메뉴 건너뛰기




Volumn 12, Issue 1, 2013, Pages

Caffeic acid phenethyl amide improves glucose homeostasis and attenuates the progression of vascular dysfunction in Streptozotocin-induced diabetic rats

Author keywords

Caffeic acid phenethyl amide; Diabetes; Vascular dysfunction

Indexed keywords

ANTIDIABETIC AGENT; CAFFEIC ACID DERIVATIVE; CAFFEIC ACID PHENETHYL AMIDE; GLUCOSE; INSULIN; NITRIC OXIDE SYNTHASE INHIBITOR; PHENYLEPHRINE; UNCLASSIFIED DRUG; GLUCOSE BLOOD LEVEL; PHENETHYL ALCOHOL; STREPTOZOCIN;

EID: 84879812091     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/1475-2840-12-99     Document Type: Article
Times cited : (21)

References (53)
  • 1
    • 84855161991 scopus 로고    scopus 로고
    • Diagnosis and classification of diabetes mellitus
    • 3632174, 22187472, American Diabetes Association
    • American Diabetes Association Diagnosis and classification of diabetes mellitus. Diabetes Care 2012, 35(Suppl 1):S64-71. 3632174, 22187472, American Diabetes Association.
    • (2012) Diabetes Care , vol.35 , Issue.SUPPL. 1
  • 2
    • 42349087252 scopus 로고    scopus 로고
    • Microvascular and macrovascular complications of diabetes
    • Fowler MJ. Microvascular and macrovascular complications of diabetes. Clinical Diabetes 2008, 26:77-82.
    • (2008) Clinical Diabetes , vol.26 , pp. 77-82
    • Fowler, M.J.1
  • 3
    • 23644439784 scopus 로고    scopus 로고
    • Vascular complications in diabetes mellitus: the role of endothelial dysfunction
    • Schalkwijk CG, Stehouwer CD. Vascular complications in diabetes mellitus: the role of endothelial dysfunction. Clin Sci (Lond) 2005, 109:143-159.
    • (2005) Clin Sci (Lond) , vol.109 , pp. 143-159
    • Schalkwijk, C.G.1    Stehouwer, C.D.2
  • 4
    • 26244468294 scopus 로고    scopus 로고
    • Cardiovascular autonomic neuropathy due to diabetes mellitus: clinical manifestations, consequences, and treatment
    • 10.1210/jc.2005-0754, 16014401
    • Maser RE, Lenhard MJ. Cardiovascular autonomic neuropathy due to diabetes mellitus: clinical manifestations, consequences, and treatment. J Clin Endocrinol Metab 2005, 90:5896-5903. 10.1210/jc.2005-0754, 16014401.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 5896-5903
    • Maser, R.E.1    Lenhard, M.J.2
  • 5
    • 33747114039 scopus 로고    scopus 로고
    • Preventing cardiovascular disease and diabetes: a call to action from the american diabetes association and the american heart association
    • 10.1161/CIRCULATIONAHA.106.176583, 16801475
    • Eckel RH, Kahn R, Robertson RM, Rizza RA. Preventing cardiovascular disease and diabetes: a call to action from the american diabetes association and the american heart association. Circulation 2006, 113:2943-2946. 10.1161/CIRCULATIONAHA.106.176583, 16801475.
    • (2006) Circulation , vol.113 , pp. 2943-2946
    • Eckel, R.H.1    Kahn, R.2    Robertson, R.M.3    Rizza, R.A.4
  • 7
    • 34547687780 scopus 로고    scopus 로고
    • The effect of intensive diabetes treatment on resting heart rate in type 1 diabetes: the diabetes control and complications trial/epidemiology of diabetes interventions and complications study
    • 10.2337/dc06-1441, 2654598, 17468351
    • Paterson AD, Rutledge BN, Cleary PA, Lachin JM, Crow RS. The effect of intensive diabetes treatment on resting heart rate in type 1 diabetes: the diabetes control and complications trial/epidemiology of diabetes interventions and complications study. Diabetes Care 2007, 30:2107-2112. 10.2337/dc06-1441, 2654598, 17468351.
