S-protected thiolated chitosan: Synthesis and in vitro characterization

Carbohydrate Polymers

Volumn 90, Issue 2, 2012, Pages 765-772

  Dünnhaupt, Sarah ^a   Barthelmes, Jan ^a   Thurner, Clemens C ^b   Waldner, Claudia ^b   Sakloetsakun, Duangkamon ^c   Bernkop Schnürch, Andreas ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b Thiomatrix Forschungs und Beratungs GmbH   (Austria)

^c KHON KAEN UNIVERSITY   (Thailand)

Author keywords

Disulfide bond formation; Mucoadhesion; S protected thiomers; Stability; Thiomers

Indexed keywords

CONTROLLED RELEASE; DISULFIDE BOND FORMATION; DRUG DELIVERY SYSTEM; DRUG RELEASE; FREE THIOL GROUP; HYDROPHOBIC RESIDUES; IN-VITRO; INTESTINAL MUCOSA; MATRIX TABLET; MODEL PEPTIDES; MUCOADHESION; MUCOADHESIVE POLYMERS; MUCOADHESIVE PROPERTIES; SWELLING BEHAVIOR; THIOL GROUPS; THIOLATED CHITOSAN; THIOMERS;

CONVERGENCE OF NUMERICAL METHODS; COVALENT BONDS; DRUG DELIVERY; DRUG PRODUCTS; MULTILAYERS; POLYMERS;

CHITOSAN;

CHITOSAN; FERTILITY PROMOTING AGENT; LEUPRORELIN; THIOL DERIVATIVE; WATER;

ARTICLE; BIOLOGICAL MODEL; CELL STRAIN CACO 2; CHEMISTRY; COMPARATIVE STUDY; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG SCREENING; HUMAN; METABOLISM; MUCOSA; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TABLET;

CACO-2 CELLS; CHITOSAN; DRUG DELIVERY SYSTEMS; DRUG EVALUATION, PRECLINICAL; FERTILITY AGENTS, FEMALE; HUMANS; LEUPROLIDE; MODELS, BIOLOGICAL; MUCOUS MEMBRANE; STRUCTURE-ACTIVITY RELATIONSHIP; SULFHYDRYL COMPOUNDS; TABLETS; WATER;

EID: 84864492842     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2012.05.028     Document Type: Article

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