Role of macrophage in tumor microenvironment: Prospect in cancer immunotherapy

European Journal of Inflammation

Volumn 11, Issue 1, 2013, Pages 1-14

  Gautam, P K ^a   Deepak, P ^a   Kumar, S ^a   Acharya, A ^a  

^a BANARAS HINDU UNIVERSITY   (India)

Author keywords

Cancer immunotherapy; Macrophage; Tumor associated macrophage

Indexed keywords

BETA INTERFERON; HEAT SHOCK PROTEIN; IMMUNOMODULATING AGENT; REACTIVE OXYGEN METABOLITE; TUMOR ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ADOPTIVE IMMUNOTHERAPY; ANGIOGENESIS; APOPTOSIS; CANCER GENE THERAPY; CANCER IMMUNOTHERAPY; CYTOTOXICITY; HUMAN; LIPOSOMAL DELIVERY; MACROPHAGE ACTIVATION; MACROPHAGE FUNCTION; METASTASIS; NONHUMAN; PHENOTYPE; REVIEW; TUMOR ASSOCIATED LEUKOCYTE; TUMOR CELL; TUMOR GROWTH; TUMOR INVASION; TUMOR MICROENVIRONMENT;

EID: 84879919590     PISSN: 1721727X     EISSN: None     Source Type: Journal    
DOI: 10.1177/1721727X1301100101     Document Type: Review

References (43)

