Genetic and epigenetic alterations of the LKB1 gene and their associations with mutations in TP53 and EGFR pathway genes in Korean non-small cell lung cancers

Lung Cancer

Volumn 81, Issue 2, 2013, Pages 194-199

  Lee, Su Man ^a   Choi, Jin Eun ^a   Na, Yeon Kyung ^a   Lee, Eun Jin ^a   Lee, Won Kee ^a   Choi, Yi Young ^a   Yoon, Ghil Suk ^a   Jeon, Hyo Sung ^a   Kim, Dong Sun ^a   Park, Jae Yong ^a,b  

^a Kyungpook National University School of Medicine   (South Korea)

^b Kyungpook National University Hospital   (South Korea)

Author keywords

Inactivation; LKB1; Non small cell lung cancer

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN KINASE LKB1; PROTEIN P53;

ADULT; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EPIGENETICS; FEMALE; GENE EXPRESSION; GENE MUTATION; GENETIC ASSOCIATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KOREA; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; METHYLATION; MICROSATELLITE MARKER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; SOMATIC MUTATION;

INACTIVATION; LKB1; NON-SMALL CELL LUNG CANCER;

ASIAN CONTINENTAL ANCESTRY GROUP; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; DNA METHYLATION; DOWN-REGULATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION; GENES, P53; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; MUTATION; PROMOTER REGIONS, GENETIC; PROTEIN-SERINE-THREONINE KINASES; RECEPTOR, EPIDERMAL GROWTH FACTOR; REPUBLIC OF KOREA; SIGNAL TRANSDUCTION;

EID: 84879879429     PISSN: 01695002     EISSN: 18728332     Source Type: Journal    
DOI: 10.1016/j.lungcan.2013.04.013     Document Type: Article

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