메뉴 건너뛰기




Volumn 8, Issue 7, 2013, Pages

A Novel 3D Label-Free Monitoring System of hES-Derived Cardiomyocyte Clusters: A Step Forward to In Vitro Cardiotoxicity Testing

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; DOXORUBICIN; NORADRENALIN;

EID: 84879968282     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0068971     Document Type: Article
Times cited : (31)

References (38)
  • 1
    • 79954999150 scopus 로고    scopus 로고
    • Cardiotoxicity testing using pluripotent stem cell-derived human cardiomyocytes and state-of-the-art bioanalytics: a review
    • Mandenius CF, Steel D, Noor F, Meyer T, Heinzle E, et al. (2011) Cardiotoxicity testing using pluripotent stem cell-derived human cardiomyocytes and state-of-the-art bioanalytics: a review. J Appl Toxicol 31: 191-205.
    • (2011) J Appl Toxicol , vol.31 , pp. 191-205
    • Mandenius, C.F.1    Steel, D.2    Noor, F.3    Meyer, T.4    Heinzle, E.5
  • 2
    • 84859641526 scopus 로고    scopus 로고
    • Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG
    • Jonsson MK, Vos MA, Mirams GR, Duker G, Sartipy P,et al. (2012) Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG. J Mol Cell Cardiol.
    • (2012) J Mol Cell Cardiol
    • Jonsson, M.K.1    Vos, M.A.2    Mirams, G.R.3    Duker, G.4    Sartipy, P.5
  • 3
    • 84879958431 scopus 로고    scopus 로고
    • Cardiotoxicity of cancer therapeutics: current issues in screening, prevention, and therapy
    • Sheppard RJ, Berger J, Sebag IA, (2013) Cardiotoxicity of cancer therapeutics: current issues in screening, prevention, and therapy. Front Pharmacol 4: 19.
    • (2013) Front Pharmacol , vol.4 , pp. 19
    • Sheppard, R.J.1    Berger, J.2    Sebag, I.A.3
  • 4
    • 0035145286 scopus 로고    scopus 로고
    • Species plays an important role in drug-induced prolongation of action potential duration and early afterdepolarizations in isolated Purkinje fibers
    • Lu HR, Marien R, Saels A, De Clerck F, (2001) Species plays an important role in drug-induced prolongation of action potential duration and early afterdepolarizations in isolated Purkinje fibers. J Cardiovasc Electrophysiol 12: 93-102.
    • (2001) J Cardiovasc Electrophysiol , vol.12 , pp. 93-102
    • Lu, H.R.1    Marien, R.2    Saels, A.3    De Clerck, F.4
  • 5
    • 79951496281 scopus 로고    scopus 로고
    • Cardiomyocyte clusters derived from human embryonic stem cells share similarities with human heart tissue
    • Asp J, Steel D, Jonsson M, Ameen C, Dahlenborg K, et al. (2010) Cardiomyocyte clusters derived from human embryonic stem cells share similarities with human heart tissue. J Mol Cell Biol 2: 276-283.
    • (2010) J Mol Cell Biol , vol.2 , pp. 276-283
    • Asp, J.1    Steel, D.2    Jonsson, M.3    Ameen, C.4    Dahlenborg, K.5
  • 6
    • 84872245899 scopus 로고    scopus 로고
    • Effective cardiac myocyte differentiation of human induced pluripotent stem cells requires VEGF
    • Ye L, Zhang S, Greder L, Dutton J, Keirstead SA, et al. (2013) Effective cardiac myocyte differentiation of human induced pluripotent stem cells requires VEGF. PLoS One 8: e53764.
    • (2013) PLoS One , vol.8
    • Ye, L.1    Zhang, S.2    Greder, L.3    Dutton, J.4    Keirstead, S.A.5
  • 7
    • 79954543387 scopus 로고    scopus 로고
    • A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability
    • Burridge PW, Thompson S, Millrod MA, Weinberg S, Yuan X, et al. (2011) A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability. PLoS One 6: e18293.
    • (2011) PLoS One , vol.6
    • Burridge, P.W.1    Thompson, S.2    Millrod, M.A.3    Weinberg, S.4    Yuan, X.5
  • 8
    • 52949109296 scopus 로고    scopus 로고
    • Molecular signature of cardiomyocyte clusters derived from human embryonic stem cells
    • Synnergren J, Akesson K, Dahlenborg K, Vidarsson H, Ameen C, et al. (2008) Molecular signature of cardiomyocyte clusters derived from human embryonic stem cells. Stem Cells 26: 1831-1840.