    • (2007) Diabetes Care , vol.30 , pp. 2107-2112
    • Paterson, A.D.1    Rutledge, B.N.2    Cleary, P.A.3    Lachin, J.M.4    Crow, R.S.5
  • 8
    • 84855898684 scopus 로고    scopus 로고
    • Acute and chronic animal models for the evaluation of anti-diabetic agents
    • 10.1186/1475-2840-11-9, 3286385, 22257465
    • Kumar S, Singh R, Vasudeva N, Sharma S. Acute and chronic animal models for the evaluation of anti-diabetic agents. Cardiovasc Diabetol 2012, 11:9. 10.1186/1475-2840-11-9, 3286385, 22257465.
    • (2012) Cardiovasc Diabetol , vol.11 , pp. 9
    • Kumar, S.1    Singh, R.2    Vasudeva, N.3    Sharma, S.4
  • 9
    • 34548858217 scopus 로고    scopus 로고
    • Simvastatin protects against multiple low-dose streptozotocin-induced type 1 diabetes in CD-1 mice and recurrence of disease in nonobese diabetic mice
    • 10.1124/jpet.107.122655, 17636011
    • Rydgren T, Vaarala O, Sandler S. Simvastatin protects against multiple low-dose streptozotocin-induced type 1 diabetes in CD-1 mice and recurrence of disease in nonobese diabetic mice. J Pharmacol Exp Ther 2007, 323:180-185. 10.1124/jpet.107.122655, 17636011.
    • (2007) J Pharmacol Exp Ther , vol.323 , pp. 180-185
    • Rydgren, T.1    Vaarala, O.2    Sandler, S.3
  • 10
    • 84864917869 scopus 로고    scopus 로고
    • Caffeic acid phenylethyl amide protects against the metabolic consequences in diabetes mellitus induced by diet and streptozocin
    • 3388606, 22778782
    • Weng YC, Chuang ST, Lin YC, Chuang CF, Chi TC, Chiu HL, Kuo YH, Su MJ. Caffeic acid phenylethyl amide protects against the metabolic consequences in diabetes mellitus induced by diet and streptozocin. Evid Based Complement Alternat Med 2012, 2012:984780. 3388606, 22778782.
    • (2012) Evid Based Complement Alternat Med , vol.2012 , pp. 984780
    • Weng, Y.C.1    Chuang, S.T.2    Lin, Y.C.3    Chuang, C.F.4    Chi, T.C.5    Chiu, H.L.6    Kuo, Y.H.7    Su, M.J.8
  • 11
    • 84879081433 scopus 로고    scopus 로고
    • Increase in cardiac M2-muscarinic receptor expression is regulated by GATA binding protein 4 (GATA-4) in streptozotocin-induced diabetic rats
    • 10.1016/j.ijcard.2012.01.015, 22293779
    • Mar GYKP, Chen LJ, Cheng KC, Li YX, Cheng JT. Increase in cardiac M2-muscarinic receptor expression is regulated by GATA binding protein 4 (GATA-4) in streptozotocin-induced diabetic rats. Int J Cardiol 2013, 167:436-441. 10.1016/j.ijcard.2012.01.015, 22293779.
    • (2013) Int J Cardiol , vol.167 , pp. 436-441
    • Mar, G.Y.K.P.1    Chen, L.J.2    Cheng, K.C.3    Li, Y.X.4    Cheng, J.T.5
  • 12
    • 84865424248 scopus 로고    scopus 로고
    • Mechanisms underlining gender differences in phenylephrine contraction of normoglycaemic and short-term streptozotocin-induced diabetic WKY rat aorta
    • 10.1016/j.vph.2011.11.009, 22172524
    • Aloysius UI, Achike FI, Mustafa MR. Mechanisms underlining gender differences in phenylephrine contraction of normoglycaemic and short-term streptozotocin-induced diabetic WKY rat aorta. Vascul Pharmacol 2012, 57:81-90. 10.1016/j.vph.2011.11.009, 22172524.
    • (2012) Vascul Pharmacol , vol.57 , pp. 81-90
    • Aloysius, U.I.1    Achike, F.I.2    Mustafa, M.R.3
  • 14
    • 81555237210 scopus 로고    scopus 로고
    • Nicorandil prevents endothelial dysfunction due to antioxidative effects via normalisation of NADPH oxidase and nitric oxide synthase in streptozotocin diabetic rats
    • 10.1186/1475-2840-10-105, 3248842, 22107602
    • Serizawa K, Yogo K, Aizawa K, Tashiro Y, Ishizuka N. Nicorandil prevents endothelial dysfunction due to antioxidative effects via normalisation of NADPH oxidase and nitric oxide synthase in streptozotocin diabetic rats. Cardiovasc Diabetol 2011, 10:105. 10.1186/1475-2840-10-105, 3248842, 22107602.
