The efficient expression of human fibroblast collagenase in Escherichia coli and the discovery of flavonoid inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 28, Issue 4, 2013, Pages 741-746

  Lu, Weiqiang ^a   Zhu, Junsheng ^a   Zou, Shien ^b   Li, Xi ^a   Huang, Jin ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b OBSTETRICS AND GYNECOLOGY HOSPITAL OF FUDAN UNIVERSITY   (China)

Author keywords

Catalytic domain; Flavonoids; MMP 1; Soluble expression

Indexed keywords

APIGENIN; AURANTIIN; CHRYSIN; DAIDZEIN; FISETIN; FLAVONOID; GENISTEIN; HESPERETIN; INTERSTITIAL COLLAGENASE; KAEMPFEROL; LUTEOLIN; MORIN; MYRICETIN; NARINGENIN; PUERARIN; QUERCETIN; QUERCITRIN; RUTOSIDE; TAXIFOLIN;

ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ESCHERICHIA COLI; FIBROBLAST; FLUORESCENCE ANALYSIS; IC 50; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; TEMPERATURE;

CLONING, MOLECULAR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DISCOVERY; ENZYME ACTIVATION; ENZYME INHIBITORS; ESCHERICHIA COLI; FLAVONOIDS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MATRIX METALLOPROTEINASE 8; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84880071256     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756366.2012.681650     Document Type: Article

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