Towards Clinical Molecular Diagnosis of Inherited Cardiac Conditions: A Comparison of Bench-Top Genome DNA Sequencers

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Li, Xinzhong ^a   Buckton, Andrew J ^b   Wilkinson, Samuel L ^b   John, Shibu ^a   Walsh, Roddy ^b   Novotny, Tomas ^c   Valaskova, Iveta ^c   Gupta, Manu ^b   Game, Laurence ^d   Barton, Paul J R ^a,b   Cook, Stuart A ^a,e   Ware, James S ^a,b  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b ROYAL BROMPTON AND HAREFIELD NHS FOUNDATION TRUST   (United Kingdom)

^c UNIVERSITY HOSPITAL BRNO   (Czech Republic)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e DEPARTMENT OF CARDIOLOGY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA;

ANALYTICAL EQUIPMENT; ARTICLE; CLINICAL ASSESSMENT; CONTROLLED STUDY; COST CONTROL; DIAGNOSTIC ACCURACY; DIAGNOSTIC KIT; DIAGNOSTIC TEST ACCURACY STUDY; DNA BASE COMPOSITION; DNA SEQUENCE; EXON; GENETIC ASSOCIATION; GENETIC VARIABILITY; HEALTH CARE COST; HEART ARRHYTHMIA; HUMAN; INTERMETHOD COMPARISON; MICROFLUIDIC ANALYSIS; MOLECULAR DIAGNOSIS; MULTIPLEX POLYMERASE CHAIN REACTION; NEXT GENERATION SEQUENCING; PREDICTIVE VALUE; QUALITY CONTROL; SENSITIVITY AND SPECIFICITY;

ARRHYTHMIAS, CARDIAC; EXONS; GENETIC TESTING; GENOME, HUMAN; HEREDITY; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MOLECULAR DIAGNOSTIC TECHNIQUES; SEQUENCE ANALYSIS, DNA;

EID: 84879813568     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0067744     Document Type: Article

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