Prostacyclin and PPARα Agonists Control Vascular Smooth Muscle Cell Apoptosis and Phenotypic Switch through Distinct 14-3-3 Isoforms

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Chen, Yen Chung ^a   Chu, Ling Yun ^a   Yang, Shu Fan ^a   Chen, Hua Ling ^a   Yet, Shaw Fang ^a   Wu, Kenneth K ^a,b,c  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

14 3 3; apoptosis; peroxisome proliferator activated receptor; phenotypic switch; prostacyclin; smooth muscle cell

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; CALPONIN; CALPONIN 1; CARBACYCLIN; CASPASE 3; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ANTAGONIST; PIRINIXIC ACID; PROCASPASE 3; PROSTACYCLIN; PROTEIN BAD; PROTEIN BCL 2; PROTEIN BCL W; PROTEIN BCL XL; TRANSGELIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL COUNT; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; MITOCHONDRION; NONHUMAN; PHENOTYPE; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR SMOOTH MUSCLE;

14-3-3; APOPTOSIS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PHENOTYPIC SWITCH; PROSTACYCLIN; SMOOTH MUSCLE CELL;

14-3-3 PROTEINS; ANIMALS; APOPTOSIS; BCL-ASSOCIATED DEATH PROTEIN; EPOPROSTENOL; HYDROGEN PEROXIDE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHENOTYPE; PPAR ALPHA; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEOLYSIS; PYRIMIDINES; RATS;

RATTUS;

EID: 84879765009     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0069702     Document Type: Article

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