    • (2008) Stem Cells , vol.26 , pp. 1831-1840
    • Synnergren, J.1    Akesson, K.2    Dahlenborg, K.3    Vidarsson, H.4    Ameen, C.5
  • 9
    • 84857762746 scopus 로고    scopus 로고
    • Global transcriptional profiling reveals similarities and differences between human stem cell-derived cardiomyocyte clusters and heart tissue
    • Synnergren J, Ameen C, Jansson A, Sartipy P, (2012) Global transcriptional profiling reveals similarities and differences between human stem cell-derived cardiomyocyte clusters and heart tissue. Physiol Genomics 44: 245-258.
    • (2012) Physiol Genomics , vol.44 , pp. 245-258
    • Synnergren, J.1    Ameen, C.2    Jansson, A.3    Sartipy, P.4
  • 10
    • 58449092608 scopus 로고    scopus 로고
    • Cardiomyocytes derived from human embryonic stem cells - characteristics and utility for drug discovery
    • Steel D, Hyllner J, Sartipy P, (2009) Cardiomyocytes derived from human embryonic stem cells- characteristics and utility for drug discovery. Curr Opin Drug Discov Devel 12: 133-140.
    • (2009) Curr Opin Drug Discov Devel , vol.12 , pp. 133-140
    • Steel, D.1    Hyllner, J.2    Sartipy, P.3
  • 11
    • 65549134641 scopus 로고    scopus 로고
    • Local control of excitation-contraction coupling in human embryonic stem cell-derived cardiomyocytes
    • Zhu WZ, Santana LF, Laflamme MA, (2009) Local control of excitation-contraction coupling in human embryonic stem cell-derived cardiomyocytes. PLoS One 4: e5407.
    • (2009) PLoS One , vol.4
    • Zhu, W.Z.1    Santana, L.F.2    Laflamme, M.A.3
  • 12
    • 77949293236 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells to cardiomyocytes for in vitro and in vivo applications
    • Vidarsson H, Hyllner J, Sartipy P, (2010) Differentiation of human embryonic stem cells to cardiomyocytes for in vitro and in vivo applications. Stem Cell Rev 6: 108-120.
    • (2010) Stem Cell Rev , vol.6 , pp. 108-120
    • Vidarsson, H.1    Hyllner, J.2    Sartipy, P.3
  • 13
    • 83755172797 scopus 로고    scopus 로고
    • Comparison of the IKr blockers moxifloxacin, dofetilide and E-4031 in five screening models of pro-arrhythmia reveals lack of specificity of isolated cardiomyocytes
    • Nalos L, Varkevisser R, Jonsson MK, Houtman MJ, Beekman JD, et al. (2012) Comparison of the IKr blockers moxifloxacin, dofetilide and E-4031 in five screening models of pro-arrhythmia reveals lack of specificity of isolated cardiomyocytes. Br J Pharmacol 165: 467-478.
    • (2012) Br J Pharmacol , vol.165 , pp. 467-478
    • Nalos, L.1    Varkevisser, R.2    Jonsson, M.K.3    Houtman, M.J.4    Beekman, J.D.5
  • 14
    • 77952253259 scopus 로고    scopus 로고
    • Progressive maturation in contracting cardiomyocytes derived from human embryonic stem cells: Qualitative effects on electrophysiological responses to drugs
    • Otsuji TG, Minami I, Kurose Y, Yamauchi K, Tada M, et al. (2010) Progressive maturation in contracting cardiomyocytes derived from human embryonic stem cells: Qualitative effects on electrophysiological responses to drugs. Stem Cell Res 4: 201-213.
    • (2010) Stem Cell Res , vol.4 , pp. 201-213
    • Otsuji, T.G.1    Minami, I.2    Kurose, Y.3    Yamauchi, K.4    Tada, M.5
  • 15
    • 23944486374 scopus 로고    scopus 로고
    • Cells on a chip-the use of electric properties for highly sensitive monitoring of blood-derived factors involved in angiotensin II type 1 receptor signalling
    • Rothermel A, Kurz R, Ruffer M, Weigel W, Jahnke HG, et al. (2005) Cells on a chip-the use of electric properties for highly sensitive monitoring of blood-derived factors involved in angiotensin II type 1 receptor signalling. Cell Physiol Biochem 16: 51-58.
