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Volumn 440, Issue 1, 2013, Pages 56-62

Amyloid-beta isoform metabolism quantitation by stable isotope-labeled kinetics

Author keywords

Alzheimer's disease; Amyloid beta isoforms; Cerebrospinal fluid; Mass spectrometry; Relative quantitation

Indexed keywords

BRAIN; CELL CULTURE; GLYCOPROTEINS; MASS SPECTROMETRY; METABOLISM; NEURODEGENERATIVE DISEASES; PEPTIDES;

EID: 84879836303     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2013.04.031     Document Type: Article
Times cited : (49)

References (28)
  • 1
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • DOI 10.1126/science.1072994
    • J. Hardy, D.J. Selkoe, The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics, Science 297 (2002) 353-356. (Pubitemid 34790756)
    • (2002) Science , vol.297 , Issue.5580 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 2
    • 0028169925 scopus 로고
    • Visualization of ab42(43) and ab40 in senile plaques with end-specific ab monoclonals: Evidence that an initially deposited species is ab42(43
    • T. Iwatsubo, A. Odaka, N. Suzuki, H. Mizusawa, N. Nukina, Y. Ihara, Visualization of Ab42(43) and Ab40 in senile plaques with end-specific Ab monoclonals: evidence that an initially deposited species is Ab42(43), Neuron 13 (1994) 45-53.
    • (1994) Neuron , vol.13 , pp. 45-53
    • Iwatsubo, T.1    Odaka, A.2    Suzuki, N.3    Mizusawa, H.4    Nukina, N.5    Ihara, Y.6
  • 7
    • 0028855851 scopus 로고
    • Dominant and differential deposition of distinct beta-Amyloid peptide species, abn3(pe), in senile plaques
    • T.C. Saido, T. Iwatsubo, D.M. Mann, H. Shimada, Y. Ihara, S. Kawashima, Dominant and differential deposition of distinct beta-Amyloid peptide species, AbN3(pE), in senile plaques, Neuron 14 (1995) 457-466.
    • (1995) Neuron , vol.14 , pp. 457-466
    • Saido, T.C.1    Iwatsubo, T.2    Mann, D.M.3    Shimada, H.4    Ihara, Y.5    Kawashima, S.6
  • 10
    • 33645775230 scopus 로고    scopus 로고
    • Determination of beta-Amyloid peptide signatures in cerebrospinal fluid using immunoprecipitation-mass spectrometry
    • E. Portelius, A. Westman-Brinkmalm, H. Zetterberg, K. Blennow, Determination of beta-Amyloid peptide signatures in cerebrospinal fluid using immunoprecipitation-mass spectrometry, J. Proteome Res. 5 (2006) 1010-1016.
    • (2006) J. Proteome Res. , vol.5 , pp. 1010-1016
    • Portelius, E.A.1    Zetterberg, H.2    Blennow, K.3
  • 11
    • 79961077443 scopus 로고    scopus 로고
    • Site-specific characterization of threonine, serine, and tyrosine glycosylations of amyloid precursor protein/amyloid-beta peptides in human cerebrospinal fluid
    • A. Halim, G. Brinkmalm, U. Ruetschi, A. Westman-Brinkmalm, E. Portelius, H. Zetterberg, K. Blennow, G. Larson, J. Nilsson, Site-specific characterization of threonine, serine, and tyrosine glycosylations of amyloid precursor protein/amyloid-beta peptides in human cerebrospinal fluid, Proc. Natl. Acad. Sci. USA 108 (2011) 11848-11853.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 11848-11853
    • Halim, A.1    Brinkmalm, G.2    Ruetschi, U.A.3    Portelius, E.4    Zetterberg, H.5    Blennow, K.6    Larson, G.7    Nilsson, J.8
  • 15
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease: Genes, proteins, and therapy
    • D.J. Selkoe, Alzheimer's disease: genes, proteins, and therapy, Physiol. Rev. 81 (2001) 741-766. (Pubitemid 32267077)
    • (2001) Physiological Reviews , vol.81 , Issue.2 , pp. 741-766
    • Selkoe, D.J.1
  • 16
  • 17
  • 18
    • 0027258525 scopus 로고
    • The carboxy terminus of the amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
    • DOI 10.1021/bi00069a001
