Short-course prophylactic zinc supplementation for diarrhea morbidity in infants of 6 to 11 months

Pediatrics

Volumn 132, Issue 1, 2013, Pages

  Malik, Akash ^a   Taneja, Davendra K ^a   Devasenapathy, Niveditha ^b   Rajeshwari, K ^c  

^a All India of Medical Sciences   (India)

^b PUBLIC HEALTH FOUNDATION OF INDIA   (India)

^c MAULANA AZAD MEDICAL COLLEGE   (India)

Author keywords

Diarrhea; Infants; Randomized control trial; Zinc

Indexed keywords

PLACEBO; ZINC;

ACUTE DIARRHEA; ARTICLE; AUTOPSY; BODY WEIGHT; CONSTIPATION; CONTROLLED STUDY; DEHYDRATION; DIARRHEA; DIET SUPPLEMENTATION; DISEASE DURATION; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG FATALITY; DYSENTERY; FEMALE; HUMAN; HUMAN TISSUE; INCIDENCE; INFANT; INTENTION TO TREAT ANALYSIS; INTERVENTION STUDY; MAJOR CLINICAL STUDY; MALE; MORBIDITY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SHORT COURSE THERAPY; SOCIAL STATUS; STUNTING SYNDROME; VOMITING; WASTING SYNDROME;

DIARRHEA; INFANTS; RANDOMIZED CONTROL TRIAL; ZINC;

ADMINISTRATION, ORAL; CROSS-SECTIONAL STUDIES; DEVELOPING COUNTRIES; DIARRHEA, INFANTILE; DOUBLE-BLIND METHOD; EMIGRANTS AND IMMIGRANTS; FEMALE; FOLLOW-UP STUDIES; HUMANS; INDIA; INFANT; MALE; PATIENT SELECTION; RECURRENCE; URBAN POPULATION; ZINC SULFATE;

EID: 84879953947     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2012-2980     Document Type: Article

References (28)

