2364 [1-(2, 4-dichlorobenzyl)-1H-indazole-3-carbohydrazide] is a potential male contraceptive: a review of recent data. Contraception 2005; 72: 251-61.
    • (2005) Contraception , vol.72 , pp. 251-261
    • Cheng, C.Y.1    Mruk, D.D.2    Silvestrini, B.3    Bonanomi, M.4    Wong, C.H.5
  • 17
    • 38349148676 scopus 로고    scopus 로고
    • Delivering non-hormonal contraceptives to men: Advances and obstacles
    • Mruk DD, Cheng CY. Delivering non-hormonal contraceptives to men: advances and obstacles. Trends Biotechnol 2008; 26: 90-9.
    • (2008) Trends Biotechnol , vol.26 , pp. 90-99
    • Mruk, D.D.1    Cheng, C.Y.2
  • 18
    • 83755207358 scopus 로고    scopus 로고
    • P-glycoprotein regulates blood-testis barrier dynamics via its effects o. The occludinizonula occludens 1 (ZO-1) protein complex mediated by focal adhesion kinase (FAK)
    • Su L, Mruk DD, Lui WY, Lee WM, Cheng CY. P-glycoprotein regulates blood-testis barrier dynamics via its effects o. The occludinizonula occludens 1 (ZO-1) protein complex mediated by focal adhesion kinase (FAK). Proc Natl Acad Sci USA 2011; 108: 19623-8.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 19623-19628
    • Su, L.1    Mruk, D.D.2    Lui, W.Y.3    Lee, W.M.4    Cheng, C.Y.5
  • 19
    • 79958187254 scopus 로고    scopus 로고
    • Drug transporters and blood-testis barrier function
    • Su L, Mruk DD, Lee WM, Cheng CY. Drug transporters and blood-testis barrier function. J Endocrinol 2011; 209: 337-51.
    • (2011) J Endocrinol , vol.209 , pp. 337-351
    • Su, L.1    Mruk, D.D.2    Lee, W.M.3    Cheng, C.Y.4
  • 20
    • 4444310389 scopus 로고    scopus 로고
    • HendrikseNHet al. The distribution of drugefflux pumps, P-gp, BCRP,MRP1and MRP2, i. The normal blood-testis barrier and in primary testicular tumours
    • Bart J, Hollema H, Groen HJ, de Vries EG, HendrikseNHet al. The distribution of drugefflux pumps, P-gp, BCRP,MRP1and MRP2, i. The normal blood-testis barrier and in primary testicular tumours. Eur J Cancer 2004; 40: 2064-70.
    • (2004) Eur J Cancer , vol.40 , pp. 2064-2070
    • Bart, J.1    Hollema, H.2    Groen, H.J.3    De Vries, E.G.4
  • 21
    • 84871908157 scopus 로고    scopus 로고
    • Localization of breast cancer resistance protein (Bcrp) in endocrine organs and inhibition of its transport activity by steroid hormones
    • Dankers AC, Sweep FC, Pertijs JC, Verweij V, van den Heuvel JJ et al. Localization of breast cancer resistance protein (Bcrp) in endocrine organs and inhibition of its transport activity by steroid hormones. Cell Tissue Res 2012; 349: 551-63.
    • (2012) Cell Tissue Res , vol.349 , pp. 551-563
    • Dankers, A.C.1    Sweep, F.C.2    Pertijs, J.C.3    Verweij, V.4    Van Den Heuvel, J.J.5
  • 22
    • 79960199294 scopus 로고    scopus 로고
    • The blood-testis barrier: The junctional permeability. The proteins an. The lipids
    • Pelletier RM. The blood-testis barrier. The junctional permeability. The proteins an. The lipids. Prog Histochem Cytochem 2011; 46: 49-127.
