BBS7 is required for BBSome formation and its absence in mice results in bardet-biedl syndrome phenotypes and selective abnormalities in membrane protein trafficking

Journal of Cell Science

Volumn 126, Issue 11, 2013, Pages 2372-2380

  Zhang, Qihong ^a   Nishimura, Darryl ^a   Vogel, Tim ^a   Shao, Jianqiang ^b   Swiderski, Ruth ^a   Yin, Terry ^a   Searby, Charles ^a   Carter, Calvin S ^b   Kim, GunHee ^a   Bugge, Kevin ^a   Stone, Edwin M ^a   Sheffield, Val C ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Bardet Biedl syndrome; Bbsome; Cilia; Protein trafficking

Indexed keywords

BARDET BIEDL SYNDROME PROTEIN 2; BARDET BIEDL SYNDROME PROTEIN 7; DOPAMINE 1 RECEPTOR; MEMBRANE PROTEIN; MESSENGER RNA; POLYCYSTIN 1; POLYCYSTIN 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AXONEME; BARDET BIEDL SYNDROME; BITTER TASTE; CONTROLLED STUDY; IN VIVO STUDY; MALE; MALE INFERTILITY; MOUSE; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STABILITY; PROTEIN TRANSPORT; RETINA DEGENERATION; SPERMATOZOON ABNORMALITY;

BARDET BIEDL SYNDROME; BBSOME; CILIA; PROTEIN TRAFFICKING;

ANIMALS; BARDET-BIEDL SYNDROME; CARRIER PROTEINS; CELL MEMBRANE; CILIA; DISEASE MODELS, ANIMAL; INFERTILITY, MALE; MALE; MICE; MICE, KNOCKOUT; MOLECULAR CHAPERONES; MULTIPROTEIN COMPLEXES; OBESITY; RECEPTORS, DOPAMINE D1; RETINAL DEGENERATION; TRPP CATION CHANNELS;

MUS;

EID: 84880005129     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.111740     Document Type: Article

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