메뉴 건너뛰기




Volumn 50, Issue 3, 2001, Pages 589-596

Aprotinin impairs endothelium-dependent relaxation in rat aorta and inhibits nitric oxide release from rat coronary endothelial cells

Author keywords

Arteries; Cell culture isolation; Endothelial function; Nitric oxide; Vasoconstriction dilation

Indexed keywords

ACETYLCHOLINE; APROTININ; ARGININE; CALCIMYCIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; NITRITE; NITROPRUSSIDE SODIUM; PHENYLEPHRINE; POTASSIUM CHLORIDE; SERINE PROTEINASE INHIBITOR;

EID: 0034997704     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(01)00268-1     Document Type: Article
Times cited : (13)

References (24)
  • 1
    • 0024509887 scopus 로고
    • Reduction in blood loss and blood use after cardiopulmonary bypass with high-dose aprotinin (Trasylol)
    • Bidstrup B., Royston D., Sapsford R., Taylor K. Reduction in blood loss and blood use after cardiopulmonary bypass with high-dose aprotinin (Trasylol). J Thorac Cardiovasc Surg. 97:1989;364-372.
    • (1989) J Thorac Cardiovasc Surg , vol.97 , pp. 364-372
    • Bidstrup, B.1    Royston, D.2    Sapsford, R.3    Taylor, K.4
  • 2
    • 0033524140 scopus 로고    scopus 로고
    • Pharmacological strategies to decrease excessive blood loss in cardiac surgery: A meta-analysis of clinically relevant endpoints
    • Levi M., Cromheecke M.E., de Jonge E., et al. Pharmacological strategies to decrease excessive blood loss in cardiac surgery: a meta-analysis of clinically relevant endpoints. Lancet. 354:(9194):1999;1940-1947.
    • (1999) Lancet , vol.354 , Issue.9194 , pp. 1940-1947
    • Levi, M.1    Cromheecke, M.E.2    De Jonge, E.3
  • 3
    • 0026739962 scopus 로고
    • Aprotinin therapy for reoperative myocardial revascularisation: A placebo-controlled study
    • Cosgrove D.M. III, Heric B., Lytle B.W., et al. Aprotinin therapy for reoperative myocardial revascularisation: a placebo-controlled study. Ann Thorac Surg. 54:1992;1031-1038.
    • (1992) Ann Thorac Surg , vol.54 , pp. 1031-1038
    • Cosgrove D.M. III1    Heric, B.2    Lytle, B.W.3
  • 5
    • 0026743988 scopus 로고
    • Aprotinin increases release of von Willebrand factor in cultured human umblical vein endothelial cells
    • Havel M.P., Griesmacher A., Weigel G., et al. Aprotinin increases release of von Willebrand factor in cultured human umblical vein endothelial cells. Surgery. 112:1992;573-577.
    • (1992) Surgery , vol.112 , pp. 573-577
    • Havel, M.P.1    Griesmacher, A.2    Weigel, G.3
  • 8
    • 0031925002 scopus 로고    scopus 로고
    • Cardiopulmonary bypass-induced inflammation: Is it important?
    • Hill G.E. Cardiopulmonary bypass-induced inflammation: is it important? J Cardiothorac Vasc Anesth. 12:(2 Suppl 1):1998;21-25.
    • (1998) J Cardiothorac Vasc Anesth , vol.12 , Issue.2 SUPPL. 1 , pp. 21-25
    • Hill, G.E.1
  • 9
    • 0030896938 scopus 로고    scopus 로고
    • Aprotinin is associated with a decrease in nitric oxide production during cardiopulmonary bypass
    • Hill G.E., Springall D.R., Robbins R.A. Aprotinin is associated with a decrease in nitric oxide production during cardiopulmonary bypass. Surgery. 121:1997;449-455.
    • (1997) Surgery , vol.121 , pp. 449-455
    • Hill, G.E.1    Springall, D.R.2    Robbins, R.A.3
  • 10
    • 0031902013 scopus 로고    scopus 로고
    • Aprotinin reduces nitric oxide production in vitro and in vivo in a dose-dependent manner
    • Bruda N.L., Hurlbert B.J., Hill E.G. Aprotinin reduces nitric oxide production in vitro and in vivo in a dose-dependent manner. Clin Sci. 94:1998;505-509.
    • (1998) Clin Sci , vol.94 , pp. 505-509
    • Bruda, N.L.1    Hurlbert, B.J.2    Hill, E.G.3
  • 11
    • 0030916994 scopus 로고    scopus 로고
    • Aprotinin but not tranexamic acid inhibits cytokine-induced inducible nitric oxide synthase expression
    • Hill G.E., Robbins R.A. Aprotinin but not tranexamic acid inhibits cytokine-induced inducible nitric oxide synthase expression. Anesth Analg. 84:1997;1198-1202.
