Adhesion of human T cells to antigen-presenting cells through SIRPβ2-CD47 interaction costimulates T-cell proliferation

Blood

Volumn 105, Issue 6, 2005, Pages 2421-2427

  Piccio, Laura ^a   Vermi, William ^a   Boles, Kent S ^a   Fuchs, Anja ^a   Strader, Carey A ^a   Facchetti, Fabio ^a   Cella, Marina ^a   Colonna, Marco ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD47 ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN; KILLER CELL ACTIVATING RECEPTOR ASSOCIATED PROTEIN; PROTEIN TYROSINE PHOSPHATASE SHP 2; REGULATOR PROTEIN; SIGNAL REGULATORY PROTEIN BETA2; UNCLASSIFIED DRUG;

ANTIGEN PRESENTING CELL; ARTICLE; CELL ADHESION; CONTROLLED STUDY; GRANULOCYTE; HELPER CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LEUKEMIA CELL LINE; LYMPHOCYTE PROLIFERATION; MONOCYTE; NATURAL KILLER CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SUPPRESSOR CELL; T LYMPHOCYTE ACTIVATION; THYMOCYTE;

EID: 15244347763     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2004-07-2823     Document Type: Article

References (39)

1. Kharitonenkov A, Chen Z, Sures I, Wang H, Schilling J, Ullrich A. A family of proteins that inhibit signaling through tyrosine kinase receptors. Nature. 1997;386:181-186.
2. Cant CA, Ullrich A. Signal regulation by family conspiracy. Cell Mol Life Sci. 2001;58:117-124.
3. Barclay AN, Wright GJ, Brooke G, Brown MH. CD200 and membrane protein interactions in the control of myeloid cells. Trends Immunol. 2002;23:285-290.
4. Jiang P, Lagenaur CF, Narayanan V. Integrin-associated protein is a ligand for the P84 neural adhesion molecule. J Biol Chem. 1999;274:559-562.
5. Vemon-Wilson EF, Kee WJ, Willis AC, Barclay AN, Simmons DL, Brown MH. CD47 is a ligand for rat macrophage membrane signal regulatory protein SIRP (OX41) and human SIRPalpha 1. Eur J Immunol. 2000;30:2130-2137.
6. Seiffert M, Cant C, Chen Z, et al. Human signal-regulatory protein is expressed on normal, but not on subsets of leukemic myeloid cells and mediates cellular adhesion involving its counterreceptor CD47. Blood. 1999;94:3633-3643.
7. Seiffert M, Brossart P, Cant C, et al. Signal-regulatory protein alpha (SIRPalpha) but not SIRP-beta is involved in T-cell activation, binds to CD47 with high affinity, and is expressed on immature CD34(+)CD38(-) hematopoietic cells. Blood. 2001;97:2741-2749.
8. Brown E. Integrin-associated protein (CD47): an unusual activator of G protein signaling. J Clin Invest. 2001;107:1499-1500.
9. Brown EJ, Frazier WA. Integrin-associated protein (CD47) and its ligands. Trends Cell Biol. 2001;11:130-135.
10. Kim SO, Jiang J, Yi W, Feng GS, Frank SJ. Involvement of the Src homology 2-containing tyrosine phosphatase SHP-2 in growth hormone signaling. J Biol Chem. 1998;273:2344-2354.
11. Timms JF, Carlberg K, Gu H, et al. Identification of major binding proteins and substrates for the SH2-containing protein tyrosine phosphatase SHP-1 in macrophages. Mol Cell Biol. 1998;18: 3838-3850.
12. Veillette A, Thibaudeau E, Latour S. High expression of inhibitory receptor SHPS-1 and its association with protein-tyrosine phosphatase SHP-1 in macrophages. J Biol Chem. 1998;273:22719-22728.
13. Oldenburg PA, Zheleznyak A, Fang YF, Lagenaur CF, Gresham HD, Lindberg FP. Role of CD47 as a marker of self on red blood cells. Science. 2000;288:2051-2054.
14. Oldenborg PA, Gresham HD, Lindberg FP. CD47-signal regulatory protein alpha (SIRPalpha) regulates Fcgamma and complements receptor-mediated phagocytosis. J Exp Med. 2001;193: 855-862.
15. Latour S, Tanaka H, Demeure C, et al. Bidirectional negative regulation of human T and dendritic cells by CD47 and its cognate receptor signal-regulator protein-alpha: down-regulation of IL-12 responsiveness and inhibition of dendritic cell activation. J Immunol. 2001;167:2547-2554.
16. Fujioka Y, Matozaki T, Noguchi T, et al. A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion. Mol Cell Biol. 1996;16:6887-6899.