    • (2011) Cardiovasc Diabetol , vol.10 , pp. 105
    • Serizawa, K.1    Yogo, K.2    Aizawa, K.3    Tashiro, Y.4    Ishizuka, N.5
  • 15
    • 0026490369 scopus 로고
    • Endothelium-dependent increase in vascular sensitivity to phenylephrine in long-term streptozotocin diabetic rat aorta
    • 10.1111/j.1476-5381.1992.tb13395.x, 1907920, 1467844
    • Chang KS, Stevens WC. Endothelium-dependent increase in vascular sensitivity to phenylephrine in long-term streptozotocin diabetic rat aorta. Br J Pharmacol 1992, 107:983-990. 10.1111/j.1476-5381.1992.tb13395.x, 1907920, 1467844.
    • (1992) Br J Pharmacol , vol.107 , pp. 983-990
    • Chang, K.S.1    Stevens, W.C.2
  • 16
    • 75549087108 scopus 로고    scopus 로고
    • Insulin therapy for type 2 diabetes
    • 2811456, 19875560
    • Swinnen SG, Hoekstra JB, DeVries JH. Insulin therapy for type 2 diabetes. Diabetes Care 2009, 32(Suppl 2):S253-259. 2811456, 19875560.
    • (2009) Diabetes Care , vol.32 , Issue.SUPPL. 2
    • Swinnen, S.G.1    Hoekstra, J.B.2    DeVries, J.H.3
  • 17
    • 70349254891 scopus 로고    scopus 로고
    • Anti-inflammatory effects of caffeic acid phenethyl ester (CAPE), a nuclear factor-kappaB inhibitor, on helicobacter pylori-induced gastritis in mongolian gerbils
    • 10.1002/ijc.24586, 19610061
    • Toyoda T, Tsukamoto T, Takasu S, Shi L, Hirano N, Ban H, Kumagai T, Tatematsu M. Anti-inflammatory effects of caffeic acid phenethyl ester (CAPE), a nuclear factor-kappaB inhibitor, on helicobacter pylori-induced gastritis in mongolian gerbils. Int J Cancer 2009, 125:1786-1795. 10.1002/ijc.24586, 19610061.
    • (2009) Int J Cancer , vol.125 , pp. 1786-1795
    • Toyoda, T.1    Tsukamoto, T.2    Takasu, S.3    Shi, L.4    Hirano, N.5    Ban, H.6    Kumagai, T.7    Tatematsu, M.8
  • 18
    • 0028070994 scopus 로고
    • Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds
    • 10.1016/0006-2952(94)90291-7, 7520698
    • Fesen MR, Pommier Y, Leteurtre F, Hiroguchi S, Yung J, Kohn KW. Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds. Biochem Pharmacol 1994, 48:595-608. 10.1016/0006-2952(94)90291-7, 7520698.
    • (1994) Biochem Pharmacol , vol.48 , pp. 595-608
    • Fesen, M.R.1    Pommier, Y.2    Leteurtre, F.3    Hiroguchi, S.4    Yung, J.5    Kohn, K.W.6
  • 19
    • 41349086443 scopus 로고    scopus 로고
    • Caffeic acid phenethyl ester inhibits invasion and expression of matrix metalloproteinase in SK-Hep1 human hepatocellular carcinoma cells by targeting nuclear factor kappa B
    • 10.1007/s12263-007-0067-9, 2478489, 18850224
    • Lee KW, Kang NJ, Kim JH, Lee KM, Lee DE, Hur HJ, Lee HJ. Caffeic acid phenethyl ester inhibits invasion and expression of matrix metalloproteinase in SK-Hep1 human hepatocellular carcinoma cells by targeting nuclear factor kappa B. Genes Nutr 2008, 2:319-322. 10.1007/s12263-007-0067-9, 2478489, 18850224.
