In vitro assessment of Macleaya cordata crude extract bioactivity and anticancer properties in normal and cancerous human lung cells

Experimental and Toxicologic Pathology

Volumn 65, Issue 6, 2013, Pages 775-787

  Liu, Min ^a   Lin, Yu ling ^a   Chen, Xuan Ren ^a   Liao, Chi Cheng ^a   Poo, Wak Kim ^a  

^a CHINESE CULTURE UNIVERSITY   (Taiwan)

Author keywords

A549; Anticancer; Cytotoxicity; Human lung cancers; Macleaya cordata; MRC5

Indexed keywords

CYTOTOXIC AGENT; MACLEAYA CORDATA EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL MEMBRANE PERMEABILITY; CELL METABOLISM; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EXPOSURE; EPITHELIUM CELL; FETUS; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; LUNG FIBROBLAST; MACLEAYA CORDATA; PAPAVERACEAE; PLANT LEAF;

A549; ANTICANCER; CYTOTOXICITY; HUMAN LUNG CANCERS; MACLEAYA CORDATA; MRC5;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; FIBROBLASTS; HUMANS; LUNG NEOPLASMS; PAPAVERACEAE;

MACLEAYA CORDATA;

EID: 84880042014     PISSN: 09402993     EISSN: 16181433     Source Type: Journal    
DOI: 10.1016/j.etp.2012.11.004     Document Type: Article

References (66)