    • (2005) Cell Physiol Biochem , vol.16 , pp. 51-58
    • Rothermel, A.1    Kurz, R.2    Ruffer, M.3    Weigel, W.4    Jahnke, H.G.5
  • 16
    • 76749151845 scopus 로고    scopus 로고
    • Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes
    • Braam SR, Tertoolen L, van de Stolpe A, Meyer T, Passier R, et al. (2010) Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes. Stem Cell Res 4: 107-116.
    • (2010) Stem Cell Res , vol.4 , pp. 107-116
    • Braam, S.R.1    Tertoolen, L.2    van de Stolpe, A.3    Meyer, T.4    Passier, R.5
  • 17
    • 34247877635 scopus 로고    scopus 로고
    • Effect of cardioactive drugs on action potential generation and propagation in embryonic stem cell-derived cardiomyocytes
    • Reppel M, Igelmund P, Egert U, Juchelka F, Hescheler J, et al. (2007) Effect of cardioactive drugs on action potential generation and propagation in embryonic stem cell-derived cardiomyocytes. Cell Physiol Biochem 19: 213-224.
    • (2007) Cell Physiol Biochem , vol.19 , pp. 213-224
    • Reppel, M.1    Igelmund, P.2    Egert, U.3    Juchelka, F.4    Hescheler, J.5
  • 18
    • 41549135210 scopus 로고    scopus 로고
    • Microcavity array (MCA)-based biosensor chip for functional drug screening of 3D tissue models
    • Kloss D, Kurz R, Jahnke HG, Fischer M, Rothermel A, et al. (2008) Microcavity array (MCA)-based biosensor chip for functional drug screening of 3D tissue models. Biosens Bioelectron 23: 1473-1480.
    • (2008) Biosens Bioelectron , vol.23 , pp. 1473-1480
    • Kloss, D.1    Kurz, R.2    Jahnke, H.G.3    Fischer, M.4    Rothermel, A.5
  • 19
    • 64449085887 scopus 로고    scopus 로고
    • A microelectrode-based sensor for label-free in vitro detection of ischemic effects on cardiomyocytes
    • Krinke D, Jahnke HG, Panke O, Robitzki AA, (2009) A microelectrode-based sensor for label-free in vitro detection of ischemic effects on cardiomyocytes. Biosens Bioelectron 24: 2798-2803.
    • (2009) Biosens Bioelectron , vol.24 , pp. 2798-2803
    • Krinke, D.1    Jahnke, H.G.2    Panke, O.3    Robitzki, A.A.4
  • 20
    • 77957888595 scopus 로고    scopus 로고
    • Real-time monitoring of relaxation and contractility of smooth muscle cells on a novel biohybrid chip
    • Haas S, Jahnke HG, Glass M, Azendorf R, Schmidt S, et al. (2010) Real-time monitoring of relaxation and contractility of smooth muscle cells on a novel biohybrid chip. Lab Chip 10: 2965-2971.
    • (2010) Lab Chip , vol.10 , pp. 2965-2971
    • Haas, S.1    Jahnke, H.G.2    Glass, M.3    Azendorf, R.4    Schmidt, S.5
  • 21
    • 79960454962 scopus 로고    scopus 로고
    • A novel organotypic tauopathy model on a new microcavity chip for bioelectronic label-free and real time monitoring
    • Krinke D, Jahnke HG, Mack TG, Hirche A, Striggow F, et al. (2010) A novel organotypic tauopathy model on a new microcavity chip for bioelectronic label-free and real time monitoring. Biosens Bioelectron 26: 162-168.
    • (2010) Biosens Bioelectron , vol.26 , pp. 162-168
    • Krinke, D.1    Jahnke, H.G.2    Mack, T.G.3    Hirche, A.4    Striggow, F.5
  • 22
    • 84855772725 scopus 로고    scopus 로고
    • Impedance spectroscopy based measurement system for quantitative and label-free real-time monitoring of tauopathy in hippocampal slice cultures
    • Jahnke HG, Braesigk A, Mack TG, Ponick S, Striggow F, et al. (2012) Impedance spectroscopy based measurement system for quantitative and label-free real-time monitoring of tauopathy in hippocampal slice cultures. Biosens Bioelectron 32: 250-258.
