Potentiation of inflammatory CXCL8 signalling sustains cell survival in pten-deficient prostate carcinoma

European Urology

Volumn 64, Issue 2, 2013, Pages 177-188

  Maxwell, Pamela J ^a   Coulter, Jonathan ^a   Walker, Steven M ^a,b   McKechnie, Melanie ^a   Neisen, Jessica ^a   McCabe, Nuala ^b   Kennedy, Richard D ^a,b   Salto Tellez, Manuel ^a   Albanese, Chris ^c   Waugh, David J J ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b Almac Sciences   (United Kingdom)

^c GEORGETOWN UNIVERSITY   (United States)

Author keywords

Apoptosis; CXCL8; CXCR2; Hypoxia; Inflammation; Prostate cancer; PTEN

Indexed keywords

CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; HYPOXIA INDUCIBLE FACTOR 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; SHORT HAIRPIN RNA; SMALL INTERFERING RNA;

ALLELE; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; B LYMPHOCYTE ACTIVATION; CANCER CELL; CELL CYCLE; CELL FUNCTION; CELL SURVIVAL; G1 PHASE CELL CYCLE CHECKPOINT; GENE CONTROL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE; PROSTATE CARCINOMA; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

APOPTOSIS; CXCL8; CXCR2; HYPOXIA; INFLAMMATION; PROSTATE CANCER; PTEN;

ANIMALS; APOPTOSIS; AUTOCRINE COMMUNICATION; CARCINOMA; CELL HYPOXIA; CELL LINE, TUMOR; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-8; MALE; MICE; MICE, KNOCKOUT; PROSTATIC NEOPLASMS; PTEN PHOSPHOHYDROLASE; RECEPTORS, INTERLEUKIN-8A; RECEPTORS, INTERLEUKIN-8B; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSFECTION; UP-REGULATION;

EID: 84879974599     PISSN: 03022838     EISSN: 18737560     Source Type: Journal    
DOI: 10.1016/j.eururo.2012.08.032     Document Type: Article

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