    • (2008) Genes Nutr , vol.2 , pp. 319-322
    • Lee, K.W.1    Kang, N.J.2    Kim, J.H.3    Lee, K.M.4    Lee, D.E.5    Hur, H.J.6    Lee, H.J.7
  • 21
    • 11844289636 scopus 로고    scopus 로고
    • Effects of caffeic acid phenethyl ester on lipid peroxidation and antioxidant enzymes in diabetic rat heart
    • 10.1016/j.clinbiochem.2004.10.003, 15642285
    • Okutan H, Ozcelik N, Yilmaz HR, Uz E. Effects of caffeic acid phenethyl ester on lipid peroxidation and antioxidant enzymes in diabetic rat heart. Clin Biochem 2005, 38:191-196. 10.1016/j.clinbiochem.2004.10.003, 15642285.
    • (2005) Clin Biochem , vol.38 , pp. 191-196
    • Okutan, H.1    Ozcelik, N.2    Yilmaz, H.R.3    Uz, E.4
  • 22
    • 0037462170 scopus 로고    scopus 로고
    • Vascular effects of caffeic acid phenethyl ester (CAPE) on isolated rat thoracic aorta
    • 10.1016/S0024-3205(03)00235-2, 12726888
    • Cicala C, Morello S, Iorio C, Capasso R, Borrelli F, Mascolo N. Vascular effects of caffeic acid phenethyl ester (CAPE) on isolated rat thoracic aorta. Life Sci 2003, 73:73-80. 10.1016/S0024-3205(03)00235-2, 12726888.
    • (2003) Life Sci , vol.73 , pp. 73-80
    • Cicala, C.1    Morello, S.2    Iorio, C.3    Capasso, R.4    Borrelli, F.5    Mascolo, N.6
  • 23
    • 13244259545 scopus 로고    scopus 로고
    • Oral flavonoid supplementation attenuates atherosclerosis development in apolipoprotein E-deficient mice
    • Hishikawa K, Nakaki T, Fujita T. Oral flavonoid supplementation attenuates atherosclerosis development in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 2005, 25:442-446.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 442-446
    • Hishikawa, K.1    Nakaki, T.2    Fujita, T.3
  • 24
    • 4644273972 scopus 로고    scopus 로고
    • The effects of the caffeic acid phenethyl ester (CAPE) on erythrocyte membrane damage after hind limb ischaemia-reperfusion
    • 10.1002/cbf.1102, 15338467
    • Tamer L, Sucu N, Ercan B, Unlu A, Calikoglu M, Bilgin R, Degirmenci U, Atik U. The effects of the caffeic acid phenethyl ester (CAPE) on erythrocyte membrane damage after hind limb ischaemia-reperfusion. Cell Biochem Funct 2004, 22:287-290. 10.1002/cbf.1102, 15338467.
    • (2004) Cell Biochem Funct , vol.22 , pp. 287-290
    • Tamer, L.1    Sucu, N.2    Ercan, B.3    Unlu, A.4    Calikoglu, M.5    Bilgin, R.6    Degirmenci, U.7    Atik, U.8
  • 25
    • 69249203820 scopus 로고    scopus 로고
    • Caffeic acid phenethyl ester (CAPE) exhibits significant potential as an antidiabetic and liver-protective agent in streptozotocin-induced diabetic rats
    • 10.1016/j.phrs.2009.03.017, 19717012
    • Celik S, Erdogan S, Tuzcu M. Caffeic acid phenethyl ester (CAPE) exhibits significant potential as an antidiabetic and liver-protective agent in streptozotocin-induced diabetic rats. Pharmacol Res 2009, 60:270-276. 10.1016/j.phrs.2009.03.017, 19717012.
    • (2009) Pharmacol Res , vol.60 , pp. 270-276
    • Celik, S.1    Erdogan, S.2    Tuzcu, M.3
  • 26
    • 0034011165 scopus 로고    scopus 로고
    • Caffeic acid as active principle from the fruit of xanthiumstrumarium to lower plasma glucose in diabetic rats
    • 10.1055/s-2000-8561, 10821047
    • Hsu FL, Chen YC, Cheng JT. Caffeic acid as active principle from the fruit of xanthiumstrumarium to lower plasma glucose in diabetic rats. Planta Med 2000, 66:228-230. 10.1055/s-2000-8561, 10821047.