1. Beisel WR. Single nutrients and immunity. Am J Clin Nutr. 1982;35(suppl 2):417-468
2. Black RE. Zinc deficiency, immune function, and morbidity and mortality from infectious disease among children in developing countries. Food Nutr Bull. 2001;22: 155-162
3. Baqui AH, Black RE, El Arifeen S, et al. Effect of zinc supplementation started during diarrhea on morbidity and mortality in Bangladeshi children: Community randomized trial. BMJ. 2002;325(7372):1059
4. Walker CL, Black RE. Zinc for the treatment of diarrhoea: Effect on diarrhoea morbidity, mortality and incidence of future episodes. Int J Epidemiol. 2010;39(suppl 1): I63-i69
5. Sazawal S, Black RE, Bhan MK. Effect of zinc supplementation during acute diarrhea on duration and severity of the episode-a community based double-blind controlled trial. N Engl J Med. 1995;333:839-844
6. Sazawal S, Black RE, Bhan MK, et al. Zinc supplementation reduces the incidence of persistent diarrhea and dysentery among low socioeconomic children in India. J Nutr. 1996;126(2):443-450
7. Sazawal S, Black RE, Bhan MK, Jalla S, Sinha A, Bhandari N. Efficacy of zinc supplementation in reducing the incidence and prevalence of acute diarrhea-a communitybased, double-blind, controlled trial. Am J Clin Nutr. 1997;66(2):413-418
8. Brown KH, Peerson JM, Baker SK, Hess SY. Preventive zinc supplementation among infants, preschoolers, and older prepubertal children. Food Nutr Bull. 2009;30(suppl 1): S12-S40
9. Bhutta ZA, Black RE, Brown KH, et al. Prevention of diarrhea and pneumonia by zinc supplementation in children in developing countries: Pooled analysis of randomized controlled trials. Zinc Investigators' Collaborative Group. J Pediatr. 1999;135(6): 689-697
10. Brown KH, Rivera JA, Bhutta Z, et al International Zinc Nutrition Consultative Group (IZiNCG). Assessment of the risk of zinc deficiency in populations. Food Nutr Bull. 2004;25(1 suppl 2):S99-S203
11. Kosek M, Bern C, Guerrant RL. The global burden of diarrhoeal disease, as estimated from studies published between 1992 and 2000. Bull World Health Organ. 2003;81: 197-204
12. World Health Organization. Diarrhoeal disease. Available at: Www.who.int/mediacentre/factsheets/fs330/en/index.html. Accessed October 7, 2010
13. Kuppuswamy B. Manual of Socioeconomic Status (Urban). Delhi, India: Manasayan; 1981
14. World Health Organization. Child growth standards. Weight-for-age. Available at: Www.who.int/childgrowth/standards/weight-for-age/en/index.html. Accessed July 23, 2011
15. World Health Organization. Child growth standards. Length/height-for-age. Available at: Www.who.int/childgrowth/standards/height-for-age/en/index.html. Accessed July 23, 2011
16. Wapnir RA. Zinc deficiency, malnutrition and the gastrointestinal tract. J Nutr. 2000; 130(suppl 5S):1388S-1392S
17. de Benoist B, Darnton-Hill I, Davidsson L, Fontaine O, Hotz C. Conclusions of the joint WHO/UNICEF/IAEA/IZiNCG interagency meeting on zinc status indicators. Food Nutr Bull. 2007;28(suppl 3):S480-S484
18. Rahman MM, Vermund SH, Wahed MA, Fuchs GJ, Baqui AH, Alvarez JO. Simultaneous zinc and vitamin A supplementation in Bangladeshi children: Randomised double blind controlled trial. BMJ. 2001;323 (7308):314-318
19. Ruel MT, Rivera JA, Santizo MC, Lönnerdal B, Brown KH. Impact of zinc supplementation on morbidity from diarrhea and respiratory infections among rural Guatemalan children. Pediatrics. 1997;99(6):808-813
20. Sur D, Gupta DN, Mondal SK, et al. Impact of zinc supplementation on diarrheal morbidity and growth pattern of low birth weight infants in Kolkata, India: A randomized, double-blind, placebo-controlled, community-based study. Pediatrics. 2003; 112(6 pt 1):1327-1332
21. Brooks WA, Santosham M, Naheed A, et al. Effect of weekly zinc supplements on incidence of pneumonia and diarrhoea in children younger than 2 years in an urban, low-income population in Bangladesh: Randomised controlled trial. Lancet. 2005; 366(9490):999-1004
22. Long KZ, Montoya Y, Hertzmark E, Santos JI, Rosado JL. A double-blind, randomized, clinical trial of the effect of vitamin A and zinc supplementation on diarrheal disease and respiratory tract infections in children in Mexico City, Mexico. Am J Clin Nutr. 2006; 83(3):693-700
23. Gupta DN, Mondal SK, Ghosh S, Rajendran K, Sur D, Manna B. Impact of zinc supplementation on diarrhoeal morbidity in rural children of West Bengal, India. Acta Paediatr. 2003;92(5):531-536
24. Penny ME, Marin RM, Duran A, et al. Randomized controlled trial of the effect of daily supplementation with zinc or multiple micronutrients on the morbidity, growth, and micronutrient status of young Peruvian children. Am J Clin Nutr. 2004;79(3):457-465
25. Bhandari N, Bahl R, Taneja S, et al. Substantial reduction in severe diarrheal morbidity by daily zinc supplementation in young north Indian children. Pediatrics. 2002;109(6). Available at: Www.pediatrics.org/cgi/content/ full/109/6/e86
26. Rosado JL, López P, Muñoz E, Martinez H, Allen LH. Zinc supplementation reduced morbidity, but neither zinc nor iron supplementation affected growth or body composition of Mexican preschoolers. Am J Clin Nutr. 1997;65:13-19
27. Aggarwal R, Sentz J, Miller MA. Role of zinc administration in prevention of childhood diarrhea and respiratory illnesses: A metaanalysis. Pediatrics. 2007;119(6):1120-1130
28. Larson CP, Nasrin D, Saha A, Chowdhury MI, Qadri F. The added benefit of zinc supplementation after zinc treatment of acute childhood diarrhoea: A randomized, doubleblind field trial. Trop Med Int Health. 2010;15 (6):754-761