Crystal structure of signal regulatory protein gamma (SIRPγ) in complex with an antibody Fab fragment

BMC Structural Biology

Volumn 13, Issue 1, 2013, Pages

  Nettleship, Joanne E ^a,b   Ren, Jingshan ^a   Scott, David J ^c,d   Rahman, Nahid ^a,b   Hatherley, Deborah ^e   Zhao, Yuguang ^a   Stuart, David I ^a,f   Barclay, A Neil ^e   Owens, Raymond J ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b RUTHERFORD APPLETON LABORATORY   (United Kingdom)

^c RUTHERFORD APPLETON LABORATORY   (United Kingdom)

^d UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f DIAMOND LIGHT SOURCE LTD   (United Kingdom)

Author keywords

Antigen binding complex; Receptor structure; Signal regulatory protein

Indexed keywords

IMMUNOGLOBULIN F(AB) FRAGMENT; INTEGRIN; MONOMER; REGULATOR PROTEIN; SIGNAL REGULATORY PROTEIN GAMMA; UNCLASSIFIED DRUG; ANTIGEN ANTIBODY COMPLEX; CELL SURFACE RECEPTOR; DIFFERENTIATION ANTIGEN; IMMUNOGLOBULIN RECEPTOR; RECOMBINANT PROTEIN; SIRPA PROTEIN, HUMAN; SIRPB1 PROTEIN, HUMAN; SIRPG PROTEIN, HUMAN;

ANTIGEN PRESENTING CELL; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLIZATION; HYDROGEN BOND; LYMPHOCYTE; PROTEIN ANALYSIS; PROTEIN STRUCTURE; SEDIMENTATION; SEDIMENTATION RATE; T LYMPHOCYTE; ULTRACENTRIFUGATION; ANTIGEN ANTIBODY COMPLEX; BIOSYNTHESIS; CHEMISTRY; DIMERIZATION; GENETICS; HEK293 CELL LINE; HUMAN; IMMUNOLOGY; METABOLISM; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ANTIGEN-ANTIBODY COMPLEX; ANTIGENS, DIFFERENTIATION; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; HEK293 CELLS; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; RECOMBINANT PROTEINS; ULTRACENTRIFUGATION;

EID: 84879814551     PISSN: None     EISSN: 14726807     Source Type: Journal    
DOI: 10.1186/1472-6807-13-13     Document Type: Article

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