Involvement of p-CREB and phase II detoxifying enzyme system in neuroprotection mediated by the flavonoid calycopterin isolated from Dracocephalum kotschyi

Phytomedicine

Volumn 20, Issue 10, 2013, Pages 939-946

  Sarvestani, Nazanin Namazi ^a   Khodagholi, Fariba ^a   Ansari, Niloufar ^a   Farimani, Mahdi Moridi ^b  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHAHID BEHESHTI UNIVERSITY   (Iran)

Author keywords

Calycopterin; CREB; Nrf2; Oxidative stress; PC12 cell

Indexed keywords

5,5' DITHIOBIS(2 NITROBENZOIC ACID); CALYCOPTERIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOCHROME C; DNA; FLAVONOID; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; HEME OXYGENASE 1; HYDROGEN PEROXIDE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL LYSATE; CELL SURVIVAL; COLORIMETRY; COMET ASSAY; CONTROLLED STUDY; CYTOSOL; DRACOCEPHALUM KOTSCHYI; DRUG ISOLATION; ENZYME ACTIVITY; HOMEOSTASIS; LAMIACEAE; MITOCHONDRIAL MEMBRANE POTENTIAL; MORPHOLOGY; NEUROPROTECTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; WESTERN BLOTTING; WHOLE CELL;

Γ-GCS; Γ-GLUTAMYLCYSTEINE SYNTHETASE; 4-(2-HYDROXYETHYL)-PIPERAZINEETHANESULFONIC ACID; ANTIOXIDANT RESPONSE ELEMENT; ARE; BBB; BLOOD BRAIN BARRIER; BOVINE SERUM ALBUMIN; BSA; CALYCOPTERIN; CAMP RESPONSE ELEMENT BINDING PROTEIN; CREB; DITHIONITROBENZOIC ACID; DTNB; ECL; ELECTROCHEMILUMINESCENCE; HEMEOXYGENASE-1; HEPES; HO-1; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY TRANSITION; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MMP; MPT; MPTP; NADH; NBT; NERVE GROWTH FACTOR; NGF; NICOTINAMIDE ADENINE DINUCLEOTIDE; NITROBLUE TETRAZOLIUM; NRF2; NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 2; OXIDATIVE STRESS; PC12 CELL; PHENAZINE METHOSULPHATE; PHENYLMETHYLSULFONYL FLUORIDE; PMS; PMSF; REACTIVE OXYGEN SPECIES; ROS; SOD; SUPEROXIDE DISMUTASE;

ANIMALS; COMET ASSAY; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DRUG EVALUATION, PRECLINICAL; FLAVONES; LAMIACEAE; METABOLIC DETOXICATION, PHASE II; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; PC12 CELLS; RATS;

DRACOCEPHALUM KOTSCHYI;

EID: 84879881001     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.03.013     Document Type: Article

References (44)

