An epigenetic antimalarial resistance mechanism involving parasite genes linked to nutrient uptake

Journal of Biological Chemistry

Volumn 288, Issue 27, 2013, Pages 19429-19440

  Sharma, Paresh ^a   Wollenberg, Kurt ^b   Sellers, Morgan ^a   Zainabadi, Kayvan ^a   Galinsky, Kevin ^c   Moss, Eli ^c   Nguitragool, Wang ^a   Neafsey, Daniel ^c   Desai, Sanjay A ^a  

^a Laboratory of Malaria and Vector Research   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL COMPOUNDS; ANTIMALARIAL DRUG; ERYTHROCYTE MEMBRANE; HISTONE MODIFICATION; PLASMODIAL SURFACE ANION CHANNELS; PLASMODIUM FALCIPARUM; RESISTANCE MECHANISMS; TREATMENT FAILURE;

CELL MEMBRANES; MALARIA CONTROL; NUTRIENTS;

GENE EXPRESSION;

ANION CHANNEL; BLASTICIDIN S; DNA; PLASMODIAL SURFACE ANION CHANNEL; UNCLASSIFIED DRUG;

ANTIMALARIAL DRUG RESISTANCE; ARTICLE; CHANNEL GATING; CLAG GENE; CONTROLLED STUDY; EPIGENETICS; ERYTHROCYTE MEMBRANE; GENE; GENE CONTROL; GENE EXPRESSION; GENE SILENCING; HISTONE MODIFICATION; HOST PARASITE INTERACTION; MOUSE; NONHUMAN; NUTRIENT UPTAKE; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION;

ANTIMALARIAL DRUG RESISTANCE; DNA TRANSFORMATION; DRUG RESISTANCE; EPIGENETICS; GENE SILENCING; HOST-PATHOGEN INTERACTIONS; MALARIA; PARASITOLOGY;

ANTIMALARIALS; ANTIPORTERS; CELL ADHESION MOLECULES; DRUG RESISTANCE; ENZYME INHIBITORS; EPIGENESIS, GENETIC; GENES, PROTOZOAN; HUMANS; ION TRANSPORT; MALARIA, FALCIPARUM; NUCLEOSIDES; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS;

EID: 84880079033     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.468371     Document Type: Article

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