1. Adhami V.M., Aziz M.H., Reagan-Shaw S.R., Nihal M., Mukhtar H., Ahmad N. Sanguinarine causes cell cycle blockade and apoptosis of human prostate carcinoma cells via modulation of cyclin kinase inhibitor-cyclin-cyclin-dependent kinase machinery. Molecular Cancer Therapeutics 2004, 3:933-940.
2. Ahmad N., Gupta S., Husain M.M., Heiskanen K.M., Mukhtar H. Differential antiproliferative and apoptotic response of sanguinarine for cancer cells versus normal cells. Clinical Cancer Research 2000, 6:1524-1528.
3. Ambrosini G., Adida C., Altieri D.C. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nature Medicine 1997, 3:917-921.
4. Arancia G., Molinari A., Calcabrini A., Meschini S., Cianfriglia M. Intracellular P-glycoprotein in multidrug resistant tumor cells. Italian Journal of Anatomy and Embryology 2001, 106:59-68.
5. Bensky D., Gamble A., Kaptchuk T. Chinese herbal medicine materia medica 1992, Eastland Press, Seattle, WA.
6. Burges A., Schmalfeldt B. Ovarian cancer: diagnosis and treatment. Deutsches Ärzteblatt International 2011, 108:635-641.
7. Cassileth B.R. Complementary and alternative cancer medicine. Journal of Clinical Oncology 1999, 17:44-52.
8. Cassileth B.R., Vickers A.J. High prevalence of complementary and alternative medicine use among cancer patients: implications for research and clinical care. Journal of Clinical Oncology 2005, 23:2590-2592.
9. Chang A. Chemotherapy, chemoresistance and the changing treatment landscape for NSCLC. Lung Cancer 2011, 71:3-10.
10. Chen C.H., Liao C.H., Chang Y.L., Guh J.H., Pan S.L., Teng C.M. Protopine a novel microtubule-stabilizing agent, causes mitotic arrest and apoptotic cell death in human hormone-refractory prostate cancer cell lines. Cancer Letters 2012, 315:1-11.
11. Choi W.Y., Kim G.Y., Lee W.H., Choi Y.H. Sanguinarine a benzophenanthridine alkaloid, induces apoptosis in MDA-MB-231 human breast carcinoma cells through a reactive oxygen species-mediated mitochondrial pathway. Chemotherapy 2008, 54:279-287.
12. Clegg A., Scott D.A., Hewitson P., Sidhu M., Waugh N. Clinical and cost effectiveness of paclitaxel, docetaxel, gemcitabine, and vinorelbine in non-small cell lung cancer: a systematic review. Thorax 2002, 57:20-28.
13. Duke J.A., Ayenus E.S. Medicinal plants of China 1984, Reference Publications, Inc., Algonac.
14. Franz C, Bauer R, Carle R, Tedesco D, Tubaro A, Zitterl-Eglseer K. Assessment of plants/herbs, plant herb extracts and their naturally or synthetically produced components as "addictives" for use in animal production. CFT/EFSA/FEEDAP/2005/01; 2005, p. 140-52.
15. Gao J., Morgan W.A., Sanchez-Medina A., Corcoran O. The ethanol extract of Scutellaria baicalensis and the active compounds induce cell cycle arrest and apoptosis including upregulation of p53 and Bax in human lung cancer cells. Toxicology and Applied Pharmacology 2011, 254:221-228.
16. Goodman L.S., Wintrobe M.M., Dameshek W., Goodman M.J., Gilman A., McLennan M.T. Nitrogen mustard therapy; use of methyl-bis (beta-chloroethyl) amine hydrochloride and tris (beta-chloroethyl) amine hydrochloride for Hodgkin's disease, lymphosarcoma, leukemia and certain allied and miscellaneous disorders. JAMA 1946, 132:126-132.
17. Grieve M. A modern herbal 1984, Penguin Books, Middlesex.
18. Habermehl D., Kammerer B., Handrick R., Eldh T., Gruber C., Cordes N., et al. Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathway. BMC Cancer 2006, 6:14.
19. Hallock S., Tang S.C., Buja L.M., Trump B.F., Liepins A., Weerasinghe P. Aurintricarboxylic acid inhibits protein synthesis independent, sanguinarine-induced apoptosis and oncosis. Toxicologic Pathology 2007, 35:300-309.
20. Han M.H., Yoo Y.H., Choi Y.H. Sanguinarine-induced apoptosis in human leukemia U937 cells via Bcl-2 downregulation and caspase-3 activation. Chemotherapy 2008, 54:157-165.
21. Huang K.C. The pharmacology of Chinese herbs 1993, CRC Press, Boca Raton, FL.
22. Jemal A., Siegel R., Xu J., Ward E. Cancer statistics, 2010. CA: A Cancer Journal for Clinicians 2010, 60:277-300.
23. Jeong S.J., Koh W., Kim B., Kim S.H. Are there new therapeutic options for treating lung cancer based on herbal medicines and their metabolites?. Journal of Ethnopharmacology 2011, 138:652-661.
