메뉴 건너뛰기




Volumn 133, Issue 6, 2013, Pages 1334-1344

Dysfunctional endothelial cells directly stimulate cancer inflammation and metastasis

Author keywords

angiogenesis; endothelium; inflammation; metastasis

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; STAT3 PROTEIN;

EID: 84879892308     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28146     Document Type: Article
Times cited : (94)

References (50)
  • 1
    • 0041767435 scopus 로고    scopus 로고
    • Endothelial cell functions
    • Michiels C,. Endothelial cell functions. J Cell Physiol 2003; 196: 430-43.
    • (2003) J Cell Physiol , vol.196 , pp. 430-443
    • Michiels, C.1
  • 2
    • 0029796778 scopus 로고    scopus 로고
    • Endogenous cell seeding. Remnant endothelium after stenting enhances vascular repair
    • Rogers C, Parikh S, Seifert P, et al. Endogenous cell seeding. Remnant endothelium after stenting enhances vascular repair. Circulation 1996; 94: 2909-14.
    • (1996) Circulation , vol.94 , pp. 2909-2914
    • Rogers, C.1    Parikh, S.2    Seifert, P.3
  • 3
    • 0029088896 scopus 로고
    • Tissue engineered perivascular endothelial cell implants regulate vascular injury
    • Nathan A, Nugent MA, Edelman ER,. Tissue engineered perivascular endothelial cell implants regulate vascular injury. Proc Natl Acad Sci USA 1995; 92: 8130-4.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8130-8134
    • Nathan, A.1    Nugent, M.A.2    Edelman, E.R.3
  • 4
    • 44349141969 scopus 로고    scopus 로고
    • Tissue-engineered endothelial and epithelial implants differentially and synergistically regulate airway repair
    • Zani BG, Kojima K, Vacanti CA, et al. Tissue-engineered endothelial and epithelial implants differentially and synergistically regulate airway repair. Proc Natl Acad Sci USA 2008; 105: 7046-51.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 7046-7051
    • Zani, B.G.1    Kojima, K.2    Vacanti, C.A.3
  • 5
    • 79957894276 scopus 로고    scopus 로고
    • Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
    • Carmeliet P, Jain RK,. Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases. Nat Rev Drug Discov 2011; 10: 417-27.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 417-427
    • Carmeliet, P.1    Jain, R.K.2
  • 6
    • 78751656154 scopus 로고    scopus 로고
    • Stromal endothelial cells directly influence cancer progression
    • Franses JW, Baker AB, Chitalia VC, et al. Stromal endothelial cells directly influence cancer progression. Sci Transl Med 2011; 3: 66ra5.
    • (2011) Sci Transl Med , vol.3
    • Franses, J.W.1    Baker, A.B.2    Chitalia, V.C.3
  • 7
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby P,. Inflammation in atherosclerosis. Nature 2002; 420: 868-74.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 8
    • 0037112468 scopus 로고    scopus 로고
    • Mechanical signaling and the cellular response to extracellular matrix in angiogenesis and cardiovascular physiology
    • Ingber DE,. Mechanical signaling and the cellular response to extracellular matrix in angiogenesis and cardiovascular physiology. Circ Res 2002; 91: 877-87.
    • (2002) Circ Res , vol.91 , pp. 877-887
    • Ingber, D.E.1
  • 9
    • 0032581277 scopus 로고    scopus 로고
    • Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
    • Carmeliet P, Dor Y, Herbert JM, et al. Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 1998; 394: 485-90.
    • (1998) Nature , vol.394 , pp. 485-490
    • Carmeliet, P.1    Dor, Y.2    Herbert, J.M.3
  • 10
    • 9244227134 scopus 로고    scopus 로고
    • Stromal fibroblasts in cancer initiation and progression
    • Bhowmick NA, Neilson EG, Moses HL,. Stromal fibroblasts in cancer initiation and progression. Nature 2004; 432: 332-7.