    • (2000) Planta Med , vol.66 , pp. 228-230
    • Hsu, F.L.1    Chen, Y.C.2    Cheng, J.T.3
  • 27
    • 11144283078 scopus 로고    scopus 로고
    • Effects of propolis on blood glucose, blood lipid and free radicals in rats with diabetes mellitus
    • 10.1016/j.phrs.2004.06.011, 15629260
    • Fuliang HU, Hepburn HR, Xuan H, Chen M, Daya S, Radloff SE. Effects of propolis on blood glucose, blood lipid and free radicals in rats with diabetes mellitus. Pharmacol Res 2005, 51:147-152. 10.1016/j.phrs.2004.06.011, 15629260.
    • (2005) Pharmacol Res , vol.51 , pp. 147-152
    • Fuliang, H.U.1    Hepburn, H.R.2    Xuan, H.3    Chen, M.4    Daya, S.5    Radloff, S.E.6
  • 28
    • 22044456421 scopus 로고    scopus 로고
    • Strong antihyperglycemic effects of water-soluble fraction of brazilian propolis and its bioactive constituent, 3,4,5-tri-O-caffeoylquinic acid
    • 10.1248/bpb.27.1797, 15516726
    • Matsui T, Ebuchi S, Fujise T, Abesundara KJ, Doi S, Yamada H, Matsumoto K. Strong antihyperglycemic effects of water-soluble fraction of brazilian propolis and its bioactive constituent, 3,4,5-tri-O-caffeoylquinic acid. Biol Pharm Bull 2004, 27:1797-1803. 10.1248/bpb.27.1797, 15516726.
    • (2004) Biol Pharm Bull , vol.27 , pp. 1797-1803
    • Matsui, T.1    Ebuchi, S.2    Fujise, T.3    Abesundara, K.J.4    Doi, S.5    Yamada, H.6    Matsumoto, K.7
  • 29
    • 0842334472 scopus 로고    scopus 로고
    • Isolation and purification of the hypoglycaemic principle present in capsicum frutescens
    • 10.1002/ptr.1328, 14750210
    • Tolan I, Ragoobirsingh D, Morrison EY. Isolation and purification of the hypoglycaemic principle present in capsicum frutescens. Phytother Res 2004, 18:95-96. 10.1002/ptr.1328, 14750210.
    • (2004) Phytother Res , vol.18 , pp. 95-96
    • Tolan, I.1    Ragoobirsingh, D.2    Morrison, E.Y.3
  • 30
    • 14844362006 scopus 로고    scopus 로고
    • Photo-irradiated curcumin supplementation in streptozotocin-induced diabetic rats: effect on lipid peroxidation
    • 10.2515/therapie:2004110, 15789828
    • Mahesh T, Sri Balasubashini MM, Menon VP. Photo-irradiated curcumin supplementation in streptozotocin-induced diabetic rats: effect on lipid peroxidation. Therapie 2004, 59:639-644. 10.2515/therapie:2004110, 15789828.
    • (2004) Therapie , vol.59 , pp. 639-644
    • Mahesh, T.1    Sri Balasubashini, M.M.2    Menon, V.P.3
  • 31
    • 84859445787 scopus 로고    scopus 로고
    • Stability of caffeic acid phenethyl amide (CAPA) in rat plasma
    • 10.1002/bmc.1702, 21915890
    • Yang J, Kerwin SM, Bowman PD, Stavchansky S. Stability of caffeic acid phenethyl amide (CAPA) in rat plasma. Biomed Chromatogr 2012, 26:594-598. 10.1002/bmc.1702, 21915890.
    • (2012) Biomed Chromatogr , vol.26 , pp. 594-598
    • Yang, J.1    Kerwin, S.M.2    Bowman, P.D.3    Stavchansky, S.4
  • 32
    • 77955315014 scopus 로고    scopus 로고
    • Synthesis of a series of caffeic acid phenethyl amide (CAPA) fluorinated derivatives: comparison of cytoprotective effects to caffeic acid phenethyl ester (CAPE)
    • 10.1016/j.bmc.2010.05.080, 20598894
    • Yang J, Marriner GA, Wang X, Bowman PD, Kerwin SM, Stavchansky S. Synthesis of a series of caffeic acid phenethyl amide (CAPA) fluorinated derivatives: comparison of cytoprotective effects to caffeic acid phenethyl ester (CAPE). Bioorg Med Chem 2010, 18:5032-5038. 10.1016/j.bmc.2010.05.080, 20598894.
