-
1
-
-
0037631831
-
Insulin resistance and chronic cardiovascular inflammatory syndrome
-
Fernández-Real, J. M., Ricart, W., Insulin resistance and chronic cardiovascular inflammatory syndrome. Endocr. Rev. 2003, 24, 278-301.
-
(2003)
Endocr. Rev.
, vol.24
, pp. 278-301
-
-
Fernández-Real, J.M.1
Ricart, W.2
-
2
-
-
0348222671
-
Inflammation: the link between insulin resistance, obesity and diabetes
-
Dandona, P., Aljada, A., Bandyopadhyay, A., Inflammation: the link between insulin resistance, obesity and diabetes. Trend. Immunol. 2004, 25, 4-7.
-
(2004)
Trend. Immunol.
, vol.25
, pp. 4-7
-
-
Dandona, P.1
Aljada, A.2
Bandyopadhyay, A.3
-
3
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg, S. P., McCann, D., Desai, M., Rosenbaum, M. et al., Obesity is associated with macrophage accumulation in adipose tissue. J. Clin. Invest. 2003, 112, 1796-1808.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
-
4
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu, H., Barnes, G. T., Yang, Q., Tan, G. et al., Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J. Clin. Invest. 2003, 12, 1821-1830.
-
(2003)
J. Clin. Invest.
, vol.12
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
-
5
-
-
33745216724
-
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
-
Kanda, H., Tateya, S., Tamori, Y., Kotani, K. et al., MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J. Clin. Invest. 2006, 116, 1494-1505.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1494-1505
-
-
Kanda, H.1
Tateya, S.2
Tamori, Y.3
Kotani, K.4
-
6
-
-
33750602672
-
Mesenteric adipose tissue-derived monocyte chemoattractant protein-1 plays a crucial role in adipose tissue macrophage migration and activation in obese mice
-
Yu, R., Kim, C. S., Kwon, B. S., Kawada, T., Mesenteric adipose tissue-derived monocyte chemoattractant protein-1 plays a crucial role in adipose tissue macrophage migration and activation in obese mice. Obesity 2006, 14, 1353-1362.
-
(2006)
Obesity
, vol.14
, pp. 1353-1362
-
-
Yu, R.1
Kim, C.S.2
Kwon, B.S.3
Kawada, T.4
-
7
-
-
26244448904
-
A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor α
-
Suganami, T., Nishida, J., Ogawa, Y., A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor α. Arterioscler. Thromb. Vasc. Biol. 2005, 25, 2062-2068.
-
(2005)
Arterioscler. Thromb. Vasc. Biol.
, vol.25
, pp. 2062-2068
-
-
Suganami, T.1
Nishida, J.2
Ogawa, Y.3
-
8
-
-
0027459878
-
Adipose expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance
-
Hotamisligil, G. S., Shargill, N. S., Spiegelman, B. M., Adipose expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance. Science 1993, 259, 87-91.
-
(1993)
Science
, vol.259
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
9
-
-
0028362194
-
Tumor necrosis factor alpha inhibits signaling from the insulin receptor
-
Hotamisligil, G. S., Murray, D. S., Choy, L. N., Spiegelman, B. M., Tumor necrosis factor alpha inhibits signaling from the insulin receptor. Proc. Natl. Acad. Sci. USA 1994, 91, 4854-4858.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 4854-4858
-
-
Hotamisligil, G.S.1
Murray, D.S.2
Choy, L.N.3
Spiegelman, B.M.4
-
10
-
-
0037059777
-
Mapping of early signaling events in tumor necrosis factor-alpha -mediated lipolysis in human fat cells
-
Ryden, M., Dicker, A., Harmelen, V., Hauner, H. et al., Mapping of early signaling events in tumor necrosis factor-alpha -mediated lipolysis in human fat cells. J. Biol. Chem. 2002, 277, 1085-1091.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1085-1091
-
-
Ryden, M.1
Dicker, A.2
Harmelen, V.3
Hauner, H.4
-
11
-
-
34347399563
-
Metabolic endotoxemia initiates obesity and insulin resistance
-
Cani, P. D., Amar J., Iglesias M. A., Poggi M. et al., Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes 2007, 56, 1761-72.
-
(2007)
Diabetes
, vol.56
, pp. 1761-1772
-
-
Cani, P.D.1
Amar, J.2
Iglesias, M.A.3
Poggi, M.4
-
12
-
-
0034713444
-
Roles of PPARs in health and disease
-
Kersten, S., Desvergne, B., Wahli, W., Roles of PPARs in health and disease. Nature 2000, 405, 421-424.
-
(2000)
Nature
, vol.405
, pp. 421-424
-
-
Kersten, S.1
Desvergne, B.2
Wahli, W.3
-
13
-
-
0842263981
-
The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity
-
Ferré, P. The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity. Diabetes 2004, 53(Suppl 1), S43-S50.