    • (2011) Prog Histochem Cytochem , vol.46 , pp. 49-127
    • Pelletier, R.M.1
  • 23
    • 84934435062 scopus 로고    scopus 로고
    • Blood-tissue barriers: Morphofunctional and immunological aspects o. The blood-testis and blood- epididymal barriers
    • Franca LR, Auharek SA, Hess RA, Dufour JM, Hinton BT. Blood-tissue barriers: morphofunctional and immunological aspects o. The blood-testis and blood- epididymal barriers. Adv Exp Med Biol 2012; 763: 237-59.
    • (2012) Adv Exp Med Biol , vol.763 , pp. 237-259
    • Franca, L.R.1    Auharek, S.A.2    Hess, R.A.3    Dufour, J.M.4    Hinton, B.T.5
  • 24
    • 84880104603 scopus 로고    scopus 로고
    • Austin, TX: Landes Biosciencei Springer Science1Business Media, LLC
    • Cheng CY. Biology and Regulation of Blood-Tissus Barriers. Austin, TX: Landes BioscienceiSpringer Science1Business Media, LLC; 2012. p1-361.
    • (2012) Biology and Regulation of Blood-Tissus Barriers , pp. 1-361
    • Cheng, C.Y.1
  • 25
    • 39849110870 scopus 로고    scopus 로고
    • Biology and regulation of ectoplasmic specialization, an atypical adherens junction type, i. The testis
    • Wong EW, Mruk DD, Cheng CY. Biology and regulation of ectoplasmic specialization, an atypical adherens junction type, i. The testis. Biochem Biophys Acta 2008; 1778: 692-708.
    • (2008) Biochem Biophys Acta , vol.1778 , pp. 692-708
    • Wong, E.W.1    Mruk, D.D.2    Cheng, C.Y.3
  • 26
    • 33645918999 scopus 로고    scopus 로고
    • The blood-testis barrier: Its biology, regulation and physiological role in spermatogenesis
    • Wong CH, Cheng CY. The blood-testis barrier: Its biology, regulation and physiological role in spermatogenesis. Curr Topics Dev Biol 2005; 71: 263-96.
    • (2005) Curr Topics Dev Biol , vol.71 , pp. 263-296
    • Wong, C.H.1    Cheng, C.Y.2
  • 27
    • 73949108426 scopus 로고    scopus 로고
    • Blood-testis barrier, functional and transport proteins and spermatogenesis
    • Setchell BP. Blood-testis barrier, functional and transport proteins and spermatogenesis. Adv Exp Med Biol 2008; 636: 212-33.
    • (2008) Adv Exp Med Biol , vol.636 , pp. 212-233
    • Setchell, B.P.1
  • 28
    • 0141765289 scopus 로고    scopus 로고
    • Blood-testis barrier
    • Knobil E, Neill J, editors New York Academic Press
    • Setchell B. Blood-testis barrier. In: Knobil E, Neill J, editors. Encyclopedia of Reproduction. New York: Academic Press; 1998. pp375-81.
    • (1998) Encyclopedia of Reproduction , pp. 375-381
    • Setchell, B.1
  • 29
    • 0002236654 scopus 로고
    • Ultrastructure and function o. The Sertoli cell
    • Hamilton D, Greep R, editors Washington, DC: American Physiological Society
    • Fawcett D. Ultrastructure and function o. The Sertoli cell. In: Hamilton D, Greep R, editors. Handbook of Physiology. Washington, DC: American Physiological Society; 1975. p21-5.
    • (1975) Handbook of Physiology , pp. 21-25
    • Fawcett, D.1
  • 30
    • 0014892078 scopus 로고
    • The blood-testis barrier i. The rat an. The physiological compartmentation o. The seminiferous epithelium
    • Dym M, Fawcett DW. The blood-testis barrier i. The rat an. The physiological compartmentation o. The seminiferous epithelium. Biol Reprod 1970; 3: 308-26.