    • (2010) Bioorg Med Chem , vol.18 , pp. 5032-5038
    • Yang, J.1    Marriner, G.A.2    Wang, X.3    Bowman, P.D.4    Kerwin, S.M.5    Stavchansky, S.6
  • 33
    • 0001201369 scopus 로고    scopus 로고
    • Isolation and activity of N-p-coumaroyltyramine, an α-glucosidase inhibitor in welsh onion (allium fistulosum)
    • Nishioka TW, Kawabata J, Niki J, Niki R. Isolation and activity of N-p-coumaroyltyramine, an α-glucosidase inhibitor in welsh onion (allium fistulosum). Biosci Biotechnol Biochem 1997, 61:4.
    • (1997) Biosci Biotechnol Biochem , vol.61 , pp. 4
    • Nishioka, T.W.1    Kawabata, J.2    Niki, J.3    Niki, R.4
  • 34
    • 38349075791 scopus 로고    scopus 로고
    • Induction of adiponectin by natural and synthetic phenolamides in mouse and human preadipocytes and its enhancement by docosahexaenoic acid
    • 10.1016/j.lfs.2007.11.016, 18166202
    • Yamazaki Y, Kawano Y, Uebayasi M. Induction of adiponectin by natural and synthetic phenolamides in mouse and human preadipocytes and its enhancement by docosahexaenoic acid. Life Sci 2008, 82:290-300. 10.1016/j.lfs.2007.11.016, 18166202.
    • (2008) Life Sci , vol.82 , pp. 290-300
    • Yamazaki, Y.1    Kawano, Y.2    Uebayasi, M.3
  • 35
    • 77956628959 scopus 로고    scopus 로고
    • Antihyperglycemic effect of a caffeamide derivative, KS370G, in normal and diabetic mice
    • 10.1021/jf1024246, 20804127
    • Weng YC, Chiu HL, Lin YC, Chi TC, Kuo YH, Su MJ. Antihyperglycemic effect of a caffeamide derivative, KS370G, in normal and diabetic mice. J Agric Food Chem 2010, 58:10033-10038. 10.1021/jf1024246, 20804127.
    • (2010) J Agric Food Chem , vol.58 , pp. 10033-10038
    • Weng, Y.C.1    Chiu, H.L.2    Lin, Y.C.3    Chi, T.C.4    Kuo, Y.H.5    Su, M.J.6
  • 36
    • 84860836670 scopus 로고    scopus 로고
    • KS370G, A synthetic caffeamide derivative, improves left ventricular hypertrophy and function in pressure-overload mice heart
    • 10.1016/j.ejphar.2012.03.029, 22484506
    • Weng YC, Chuang CF, Chuang ST, Chiu HL, Kuo YH, Su MJ. KS370G, A synthetic caffeamide derivative, improves left ventricular hypertrophy and function in pressure-overload mice heart. Eur J Pharmacol 2012, 684:108-115. 10.1016/j.ejphar.2012.03.029, 22484506.
    • (2012) Eur J Pharmacol , vol.684 , pp. 108-115
    • Weng, Y.C.1    Chuang, C.F.2    Chuang, S.T.3    Chiu, H.L.4    Kuo, Y.H.5    Su, M.J.6
  • 37
    • 34147127033 scopus 로고    scopus 로고
    • Serotonin enhances beta-endorphin secretion to lower plasma glucose in streptozotocin-induced diabetic rats
    • 10.1016/j.lfs.2007.02.016, 17397876
    • Chi TC, Ho YJ, Chen WP, Chi TL, Lee SS, Cheng JT, Su MJ. Serotonin enhances beta-endorphin secretion to lower plasma glucose in streptozotocin-induced diabetic rats. Life Sci 2007, 80:1832-1838. 10.1016/j.lfs.2007.02.016, 17397876.
    • (2007) Life Sci , vol.80 , pp. 1832-1838
    • Chi, T.C.1    Ho, Y.J.2    Chen, W.P.3    Chi, T.L.4    Lee, S.S.5    Cheng, J.T.6    Su, M.J.7
  • 38
    • 79959478932 scopus 로고    scopus 로고
    • Molecular role of GATA binding protein 4 (GATA-4) in hyperglycemia-induced reduction of cardiac contractility
    • 10.1186/1475-2840-10-57, 3141394, 21702924
    • Ku PM, Chen LJ, Liang JR, Cheng KC, Li YX, Cheng JT. Molecular role of GATA binding protein 4 (GATA-4) in hyperglycemia-induced reduction of cardiac contractility. Cardiovasc Diabetol 2011, 10:57. 10.1186/1475-2840-10-57, 3141394, 21702924.
