The scorpion toxin Amm VIII induces pain hypersensitivity through gain-of-function of TTX-sensitive Na+ channels

Pain

Volumn 154, Issue 8, 2013, Pages 1204-1215

  Abbas, Najwa ^a   Gaudioso Tyzra, Christelle ^a   Bonnet, Caroline ^a   Gabriac, Mélanie ^a   Amsalem, Muriel ^a   Lonigro, Aurélie ^a   Padilla, Françoise ^a   Crest, Marcel ^a   Martin Eauclaire, Marie France ^a   Delmas, Patrick ^a  

^a University of Mediterranée   (France)

Author keywords

Allodynia; Excitability; Hyperalgesia; Nav1.7; Nav1.8; Nav1.9; Pain; Scorpion toxins; Sensory neurons; Voltage gated sodium channels

Indexed keywords

AMM VIII; SCORPION ALPHA TOXIN; SCORPION VENOM; SODIUM CHANNEL NAV1.4; TETRODOTOXIN; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

ACTION POTENTIAL; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GAIN OF FUNCTION MUTATION; GENE EXPRESSION; HYPERALGESIA; MALE; MOUSE; NERVE CONDUCTION; NERVE EXCITABILITY; NONHUMAN; ONCOGENE C FOS; PAIN; PAIN HYPERSENSITIVITY; PRIORITY JOURNAL; SENSORY NERVE; SENSORY NERVE CELL; SPIKE; SPINAL GANGLION;

EID: 84879781754     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2013.03.037     Document Type: Article

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