    • (2012) Biosens Bioelectron , vol.32 , pp. 250-258
    • Jahnke, H.G.1    Braesigk, A.2    Mack, T.G.3    Ponick, S.4    Striggow, F.5
  • 23
    • 33645065611 scopus 로고    scopus 로고
    • QT PRODACT: comparison of non-clinical studies for drug-induced delay in ventricular repolarization and their role in safety evaluation in humans
    • Omata T, Kasai C, Hashimoto M, Hombo T, Yamamoto K, (2005) QT PRODACT: comparison of non-clinical studies for drug-induced delay in ventricular repolarization and their role in safety evaluation in humans. J Pharmacol Sci 99: 531-541.
    • (2005) J Pharmacol Sci , vol.99 , pp. 531-541
    • Omata, T.1    Kasai, C.2    Hashimoto, M.3    Hombo, T.4    Yamamoto, K.5
  • 24
  • 25
    • 65649128544 scopus 로고    scopus 로고
    • An impedimetric microelectrode-based array sensor for label-free detection of tau hyperphosphorylation in human cells
    • Jahnke HG, Rothermel A, Sternberger I, Mack TG, Kurz RG, et al. (2009) An impedimetric microelectrode-based array sensor for label-free detection of tau hyperphosphorylation in human cells. Lab Chip 9: 1422-1428.
    • (2009) Lab Chip , vol.9 , pp. 1422-1428
    • Jahnke, H.G.1    Rothermel, A.2    Sternberger, I.3    Mack, T.G.4    Kurz, R.G.5
  • 26
    • 67049088173 scopus 로고    scopus 로고
    • A translational approach to detecting drug-induced cardiac injury with cardiac troponins: consensus and recommendations from the Cardiac Troponins Biomarker Working Group of the Health and Environmental Sciences Institute
    • Berridge BR, Pettit S, Walker DB, Jaffe AS, Schultze AE, et al. (2009) A translational approach to detecting drug-induced cardiac injury with cardiac troponins: consensus and recommendations from the Cardiac Troponins Biomarker Working Group of the Health and Environmental Sciences Institute. Am Heart J 158: 21-29.
    • (2009) Am Heart J , vol.158 , pp. 21-29
    • Berridge, B.R.1    Pettit, S.2    Walker, D.B.3    Jaffe, A.S.4    Schultze, A.E.5
  • 27
    • 84862285036 scopus 로고    scopus 로고
    • Simultaneous voltage and calcium mapping of genetically purified human induced pluripotent stem cell-derived cardiac myocyte monolayers
    • Lee P, Klos M, Bollensdorff C, Hou L, Ewart P, et al. (2012) Simultaneous voltage and calcium mapping of genetically purified human induced pluripotent stem cell-derived cardiac myocyte monolayers. Circ Res 110: 1556-1563.
    • (2012) Circ Res , vol.110 , pp. 1556-1563
    • Lee, P.1    Klos, M.2    Bollensdorff, C.3    Hou, L.4    Ewart, P.5
  • 28
    • 84876755488 scopus 로고    scopus 로고
    • Ultrastructural maturation of human-induced pluripotent stem cell-derived cardiomyocytes in a long-term culture
    • Kamakura T, Makiyama T, Sasaki K, Yoshida Y, Wuriyanghai Y, et al. (2013) Ultrastructural maturation of human-induced pluripotent stem cell-derived cardiomyocytes in a long-term culture. Circ J 77: 1307-1314.
    • (2013) Circ J , vol.77 , pp. 1307-1314
    • Kamakura, T.1    Makiyama, T.2    Sasaki, K.3    Yoshida, Y.4    Wuriyanghai, Y.5
  • 29
    • 84867746044 scopus 로고    scopus 로고
    • Extracellular matrix promotes highly efficient cardiac differentiation of human pluripotent stem cells: the matrix sandwich method
    • Zhang J, Klos M, Wilson GF, Herman AM, Lian X, et al. (2012) Extracellular matrix promotes highly efficient cardiac differentiation of human pluripotent stem cells: the matrix sandwich method. Circ Res 111: 1125-1136.
    • (2012) Circ Res , vol.111 , pp. 1125-1136
    • Zhang, J.1    Klos, M.2    Wilson, G.F.3    Herman, A.M.4    Lian, X.5
  • 30
    • 0242353365 scopus 로고    scopus 로고
    • Estimation of action potential changes from field potential recordings in multicellular mouse cardiac myocyte cultures
    • Halbach M, Egert U, Hescheler J, Banach K, (2003) Estimation of action potential changes from field potential recordings in multicellular mouse cardiac myocyte cultures. Cell Physiol Biochem 13: 271-284.
