Two salt bridges differentially contribute to the maintenance of cystic fibrosis transmembrane conductance regulator (CFTR) channel function

Journal of Biological Chemistry

Volumn 288, Issue 28, 2013, Pages 20758-20767

  Cui, Guiying ^a   Freeman, Cody S ^a   Knotts, Taylor ^a   Prince, Chengyu Z ^a   Kuang, Christopher ^a   McCarty, Nael A ^a  

^a CHILDREN'S HEALTHCARE OF ATLANTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BI-FUNCTIONAL; CHANNEL FUNCTIONS; CHLORIDE IONS; CONDUCTANCE STATE; CROSSLINKER; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATORS; OPEN PORES; SALT BRIDGES;

AMINO ACIDS;

CHLORINE COMPOUNDS;

1,2 ETHANEDIYL BISMETHANETHIOSULFONIC ACID; ADENOSINE TRIPHOSPHATE; ARGININE; ASPARTIC ACID; CALCIUM CHANNEL L TYPE; CYSTEINE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; MUTANT PROTEIN; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DIMERIZATION; FEMALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TRANSPORT; STRUCTURE ACTIVITY RELATION; XENOPUS LAEVIS;

ABC TRANSPORTER; CFTR; GATING; MTS REAGENTS; OOCYTE; PORE; SALT BRIDGE; XENOPUS;

ADENOSINE TRIPHOSPHATE; ALGORITHMS; AMINO ACID SEQUENCE; ANIMALS; ARGININE; ASPARTIC ACID; BINDING SITES; CHLORIDES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; FEMALE; HUMANS; ION CHANNEL GATING; KINETICS; MEMBRANE POTENTIALS; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; RNA, COMPLEMENTARY; XENOPUS LAEVIS;

EID: 84880065252     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.476226     Document Type: Article

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