1. Ross JA, Auger MJ. The biology of the macrophage. In: The macrophage. Burke B, Lewis CE, 2nd ed, editors. Oxford (United Kingdom), Oxford University Press; 2002.
2. Noel W, Raes G, Hassanzadeh GG, Baetselier PD, Beschin A. Alternatively activated macrophages during parasite infections. Trends Parasitol 2004; 20:126-33. (Pubitemid 38264445)
3. Volodko N, Reiner A, Rudas M, Jakesz R. Tumour-associated macrophages in breast cancer and their prognostic correlations. The Breast 1998; 7:99-105. (Pubitemid 28230834)
4. Sarireh B, Eremin O. Tumour-associated macrophages (TAMS): disordered function,immune suppression and progressive tumour growth. JR Coll Surg Edinb 2000; 45(1):1-16. (Pubitemid 35385843)
5. Siveen KS, Kuttan G, Role of macrophage in tumor progression. Immunol Lat 2009; 123:97-102.
6. MacMicking J, Xie QW, Nathan C. Nitric oxide and macrophage function. Annu Rev Immuno 1997; 15:323-50. (Pubitemid 27169284)
7. Kamo I, Friedman H. Immunosuppression and the role of suppressive factors in cancer. Adv Cancer Res1977; 25:271-321.
8. Aggarwal BB, Shishodia S, Sandur SK, Pandey MK, Sethi G. Inflammation and cancer: how hot is the link. Biochem Pharmacol 2006; 72(11):1605-21. (Pubitemid 44666739)
9. Vollmers HP, Brandlein S. Tumors: Too sweet to remember. Mol Cancer 2007; 6:78-3.
10. Janicke R, Mannel DN. Distinct tumor cell membrane constituents activate human monocytes for tumor necrosis factor synthesis. J Immunol 1990; 144:1144-50. (Pubitemid 20065065)
11. Evans R, Kamdar SJ, Duffy TM. Tumor-derived products induce IL-1α, IL-1β, TNF-α, and IL-6 gene expression in murine macrophages: distinctions between tumor-and bacterial endotoxininduced gene expression. J Leukoc Biol 1991; 49:474-82.
12. Benimetskaya L, Loike JD, Khaled Z, Loike G, Silverstein SC, Cao L, el Khoury J, Cai TQ, Stein CA. Mac-1 (CD11b/CD18) is an oligodeoxynucleotide- binding protein. Nature Medicine 1997; 3:414-20. (Pubitemid 27145683)
13. Tomas A, Luis de la CM, Fernando HC, Jose Luis VR, David VB, de Villena MCM. Tumor Microenvironment and Immune Effects of Antineoplastic Therapy in Lymphoproliferative Syndromes. J Bio Biotech 2010; 2010:1-17.
14. Vassalli, P. The pathophysiology of tumor necrosis factors. Annu Rev Immunol 1992; 10:411-52.
15. Lin W, Karin M. A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest 2007; 117(5): 1175-83. (Pubitemid 46718402)
16. Wang FQ, So J, Reierstad S, Fishman DA. Matrilysin (MMP-7) promotes invasion of ovarian cancer cells by activation of progelatinase. Int J Cancer 2005; 114:19-31. (Pubitemid 40194305)
17. Chouaib S, Asselin-Paturel C Mami-Chouaib F, Caignard A, Blay JY. The host-tumor immune conflict: from immunosuppression toresistance and destruction. Immunol Today 1997; 18:493-97. (Pubitemid 27441593)
18. Gemsa D, Kramer W, Napierski I, et al. Potentiation of macrophage tumor cytostasis by tumor-induced ascites. J Immunol 1981; 126:2143-50. (Pubitemid 11072828)
19. Moncada S, Palmer RM. J, Hibbs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991; 43:109-42.
20. Nathan CF. Secretory Products of Macrophages. J Clin Invest 1987; 79: 319-26. (Pubitemid 17009661)
21. Hoffman RA, Langrehr JM, Billiar, TR, Curran RD, Simmons RL. Alloantigen-induced activation of rat splenocytes is regulated by the oxidative metabolism of L-arginine. J Immunol 1990; 145:2220-26. (Pubitemid 20343388)
22. Murdoch C, Giannoudis A, Lewis CE. Mechanisms regulating the recruitment of macrophages into hypoxic areas of rumors and other ischemic tissues. Blood 2004; 104:2224-34. (Pubitemid 39331817)
23. Nanbu K, Konishi I, Mandai M, Kuroda H, Hamid AA, Komatsu T, Mori T. Prognostic significance of heat shock proteins Hsp70 and Hsp90 in endometrial carcinomas. Cancer Detection & Prevention 1998; 22:549-55. (Pubitemid 28537438)
24. Vargasroig LM. Heat Shock proteins and cell proliferation in human breast cancer biopsy samples. Cancer Detection & Prevention. 1997; 21:441-51.
25. Basu S, Binder RJ, Srivastava PK. Necrotic but not apoptotic cell death release heat shock protein, which deliver a partial maturation siginal to pathway. Int Immunol 2006; 55:958-68.
26. Andreesen R, Gadd S, Brugger W, Lohr GW, Atkins RC. Activation of human monocyte-derived macrophages cultured on Teflon: response to interferon-γ during terminal maturation in vitro. Immunobiology 1988; 177:186-98
27. Joseph GA, Christopher RP. Liposomal vaccines - targeting the delivery of antigen. Methods. 2006; 40:39-52
28. Schwendener RA, Ludewig B, Cerny A, Engler O. Liposome-based vaccines. Methods Mol Biol 2010; 605:163-75.
29. Xiang SD, Scalzo-Inguanti K, Minigo G, Park A, Hardy CL, Plebanski M. Promising particle-based vaccines in cancer therapy. Expert Rev Vaccines 2008; 7:1103-19.
30. Bausero MA, Panoskaltsismortari A, Blazar BR, Katsanis E. Effective immunization against neuroblastoma using doubletransduced tumor cells secreting GM-CSF interferon-gamma. J Immunother 1996; 19:113-17.
31. Soiffer R, Lynch T, Mihm M, et al. Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte- macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma. Proc Natl Acad Sci 1998; 95:131-41.
32. T. Satoh, T. Saika, S. Ebara, et al. Prolonged, NK cell-mediated antitumor effects of suicide gene therapy combined with monocyte chemoattractant Protein-1 against hepatocellular carcinoma. Cancer Res 2003; 63:7853-60.
33. Allavena P, Signorelli M, Chieppa M, et al. Antiinflammatory properties of the novel antitumor agent yondelis (trabectedin): inhibition of macrophage differentiation and cytokine production. Cancer Res 2005; 65:2964-71. (Pubitemid 40490102)
34. Singh N, Singh S, Shrivastava P. Effect of Tinospora cordifolia on the antitumor activity of tumor-associated macrophages-derived dendritic cells. Immunopharmacol Immunotoxicol 2005; 27:1-14. (Pubitemid 40389446)
35. Ghosh D, Maiti TK. Effects of native and heat-denatured Abrus agglutinin on tumor-associated macrophages in Dalton's lymphoma mice. Immunobiology 2007; 212:667-73. (Pubitemid 47377719)
36. Guruvayoorappan C, Kuttan G. Apoptotic effect of Biophytum sensitivum on B16F-10 cells and its regulatory effects on nitric oxide and cytokine production on tumor-associated macrophages. Integr Cancer Ther 2007; 6:373-80. (Pubitemid 350136017)
37. Guruvayoorappan C, Kuttan G. Amentoflavone stimulates apoptosis in B16F-10 melanoma cells by regulating bcl-2, p53 as well as caspase-3 genes and regulates the nitric oxide aswell as proinflammatory cytokine production inB16F-10 melanoma cells, tumor associated macrophages and peritoneal macrophages. J Exp Therapeut Oncol 2008; 7:207-18.
38. Manthey CL, Perera PY, Salkowski CA, Vogel SN. Taxol provides a second signal for murine macrophage tumoricidal activity. J Immunol 1994; 152:825-31. (Pubitemid 24072987)
39. Bogdan C, Ding A. Taxol, a microtubule-stabilizing antineoplastic agent, induces expression of tumor necrosis factor alpha and interleukin-1 in macrophages. J Leukoc Biol 1992; 52:119-21.
40. Giraudo E, Inoue M, Hanahan D. An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis. J Clin Invest 2004; 114:623-33. (Pubitemid 39578752)
41. Walker TM, Burger CJ, Elgert KD. Tumor growth alters T cell and macrophage production of and responsiveness to granulocytemacrophage colony-stimulating factor: partial dysregulation through interleukin-10. Cell Immunol 1994; 154:342-57. (Pubitemid 24115137)
42. Kumar S, Deepak P, Acharya A. Hsp70 induces Th1 polarization through tumor-associated macrophages in a T-cell lymphoma. Neoplasma 2007; 54:113-22.
43. Kumar S, Ajitabh K, Deepak P, Acharya A. Autologous Hsp70 immunization induces anti-tumor immunity and increases longevity and survival of tumor-bearing mice. Neoplasma 2009; 56:257-66.