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 1
-
-
Ferré, P.1
-
14
-
-
0035132330
-
PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
-
Chawla, A., Barak, Y., Nagy, L., Liao, D. et al., PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nat. Med. 2001, 7, 48-52.
-
(2001)
Nat. Med
, vol.7
, pp. 48-52
-
-
Chawla, A.1
Barak, Y.2
Nagy, L.3
Liao, D.4
-
15
-
-
0034114650
-
Evaluation of auraptene content in citrus fruits and their products
-
Ogawa, K., Kawasaki, A., Yoshida, T., Nesumi, H. et al., Evaluation of auraptene content in citrus fruits and their products. J. Agric. Food Chem. 2000, 48, 1763-1769.
-
(2000)
J. Agric. Food Chem.
, vol.48
, pp. 1763-1769
-
-
Ogawa, K.1
Kawasaki, A.2
Yoshida, T.3
Nesumi, H.4
-
16
-
-
79551621245
-
Auraptene: a natural biologically active compound with multiple targets
-
Genovese, S., Epifano, F., Auraptene: a natural biologically active compound with multiple targets. Curr. Drug Targets 2011, 12, 381-386.
-
(2011)
Curr. Drug Targets
, vol.12
, pp. 381-386
-
-
Genovese, S.1
Epifano, F.2
-
17
-
-
65449152857
-
Auraptene, a citrus fruit compound, regulates gene expression as a PPAR-alpha agonist in HepG2 hepatocytes
-
Takahashi, N., Kang, M. S., Kuroyanagi, K., Goto, T. et al., Auraptene, a citrus fruit compound, regulates gene expression as a PPAR-alpha agonist in HepG2 hepatocytes. Biofactors 2008, 33, 25-32.
-
(2008)
Biofactors
, vol.33
, pp. 25-32
-
-
Takahashi, N.1
Kang, M.S.2
Kuroyanagi, K.3
Goto, T.4
-
18
-
-
37549021158
-
Citrus auraptene acts as an agonist for PPARs and enhances adiponectin production and MCP-1 reduction in 3T3-L1 adipocytes
-
Kuroyanagi, K., Kang, M. S., Goto, T., Hirai, S. et al., Citrus auraptene acts as an agonist for PPARs and enhances adiponectin production and MCP-1 reduction in 3T3-L1 adipocytes. Biochem. Biophys. Res. Commun. 2008, 366, 219-225.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.366
, pp. 219-225
-
-
Kuroyanagi, K.1
Kang, M.S.2
Goto, T.3
Hirai, S.4
-
19
-
-
80051988435
-
An in vitro analysis system using a fluorescence protein reporter for evaluating anti-inflammatory effects in macrophages
-
Sakamoto, T., Yamaguchi, Y., Goto, T., Takahashi, N. et al., An in vitro analysis system using a fluorescence protein reporter for evaluating anti-inflammatory effects in macrophages. Biosci. Biotechnol. Biochem. 2011, 75, 1582-1587.
-
(2011)
Biosci. Biotechnol. Biochem.
, vol.75
, pp. 1582-1587
-
-
Sakamoto, T.1
Yamaguchi, Y.2
Goto, T.3
Takahashi, N.4
-
20
-
-
18344374193
-
Dual action of isoprenols from herbal medicines on both PPARgamma and PPAR-alpha in 3T3-L1 adipocytes and HepG2 hepatocytes
-
Takahashi, N., Kawada, T., Goto, T., Yamamoto, T., Dual action of isoprenols from herbal medicines on both PPARgamma and PPAR-alpha in 3T3-L1 adipocytes and HepG2 hepatocytes. FEBS Lett. 2002, 514, 315-322.
-
(2002)
FEBS Lett.
, vol.514
, pp. 315-322
-
-
Takahashi, N.1
Kawada, T.2
Goto, T.3
Yamamoto, T.4
-
21
-
-
35148882512
-
Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages
-
Hirai, S., Kim, Y. I., Goto, T., Kang, M. S. et al., Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages. Life Sci. 2007, 81, 1272-1279.
-
(2007)
Life Sci.
, vol.81
, pp. 1272-1279
-
-
Hirai, S.1
Kim, Y.I.2
Goto, T.3
Kang, M.S.4
-
22
-
-
40849135613
-
Dehydroabietic acid, herbal terpenoid, acts as ligands for PPARs in macrophages to regulate inflammation
-
Kang, M. S., Hirai, S., Goto, T., Kuroyanagi, K. et al., Dehydroabietic acid, herbal terpenoid, acts as ligands for PPARs in macrophages to regulate inflammation. Biochem. Biophys. Res. Commun. 2008, 369, 333-338.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.369
, pp. 333-338
-
-
Kang, M.S.1
Hirai, S.2
Goto, T.3
Kuroyanagi, K.4
-
23
-
-
0142102510
-
Abietic acid activates PPAR-gamma in RAW264. Macrophages and 3T3-L1 adipocytes to regulate gene expression involved in inflammation and lipid metabolism
-
Takahashi, N., Kawada, T., Goto, T., Kim, C. S. et al., Abietic acid activates PPAR-gamma in RAW264. Macrophages and 3T3-L1 adipocytes to regulate gene expression involved in inflammation and lipid metabolism. FEBS Lett. 2003, 550, 190-194.