17. Cornu S, Weng W, Olinsky S, et al The murine P84 neural adhesion molecule is SHPS-1, a member of the phosphatase-binding protein family. J Neurosci. 1997;17:8702-8710.
18. Sano S, Ohnishi H, Omori A, Hasegawa J, Kubota M. BIT, an immune antigen receptor-like molecule in the brain. FEBS Lett. 1997;411:327-334.
19. Saginario C, Sterling H, Beckers C, et al. MFR, a putative receptor mediating the fusion of macrophages. Mol Cell Biol. 1998;18:6213-6223.
20. Fukunaga A, Nagai H, Noguchi T, et al SRC homology 2 domain-containing protein tyrosine phosphatase substrate 1 regulates the migration of Langerhans cells from the epidermis to draining lymph nodes. J Immunol. 2004;172:4091-4099.
21. de Vries HE, Hendriks JJ, Honing H, et al. Signal-regulatory protein alpha-CD47 interactions are required for the transmigration of monocytes across cerebral endothelium. J Immunol. 2002; 168:5832-5839.
22. Liu Y, Buhring HJ, Zen K, et al. Signal regulatory protein (SIRPalpha), a cellular ligand for CD47, regulates neutrophil transmigration. J Biol Chem. 2002;277:10028-10036.
23. Dietrich J, Cella M, Seiffert M, Buhring HJ, Colonna M. Cutting edge: signal-regulatory protein beta 1 is a DAP12-associated activating receptor expressed in myeloid cells. J Immunol. 2000;164: 9-12.
24. Tomasello E, Cant C, Buhring HJ, et al. Association of signal-regulatory proteins beta with KARAP/DAP-12. Eur J Immunol. 2000;30:2147-2156.
25. Lanier LL, Bakker AB. The ITAM-bearing trans-membrane adaptor DAP12 in lymphoid and myeloid cell function. Immunol Today. 2000;21:611-614.
26. Tomasello E, Blery M, Vely F, Vivier E. Signaling pathways engaged by NK cell receptors: double concerto for activating receptors, inhibitory receptors and NK cells. Semin Immunol. 2000;12:139-147.
27. Ichigotani Y, Matsuda S, Machida K, et al Molecular cloning of a novel human gene (SIRP-B2) which encodes a new member of the SIRP/ SHPS-1 protein family. J Hum Genet. 2000;45: 378-382.
28. Reinhold MI, Green JM, Lindberg FP, Ticchioni M, Brown EJ. Cell spreading distinguishes the mechanism of augmentation of T cell activation by integrin-associated protein/CD47 and CD28. Int Immunol. 1999;11:707-718.
29. NosakaT, KawashimaT, Misawa K, Ikuta K, Mui AL, Kitamura T. STATS as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells. EMBO J. 1999;18:4754-4765.
30. Ettinger R, Browning JL, Michie SA, van Ewijk W, McDevitt HO. Disrupted splenic architecture, but normal lymph node development in mice expressing a soluble lymphotoxin-beta receptor-IgG1 fusion protein. Proc Natl Acad Sci U S A. 1996;93:13102-13107.
31. Lanzavecchia A, Sallusto F. Progressive differentiation and selection of the fittest in the immune response. Nat Rev Immunol. 2002;2:982-987.
32. Purbhoo MA, Irvine DJ, Huppa JB, Davis MM. T cell killing does not require the formation of a stable mature immunological synapse. Nat Immunol. 2004;5:524-530.
33. Dustin ML, Allen PM, Shaw AS. Environmental control of immunological synapse formation and duration. Trends Immunol. 2001;22:192-194.
34. Ticchioni M, Deckert M, Maty F, Bernard G, Brown EJ, Bernard A. Integrin-associated protein (CD47) is a comitogenic molecule on CD3-activated human T cells. J Immunol. 1997;158:677-684.
35. Reinhold MI, Lindberg FP, Kersh GJ, Allen PM, Brawn EJ. Costimulation of T cell activation by integrin-associated protein (CD47) is an adhesion-dependent, CD28-independent signaling pathway. J Exp Med. 1997;185:1-11.
36. Trowsdale J. Genetic and functional relationships between MHC and NK receptor genes. Immunity. 2001;15:363-374.
37. Arase H, Lanier LL. Virus-driven evolution of natural killer cell receptors. Microbes Infect. 2002;4:1505-1512.
38. Parkinson JE, Sanderson CM, Smith GL. The vaccinia virus A38L gene product is a 33-kDa integral membrane glycoprotein. Virology. 1995;214:177-188.
39. National Library of Medicine, National Center for Biotechnology Information. The Reference Sequence (RefSeq) Project. In: The NCBI handbook [internet]. 2002. Available at: http://www.ncbi.nlm. nih.gov/entrez/query.fcgi? db=Books. Accessed August 21, 2004.