    • (1970) Biol Reprod , vol.3 , pp. 308-326
    • Dym, M.1    Fawcett, D.W.2
  • 31
    • 0014884660 scopus 로고
    • Electron microscopic observations o. The structural components o. The blood-testis barrier
    • Fawcett DW, Leak LV, Heidger PM. Electron microscopic observations o. The structural components o. The blood-testis barrier. J Reprod Fertil 1970; (Suppl 10): 105-22.
    • (1970) J Reprod Fertil , Issue.SUPPL. 10 , pp. 105-122
    • Fawcett, D.W.1    Leak, L.V.2    Heidger, P.M.3
  • 32
    • 0015608073 scopus 로고
    • The fine structure o. The monkey (Macaca) Sertoli cell and its role in maintainin. The blood-testis barrier
    • Dym M. The fine structure o. The monkey (Macaca) Sertoli cell and its role in maintainin. The blood-testis barrier. Anat Rec 1973; 175: 639-56.
    • (1973) Anat Rec , vol.175 , pp. 639-656
    • Dym, M.1
  • 33
    • 84878208730 scopus 로고    scopus 로고
    • Breast cancer resistance protein regulates apical ectoplasmic specialization dynamics stage-specifically i. The rat testis
    • Qian X, Mruk DD, Wong EW, Cheng CY. Breast cancer resistance protein regulates apical ectoplasmic specialization dynamics stage-specifically i. The rat testis. Am J Physiol Endocrinol Metab 2013; 304: E757-69.
    • (2013) Am J Physiol Endocrinol Metab , vol.304
    • Qian, X.1    Mruk, D.D.2    Wong, E.W.3    Cheng, C.Y.4
  • 34
    • 79951778173 scopus 로고    scopus 로고
    • Drug transporters. The blood-testis barrier and spermatogenesis
    • Su L, Mruk DD, Cheng CY. Drug transporters. The blood-testis barrier and spermatogenesis. J Endocrinol 2011; 208: 207-23.
    • (2011) J Endocrinol , vol.208 , pp. 207-223
    • Su, L.1    Mruk, D.D.2    Cheng, C.Y.3
  • 35
    • 79651475092 scopus 로고    scopus 로고
    • Emerging role for drug transporters a. The blood-testis barrier
    • Mruk DD, Su L, Cheng CY. Emerging role for drug transporters a. The blood-testis barrier. Trends Pharmacol Sci 2011; 32: 99-106.
    • (2011) Trends Pharmacol Sci , vol.32 , pp. 99-106
    • Mruk, D.D.1    Su, L.2    Cheng, C.Y.3
  • 36
    • 84867099595 scopus 로고    scopus 로고
    • The bioavailability and distribution of transresveratrol are constrained by ABC transporters
    • Planas JM, Alfaras I, Colom H, Juan ME. The bioavailability and distribution of transresveratrol are constrained by ABC transporters. Arch Biochem Biophys 2012; 527: 67-73.
    • (2012) Arch Biochem Biophys , vol.527 , pp. 67-73
    • Planas, J.M.1    Alfaras, I.2    Colom, H.3    Juan, M.E.4
  • 37
    • 78649648616 scopus 로고    scopus 로고
    • In vitro and in vivo evidence fo. The importance of breast cancer resistance protein transporters (BCRPiMXRiABCPi ABCG2)
    • Meyer ZU Schwabedissen HE, Kroemer HK. In vitro and in vivo evidence fo. The importance of breast cancer resistance protein transporters (BCRPiMXRiABCPi ABCG2). Handb Exp Pharmacol 2011; 201: 325-71.
    • (2011) Handb Exp Pharmacol , vol.201 , pp. 325-371
    • Meyer, Z.U.1    Schwabedissen, H.E.2    Kroemer, H.K.3
  • 38
    • 22344435180 scopus 로고    scopus 로고
    • Regulation o. The cell surface expression of human BCRPiABCG2 b. The phosphorylation state of Akt in polarized cells
    • Takada T, Suzuki H, Gotoh Y, Sugiyama Y. Regulation o. The cell surface expression of human BCRPiABCG2 b. The phosphorylation state of Akt in polarized cells. Drug Metab Disposit 2005; 33: 905-9.