-
(2003)
FEBS Lett.
, vol.550
, pp. 190-194
-
-
Takahashi, N.1
Kawada, T.2
Goto, T.3
Kim, C.S.4
-
24
-
-
0037053361
-
Overexpression and ribozyme-mediated targeting of transcriptional coactivators CBP and p300 revealed their indispensable roles in adipocyte differentiation through the regulation of PPAR-gamma
-
Takahashi, N., Kawada, T., Yamamoto, T., Goto, T. et al., Overexpression and ribozyme-mediated targeting of transcriptional coactivators CBP and p300 revealed their indispensable roles in adipocyte differentiation through the regulation of PPAR-gamma. J. Biol. Chem. 2002, 277, 16906-16912.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 16906-16912
-
-
Takahashi, N.1
Kawada, T.2
Yamamoto, T.3
Goto, T.4
-
25
-
-
26444457309
-
Phytol directly activates PPAR-alpha and regulates gene expression involved in lipid metabolism in PPAR-alpha-expressing HepG2 hepatocytes
-
Goto, T., Takahashi, N., Kato, S., Egawa, K. et al., Phytol directly activates PPAR-alpha and regulates gene expression involved in lipid metabolism in PPAR-alpha-expressing HepG2 hepatocytes. Biochem. Biophys. Res. Commun. 2005, 337, 440-445.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.337
, pp. 440-445
-
-
Goto, T.1
Takahashi, N.2
Kato, S.3
Egawa, K.4
-
26
-
-
77954014957
-
Diosgenin attenuates inflammatory changes in the interaction between adipocytes and macrophages
-
Hirai, S., Uemura, T., Mizoguchi, N., Lee, J. Y. et al., Diosgenin attenuates inflammatory changes in the interaction between adipocytes and macrophages. Mol. Nutr. Food Res. 2010, 54, 797-804.
-
(2010)
Mol. Nutr. Food Res.
, vol.54
, pp. 797-804
-
-
Hirai, S.1
Uemura, T.2
Mizoguchi, N.3
Lee, J.Y.4
-
27
-
-
71749121785
-
Luteolin, a food-derived flavonoid, suppresses adipocyte-dependent activation of macrophages by inhibiting JNK activation
-
Ando, C., Takahashi, N., Hirai, S., Nichimura, K. et al., Luteolin, a food-derived flavonoid, suppresses adipocyte-dependent activation of macrophages by inhibiting JNK activation. FEBS Lett. 2009, 583, 3649-3654.
-
(2009)
FEBS Lett.
, vol.583
, pp. 3649-3654
-
-
Ando, C.1
Takahashi, N.2
Hirai, S.3
Nichimura, K.4
-
28
-
-
71849104860
-
Protein measurement with the Folin phenol reagent
-
Lowry, O. H., Rosebrough, N. J., Farr, A. L., Randall, R. J., Protein measurement with the Folin phenol reagent. J. Biol. Chem. 1951, 193, 265-275.
-
(1951)
J. Biol. Chem.
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
29
-
-
0035104119
-
LPS induction of gene expression in human monocytes
-
Guha, M., Mackman, N., LPS induction of gene expression in human monocytes. Cell. Signal 2001, 13, 85-94.
-
(2001)
Cell. Signal
, vol.13
, pp. 85-94
-
-
Guha, M.1
Mackman, N.2
-
30
-
-
0034075996
-
Suppression of N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis by dietary feeding of auraptene
-
Kawabata, K., Tanaka, T., Yamamoto, T., Hara, A. et al., Suppression of N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis by dietary feeding of auraptene. J. Exp. Clin. Cancer Res. 2000, 19, 45-52.
-
(2000)
J. Exp. Clin. Cancer Res.
, vol.19
, pp. 45-52
-
-
Kawabata, K.1
Tanaka, T.2
Yamamoto, T.3
Hara, A.4
-
31
-
-
82955170675
-
Auraptene regulates gene expression involved in lipid metabolism through PPARα activation in diabetic obese mice
-
Takahashi, N., Senda, M., Lin, S., Goto, T. et al., Auraptene regulates gene expression involved in lipid metabolism through PPARα activation in diabetic obese mice. Mol. Nutr. Food Res. 2011, 55, 1791-1797.
