Galectin-3 negatively regulates the frequency and function of CD4+CD25+Foxp3+ regulatory T cells and influences the course of Leishmania major infection

European Journal of Immunology

Volumn 43, Issue 7, 2013, Pages 1806-1817

  Fermino, Marise L ^a   Dias, Fabrício C ^a   Lopes, Carla D ^a   Souza, Maria A ^a,b   Cruz, Ângela K ^a   Liu, Fu Tong ^c   Chammas, Roger ^a   Roque Barreira, Maria Cristina ^a   Rabinovich, Gabriel A ^d,e   Bernardes, Emerson S ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF UBERLÂNDIA   (Brazil)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^e UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Galectin 3; IL 10; Leishmania major; Notch signaling; T regulatory (Treg) cells

Indexed keywords

CD103 ANTIGEN; GALECTIN 3; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; NOTCH1 RECEPTOR; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR HES 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; EFFECTOR CELL; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LEISHMANIA MAJOR; LEISHMANIASIS; LYMPH NODE; LYMPHOCYTE FUNCTION; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PARASITE LOAD; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; WILD TYPE;

GALECTIN-3; IL-10; LEISHMANIA MAJOR; NOTCH SIGNALING; T REGULATORY (TREG) CELLS;

ANIMALS; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; GALECTIN 3; IMMUNOHISTOCHEMISTRY; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, NOTCH; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTES, REGULATORY;

EID: 84880015001     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201343381     Document Type: Article

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