    • (2003) Cell Physiol Biochem , vol.13 , pp. 271-284
    • Halbach, M.1    Egert, U.2    Hescheler, J.3    Banach, K.4
  • 31
    • 45349084219 scopus 로고    scopus 로고
    • Reproducible, ultra high-throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregates
    • Ungrin MD, Joshi C, Nica A, Bauwens C, Zandstra PW, (2008) Reproducible, ultra high-throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregates. PLoS One 3: e1565.
    • (2008) PLoS One , vol.3
    • Ungrin, M.D.1    Joshi, C.2    Nica, A.3    Bauwens, C.4    Zandstra, P.W.5
  • 32
    • 79955583972 scopus 로고    scopus 로고
    • Derivation of human induced pluripotent stem cells for cardiovascular disease modeling
    • Narsinh K, Narsinh KH, Wu JC, (2011) Derivation of human induced pluripotent stem cells for cardiovascular disease modeling. Circ Res 108: 1146-1156.
    • (2011) Circ Res , vol.108 , pp. 1146-1156
    • Narsinh, K.1    Narsinh, K.H.2    Wu, J.C.3
  • 33
    • 0028815401 scopus 로고
    • Evidence for reduction of norepinephrine uptake sites in the failing human heart
    • Bohm M, La Rosee K, Schwinger RH, Erdmann E, (1995) Evidence for reduction of norepinephrine uptake sites in the failing human heart. J Am Coll Cardiol 25: 146-153.
    • (1995) J Am Coll Cardiol , vol.25 , pp. 146-153
    • Bohm, M.1    La Rosee, K.2    Schwinger, R.H.3    Erdmann, E.4
  • 34
    • 0344492207 scopus 로고    scopus 로고
    • Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development
    • Redfern WS, Carlsson L, Davis AS, Lynch WG, MacKenzie I, et al. (2003) Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development. Cardiovasc Res 58: 32-45.
    • (2003) Cardiovasc Res , vol.58 , pp. 32-45
    • Redfern, W.S.1    Carlsson, L.2    Davis, A.S.3    Lynch, W.G.4    MacKenzie, I.5
  • 35
    • 71449093788 scopus 로고    scopus 로고
    • Introducing a new entity: chemotherapy-induced arrhythmia
    • Guglin M, Aljayeh M, Saiyad S, Ali R, Curtis AB, (2009) Introducing a new entity: chemotherapy-induced arrhythmia. Europace 11: 1579-1586.
    • (2009) Europace , vol.11 , pp. 1579-1586
    • Guglin, M.1    Aljayeh, M.2    Saiyad, S.3    Ali, R.4    Curtis, A.B.5
  • 36
    • 84875237101 scopus 로고    scopus 로고
    • Phenotypic Profiling of Structural Cardiotoxins In Vitro Reveals Dependency on Multiple Mechanisms of Toxicity
    • Pointon A, Abi-Gerges N, Cross MJ, Sidaway JE (2013) Phenotypic Profiling of Structural Cardiotoxins In Vitro Reveals Dependency on Multiple Mechanisms of Toxicity. Toxicol Sci.
    • (2013) Toxicol Sci
    • Pointon, A.1    Abi-Gerges, N.2    Cross, M.J.3    Sidaway, J.E.4
  • 37
    • 77957373096 scopus 로고    scopus 로고
    • Assaying cardiac biomarkers for toxicity testing using biosensing and cardiomyocytes derived from human embryonic stem cells
    • Andersson H, Steel D, Asp J, Dahlenborg K, Jonsson M, et al. (2010) Assaying cardiac biomarkers for toxicity testing using biosensing and cardiomyocytes derived from human embryonic stem cells. J Biotechnol 150: 175-181.
    • (2010) J Biotechnol , vol.150 , pp. 175-181
    • Andersson, H.1    Steel, D.2    Asp, J.3    Dahlenborg, K.4    Jonsson, M.5
  • 38
    • 79961113909 scopus 로고    scopus 로고
    • Kinetic targeting of pegylated liposomal doxorubicin: a new approach to reduce toxicity during chemotherapy (CARL-trial)
    • Eckes J, Schmah O, Siebers JW, Groh U, Zschiedrich S, et al. (2011) Kinetic targeting of pegylated liposomal doxorubicin: a new approach to reduce toxicity during chemotherapy (CARL-trial). BMC Cancer 11: 337.
    • (2011) BMC Cancer , vol.11 , pp. 337
    • Eckes, J.1    Schmah, O.2    Siebers, J.W.3    Groh, U.4    Zschiedrich, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.