2-Ethoxy-4,5-diphenyl-1,3-oxazine-6-one activates the Nrf2/HO-1 axis and protects against oxidative stress-induced neuronal death

European Journal of Pharmacology

Volumn 658, Issue 2-3, 2011, Pages 84-90

  Ansari, Niloufar ^a,b   Khodagholi, Fariba ^a   Amini, Mohsen ^b  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Alzheimer's disease; Apoptosis; Nrf2; Oxazine derivative; Oxidative stress; PC12 cells

Indexed keywords

2 ETHOXY 4,5 DIPHENYL 1,3 OXAZIN 6 ONE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ACRIDINE ORANGE; CASPASE 3; CATALASE; ETHIDIUM BROMIDE; GLUTAMATE CYSTEINE LIGASE; HEAT SHOCK PROTEIN 70; HEME OXYGENASE 1; HYDROGEN PEROXIDE; NEUROPROTECTIVE AGENT; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; ENZYME INACTIVATION; LIPID PEROXIDATION; NERVE CELL DIFFERENTIATION; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN STABILITY; RAT; STAINING; UPREGULATION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CASPASE 3; CELL DEATH; ENZYME ACTIVATION; ENZYME INDUCTION; GENE EXPRESSION REGULATION; GLUTAMATE-CYSTEINE LIGASE; HEME OXYGENASE-1; HSP70 HEAT-SHOCK PROTEINS; HYDROGEN PEROXIDE; LIPID PEROXIDATION; NEURONS; NF-E2-RELATED FACTOR 2; OXAZINES; OXIDATIVE STRESS; PC12 CELLS; PROTEIN STABILITY; RATS;

EID: 79953803997     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.02.028     Document Type: Article

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