1. E.S. Alnemri Mammalian cell death proteases: a family of highly conserved aspartate specific cysteine proteases Journal of Biochemistry 64 1997 33 42
2. N. Ansari, F. Khodagholi, and M. Amini 2-Ethoxy-4,5-diphenyl-1,3-oxazine- 6-one activates the Nrf2/HO-1 axis and protects against oxidative stress-induced neuronal death European Journal of Pharmacology 658 2011 84 90
3. B.S. Berlett, and E.R. Stadtman Protein oxidation in aging, disease and oxidative stress Journal of Biological Chemistry 272 1997 20313 20316
4. M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Analytical Biochemistry 72 1976 248 254
5. J. Cai, J. Yang, and D.P. Jones Mitochondrial control of apoptosis: the role of cytochrome c Biochimica et Biophysica Acta 1366 1-2 2008 139 149
6. J.C. Cheng Potential role of CREB as a prognostic marker in acute myeloid leukemia Future Oncology 3 4 2007 475 480
7. S.B. Cullinan, and J.A. Diehl PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress Journal of Biological Chemistry 279 2004 20108 20117
8. S.B. Cullinan, and J.A. Diehl Coordination of ER and oxidative stress signaling: the PERK/Nrf2 signaling pathway International Journal of Biochemistry & Cell Biology 38 3 2006 317 332
9. F. Dajas, F. Rivera-Megret, F. Blasina, F. Arredondo, J.A. Abin-Carriquiry, G. Costa, C. Echeverry, L. Lafon, H. Heizen, M. Ferreira, and A. Morquio Neuroprotection by flavonoids Brazilian Journal of Medical and Biological Research 36 2003 1613 1620
10. G.L. Ellman Tissue sulfhydryl group Archives of Biochemistry and Biophysics 82 1959 70 77
11. N. Faham, K. Javidnia, M. Bahmani, and Z. Amirghofran Calycopterin, an immunoinhibitory compound from the extract of Dracocephalum Kotschyi Phytotherapy Research 22 2008 1154 1158
12. M.M. Farimani, N. Namazi Sarvestani, N. Ansari, and F. Khodagholi Calycopterin promotes survival and outgrowth of neuron-like PC12 cells by attenuation of oxidative- and ER-stress-induced apoptosis along with inflammatory response Chemical Research in Toxicology 24 2011 2280 2292
13. A. Franko CREB-1alpha is recruited to and mediates upregulation of the cytochrome c promoter during enhanced mitochondrial biogenesis accompanying skeletal muscle differentiation Molecular and Cellular Biology 28 7 2008 2446 2459
14. G. Galati, T. Chan, B. Wu, and P.J. O'Brien Glutathione-dependent generation of reactive oxygen species by the peroxidase-catalyzed redox cycling of flavonoids Chemical Research in Toxicology 12 6 1999 521 525
15. L.A. Greene, and A.S. Trischler PC12 pheochromocytoma cells in neurobiological research Advances in Cellular Neurobiology 3 1982 373 414
16. A.P. Halestrap, and C. Brenner The adenine nucleotide translocate: a central component of the mitochondrial permeability transition pore and key player in cell death Current Medicinal Chemistry 10 16 2003 1507 1525
17. P. Kakkar, B. Das, and P.N. Viswanathan A modified spectrophotometric assay of superoxide dismutase Indian Journal of Biochemistry and Biophysics 21 1984 4551 4563
18. Y. Katoh, K. Itoh, E. Yoshida, M. Miyagishi, A. Fukamizu, and M. Yamamoto Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription Genes to Cells 6 10 2001 857 868
19. M. Kaulich, F. Streicher, R. Mayer, I. Müller, and C.E. Müller Flavonoids - novel lead compounds for the development of P2Y2 receptor antagonists Drug Development Research 59 1 2003 72 81
20. G. Kroemer, L. Galluzzi, and C. Brenner Mitochondrial membrane permeabilization in cell death Physiological Reviews 87 2007 99 163
21. J. Lee, and J.A. Johnson An important role of Nrf2-ARE pathway in cellular defense mechanism Journal of Biochemistry and Molecular Biology 37 2004 139 143
22. J. Lee, C. Kim, D. Simon, L. Aminova, A. Andreyev, Y. Kushnareva, A. Murphy, B.E. Kim, K. Ginty, D.D. Ferrante, R.J. Ryu, and H.R.R. Ratan Mitochondrial cyclic AMP response element-binding protein (CREB) mediates mitochondrial gene expression and neuronal survival Journal of Biological Chemistry 280 49 2005 40398 40401