    • J.T. Jarrett, E.P. Berger, P.T. Lansbury Jr., The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease, Biochemistry 32 (1993) 4693-4697. (Pubitemid 23162022)
    • (1993) Biochemistry , vol.32 , Issue.18 , pp. 4693-4697
    • Jarrett, J.T.1    Berger, E.P.2    Lansbury Jr., P.T.3
  • 19
    • 0028915895 scopus 로고
    • Amyloid beta protein (ab) in alzheimer's disease brain: Biochemical and immunocytochemical analysis with antibodies specific for forms ending at ab40 or ab42(43
    • S.A. Gravina, L. Ho, C.B. Eckman, K.E. Long, L. Otvos Jr., L.H. Younkin, N. Suzuki, S.G. Younkin, Amyloid beta protein (Ab) in Alzheimer's disease brain: biochemical and immunocytochemical analysis with antibodies specific for forms ending at Ab40 or Ab42(43), J. Biol. Chem. 270 (1995) 7013-7016.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7013-7016
    • Gravina, S.A.1    Ho, L.2    Eckman, C.B.3    Long, K.E.4    Otvos Jr., L.5    Younkin, L.H.6    Suzuki, N.7    Younkin, S.G.8
  • 20
    • 57149145222 scopus 로고    scopus 로고
    • The ratio of monomeric to aggregated forms of ab40 and ab42 is an important determinant of amyloidbeta aggregation, fibrillogenesis, and toxicity
    • A. Jan, O. Gokce, R. Luthi-Carter, H.A. Lashuel, The ratio of monomeric to aggregated forms of Ab40 and Ab42 is an important determinant of amyloidbeta aggregation, fibrillogenesis, and toxicity, J. Biol. Chem. 283 (2008) 28176-28189.
    • (2008) J. Biol. Chem. , vol.283 , pp. 28176-28189
    • Jan, A.1    Gokce, O.R.2    Lashuel, H.A.3
  • 21
    • 33745920161 scopus 로고    scopus 로고
    • Human amyloid- synthesis and clearance rates as measured in cerebrospinal fluid in vivo
    • DOI 10.1038/nm1438, PII NM1438
    • R.J. Bateman, L.Y. Munsell, J.C. Morris, R. Swarm, K.E. Yarasheski, D.M. Holtzman, Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo, Nat. Med. 12 (2006) 856-861. (Pubitemid 44050079)
    • (2006) Nature Medicine , vol.12 , Issue.7 , pp. 856-861
    • Bateman, R.J.1    Munsell, L.Y.2    Morris, J.C.3    Swarm, R.4    Yarasheski, K.E.5    Holtzman, D.M.6
  • 25
    • 80054084612 scopus 로고    scopus 로고
    • Quantitation of amyloid beta peptides ab(1-38), ab(1-40), and ab(1-42) in human cerebrospinal fluid by ultraperformance liquid chromatography-Tandem mass spectrometry
    • M.E. Lame, E.E. Chambers, M. Blatnik, Quantitation of amyloid beta peptides Ab(1-38), Ab(1-40), and Ab(1-42) in human cerebrospinal fluid by ultraperformance liquid chromatography-Tandem mass spectrometry, Anal. Biochem. 419 (2011) 133-139.
    • (2011) Anal. Biochem. , vol.419 , pp. 133-139
    • Lame, M.E.1    Chambers, E.E.2    Blatnik, M.3
  • 27
    • 42949113985 scopus 로고    scopus 로고
    • Straightforward ladder sequencing of peptides using a Lys-N metalloendopeptidase
    • DOI 10.1038/nmeth.1204, PII NMETH.1204
    • N. Taouatas, M.M. Drugan, A.J. Heck, S. Mohammed, Straightforward ladder sequencing of peptides using a Lys-N metalloendopeptidase, Nat. Methods 5 (2008) 405-407. (Pubitemid 351619098)
    • (2008) Nature Methods , vol.5 , Issue.5 , pp. 405-407
    • Taouatas, N.1    Drugan, M.M.2    Heck, A.J.R.3    Mohammed, S.4
  • 28
    • 33947507128 scopus 로고    scopus 로고
    • Fluctuations of CSF amyloid- levels: Implications for a diagnostic and therapeutic biomarker
    • DOI 10.1212/01.wnl.0000256043.50901.e3, PII 0000611420070227000011
    • R.J. Bateman, G. Wen, J.C. Morris, D.M. Holtzman, Fluctuations of CSF amyloidbeta levels: implications for a diagnostic and therapeutic biomarker, Neurology 68 (2007) 666-669. (Pubitemid 46667813)
    • (2007) Neurology , vol.68 , Issue.9 , pp. 666-669
    • Bateman, R.J.1    Wen, G.2    Morris, J.C.3    Holtzman, D.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.