    • (2004) Nature , vol.432 , pp. 332-337
    • Bhowmick, N.A.1    Neilson, E.G.2    Moses, H.L.3
  • 11
    • 60549098432 scopus 로고    scopus 로고
    • Role of TNF-alpha in vascular dysfunction
    • Zhang H, Park Y, Wu J, et al. Role of TNF-alpha in vascular dysfunction. Clin Sci (Lond) 2009; 116: 219-30.
    • (2009) Clin Sci (Lond) , vol.116 , pp. 219-230
    • Zhang, H.1    Park, Y.2    Wu, J.3
  • 12
    • 77954333963 scopus 로고    scopus 로고
    • Vascular endothelial growth factors and vascular permeability
    • Bates DO,. Vascular endothelial growth factors and vascular permeability. Cardiovasc Res 2010; 87: 262-71.
    • (2010) Cardiovasc Res , vol.87 , pp. 262-271
    • Bates, D.O.1
  • 13
    • 33749332105 scopus 로고    scopus 로고
    • Gene expression of tumor angiogenesis dissected: Specific targeting of colon cancer angiogenic vasculature
    • van Beijnum JR, Dings RP, van der Linden E, et al. Gene expression of tumor angiogenesis dissected: specific targeting of colon cancer angiogenic vasculature. Blood 2006; 108: 2339-48.
    • (2006) Blood , vol.108 , pp. 2339-2348
    • Van Beijnum, J.R.1    Dings, R.P.2    Van Der Linden, E.3
  • 14
    • 34347234200 scopus 로고    scopus 로고
    • The chemoinvasion assay: A method to assess tumor and endothelial cell invasion and its modulation
    • Albini A, Benelli R,. The chemoinvasion assay: a method to assess tumor and endothelial cell invasion and its modulation. Nat Protoc 2007; 2: 504-11.
    • (2007) Nat Protoc , vol.2 , pp. 504-511
    • Albini, A.1    Benelli, R.2
  • 15
    • 70449109147 scopus 로고    scopus 로고
    • Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma
    • Meylan E, Dooley AL, Feldser DM, et al. Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma. Nature 2009; 462: 104-7.
    • (2009) Nature , vol.462 , pp. 104-107
    • Meylan, E.1    Dooley, A.L.2    Feldser, D.M.3
  • 16
    • 0027970092 scopus 로고
    • Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
    • O'Reilly MS, Holmgren L, Shing Y, et al. Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 1994; 79: 315-28.
    • (1994) Cell , vol.79 , pp. 315-328
    • O'Reilly, M.S.1    Holmgren, L.2    Shing, Y.3
  • 17
    • 0034612309 scopus 로고    scopus 로고
    • Perlecan is required to inhibit thrombosis after deep vascular injury and contributes to endothelial cell-mediated inhibition of intimal hyperplasia
    • Nugent MA, Nugent HM, Iozzo RV, et al. Perlecan is required to inhibit thrombosis after deep vascular injury and contributes to endothelial cell-mediated inhibition of intimal hyperplasia. Proc Natl Acad Sci USA 2000; 97: 6722-7.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 6722-6727
    • Nugent, M.A.1    Nugent, H.M.2    Iozzo, R.V.3
  • 18
    • 34547676391 scopus 로고    scopus 로고
    • Endothelial-to-mesenchymal transition contributes to cardiac fibrosis
    • Zeisberg EM, Tarnavski O, Zeisberg M, et al. Endothelial-to-mesenchymal transition contributes to cardiac fibrosis. Nat Med 2007; 13: 952-61.
    • (2007) Nat Med , vol.13 , pp. 952-961
    • Zeisberg, E.M.1    Tarnavski, O.2    Zeisberg, M.3
  • 19
    • 55249126800 scopus 로고    scopus 로고
    • The role of endothelial-to-mesenchymal transition in cancer progression
    • Potenta S, Zeisberg E, Kalluri R,. The role of endothelial-to-mesenchymal transition in cancer progression. Br J Cancer 2008; 99: 1375-9.
    • (2008) Br J Cancer , vol.99 , pp. 1375-1379
    • Potenta, S.1    Zeisberg, E.2    Kalluri, R.3
  • 20
    • 36849039660 scopus 로고    scopus 로고
    • IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland
    • Sansone P, Storci G, Tavolari S, et al. IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland. J Clin Invest 2007; 117: 3988-4002.