23. H.Y. Li, S.Y. Wu, and N. Shi Transcription factor Nrf2 activation by deltamethrin in PC12 cells: involvement of ROS Toxicology Letters 171 1-2 2007 87 98
24. B. Mazurek Pathogenesis and treatment of presbyacusis. Current status and future perspectives HNO 56 4 2008 429 432 434-435
25. M. Mihara, and U.M. Moll Detection of mitochondrial localization of p 53 Methods in Molecular Biology 234 2003 203 209
26. S. Pavlica, and R. Gebhardt Protective effects of flavonoids and two metabolites against oxidative stress in neuronal PC12 cells Life Sciences 86 2010 79 86
27. C.A. Piantadosi Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1 Circulation Research 103 11 2008 1232 1240
28. P.G. Pietta Flavonoids as antioxidant Journal of Natural Products 63 7 2000 1035 1042
29. M.C. Poppe, H. Reimertz, and A.J. Dussmann Dissipation of potassium and proton gradient inhibits mitochondrial hyperpolarization and cytochrome c release during neural apoptosis Journal of Neuroscience 21 2001 4551 4563
30. R.S. Shoal, and R. Weindruch Oxidative stress, caloric restriction and aging Science 273 5271 1996 59 63
31. A.N. Ratnagiriswaran, K.B. Sehra, and K. Venkataraman The anthelminthic constituent of the leaves of calycopterin floribunda Biochemical Journal 28 1934 1964 1967
32. I. Rietjens, M.G. Boersma, L. Haa, B. Spenkelink, H.M. Awad, N.H.P. Cnubben, J. van Zanden, H. Woude, G.M. Alink, and J.H. Koeman The pro-oxidant chemistry of the natural antioxidants vitamin C, vitamin E, carotenoids and flavonoids Environmental Toxicology and Pharmacology 11 2002 321 333
33. K. Sakamoto, K. Karelina, and K. Obrietan CREB: a multifaceted regulator of neuronal plasticity and protection Journal of Neurochemistry 116 2011 1 9
34. N. Sasaki, T. Toda, T. Kaneko, N. BABA, and M. Matsuo Flavonoids suppress the cytotoxicity of linoleic acid hydroperoxide toward PC12 cells Biological and Pharmaceutical Bulletin 25 8 2002 1093 1096
35. R.S. Scarpulla Transcriptional activators and coactivators in the nuclear control of mitochondrial function in mammalian cells Gene 286 2001 81 89
36. G. Shen, V. Hebbar, S. Nair, C. Xu, W. Li, W. Lin, Y. Keum, J. Han, M.A. Gallo, and T. Kong Regulation of Nrf2 transactivation domain activity Journal of Biological Chemistry 279 22 2004 23052 23060
37. C. Stefanneli, F. Bonavita, I. Stanic, G. Farruggia, E. Falcieri, I. Robiuffo, C. Pignatti, C. Muscari, C. Rossoni, C. Guarnieri, and C.M. Caldarera ATP depletion inhibits glucocorticoid-induced thymocyte apoptosis Biochemical Journal 322 1997 909 917
38. R.R. Tice, E. Agurell, D. Anderson, B. Burlinson, A. Hartmann, H. Kobayashi, Y. Miyamae, E. Rojas, J.-C. Ryu, and Y.F. Sasaki Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing Environmental and Molecular Mutagenesis 35 2000 206 221
39. D. Trachootham, W. Lu, M.A. Ogasawara, N. Rivera-Del Valle, and P. Huang Redox Regulation of Cell Survival Antioxidants & Redox Signaling 10 8 2008 1343 1374
40. S.K. Tusi, N. Ansari, M. Amini, A. Dehghani Amirabad, A. Shafiee, and F. Khodagholi Attenuation of NF-κB and activation of Nrf2 signaling by 1,2,4-triazine derivatives, protects neuron-like PC12 cells against apoptosis Apoptosis 15 2010 738 751
41. H. Wang, Y. Hu, and J.Z. Tsien Molecular and systems mechanisms of memory consolidation and storage Progress in Neurobiology 79 3 2006 123 135
42. C.C. Wu, and C.W. Hsieh Upregulation of endothelial heme oxygenase-1 expression through the activation of the JNK pathway by sublethal concentrations of acrolein Toxicology and Applied Pharmacology 214 3 2006 244 252
43. L.H. Yao, Y.M. Jing, J. Shi, F.A. Tomas-Barberan, N. Datta, R. Singanusong, and S.S. Chen Flavonoids in food and their health benefits Plant Foods for Human Nutrition 59 2004 113 122
44. N. Zamzami, and G. Kroemer Mitochondria in apoptosis. How Pandora's box opens Nature Reviews Molecular Cell Biology 2 2001 67 71