Thiopyrazole preactivated chitosan: Combining mucoadhesion and drug delivery

Acta Biomaterialia

Volumn 9, Issue 5, 2013, Pages 6585-6593

  Müller, Christiane ^a   Ma, Benjamin N ^a   Gust, Ronald ^a   Bernkop Schnürch, Andreas ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

Biomaterials; Drug delivery; Mucoadhesion; Thiol disulfide exchange; Thiomers

Indexed keywords

BIOMATERIALS; CHITOSAN; CONTROLLED DRUG DELIVERY; COVALENT BONDS; CYTOTOXICITY; DEXTRAN; SULFUR COMPOUNDS; TARGETED DRUG DELIVERY;

CHITOSAN DERIVATIVES; DISULFIDE BOND FORMATION; FLUORESCEIN ISOTHIOCYANATE DEXTRANS; INTESTINAL MUCOSA; MUCOADHESION; MUCOADHESIVES; SYNTHESISED; THIOGLYCOLIC ACID; THIOL DISULFIDE EXCHANGE; THIOMERS;

AMINO ACIDS;

CHITOSAN; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; PYRAZOLE DERIVATIVE; THIOPYRAZOLE; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; CELL STRAIN CACO 2; CELL VIABILITY; CONTROLLED STUDY; CROSS LINKING; DISULFIDE BOND; DRUG BIOAVAILABILITY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; HUMAN; HUMAN CELL; HYDROPHILICITY; IN VITRO STUDY; INCUBATION TIME; LIPOPHILICITY; MEMBRANE PERMEABILITY; MUCOADHESION; OXIDATION REDUCTION REACTION; OXIDATIVE COUPLING; PH; PRIORITY JOURNAL; TABLET DISINTEGRATION; TIGHT JUNCTION; VISCOMETRY; WATER ABSORPTION; WATER TRANSPORT;

SUS;

EID: 84879883429     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2013.01.008     Document Type: Article

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