    • (2007) J Clin Invest , vol.117 , pp. 3988-4002
    • Sansone, P.1    Storci, G.2    Tavolari, S.3
  • 21
    • 70350500225 scopus 로고    scopus 로고
    • STATs in cancer inflammation and immunity: A leading role for STAT3
    • Yu H, Pardoll D, Jove R,. STATs in cancer inflammation and immunity: a leading role for STAT3. Nat Rev Cancer 2009; 9: 798-809.
    • (2009) Nat Rev Cancer , vol.9 , pp. 798-809
    • Yu, H.1    Pardoll, D.2    Jove, R.3
  • 22
    • 0030772376 scopus 로고    scopus 로고
    • Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo
    • Pierce JW, Schoenleber R, Jesmok G, et al. Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J Biol Chem 1997; 272: 21096-103.
    • (1997) J Biol Chem , vol.272 , pp. 21096-21103
    • Pierce, J.W.1    Schoenleber, R.2    Jesmok, G.3
  • 23
    • 24644515305 scopus 로고    scopus 로고
    • Matrix embedding alters the immune response against endothelial cells in vitro and in vivo
    • Methe H, Nugent HM, Groothuis A, et al. Matrix embedding alters the immune response against endothelial cells in vitro and in vivo. Circulation 2005; 112: I89-I95.
    • (2005) Circulation , vol.112
    • Methe, H.1    Nugent, H.M.2    Groothuis, A.3
  • 24
    • 75149149879 scopus 로고    scopus 로고
    • Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors
    • Butler JM, Kobayashi H, Rafii S,. Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors. Nat Rev Cancer 2010; 10: 138-46.
    • (2010) Nat Rev Cancer , vol.10 , pp. 138-146
    • Butler, J.M.1    Kobayashi, H.2    Rafii, S.3
  • 25
    • 0027375595 scopus 로고
    • Density-dependent endothelial cell production of an inhibitor of smooth muscle cell growth
    • Dodge AB, Lu X, D'Amore PA,. Density-dependent endothelial cell production of an inhibitor of smooth muscle cell growth. J Cell Biochem 1993; 53: 21-31.
    • (1993) J Cell Biochem , vol.53 , pp. 21-31
    • Dodge, A.B.1    Lu, X.2    D'Amore, P.A.3
  • 26
    • 0027378730 scopus 로고
    • Vascular cell-derived heparan sulfate shows coupled inhibition of basic fibroblast growth factor binding and mitogenesis in vascular smooth muscle cells
    • Nugent MA, Karnovsky MJ, Edelman ER,. Vascular cell-derived heparan sulfate shows coupled inhibition of basic fibroblast growth factor binding and mitogenesis in vascular smooth muscle cells. Circ Res 1993; 73: 1051-60.
    • (1993) Circ Res , vol.73 , pp. 1051-1060
    • Nugent, M.A.1    Karnovsky, M.J.2    Edelman, E.R.3
  • 27
    • 0036488496 scopus 로고    scopus 로고
    • Specialization of tumour vasculature
    • Ruoslahti E,. Specialization of tumour vasculature. Nat Rev Cancer 2002; 2: 83-90.
    • (2002) Nat Rev Cancer , vol.2 , pp. 83-90
    • Ruoslahti, E.1
  • 28
    • 36048982445 scopus 로고    scopus 로고
    • Tumor blood vessels, a difficult hurdle for infiltrating leukocytes
    • Castermans K, Griffioen AW,. Tumor blood vessels, a difficult hurdle for infiltrating leukocytes. Biochim Biophys Acta 2007; 1776: 160-74.
    • (2007) Biochim Biophys Acta , vol.1776 , pp. 160-174
    • Castermans, K.1    Griffioen, A.W.2
  • 29
    • 33745005732 scopus 로고    scopus 로고
    • Dysregulation of the endothelial cellular response to oxidative stress in cancer
    • Houle F, Huot J,. Dysregulation of the endothelial cellular response to oxidative stress in cancer. Mol Carcinog 2006; 45: 362-7.