    • (2005) Drug Metab Disposit , vol.33 , pp. 905-909
    • Takada, T.1    Suzuki, H.2    Gotoh, Y.3    Sugiyama, Y.4
  • 39
    • 41249100545 scopus 로고    scopus 로고
    • The 44-kDa Pim-1 kinase phosphorylates BCRPiABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells
    • Xie Y, Xu K, Linn DE, Yang XP, Guo Z et al. The 44-kDa Pim-1 kinase phosphorylates BCRPiABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells. J Biol Chem 2008; 283: 3349-56.
    • (2008) J Biol Chem , vol.283 , pp. 3349-3356
    • Xie, Y.1    Xu, K.2    Linn, D.E.3    Yang, X.P.4    Guo, Z.5
  • 40
    • 44149086662 scopus 로고    scopus 로고
    • Quantitative investigation o. The role of breast cancer resistance protein (BcrpiAbcg2) in limiting brain and testis penetration of xenobiotic compounds
    • Enokizono J, Kusuhara H, Ose A, Schinkel AH, Sugiyama Y. Quantitative investigation o. The role of breast cancer resistance protein (BcrpiAbcg2) in limiting brain and testis penetration of xenobiotic compounds. Drug Metab Disposit 2008; 36: 995-1002.
    • (2008) Drug Metab Disposit , vol.36 , pp. 995-1002
    • Enokizono, J.1    Kusuhara, H.2    Ose, A.3    Schinkel, A.H.4    Sugiyama, Y.5
  • 42
    • 35348846046 scopus 로고    scopus 로고
    • Transcriptional upregulation of breast cancer resistance protein by 17b-estradiol in ERa-positive MCF-7 breast cancer cells
    • Zhang Y, Zhou G, Wang H, Zhang X, Wei F et al. Transcriptional upregulation of breast cancer resistance protein by 17b-estradiol in ERa-positive MCF-7 breast cancer cells. Oncology 2006; 71: 446-55.
    • (2006) Oncology , vol.71 , pp. 446-455
    • Zhang, Y.1    Zhou, G.2    Wang, H.3    Zhang, X.4    Wei, F.5
  • 43
    • 65249154823 scopus 로고    scopus 로고
    • Androgen receptor roles in spermatogenesis and fertility: Lessons from testicular cell-specific androgen receptor knockout mice
    • Wang RS, Yeh S, Tzeng CR, Chang C. Androgen receptor roles in spermatogenesis and fertility: lessons from testicular cell-specific androgen receptor knockout mice. Endocr Rev 2009; 30: 119-32.
    • (2009) Endocr Rev , vol.30 , pp. 119-132
    • Wang, R.S.1    Yeh, S.2    Tzeng, C.R.3    Chang, C.4
  • 46
    • 77954024451 scopus 로고    scopus 로고
    • A local autocrine axis i. The testes that regulates spermatogenesis
    • Cheng CY, Mruk DD. A local autocrine axis i. The testes that regulates spermatogenesis. Nat Rev Endocrinol 2010; 6: 380-95.
    • (2010) Nat Rev Endocrinol , vol.6 , pp. 380-395
    • Cheng, C.Y.1    Mruk, D.D.2
  • 47
    • 0037180446 scopus 로고    scopus 로고
    • The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria
    • Jonker JW, Buitelaar M, Wagenaar E, van der Valk MA, Scheffer GL et al. The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria. Proc Natl Acad Sci USA 2002; 99: 15649-54.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 15649-15654
    • Jonker, J.W.1    Buitelaar, M.2    Wagenaar, E.3    Van Der Valk, M.A.4    Scheffer, G.L.5
  • 48
    • 34748926909 scopus 로고    scopus 로고
    • Effect of breast cancer resistance protein (Bcrpi Abcg2) o. The disposition of phytoestrogens
    • Enokizono J, Kusuhara H, Sugiyama Y. Effect of breast cancer resistance protein (Bcrpi Abcg2) o. The disposition of phytoestrogens. Mol Pharmacol 2007; 72: 967-75.