    • (2011) Cardiovasc Diabetol , vol.10 , pp. 57
    • Ku, P.M.1    Chen, L.J.2    Liang, J.R.3    Cheng, K.C.4    Li, Y.X.5    Cheng, J.T.6
  • 39
    • 0026323311 scopus 로고
    • Beneficial effects of dietary acarbose in the streptozotocin-induced diabetic rat
    • 10.1016/0026-0495(91)90028-U, 1961120
    • Katovich MJ, Meldrum MJ, Vasselli JR. Beneficial effects of dietary acarbose in the streptozotocin-induced diabetic rat. Metabolism 1991, 40:1275-1282. 10.1016/0026-0495(91)90028-U, 1961120.
    • (1991) Metabolism , vol.40 , pp. 1275-1282
    • Katovich, M.J.1    Meldrum, M.J.2    Vasselli, J.R.3
  • 40
    • 0028246938 scopus 로고
    • Increased plasma glucose levels after hypnorm anaesthesia, but not after pentobarbital anaesthesia in rats
    • 10.1258/002367794780681723, 7967463
    • Johansen O, Vaaler S, Jorde R, Reikeras O. Increased plasma glucose levels after hypnorm anaesthesia, but not after pentobarbital anaesthesia in rats. Lab Anim 1994, 28:244-248. 10.1258/002367794780681723, 7967463.
    • (1994) Lab Anim , vol.28 , pp. 244-248
    • Johansen, O.1    Vaaler, S.2    Jorde, R.3    Reikeras, O.4
  • 41
    • 33947321153 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-kinase is involved in the antihyperglycemic effect induced by resveratrol in streptozotocin-induced diabetic rats
    • 10.1016/j.lfs.2007.02.002, 17346750
    • Chi TC, Chen WP, Chi TL, Kuo TF, Lee SS, Cheng JT, Su MJ. Phosphatidylinositol-3-kinase is involved in the antihyperglycemic effect induced by resveratrol in streptozotocin-induced diabetic rats. Life Sci 2007, 80:1713-1720. 10.1016/j.lfs.2007.02.002, 17346750.
    • (2007) Life Sci , vol.80 , pp. 1713-1720
    • Chi, T.C.1    Chen, W.P.2    Chi, T.L.3    Kuo, T.F.4    Lee, S.S.5    Cheng, J.T.6    Su, M.J.7
  • 43
    • 33751061976 scopus 로고    scopus 로고
    • Antihyperglycemic effect of aporphines and their derivatives in normal and diabetic rats
    • 10.1055/s-2006-947199, 16924583
    • Chi TC, Lee SS, Su MJ. Antihyperglycemic effect of aporphines and their derivatives in normal and diabetic rats. Planta Med 2006, 72:1175-1180. 10.1055/s-2006-947199, 16924583.
    • (2006) Planta Med , vol.72 , pp. 1175-1180
    • Chi, T.C.1    Lee, S.S.2    Su, M.J.3
  • 44
    • 0024589061 scopus 로고
    • Ischemia-induced and reperfusion-induced arrhythmias: importance of heart rate
    • Bernier M, Curtis MJ, Hearse DJ. Ischemia-induced and reperfusion-induced arrhythmias: importance of heart rate. Am J Physiol 1989, 256:H21-31.
    • (1989) Am J Physiol , vol.256
    • Bernier, M.1    Curtis, M.J.2    Hearse, D.J.3
  • 45
    • 44949212700 scopus 로고    scopus 로고
    • Comparison of the cardiac electrophysiological effects between doxazosin and bunazosin
    • 10.1007/s11373-008-9249-8, 18427952
    • Lee AS, Chen WP, Su MJ. Comparison of the cardiac electrophysiological effects between doxazosin and bunazosin. J Biomed Sci 2008, 15:519-528. 10.1007/s11373-008-9249-8, 18427952.
    • (2008) J Biomed Sci , vol.15 , pp. 519-528
    • Lee, A.S.1    Chen, W.P.2    Su, M.J.3
  • 46
    • 84878439301 scopus 로고    scopus 로고
    • P2X7 Receptor activation contributes to an initial upstream mechanism of lipopolysaccharide-induced vascular dysfunction
    • Chiao CW, da Silva-Santos JE, Giachini FR, Tostes RC, Su MJ, Webb RC. P2X7 Receptor activation contributes to an initial upstream mechanism of lipopolysaccharide-induced vascular dysfunction. Clin Sci (Lond) 2013, 125:131-141.