24. Jiangsu N.M.C. Dictionary of traditional Chinese medicines 1986, Shanghai Scientific and Technological Publishing House, Shanghai.
25. Kemeny-Beke A., Aradi J., Damjanovich J., Beck Z., Facsko A., Berta A., et al. Apoptotic response of uveal melanoma cells upon treatment with chelidonine, sanguinarine and chelerythrine. Cancer Letters 2006, 237:67-75.
26. Kosina P., Gregorova J., Gruz J., Vacek J., Kolar M., Vogel M., et al. Phytochemical and antimicrobial characterization of Macleaya cordata herb. Fitoterapia 2010, 81:1006-1012.
27. Kumar V., Abbas A.K., Fausto N., Robbins S.L., Cotran R.S. Robbins and Cotran pathologic basis of disease 2005, Elsevier Saunders, Philadelphia. 7th ed.
28. Lau F.Y., Chui C.H., Gambari R., Kok S.H., Kan K.L., Cheng G.Y., et al. Antiproliferative and apoptosis-inducing activity of Brucea javanica extract on human carcinoma cells. International Journal of Molecular Medicine 2005, 16:1157-1162.
29. Lee I.S., Nishikawa A., Furukawa F., Kasahara K., Kim S.U. Effects of Selaginella tamariscina on in vitro tumor cell growth, p53 expression, G1 arrest and in vivo gastric cell proliferation. Cancer Letters 1999, 144:93-99.
30. Lee J.S., Jung W.K., Jeong M.H., Yoon T.R., Kim H.K. Sanguinarine induces apoptosis of HT-29 human colon cancer cells via the regulation of Bax/Bcl-2 ratio and caspase-9-dependent pathway. International Journal of Toxicology 2012, 31:70-77.
31. Li W.Y., Chan S.W., Guo D.J., Chung M.K., Leung T.Y., Yu P.H. Water extract of Rheum officinale Baill, induces apoptosis in human lung adenocarcinoma A549 and human breast cancer MCF-7 cell lines. Journal of Ethnopharmacology 2009, 124:251-256.
32. Lindermayer H. Überprüfung der leistungsfördernden Wirksamkeit des phytogenen Zusatzstoffes Sangrovit bei Mastschweinen. Bayerische Landesanstalt für Landwirtschaft: Institut für Tierernährung und Futterwirtschaft; 2005.
33. Matkar S.S., Wrischnik L.A., Hellmann-Blumberg U. Production of hydrogen peroxide and redox cycling can explain how sanguinarine and chelerythrine induce rapid apoptosis. Archives of Biochemistry and Biophysics 2008, 477:43-52.
34. Matkar S.S., Wrischnik L.A., Hellmann-Blumberg U. Sanguinarine causes DNA damage and p53-independent cell death in human colon cancer cell lines. Chemico-Biological Interactions 2008, 172:63-71.
35. Newman S.E., Roll M.J., Harkrader R.J. A naturally occurring compound for controlling powdery mildew of greenhouse roses. Hortscience 1999, 34:686-689.
36. Olaussen K.A., Dunant A., Fouret P., Brambilla E., Andre F., Haddad V., et al. DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy. New England Journal of Medicine 2006, 355:983-991.
37. Olaussen K.A., Fouret P., Kroemer G. ERCC1-specific immunostaining in non-small-cell lung cancer. New England Journal of Medicine 2007, 357:1559-1561.
38. Pang J-x, Ma R-q, Liu L-m, Jiang Y.-p., Sun L.-s. Total alkaloid of Macleaya cordata: in vitro cytotoxic effect on Hep3B cells and in vivo antitumor effect in mice. Journal of First Military Medical University 2005, 25:325-328.
39. Park K.I., Park H.S., Kang S.R., Nagappan A., Lee D.H., Kim J.A., et al. Korean Scutellaria baicalensis water extract inhibits cell cycle G1/S transition by suppressing cyclin D1 expression and matrix-metalloproteinase-2 activity in human lung cancer cells. Journal of Ethnopharmacology 2011, 133:634-641.
40. Park S.C., Yoo H.S., Park C., Cho C.K., Kim G.Y., Kim W.J., et al. Induction of apoptosis in human lung carcinoma cells by the water extract of Panax notoginseng is associated with the activation of caspase-3 through downregulation of Akt. International Journal of Oncology 2009, 35:121-127.
41. Parkin D.M., Bray F., Ferlay J., Pisani P. Global cancer statistics, 2002. CA: A Cancer Journal for Clinicians 2005, 55:74-108.
42. Psotova J., Vecera R., Zdarilova A., Anzenbacherova E., Kosina P., Svobodova A., et al. Safety assessment of sanguiritrin, alkaloid fraction of Macleaya cordata, in rats. Veterinarni Medicina 2006, 51:145-155.
43. Schettino C., Bareschino M.A., Maione P., Rossi A., Ciardiello F., Gridelli C. The potential role of pharmacogenomic and genomic in the adjuvant treatment of early stage non small cell lung cancer. Current Genomics 2008, 9:252-262.