    • (2006) Mol Carcinog , vol.45 , pp. 362-367
    • Houle, F.1    Huot, J.2
  • 30
    • 49649125325 scopus 로고    scopus 로고
    • Tumor-derived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro
    • Ghosh K, Thodeti CK, Dudley AC, et al. Tumor-derived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro. Proc Natl Acad Sci USA 2008; 105: 11305-10.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 11305-11310
    • Ghosh, K.1    Thodeti, C.K.2    Dudley, A.C.3
  • 31
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov SI, Greten FR, Karin M,. Immunity, inflammation, and cancer. Cell 2010; 140: 883-99.
    • (2010) Cell , vol.140 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 32
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA,. Hallmarks of cancer: the next generation. Cell 2011; 144: 646-74.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 33
    • 70450189795 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis: From pathophysiology to practice
    • Libby P, Ridker PM, Hansson GK,. Inflammation in atherosclerosis: from pathophysiology to practice. J Am Coll Cardiol 2009; 54: 2129-38.
    • (2009) J Am Coll Cardiol , vol.54 , pp. 2129-2138
    • Libby, P.1    Ridker, P.M.2    Hansson, G.K.3
  • 34
    • 69249205739 scopus 로고    scopus 로고
    • Obesity, inflammation, and atherosclerosis
    • Rocha VZ, Libby P,. Obesity, inflammation, and atherosclerosis. Nat Rev Cardiol 2009; 6: 399-409.
    • (2009) Nat Rev Cardiol , vol.6 , pp. 399-409
    • Rocha, V.Z.1    Libby, P.2
  • 35
    • 76349096670 scopus 로고    scopus 로고
    • Cancer-associated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-kappaB-dependent manner
    • Erez N, Truitt M, Olson P, et al. Cancer-associated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-kappaB-dependent manner. Cancer Cell 2010; 17: 135-47.
    • (2010) Cancer Cell , vol.17 , pp. 135-147
    • Erez, N.1    Truitt, M.2    Olson, P.3
  • 36
    • 84867132769 scopus 로고    scopus 로고
    • Tumor endothelial inflammation predicts clinical outcome in diverse human cancers
    • Pitroda SP, Zhou T, Sweis RF, et al. Tumor endothelial inflammation predicts clinical outcome in diverse human cancers. PLoS One 2012; 7: e46104.
    • (2012) PLoS One , vol.7
    • Pitroda, S.P.1    Zhou, T.2    Sweis, R.F.3
  • 37
    • 64849104716 scopus 로고    scopus 로고
    • Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription
    • Ashall L, Horton CA, Nelson DE, et al. Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription. Science 2009; 324: 242-6.
    • (2009) Science , vol.324 , pp. 242-246
    • Ashall, L.1    Horton, C.A.2    Nelson, D.E.3
  • 38
    • 77749298990 scopus 로고    scopus 로고
    • Molecular mechanisms of system control of NF-kappaB signaling by IkappaBalpha
    • Ferreiro DU, Komives EA,. Molecular mechanisms of system control of NF-kappaB signaling by IkappaBalpha. Biochemistry 2010; 49: 1560-7.
    • (2010) Biochemistry , vol.49 , pp. 1560-1567
    • Ferreiro, D.U.1    Komives, E.A.2
  • 39
    • 0036957638 scopus 로고    scopus 로고
    • Perivascular endothelial implants inhibit intimal hyperplasia in a model of arteriovenous fistulae: A safety and efficacy study in the pig
    • Nugent HM, Groothuis A, Seifert P, et al. Perivascular endothelial implants inhibit intimal hyperplasia in a model of arteriovenous fistulae: a safety and efficacy study in the pig. J Vasc Res 2002; 39: 524-33.
    • (2002) J Vasc Res , vol.39 , pp. 524-533
    • Nugent, H.M.1    Groothuis, A.2    Seifert, P.3
  • 40
    • 79952392467 scopus 로고    scopus 로고
    • Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression
    • Bissell MJ, Hines WC,. Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression. Nat Med 2011; 17: 320-9.
