Rapid loss of efficacy to the antiseizure drugs lamotrigine and carbamazepine: A novel experimental model of pharmacoresistant epilepsy

Epilepsia

Volumn 54, Issue 7, 2013, Pages 1186-1194

  Srivastava, Ajay K ^a   Alex, Anitha B ^a   Wilcox, Karen S ^a   Steve White, H ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

Carbamazepine; Kindling; Lamotrigine; Pharmacoresistance; Seizure animal model

Indexed keywords

CARBAMAZEPINE; LAMOTRIGINE; RETIGABINE;

ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; EPILEPSY; IN VITRO STUDY; KINDLING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE;

CARBAMAZEPINE; KINDLING; LAMOTRIGINE; PHARMACORESISTANCE; SEIZURE ANIMAL MODEL;

ACTION POTENTIALS; ANIMALS; ANTICONVULSANTS; BIOPHYSICS; CARBAMAZEPINE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; ELECTRIC STIMULATION; EPILEPSY; HIPPOCAMPUS; KINDLING, NEUROLOGIC; MALE; NEURONS; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; TRIAZINES;

EID: 84879794951     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/epi.12234     Document Type: Article

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