-
(2011)
Mol. Nutr. Food Res.
, vol.55
, pp. 1791-1797
-
-
Takahashi, N.1
Senda, M.2
Lin, S.3
Goto, T.4
-
32
-
-
0031888958
-
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
-
Jiang, C., Ting, A. T., Seed, B., PPAR-γ agonists inhibit production of monocyte inflammatory cytokines. Nature 1998, 391, 82-86.
-
(1998)
Nature
, vol.391
, pp. 82-86
-
-
Jiang, C.1
Ting, A.T.2
Seed, B.3
-
33
-
-
0012929728
-
Toll-like receptors
-
Takeda, K., Kaisho, T., Akira, S., Toll-like receptors. Annu. Rev. Immunol. 2003, 21, 335-376.
-
(2003)
Annu. Rev. Immunol.
, vol.21
, pp. 335-376
-
-
Takeda, K.1
Kaisho, T.2
Akira, S.3
-
34
-
-
0035907302
-
Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4
-
Lee, J. Y., Sohn, K. H., Rhee, S. H., Hwang, D., Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. J. Biol. Chem. 2001, 276, 16683-16689.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16683-16689
-
-
Lee, J.Y.1
Sohn, K.H.2
Rhee, S.H.3
Hwang, D.4
-
35
-
-
33750584214
-
TLR4 links innate immunity and fatty acid-induced insulin resistance
-
Shi, H., Kokoeva, M. V., Inouye, K., Tzameli, I. et al., TLR4 links innate immunity and fatty acid-induced insulin resistance. J. Clin. Invest. 2006, 116, 3015-3025.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 3015-3025
-
-
Shi, H.1
Kokoeva, M.V.2
Inouye, K.3
Tzameli, I.4
-
36
-
-
0033782926
-
Suppression by citrus auraptene of phorbol ester-and endotoxin-induced inflammatory responses: role of attenuation of leukocyte activation
-
Murakami, A., Nakamura, Y., Tanaka, T., Kawabata, K. et al., Suppression by citrus auraptene of phorbol ester-and endotoxin-induced inflammatory responses: role of attenuation of leukocyte activation. Carcinogenesis 2000, 21, 1843-1850.
-
(2000)
Carcinogenesis
, vol.21
, pp. 1843-1850
-
-
Murakami, A.1
Nakamura, Y.2
Tanaka, T.3
Kawabata, K.4
-
37
-
-
0038059372
-
Effects of selected food factors with chemopreventive properties on combined lipopolysaccharide- and interferon-γ-induced IκB degradation in RAW264.7 macrophages
-
Murakami, A., Matsumoto, K., Koshimizu, K., Ohigashi, H., Effects of selected food factors with chemopreventive properties on combined lipopolysaccharide- and interferon-γ-induced IκB degradation in RAW264.7 macrophages. Cancer Lett. 2003, 195, 17-25.
-
(2003)
Cancer Lett.
, vol.195
, pp. 17-25
-
-
Murakami, A.1
Matsumoto, K.2
Koshimizu, K.3
Ohigashi, H.4
-
38
-
-
33748803350
-
Citrus auraptene targets translation of MMP-7 (matrilysin) via ERK1/2-dependent and mTOR-independent mechanism
-
Kawabata, K., Murakami, A., Ohigashi, H., Citrus auraptene targets translation of MMP-7 (matrilysin) via ERK1/2-dependent and mTOR-independent mechanism. FEBS Lett. 2006, 580, 5288-5294.
-
(2006)
FEBS Lett.
, vol.580
, pp. 5288-5294
-
-
Kawabata, K.1
Murakami, A.2
Ohigashi, H.3
-
39
-
-
0032698069
-
The p38 mitogen-activated protein kinase is required for NF-κB-dependent gene expression
-
Carter, A. B., Knudtson, K. L., Monick, M. M., Hunninghake, G. W., The p38 mitogen-activated protein kinase is required for NF-κB-dependent gene expression. J. Biol. Chem. 1999, 274, 30858-30863.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 30858-30863
-
-
Carter, A.B.1
Knudtson, K.L.2
Monick, M.M.3
Hunninghake, G.W.4
-
40
-
-
77956129930
-
Icariin derivative inhibits inflammation through suppression of p38 mitogen-activated protein kinase and nuclear factor-κB pathways
-
Chen, S. R., Xu, X. Z., Wang, Y. H., Chen, J. W. et al., Icariin derivative inhibits inflammation through suppression of p38 mitogen-activated protein kinase and nuclear factor-κB pathways. Biol. Pharm. Bull. 2010, 33, 1307-1313.
-
(2010)
Biol. Pharm. Bull.
, vol.33
, pp. 1307-1313
-
-
Chen, S.R.1
Xu, X.Z.2
Wang, Y.H.3
Chen, J.W.4
|