    • (2013) Clin Sci (Lond) , vol.125 , pp. 131-141
    • Chiao, C.W.1    da Silva-Santos, J.E.2    Giachini, F.R.3    Tostes, R.C.4    Su, M.J.5    Webb, R.C.6
  • 47
    • 0034997704 scopus 로고    scopus 로고
    • Aprotinin impairs endothelium-dependent relaxation in rat aorta and inhibits nitric oxide release from rat coronary endothelial cells
    • 10.1016/S0008-6363(01)00268-1, 11376635
    • Ulker S, Cinar MG, Bayraktutan U, Evinc A. Aprotinin impairs endothelium-dependent relaxation in rat aorta and inhibits nitric oxide release from rat coronary endothelial cells. Cardiovasc Res 2001, 50:589-596. 10.1016/S0008-6363(01)00268-1, 11376635.
    • (2001) Cardiovasc Res , vol.50 , pp. 589-596
    • Ulker, S.1    Cinar, M.G.2    Bayraktutan, U.3    Evinc, A.4
  • 49
    • 0043092399 scopus 로고    scopus 로고
    • The streptozotocin-diabetic rat as a model of the chronic complications of human diabetes
    • 10.1046/j.1444-2892.2003.00160.x, 16352106
    • Wei M, Ong L, Smith MT, Ross FB, Schmid K, Hoey AJ, Burstow D, Brown L. The streptozotocin-diabetic rat as a model of the chronic complications of human diabetes. Heart Lung Circ 2003, 12:44-50. 10.1046/j.1444-2892.2003.00160.x, 16352106.
    • (2003) Heart Lung Circ , vol.12 , pp. 44-50
    • Wei, M.1    Ong, L.2    Smith, M.T.3    Ross, F.B.4    Schmid, K.5    Hoey, A.J.6    Burstow, D.7    Brown, L.8
  • 51
    • 33748438730 scopus 로고    scopus 로고
    • Incretin mimetics and dipeptidyl peptidase-IV inhibitors: a review of emerging therapies for type 2 diabetes
    • 10.1089/dia.2006.8.385, 16800760
    • Kendall DM, Kim D, Maggs D. Incretin mimetics and dipeptidyl peptidase-IV inhibitors: a review of emerging therapies for type 2 diabetes. Diabetes Technol Ther 2006, 8:385-396. 10.1089/dia.2006.8.385, 16800760.
    • (2006) Diabetes Technol Ther , vol.8 , pp. 385-396
    • Kendall, D.M.1    Kim, D.2    Maggs, D.3
  • 52
    • 0020519768 scopus 로고
    • Effect of alpha-1-blockade by prazosin on blood sugar, insulin and glucagon levels in normals and non-insulin dependent diabetics
    • Ferlito S, Puleo F, Carra G, Damante G, Di Vincenzo S, Del Campo F. Effect of alpha-1-blockade by prazosin on blood sugar, insulin and glucagon levels in normals and non-insulin dependent diabetics. J Endocrinol Invest 1983, 6:199-202.
    • (1983) J Endocrinol Invest , vol.6 , pp. 199-202
    • Ferlito, S.1    Puleo, F.2    Carra, G.3    Damante, G.4    Di Vincenzo, S.5    Del Campo, F.6
  • 53
    • 0026464754 scopus 로고
    • The glucoregulatory and antilipolytic actions of insulin in abdominal obesity with normal or impaired glucose tolerance: an in vivo and in vitro study
    • 10.1111/j.1365-2362.1992.tb01436.x, 1478241
    • Cavallo-Perin P, Bruno A, Cassader M, Cesco L, Gruden G, Pagano G. The glucoregulatory and antilipolytic actions of insulin in abdominal obesity with normal or impaired glucose tolerance: an in vivo and in vitro study. Eur J Clin Invest 1992, 22:725-731. 10.1111/j.1365-2362.1992.tb01436.x, 1478241.
    • (1992) Eur J Clin Invest , vol.22 , pp. 725-731
    • Cavallo-Perin, P.1    Bruno, A.2    Cassader, M.3    Cesco, L.4    Gruden, G.5    Pagano, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.