    • (1997) Anesth Analg , vol.84 , pp. 1198-1202
    • Hill, G.E.1    Robbins, R.A.2
  • 12
    • 0031032874 scopus 로고    scopus 로고
    • Differing effects of aprotinin and ε-aminocaproic acid on cytokine-induced inducible nitric oxide synthase expression
    • Hill G.E., Taylor J.A., Robbins A.R. Differing effects of aprotinin and ε-aminocaproic acid on cytokine-induced inducible nitric oxide synthase expression. Ann Thorac Surg. 63:1997;74-77.
    • (1997) Ann Thorac Surg , vol.63 , pp. 74-77
    • Hill, G.E.1    Taylor, J.A.2    Robbins, A.R.3
  • 13
    • 0032504539 scopus 로고    scopus 로고
    • Aprotinin, the first competitive protein inhibitor of NOS activity
    • Venturini G., Colasanti M., Ascenzi P. Aprotinin, the first competitive protein inhibitor of NOS activity. Biochem Biophys Res Commun. 249:1998;263-265.
    • (1998) Biochem Biophys Res Commun , vol.249 , pp. 263-265
    • Venturini, G.1    Colasanti, M.2    Ascenzi, P.3
  • 15
    • 0029004863 scopus 로고
    • Nitrate determination in biological fluids by an enzymatic one-step assay with nitrate reductase
    • Bories P.N., Bories C. Nitrate determination in biological fluids by an enzymatic one-step assay with nitrate reductase. Clin Chem. 41:(6):1995;904-907.
    • (1995) Clin Chem , vol.41 , Issue.6 , pp. 904-907
    • Bories, P.N.1    Bories, C.2
  • 17
    • 0021324750 scopus 로고
    • Enhanced responsiveness of rat isolated aorta to clonidine after removal of endothelial cells
    • Egleme C., Godfraind T., Miller R.C. Enhanced responsiveness of rat isolated aorta to clonidine after removal of endothelial cells. Br J Pharmacol. 81:1984;16-21.
    • (1984) Br J Pharmacol , vol.81 , pp. 16-21
    • Egleme, C.1    Godfraind, T.2    Miller, R.C.3
  • 19
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology and pharmacology
    • Moncada S., Palmer R.M.J., Higgs E.A.A. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev. 43:(2):1991;109-142.
    • (1991) Pharmacol Rev , vol.43 , Issue.2 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, E.A.A.3
  • 20
    • 0030887618 scopus 로고    scopus 로고
    • N-α-Tosyl-L-lysine chloromethylketone prevents expression of iNOS in vascular smooth muscle by blocking activation of NF κb
    • Schini-Kerth V.B., Boese M., Busse R., Fisslthaler B., Mülsch A. N-α-Tosyl-L-lysine chloromethylketone prevents expression of iNOS in vascular smooth muscle by blocking activation of NF κB. Arterioscler Thromb Vasc Biol. 17:1997;672-679.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 672-679
    • Schini-Kerth, V.B.1    Boese, M.2    Busse, R.3    Fisslthaler, B.4    Mülsch, A.5
  • 22
    • 0027300477 scopus 로고
    • Aprotinin in perspective
    • Westaby S. Aprotinin in perspective. Ann Thorac Surg. 55:1993;1033-1041.
    • (1993) Ann Thorac Surg , vol.55 , pp. 1033-1041
    • Westaby, S.1
  • 23
    • 0026525226 scopus 로고
    • Natural and synthetic antifibrinolytics in cardiac surgery
    • Hardy J.F., Desroches J. Natural and synthetic antifibrinolytics in cardiac surgery. Can J Anaesth. 39:1992;353-365.
    • (1992) Can J Anaesth , vol.39 , pp. 353-365
    • Hardy, J.F.1    Desroches, J.2
  • 24
    • 0029026874 scopus 로고
    • Analysis of aportinin on the mean arterial pressure, carotid artery blood flow, and hindlimb vascular resistance in the live rat, and pulmonary vascular resistance in the isolated perfused rat lung
    • Jahr J.S., Kaye A.D., Kang B., Feng C.J., Nossaman B.D. Analysis of aportinin on the mean arterial pressure, carotid artery blood flow, and hindlimb vascular resistance in the live rat, and pulmonary vascular resistance in the isolated perfused rat lung. J Med. 26:(1-2):1995;31-42.
    • (1995) J Med , vol.26 , Issue.12 , pp. 31-42
    • Jahr, J.S.1    Kaye, A.D.2    Kang, B.3    Feng, C.J.4    Nossaman, B.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.