    • (2011) Nat Med , vol.17 , pp. 320-329
    • Bissell, M.J.1    Hines, W.C.2
  • 41
    • 36849012237 scopus 로고    scopus 로고
    • Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas
    • Gao SP, Mark KG, Leslie K, et al. Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas. J Clin Invest 2007; 117: 3846-56.
    • (2007) J Clin Invest , vol.117 , pp. 3846-3856
    • Gao, S.P.1    Mark, K.G.2    Leslie, K.3
  • 42
    • 77958501473 scopus 로고    scopus 로고
    • DNA damage-mediated induction of a chemoresistant niche
    • Gilbert LA, Hemann MT,. DNA damage-mediated induction of a chemoresistant niche. Cell 2010; 143: 355-66.
    • (2010) Cell , vol.143 , pp. 355-366
    • Gilbert, L.A.1    Hemann, M.T.2
  • 43
    • 0034036837 scopus 로고    scopus 로고
    • Endothelial heparan sulfate is necessary but not sufficient for control of vascular smooth muscle cell growth
    • Ettenson DS, Koo EW, Januzzi JL, et al. Endothelial heparan sulfate is necessary but not sufficient for control of vascular smooth muscle cell growth. J Cell Physiol 2000; 184: 93-100.
    • (2000) J Cell Physiol , vol.184 , pp. 93-100
    • Ettenson, D.S.1    Koo, E.W.2    Januzzi, J.L.3
  • 44
    • 41149138113 scopus 로고    scopus 로고
    • Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer
    • Jain RK,. Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer. Nat Rev Cancer 2008; 8: 309-16.
    • (2008) Nat Rev Cancer , vol.8 , pp. 309-316
    • Jain, R.K.1
  • 45
    • 60649087564 scopus 로고    scopus 로고
    • Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
    • Ebos JM, Lee CR, Cruz-Munoz W, et al. Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell 2009; 15: 232-9.
    • (2009) Cancer Cell , vol.15 , pp. 232-239
    • Ebos, J.M.1    Lee, C.R.2    Cruz-Munoz, W.3
  • 46
    • 60649106195 scopus 로고    scopus 로고
    • Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
    • Paez-Ribes M, Allen E, Hudock J, et al. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 2009; 15: 220-31.
    • (2009) Cancer Cell , vol.15 , pp. 220-231
    • Paez-Ribes, M.1    Allen, E.2    Hudock, J.3
  • 47
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J,. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971; 285: 1182-6.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 48
    • 0030484797 scopus 로고    scopus 로고
    • Reciprocal paracrine interactions between tumour cells and endothelial cells: The 'angiogenesis progression' hypothesis
    • Rak J, Filmus J, Kerbel RS,. Reciprocal paracrine interactions between tumour cells and endothelial cells: the 'angiogenesis progression' hypothesis. Eur J Cancer 1996; 32A: 2438-50.
    • (1996) Eur J Cancer , vol.32 A , pp. 2438-2450
    • Rak, J.1    Filmus, J.2    Kerbel, R.S.3
  • 49
    • 33746791465 scopus 로고    scopus 로고
    • Interaction of KAI1 on tumor cells with DARC on vascular endothelium leads to metastasis suppression
    • Bandyopadhyay S, Zhan R, Chaudhuri A, et al. Interaction of KAI1 on tumor cells with DARC on vascular endothelium leads to metastasis suppression. Nat Med 2006; 12: 933-8.
    • (2006) Nat Med , vol.12 , pp. 933-938
    • Bandyopadhyay, S.1    Zhan, R.2    Chaudhuri, A.3
  • 50
    • 33846029123 scopus 로고    scopus 로고
    • A perivascular niche for brain tumor stem cells
    • Calabrese C, Poppleton H, Kocak M, et al. A perivascular niche for brain tumor stem cells. Cancer Cell 2007; 11: 69-82.
    • (2007) Cancer Cell , vol.11 , pp. 69-82
    • Calabrese, C.1    Poppleton, H.2    Kocak, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.