44. Sedo A., Vlasicova K., Bartak P., Vespalec R., Vicar J., Simanek V., et al. Quaternary benzo[c]phenanthridine alkaloids as inhibitors of aminopeptidase N and dipeptidyl peptidase IV. Phytotherapy Research 2002, 16:84-87.
45. Seve P., Dumontet C. Is class III beta-tubulin a predictive factor in patients receiving tubulin-binding agents. Lancet Oncology 2008, 9:168-175.
46. Shoemaker M., Hamilton B., Dairkee S.H., Cohen I., Campbell M.J. In vitro anticancer activity of twelve Chinese medicinal herbs. Phytotherapy Research 2005, 19:649-651.
47. Slichenmyer W.J., Von Hoff D.D. New natural products in cancer chemotherapy. Journal of Clinical Pharmacology 1990, 30:770-788.
48. Stiborova M., Vostalova J., Zdarilova A., Ulrichova J., Hudecek J., Tschirner K., et al. Macleaya cordata extract and Sangrovit genotoxicity. Assessment in vivo. Biomedical Papers of the Medical Faculty of the University Palacky, Olomouc, Czech Republic 2008, 152:35-39.
49. Suggitt M., Bibby M.C. 50 years of preclinical anticancer drug screening: empirical to target-driven approaches. Clinical Cancer Research 2005, 11:971-981.
50. Sun M., Lou W., Chun J.Y., Cho D.S., Nadiminty N., Evans C.P., et al. Sanguinarine suppresses prostate tumor growth and inhibits survivin expression. Genes & Cancer 2010, 1:283-292.
51. Sun S., Li X.L., Wang C.Z., Williams S., Yuan C.S. Improving anticancer activities of Oplopanax horridus root bark extract by removing water-soluble components. Phytotherapy Research 2010, 24:1166-1174.
52. Tsukamoto H., Kondo S., Mukudai Y., Nagumo T., Yasuda A., Kurihara Y., et al. Evaluation of anticancer activities of benzo[c]phenanthridine alkaloid sanguinarine in oral squamous cell carcinoma cell line. Anticancer Research 2011, 31:2841-2846.
53. Ulrichova J., Dvorak Z., Vicar J., Lata J., Smrzova J., Sedo A., et al. Cytotoxicity of natural compounds in hepatocyte cell culture models, The case of quaternary benzo[c]phenanthridine alkaloids. Toxicology Letters 2001, 125:125-132.
54. Vieira S.L., Berres J., Reis R.N., Oyarzabal O.A., Coneglian J.L.B., Freitas D.M., et al. Studies with sanguinarine like alkaloids as feed additive in broiler diets. Brazilian Journal of Poultry Science 2008, 10:67-71.
55. Walterova D., Ulrichova Preininger V., Simanek V., Lenfeld J., Lasovsky J. Inhibition of liver alanine aminotransferase activity by some benzophenanthridine alkaloids. Journal of Medicinal Chemistry 1981, 24:1100-1103.
56. Walterova D., Ulrichova J., Valka I., Vicar J., Vavreckova C., Taborska E., et al. Benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine: biological activities and dental care applications. Acta Universitatis Palackianae Olomucensis Facultatis Medicae 1995, 139:7-16.
57. Xu G.J., Wang Q., Yu B.M. Color illustrations of antitumor traditional Chinese medicine 1997, Fujian Scientific and Technological Publishing House, Fujian.
58. Yang J., Wang J., Liu X., Fang X. Experimental studies on pharmacodynamic effect of Macleaya cordata. Zhong Yao Cai 1999, 22:82-85.
59. Yang S.F., Chu S.C., Liu S.J., Chen Y.C., Chang Y.Z., Hsieh Y.S. Antimetastatic activities of Selaginella tamariscina (Beauv.) on lung cancer cells in vitro and in vivo. Journal of Ethnopharmacology 2007, 110:483-489.
60. Yang X. Encyclopedic reference of traditional Chinese medicine 2003, Springer, Berlin, Germany.
61. Ye F., Feng F., Liu W. Alkaloids from Macleaya cordata. Zhongguo Zhong Yao Za Zhi 2009, 34:1683-1686.
62. Zdarilova A., Vrublova E., Vostalova J., Klejdus B., Stejskal D., Proskova J., et al. Natural feed additive of Macleaya cordata: safety assessment in rats a 90-day feeding experiment. Food and Chemical Toxicology 2008, 46:3721-3726.
63. Zdenek D., Vlastimil K., Borivoj K., Jan H., Jaroslav V., Jitka U., et al. Quaternary benzo[c]phenanthridines sanguinarine and chelerythrine: a review of investigation from chemical and biological studies. Heterocycles 2006, 68:2403-2422.
64. Zee-Cheng R.K., Cheng C.C. Screening and evaluation of anticancer agents. Methods and Findings in Experimental and Clinical Pharmacology 1988, 10:67-101.
65. Zhang D.Y., Kong Q.Q., Zhang C.B., Zhu J.H., Chen M.D., Wang P. Expression of Bcl-2 and Bax proteins in myocardial cells after Macleaya cordata alkaloids poisoning in rats. Fa Yi Xue Za Zhi 2009, 25:246-248. 253.
66. Zubrod C.G. The national program for cancer chemotherapy. JAMA 1972, 222:1161-1162.