    • (2007) Mol Pharmacol , vol.72 , pp. 967-975
    • Enokizono, J.1    Kusuhara, H.2    Sugiyama, Y.3
  • 49
    • 0042734626 scopus 로고    scopus 로고
    • Advancing towards a male contraceptive: A novel approach from an unexpected direction
    • Robaire B. Advancing towards a male contraceptive: a novel approach from an unexpected direction. Trends Pharmacol Sci 2003; 24: 326-8.
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 326-328
    • Robaire, B.1
  • 50
    • 0036892223 scopus 로고    scopus 로고
    • Multidrug resistance genes and P-glycoprotein i. The testis o. The rat, mouse, guinea pig, and human
    • Melaine N, Lienard MO, Dorval I, Le Goascogne C, Lejeune H et al. Multidrug resistance genes and P-glycoprotein i. The testis o. The rat, mouse, guinea pig, and human. Biol Reprod 2002; 67: 1699-707.
    • (2002) Biol Reprod , vol.67 , pp. 1699-1707
    • Melaine, N.1    Lienard, M.O.2    Dorval, I.3    Le Goascogne, C.4    Lejeune, H.5
  • 51
    • 70350346593 scopus 로고    scopus 로고
    • Drug transporter, P-glycoprotein (MDR1), is an integrated component o. The mammalian blood-testis barrier
    • Su L, Cheng CY, Mruk DD. Drug transporter, P-glycoprotein (MDR1), is an integrated component o. The mammalian blood-testis barrier. Int J Biochem Cell Biol 2009; 41: 2578-87.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 2578-2587
    • Su, L.1    Cheng, C.Y.2    Mruk, D.D.3
  • 53
    • 0032494133 scopus 로고    scopus 로고
    • Multidrug resistance protein 1 protect. The oropharyngeal mucosal layer an. The testicular tubules against drug-induced damage
    • Wijnholds J, Scheffer GL, van der Valk M, van der Valk P, Beijnen JH et al. Multidrug resistance protein 1 protect. The oropharyngeal mucosal layer an. The testicular tubules against drug-induced damage. J Exp Med 1998; 188: 797-808.
    • (1998) J Exp Med , vol.188 , pp. 797-808
    • Wijnholds, J.1    Scheffer, G.L.2    Van Der Valk, M.3    Van Der Valk, P.4    Beijnen, J.H.5
  • 54
    • 79954549857 scopus 로고    scopus 로고
    • Regulation of spermiogenesis, spermiation and blood-testis barrier dynamics: Novel insights from studies on Eps8 and Arp3
    • Cheng CY, Mruk DD. Regulation of spermiogenesis, spermiation and blood-testis barrier dynamics: novel insights from studies on Eps8 and Arp3. Biochem J 2011; 435: 553-62.
    • (2011) Biochem J , vol.435 , pp. 553-562
    • Cheng, C.Y.1    Mruk, D.D.2
  • 55
    • 84866766147 scopus 로고    scopus 로고
    • Actin binding proteins and spermatogenesis Some unexpected findings
    • Cheng CY, Mruk DD. Actin binding proteins and spermatogenesis. Some unexpected findings. Spermatogenesis 2011; 1: 99-104.
    • (2011) Spermatogenesis , vol.1 , pp. 99-104
    • Cheng, C.Y.1    Mruk, D.D.2
  • 57
    • 0021892796 scopus 로고
    • Sertoli cell junctions: Morphological and functional correlates
    • Russell LD, Peterson RN. Sertoli cell junctions: morphological and functional correlates. Int Rev Cytol 1985; 94: 177-211.
