Natural feed additive of Macleaya cordata: Safety assessment in rats a 90-day feeding experiment

Food and Chemical Toxicology

Volumn 46, Issue 12, 2008, Pages 3721-3726

  Zdarilova, Adela ^a   Vrublova, Eva ^a   Vostalova, Jitka ^a   Klejdus, Borivoj ^b   Stejskal, David ^c   Proskova, Jitka ^c   Kosina, Pavel ^a   Svobodova, Alena ^a   Vecera, Rostislav ^a   Hrbac, Jan ^a   Cernochova, Drahomira ^a   Vicar, Jaroslav ^a   Ulrichova, Jitka ^a   Simanek, Vilim ^a  

^a PALACKÝ UNIVERSITY   (Czech Republic)

^b MENDEL UNIVERSITY IN BRNO   (Czech Republic)

^c Sternberk Hospital   (Czech Republic)

Author keywords

Chelerythrine; Feed additive; Macleaya cordata; Quaternary benzo c phenanthridine alkaloids; Rat; Safety; Sanguinarine

Indexed keywords

ALKALOID DERIVATIVE; BENZO[C]PHENANTHRIDINE DERIVATIVE; CYTOCHROME P450; FOOD ADDITIVE; GLUTATHIONE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; ENZYME ACTIVITY; FEEDING; HEART; ILEUM; KIDNEY; LIVER; MACLEAYA CORDATA; MALE; MORPHOLOGY; NONHUMAN; ORGAN WEIGHT; OXIDATIVE STRESS; PAPAVERACEAE; RAT; SAFETY; TONGUE;

ANIMAL FEED; ANIMALS; BENZOPHENANTHRIDINES; BLOOD CELL COUNT; BODY WEIGHT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; DIET; DRUGS, CHINESE HERBAL; EATING; FECES; FOOD ADDITIVES; ISOQUINOLINES; LIVER; MALE; ORGAN SIZE; OXIDATIVE STRESS; PAPAVERACEAE; PILOT PROJECTS; RATS; RATS, WISTAR; TISSUE DISTRIBUTION;

ANIMALIA; MACLEAYA CORDATA; PAPAVERACEAE; RATTUS; RATTUS NORVEGICUS;

EID: 56149091162     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2008.09.054     Document Type: Article

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