Microsomal epoxide hydrolase (EPHX1) polymorphisms are associated with aberrant promoter methylation of ERCC3 and hematotoxicity in benzene-exposed workers

Environmental and Molecular Mutagenesis

Volumn 54, Issue 6, 2013, Pages 397-405

  Xing, Caihong ^a,b,c   Chen, Qi ^d   Li, Guilan ^c   Zhang, Linyuan ^c   Zheng, Min ^c   Zou, Zhengyong ^b   Hou, Lifang ^d   Wang, Qian Fei ^b   Liu, Xin ^d   Guo, Xinbiao ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b Chinese Academy of Sciences   (China)

^c CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^d NORTHWESTERN UNIVERSITY   (United States)

Author keywords

ERCC3; Genetic polymorphism; Methylation; Microsomal epoxide hydrolase; Occupational exposure

Indexed keywords

BENZENE; CYTOCHROME P450 1A1; EPOXIDE HYDROLASE;

ARTICLE; BLOOD TOXICITY; DNA METHYLATION; EPIGENETICS; FEMALE; GENETIC ASSOCIATION; GENOTYPE; HUMAN; INDUSTRIAL WORKER; LEUKOPENIA; MAJOR CLINICAL STUDY; MALE; OCCUPATIONAL EXPOSURE; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM;

ERCC3; GENETIC POLYMORPHISM; METHYLATION; MICROSOMAL EPOXIDE HYDROLASE; OCCUPATIONAL EXPOSURE;

BENZENE; CHINA; CYTOCHROME P-450 CYP1A1; DNA HELICASES; DNA METHYLATION; DNA-BINDING PROTEINS; ENVIRONMENTAL POLLUTANTS; EPOXIDE HYDROLASES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HEMATOLOGIC DISEASES; HUMANS; MALE; MIDDLE AGED; NAD(P)H DEHYDROGENASE (QUINONE); OCCUPATIONAL EXPOSURE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC;

EID: 84880041672     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.21786     Document Type: Article

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