    • (1985) Int Rev Cytol , vol.94 , pp. 177-211
    • Russell, L.D.1    Peterson, R.N.2
  • 58
    • 84873435294 scopus 로고    scopus 로고
    • Focal adhesion proteins zyxin and vinculin are co-distributed at tubulobulbar complexes
    • Young JS, Vogl AW. Focal adhesion proteins zyxin and vinculin are co-distributed at tubulobulbar complexes. Spermatogenesis 2012; 2: 63-8.
    • (2012) Spermatogenesis , vol.2 , pp. 63-68
    • Young, J.S.1    Vogl, A.W.2
  • 59
    • 58149522493 scopus 로고    scopus 로고
    • Cortactin (CTTN), N-WASP (WASL), and clathrin (CLTC) are present at podosome-like tubulobulbar complexes i. The rat testis
    • Young JS, Guttman JA, Vaid KS, Vogl AW. Cortactin (CTTN), N-WASP (WASL), and clathrin (CLTC) are present at podosome-like tubulobulbar complexes i. The rat testis. Biol Reprod 2009; 80: 153-61.
    • (2009) Biol Reprod , vol.80 , pp. 153-161
    • Young, J.S.1    Guttman, J.A.2    Vaid, K.S.3    Vogl, A.W.4
  • 60
    • 58149479748 scopus 로고    scopus 로고
    • Tubulobulbar complexes are intercellular podosome-like structures that internalize intact intercellular junctions during epithelial remodeling events i. The rat testis
    • Young JS, Guttman JA, Vaid KS, Vogl AW. Tubulobulbar complexes are intercellular podosome-like structures that internalize intact intercellular junctions during epithelial remodeling events i. The rat testis. Biol Reprod 2009; 80: 162-74.
    • (2009) Biol Reprod , vol.80 , pp. 162-174
    • Young, J.S.1    Guttman, J.A.2    Vaid, K.S.3    Vogl, A.W.4
  • 61
    • 70349918230 scopus 로고    scopus 로고
    • An intracellular trafficking pathway i. The seminiferous epithelium regulating spermatogenesis: A biochemical and molecular perspective
    • Cheng CY, Mruk DD. An intracellular trafficking pathway i. The seminiferous epithelium regulating spermatogenesis: a biochemical and molecular perspective. Crit Rev Biochem Mol Biol 2009; 44: 245-63.
    • (2009) Crit Rev Biochem Mol Biol , vol.44 , pp. 245-263
    • Cheng, C.Y.1    Mruk, D.D.2
  • 62
    • 84867580115 scopus 로고    scopus 로고
    • Intestinal transporters for endogenic and pharmaceutical organic anions: The challenges of deriving in-vitro kinetic parameters fo. The prediction of clinically relevant drug-drug interactions
    • Grandvuinet AS, Vestergaard HT, Rapin N, Steffansen B. Intestinal transporters for endogenic and pharmaceutical organic anions. The challenges of deriving in-vitro kinetic parameters fo. The prediction of clinically relevant drug-drug interactions. J Pharm Pharmacol 2012; 64: 1523-48.
    • (2012) J Pharm Pharmacol , vol.64 , pp. 1523-1548
    • Grandvuinet, A.S.1    Vestergaard, H.T.2    Rapin, N.3    Steffansen, B.4
  • 63
    • 84866018277 scopus 로고    scopus 로고
    • The role of OATP1B1 and BCRP in pharmacokinetics and DDI of novel statins
    • Hua WJ, Hua WX, Fang JJ. The role of OATP1B1 and BCRP in pharmacokinetics and DDI of novel statins. Cardiovasc Ther 2011; 30: e234-41.
    • (2011) Cardiovasc Ther , vol.30
    • Hua, W.J.1    Hua, W.X.2    Fang, J.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.