Male-specific alteration in excitatory post-synaptic development and social interaction in pre-natal valproic acid exposure model of autism spectrum disorder

Journal of Neurochemistry

Volumn 124, Issue 6, 2013, Pages 832-843

  Kim, Ki Chan ^a,b   Kim, Pitna ^b,c   Go, Hyo Sang ^a,b   Choi, Chang Soon ^b,c   Park, Jin Hee ^c   Kim, Hee Jin ^d   Jeon, Se Jin ^e   Dela Pena, Ike Campomayor ^d   Han, Seol Heui ^b,c   Cheong, Jae Hoon ^d   Ryu, Jong Hoon ^f   Shin, Chan Young ^b,c  

^a Seoul National University   (South Korea)

^b Konkuk University   (South Korea)

^c Konkuk University School of Medicine   (South Korea)

^d Sahmyook University   (South Korea)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f Kyung Hee University   (South Korea)

Author keywords

autism spectrum disorder; glutamatergic synapse; male preponderance; seizure susceptibility; social interaction; valproic acid

Indexed keywords

4 AMINOBUTYRIC ACID; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; GLUTAMATE DECARBOXYLASE; GLUTAMIC ACID; POSTSYNAPTIC DENSITY PROTEIN 95; VALPROIC ACID; VESICULAR GLUTAMATE TRANSPORTER 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTISM; CONTROLLED STUDY; DISEASE MODEL; ELECTRIC SHOCK; ELECTRON MICROSCOPY; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; MALE; NERVE CELL; NERVE CELL DIFFERENTIATION; NONHUMAN; POSTSYNAPTIC MEMBRANE; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; RAT; SEX DIFFERENCE; SOCIAL INTERACTION; SYNAPTOGENESIS;

ANIMALS; CHILD; CHILD DEVELOPMENT DISORDERS, PERVASIVE; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; INTERPERSONAL RELATIONS; MALE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SEX CHARACTERISTICS; SYNAPSES; SYNAPTIC POTENTIALS; VALPROIC ACID;

ANIMALIA; RATTUS; RODENTIA;

EID: 84874702940     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12147     Document Type: Article

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